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The map label for this gene is 37521459

Identifier: 37521459

GI number: 37521459

Start: 2010121

End: 2011125

Strand: Reverse

Name: 37521459

Synonym: gll1890

Alternate gene names: NA

Gene position: 2011125-2010121 (Counterclockwise)

Preceding gene: 37521460

Following gene: 37521458

Centisome position: 43.17

GC content: 57.21

Gene sequence:

>1005_bases
ATGGAGGAATTCGTAATGTTTGGTACCTTTCGATCTTTGAGTGCTTGCCTACTGCTCGCTGCAAGCGTAGCAGCCTATGT
GACGGCGGCTCCGACGGCCGCTTATGCCCAAACCGTCGACACGACCACCAGTAACAATGCACTCTCCAATGGAACGAAAG
TGGATCCGCTAGAAGTCGACGGTGTTTACGTGTTTGGCGACAGTCTGGTCGATACCGGAAACGTCTTCAACGCAAACGGC
GGCGTGTTTCCCCCCAGCCCGCCTTACTTTTCGGGTCGTTTCTCCAACGGTCCGCTCTGGATCGAGAATGTCCTGGCCCC
TTTGGGCATCAACCTGGTGCCCAGTACCACGGCGGGAGGGCAAAACTTTGCCTTTGGCGGTGCTCCCTCGGGCTTTTTCT
TGGAGCAGCCCATTCCTCTTGGTGGCCCCCCCCCGGAGACACCGGGCCTGCTCTACCAGCTCGGTACCTTTACTCAGCCG
GCGCCACAGGTCACACCCCAGACGCTCTACTTCATCTCCGCAGGCAGCAACGATCTTCTGAACGATTTTCTGGCCAATCG
CGAACTGGACTATAACGTCCCGGTCCAGAACCTGACAACCGCGGTGGCAACGCTGTACGCCTATGGTGCGCGCAATATCG
TCATCAGCAACATCCCGGATCTTAGCCGGGCTCCGCTCACGCAGGTCAACCCGGGCGAATTGCCTACGCTGAAGGATCAG
GTGAAGCTTGCTAACAAGTACATCAAGATCGCCTTGCAGGAATTGAAACAGTCACGACCCGGTTTGAACACCATCCTCCT
GGACTTCTACACCAGATTCAACAAGTTTCTCGACGCTCCCCAAGACTACGGCCTCACGAACACTATCTCGCCCTGTCTGA
CGGCCGTGGCGGTGTGTGCGAACCCCGATGAATACCTGTTCTGGGACGAAGTGCACCCGACGGCAGCCGTCGGGCAGGAG
CTGGCGGAGTTTTTCACCGGTACGATCTTTACATCAAGCCCCTAG

Upstream 100 bases:

>100_bases
AGTGAATATGCGTCGAGGGCGATGTGAACCGCATTGCCAGCAAAGCCGTGTGAGTACACCCCAACTCTCGCTTTGGTAAA
GACGATCAATCAGCTCTACA

Downstream 100 bases:

>100_bases
GCCAAGTGACGCAGGATCTCAGGGCCAGGCTTCAATGATTGCAGGCCGCCGCAACTACGGGTCTACAGGGGGAAAAACCA
GTCGCAGCGCTCCCGTTTGT

Product: hypothetical protein

Products: NA

Alternate protein names: TL; Atypical phospholipase; Lecithin-dependent hemolysin; LDH; Lysophospholipase; Phospholipase A2 [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MEEFVMFGTFRSLSACLLLAASVAAYVTAAPTAAYAQTVDTTTSNNALSNGTKVDPLEVDGVYVFGDSLVDTGNVFNANG
GVFPPSPPYFSGRFSNGPLWIENVLAPLGINLVPSTTAGGQNFAFGGAPSGFFLEQPIPLGGPPPETPGLLYQLGTFTQP
APQVTPQTLYFISAGSNDLLNDFLANRELDYNVPVQNLTTAVATLYAYGARNIVISNIPDLSRAPLTQVNPGELPTLKDQ
VKLANKYIKIALQELKQSRPGLNTILLDFYTRFNKFLDAPQDYGLTNTISPCLTAVAVCANPDEYLFWDEVHPTAAVGQE
LAEFFTGTIFTSSP

Sequences:

>Translated_334_residues
MEEFVMFGTFRSLSACLLLAASVAAYVTAAPTAAYAQTVDTTTSNNALSNGTKVDPLEVDGVYVFGDSLVDTGNVFNANG
GVFPPSPPYFSGRFSNGPLWIENVLAPLGINLVPSTTAGGQNFAFGGAPSGFFLEQPIPLGGPPPETPGLLYQLGTFTQP
APQVTPQTLYFISAGSNDLLNDFLANRELDYNVPVQNLTTAVATLYAYGARNIVISNIPDLSRAPLTQVNPGELPTLKDQ
VKLANKYIKIALQELKQSRPGLNTILLDFYTRFNKFLDAPQDYGLTNTISPCLTAVAVCANPDEYLFWDEVHPTAAVGQE
LAEFFTGTIFTSSP
>Mature_334_residues
MEEFVMFGTFRSLSACLLLAASVAAYVTAAPTAAYAQTVDTTTSNNALSNGTKVDPLEVDGVYVFGDSLVDTGNVFNANG
GVFPPSPPYFSGRFSNGPLWIENVLAPLGINLVPSTTAGGQNFAFGGAPSGFFLEQPIPLGGPPPETPGLLYQLGTFTQP
APQVTPQTLYFISAGSNDLLNDFLANRELDYNVPVQNLTTAVATLYAYGARNIVISNIPDLSRAPLTQVNPGELPTLKDQ
VKLANKYIKIALQELKQSRPGLNTILLDFYTRFNKFLDAPQDYGLTNTISPCLTAVAVCANPDEYLFWDEVHPTAAVGQE
LAEFFTGTIFTSSP

Specific function: Phospholipase hydrolyzing both fatty acid esters of phospholipid, i.e., it hydrolyzes phosphatidylcholine (PC) to lysophosphatidylcholine (LPC) and then LPC to glycerophosphorylcholine (GPC) [H]

COG id: COG3240

COG function: function code IR; Phospholipase/lecithinase/hemolysin

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDSL' lipolytic enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR001087
- InterPro:   IPR008265 [H]

Pfam domain/function: PF00657 Lipase_GDSL [H]

EC number: NA

Molecular weight: Translated: 35740; Mature: 35740

Theoretical pI: Translated: 4.07; Mature: 4.07

Prosite motif: PS00583 PFKB_KINASES_1 ; PS01098 LIPASE_GDSL_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEFVMFGTFRSLSACLLLAASVAAYVTAAPTAAYAQTVDTTTSNNALSNGTKVDPLEVD
CCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEC
GVYVFGDSLVDTGNVFNANGGVFPPSPPYFSGRFSNGPLWIENVLAPLGINLVPSTTAGG
CEEEECCCEECCCCEEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHHCCCEECCCCCCCC
QNFAFGGAPSGFFLEQPIPLGGPPPETPGLLYQLGTFTQPAPQVTPQTLYFISAGSNDLL
CCCCCCCCCCCCEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCHHH
NDFLANRELDYNVPVQNLTTAVATLYAYGARNIVISNIPDLSRAPLTQVNPGELPTLKDQ
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHH
VKLANKYIKIALQELKQSRPGLNTILLDFYTRFNKFLDAPQDYGLTNTISPCLTAVAVCA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
NPDEYLFWDEVHPTAAVGQELAEFFTGTIFTSSP
CCCCEEEECCCCCHHHHHHHHHHHHHCCEEECCC
>Mature Secondary Structure
MEEFVMFGTFRSLSACLLLAASVAAYVTAAPTAAYAQTVDTTTSNNALSNGTKVDPLEVD
CCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEC
GVYVFGDSLVDTGNVFNANGGVFPPSPPYFSGRFSNGPLWIENVLAPLGINLVPSTTAGG
CEEEECCCEECCCCEEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHHCCCEECCCCCCCC
QNFAFGGAPSGFFLEQPIPLGGPPPETPGLLYQLGTFTQPAPQVTPQTLYFISAGSNDLL
CCCCCCCCCCCCEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCHHH
NDFLANRELDYNVPVQNLTTAVATLYAYGARNIVISNIPDLSRAPLTQVNPGELPTLKDQ
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHH
VKLANKYIKIALQELKQSRPGLNTILLDFYTRFNKFLDAPQDYGLTNTISPCLTAVAVCA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
NPDEYLFWDEVHPTAAVGQELAEFFTGTIFTSSP
CCCCEEEECCCCCHHHHHHHHHHHHHCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3508495; 12620739; 1791426 [H]