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The map label for this gene is mrdB [H]

Identifier: 37521055

GI number: 37521055

Start: 1595150

End: 1596406

Strand: Direct

Name: mrdB [H]

Synonym: glr1486

Alternate gene names: 37521055

Gene position: 1595150-1596406 (Clockwise)

Preceding gene: 37521054

Following gene: 37521056

Centisome position: 34.24

GC content: 61.97

Gene sequence:

>1257_bases
ATGGAGCTGGCCAAACTTTCCTGGAACAGCTGGCTGAATTCGCTCTACAAGTTGTTTCGCGGCTTCGACGGCTGGCTGCT
GCTCTTTGCGGTGCTGTTGTTGTCGACGGGGGTGCTGACCATCTTCAGCACCCGCCCGGAAGGCATCGAATGGAAAGCCC
AGTTGGGCACGGGCCTGGTGGGCATCGCCTGGGCGCTGTTTTTGTCGCGGCTTACCTACGGCTGGCTGCAGCGCTGGAGC
TGGCTGATTTATAGCTCCGCCTGCGCAATGCTTTTAGGGGTGCTCTTCACCGGAAACTCGGTCAAGGGCGCCCAGCGCTG
GATCGAATTTGGGGGCATCCAGCTGCAGCCGAGCGAATTTGCCAAATTGGGGGTGATCATCGCCCTCGCCGCCCTCATCC
AGCGCTATCCCATCCGCAGCTTCGGCCAGATCTGGGTGGTGCTTGGGGTGCTGGCGGTGCCCTTTTTGCTGGTCTTCAAA
CAACCCGACCTGGGGACCGCCCTCGTCTTCGGCGCCATCAGCCTCGGCATGCTCTACTGGGGCGGGGCGCGGCTGGGCTG
GCTGGCATTGGTCGTCTCGCCGCTCATGGCCGCGATTCTATACGCCATCTGGATCCCGGCCTGGATTGTCTGGGTAGCGG
CCATGGCGGTGGTCGCCTGGCGGGAGTTGGACTGGCGGTGGTGGGGGGCGATCGGCGCCGGGGCGATCAACCTGGTGGCG
GGGGGACTGGGGCAGGTCTTCTGGCATCTGCTCAAGCCTTATCAGCAGCAGCGCCTCGTCGTCTTTCTCGATCCGAGCGG
CGACCCGCTGGGCTCCGGTTACCACATTCTGCAATCGGAAATTGCCATCGGAGCGGGGGGGCTCTGGGGGCGCGGCATAT
TCCAGGGCACCCAGACCCAGCTCAACTTCATCCCCGAGCAACATACCGACTTTATCTTCTCGGCCCTGGGCGAAGAGTGG
GGATTTCTGGGGGCGGTGGTGCTGTTGGGTTTGTTCTTTTGTTTGTTTGCCCGCCTGCTGCTCATCGCCCAGAACTCCGC
CGACGACTTCGGTTCGCTTTTGACTATCGGCGTGTTCACGATGCTGCTGTTCCAGACGGTGGTCAACATCGGCATGACGA
TCGGCCTGGCGCCGGTGACGGGCATTCCGCTGCCGTTTGTCACCTTCGGGCGCTCGTTTTTGATTACTTGCTTTACGGCG
ATCGGATTGGTGGAGTCGGTGGCGCTGCACCGCACCAAGATGGTCTTTCCGAACTAA

Upstream 100 bases:

>100_bases
TATTTGTCTGCAGGTTTGCCCGGTCAATGGTGCGATCCTGCCCGAAGAAAAACCGGAGCTTCAGAAGACGCCCACCTGAT
TTGTCGCTGCTTGAGGTGCT

Downstream 100 bases:

>100_bases
TTCCCATGGCTGATTGCATCCGTTTGCGGGAGATCGTCTGCTACGGCTACAGCGGTGTGTATGCCGAGGAGCGCCGCCTC
GGCCAGCGCTTCATCGTCGA

Product: rod-shape-determining protein MrdB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MELAKLSWNSWLNSLYKLFRGFDGWLLLFAVLLLSTGVLTIFSTRPEGIEWKAQLGTGLVGIAWALFLSRLTYGWLQRWS
WLIYSSACAMLLGVLFTGNSVKGAQRWIEFGGIQLQPSEFAKLGVIIALAALIQRYPIRSFGQIWVVLGVLAVPFLLVFK
QPDLGTALVFGAISLGMLYWGGARLGWLALVVSPLMAAILYAIWIPAWIVWVAAMAVVAWRELDWRWWGAIGAGAINLVA
GGLGQVFWHLLKPYQQQRLVVFLDPSGDPLGSGYHILQSEIAIGAGGLWGRGIFQGTQTQLNFIPEQHTDFIFSALGEEW
GFLGAVVLLGLFFCLFARLLLIAQNSADDFGSLLTIGVFTMLLFQTVVNIGMTIGLAPVTGIPLPFVTFGRSFLITCFTA
IGLVESVALHRTKMVFPN

Sequences:

>Translated_418_residues
MELAKLSWNSWLNSLYKLFRGFDGWLLLFAVLLLSTGVLTIFSTRPEGIEWKAQLGTGLVGIAWALFLSRLTYGWLQRWS
WLIYSSACAMLLGVLFTGNSVKGAQRWIEFGGIQLQPSEFAKLGVIIALAALIQRYPIRSFGQIWVVLGVLAVPFLLVFK
QPDLGTALVFGAISLGMLYWGGARLGWLALVVSPLMAAILYAIWIPAWIVWVAAMAVVAWRELDWRWWGAIGAGAINLVA
GGLGQVFWHLLKPYQQQRLVVFLDPSGDPLGSGYHILQSEIAIGAGGLWGRGIFQGTQTQLNFIPEQHTDFIFSALGEEW
GFLGAVVLLGLFFCLFARLLLIAQNSADDFGSLLTIGVFTMLLFQTVVNIGMTIGLAPVTGIPLPFVTFGRSFLITCFTA
IGLVESVALHRTKMVFPN
>Mature_418_residues
MELAKLSWNSWLNSLYKLFRGFDGWLLLFAVLLLSTGVLTIFSTRPEGIEWKAQLGTGLVGIAWALFLSRLTYGWLQRWS
WLIYSSACAMLLGVLFTGNSVKGAQRWIEFGGIQLQPSEFAKLGVIIALAALIQRYPIRSFGQIWVVLGVLAVPFLLVFK
QPDLGTALVFGAISLGMLYWGGARLGWLALVVSPLMAAILYAIWIPAWIVWVAAMAVVAWRELDWRWWGAIGAGAINLVA
GGLGQVFWHLLKPYQQQRLVVFLDPSGDPLGSGYHILQSEIAIGAGGLWGRGIFQGTQTQLNFIPEQHTDFIFSALGEEW
GFLGAVVLLGLFFCLFARLLLIAQNSADDFGSLLTIGVFTMLLFQTVVNIGMTIGLAPVTGIPLPFVTFGRSFLITCFTA
IGLVESVALHRTKMVFPN

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=362, Percent_Identity=35.0828729281768, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1786277, Length=347, Percent_Identity=32.2766570605187, Blast_Score=148, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45979; Mature: 45979

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELAKLSWNSWLNSLYKLFRGFDGWLLLFAVLLLSTGVLTIFSTRPEGIEWKAQLGTGLV
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHEEEECCCCCCEEHHHHCCCHH
GIAWALFLSRLTYGWLQRWSWLIYSSACAMLLGVLFTGNSVKGAQRWIEFGGIQLQPSEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEECHHHH
AKLGVIIALAALIQRYPIRSFGQIWVVLGVLAVPFLLVFKQPDLGTALVFGAISLGMLYW
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
GGARLGWLALVVSPLMAAILYAIWIPAWIVWVAAMAVVAWRELDWRWWGAIGAGAINLVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHH
GGLGQVFWHLLKPYQQQRLVVFLDPSGDPLGSGYHILQSEIAIGAGGLWGRGIFQGTQTQ
HHHHHHHHHHHCHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCHHCCCCCHH
LNFIPEQHTDFIFSALGEEWGFLGAVVLLGLFFCLFARLLLIAQNSADDFGSLLTIGVFT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
MLLFQTVVNIGMTIGLAPVTGIPLPFVTFGRSFLITCFTAIGLVESVALHRTKMVFPN
HHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MELAKLSWNSWLNSLYKLFRGFDGWLLLFAVLLLSTGVLTIFSTRPEGIEWKAQLGTGLV
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHEEEECCCCCCEEHHHHCCCHH
GIAWALFLSRLTYGWLQRWSWLIYSSACAMLLGVLFTGNSVKGAQRWIEFGGIQLQPSEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEECHHHH
AKLGVIIALAALIQRYPIRSFGQIWVVLGVLAVPFLLVFKQPDLGTALVFGAISLGMLYW
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
GGARLGWLALVVSPLMAAILYAIWIPAWIVWVAAMAVVAWRELDWRWWGAIGAGAINLVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHH
GGLGQVFWHLLKPYQQQRLVVFLDPSGDPLGSGYHILQSEIAIGAGGLWGRGIFQGTQTQ
HHHHHHHHHHHCHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCHHCCCCCHH
LNFIPEQHTDFIFSALGEEWGFLGAVVLLGLFFCLFARLLLIAQNSADDFGSLLTIGVFT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
MLLFQTVVNIGMTIGLAPVTGIPLPFVTFGRSFLITCFTAIGLVESVALHRTKMVFPN
HHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]