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The map label for this gene is pepQ [H]

Identifier: 34497909

GI number: 34497909

Start: 2639584

End: 2640795

Strand: Reverse

Name: pepQ [H]

Synonym: CV_2454

Alternate gene names: 34497909

Gene position: 2640795-2639584 (Counterclockwise)

Preceding gene: 34497910

Following gene: 34497908

Centisome position: 55.58

GC content: 65.51

Gene sequence:

>1212_bases
ATGGCGCATTTCGAGCAGGAACACCATCTGGAAATGGCGCGCCGCGACCAGCTGCTGCGCAGCCGCCTGCTGCAGGCCGG
CATCAGCCAGTATGTCGCCAGCGGCACGGAAAGCATTTATTACCTGTCCGGCATCAGCTATGAACCGCTGGAGCGCCCGT
TCTTCCTGCTGCTGGACGCCGCCAGCGGCAAGCGCAAGCTGCTGGTGCCCCAGCTCGAGCATGCGCACCTGAAGCAGGCC
TGGGGCGTGTCGGAAGACGACGTGCACAGCTACCGCGAATATCCGGCGCCGGCGGGGCAGCGCTGGGAGGATGCGCTGAT
CCCGCTGTTGAACGACCGTTTCGCCTTCGATCCCGCCGCGCCGCTGCATCTCGCCCAGTTCATGCAATCGGTGGGTGGAC
GCGCCGACGACGCGCTGGAGCGGATCCGCATGGTCAAGTCGCCTTGGGAGATCGCCAAGCTGGCGCGCGCGGGCCGTTAT
GCGGCGGAGGGTGTCAATCAGTTGCTGCGCGGCGTTTACGACGGCGTGTCGGTGGCGGAGGGCTTTGCCACCGGCCAGCA
GCTGCTTCGCCGGATCATACGGGACGAGCCGGCGTTCGATCCCCTGTGCACCCGGGTGCTGCTGGCGCCCTGGCCGGCGC
CGCTGAGCGCGCAGCCGCATGCGATTCCACAGCTGTCGCAAAGGCTGAAAAATGGCCCGCACGTGGTGATCTCCGTGGTG
CGTCTGGATGGCTACACCGCCGAATGCGAACGCACCTTCTTTACCCGTCCACCCACCGCCAGCCAGCGCGAGCGTTTTCA
GCTGATGAGCGAGGCGCGCAGACTGGCGATGTCCATGCTGAGGCCAGGCGCCGCCTGCGCCGAGATTGACGAGAAGGTCA
ACGATTTCCTGCGCGACGAAAGCTTCGGCGACTGGAGGCTGCGGCTGCACCGCTGCGGCCATGGTCTGGGCCTGGGCAAC
CATGAGGCGCCTTGGCTGGCCCTGGGCAGCGAGGACGTGCTGCAGGCCGGCATGGTGGTATCGATAGAGCCCGGCATTTA
CCTAGCGGACGAGGGCGGGTATCGCCACTCGGACACGCTGGCCATCACTGACGATGGCTGGAGCAATCTGACTGGCCAGG
CCGAGGTGGAATTGGATGCGCTGATTATCGCCGCCGCCAAGCCCACTCAGAGAATGAAGGGCTATTTCATTCGGAAACTG
GTCGCCGCTTAG

Upstream 100 bases:

>100_bases
AGTTGCGGGGACGTTCGCTTGCCGCGCAAGCATGATGCGGGGAAATGCGATTTGATTTATGTCATATTGATATCTCGGAT
CCTGGATTGGGGAAGACGAT

Downstream 100 bases:

>100_bases
CGCGGCTAAGCAAACCGCTGATCCAGCGTTGCGCCAACTTGCCGTACTGCTGGTACTGCCTGCGTCGGCACGGCTTGCTT
CAGCCGTAAAACAGAGTTTT

Product: X-Pro dipeptidase

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MAHFEQEHHLEMARRDQLLRSRLLQAGISQYVASGTESIYYLSGISYEPLERPFFLLLDAASGKRKLLVPQLEHAHLKQA
WGVSEDDVHSYREYPAPAGQRWEDALIPLLNDRFAFDPAAPLHLAQFMQSVGGRADDALERIRMVKSPWEIAKLARAGRY
AAEGVNQLLRGVYDGVSVAEGFATGQQLLRRIIRDEPAFDPLCTRVLLAPWPAPLSAQPHAIPQLSQRLKNGPHVVISVV
RLDGYTAECERTFFTRPPTASQRERFQLMSEARRLAMSMLRPGAACAEIDEKVNDFLRDESFGDWRLRLHRCGHGLGLGN
HEAPWLALGSEDVLQAGMVVSIEPGIYLADEGGYRHSDTLAITDDGWSNLTGQAEVELDALIIAAAKPTQRMKGYFIRKL
VAA

Sequences:

>Translated_403_residues
MAHFEQEHHLEMARRDQLLRSRLLQAGISQYVASGTESIYYLSGISYEPLERPFFLLLDAASGKRKLLVPQLEHAHLKQA
WGVSEDDVHSYREYPAPAGQRWEDALIPLLNDRFAFDPAAPLHLAQFMQSVGGRADDALERIRMVKSPWEIAKLARAGRY
AAEGVNQLLRGVYDGVSVAEGFATGQQLLRRIIRDEPAFDPLCTRVLLAPWPAPLSAQPHAIPQLSQRLKNGPHVVISVV
RLDGYTAECERTFFTRPPTASQRERFQLMSEARRLAMSMLRPGAACAEIDEKVNDFLRDESFGDWRLRLHRCGHGLGLGN
HEAPWLALGSEDVLQAGMVVSIEPGIYLADEGGYRHSDTLAITDDGWSNLTGQAEVELDALIIAAAKPTQRMKGYFIRKL
VAA
>Mature_402_residues
AHFEQEHHLEMARRDQLLRSRLLQAGISQYVASGTESIYYLSGISYEPLERPFFLLLDAASGKRKLLVPQLEHAHLKQAW
GVSEDDVHSYREYPAPAGQRWEDALIPLLNDRFAFDPAAPLHLAQFMQSVGGRADDALERIRMVKSPWEIAKLARAGRYA
AEGVNQLLRGVYDGVSVAEGFATGQQLLRRIIRDEPAFDPLCTRVLLAPWPAPLSAQPHAIPQLSQRLKNGPHVVISVVR
LDGYTAECERTFFTRPPTASQRERFQLMSEARRLAMSMLRPGAACAEIDEKVNDFLRDESFGDWRLRLHRCGHGLGLGNH
EAPWLALGSEDVLQAGMVVSIEPGIYLADEGGYRHSDTLAITDDGWSNLTGQAEVELDALIIAAAKPTQRMKGYFIRKLV
AA

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=231, Percent_Identity=26.8398268398268, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786364, Length=239, Percent_Identity=29.2887029288703, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 44997; Mature: 44866

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHFEQEHHLEMARRDQLLRSRLLQAGISQYVASGTESIYYLSGISYEPLERPFFLLLDA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEC
ASGKRKLLVPQLEHAHLKQAWGVSEDDVHSYREYPAPAGQRWEDALIPLLNDRFAFDPAA
CCCCCEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCC
PLHLAQFMQSVGGRADDALERIRMVKSPWEIAKLARAGRYAAEGVNQLLRGVYDGVSVAE
HHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
GFATGQQLLRRIIRDEPAFDPLCTRVLLAPWPAPLSAQPHAIPQLSQRLKNGPHVVISVV
HHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEE
RLDGYTAECERTFFTRPPTASQRERFQLMSEARRLAMSMLRPGAACAEIDEKVNDFLRDE
EECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
SFGDWRLRLHRCGHGLGLGNHEAPWLALGSEDVLQAGMVVSIEPGIYLADEGGYRHSDTL
CCCHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHHCCCEEEECCCEEEECCCCCCCCCEE
AITDDGWSNLTGQAEVELDALIIAAAKPTQRMKGYFIRKLVAA
EEECCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AHFEQEHHLEMARRDQLLRSRLLQAGISQYVASGTESIYYLSGISYEPLERPFFLLLDA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEC
ASGKRKLLVPQLEHAHLKQAWGVSEDDVHSYREYPAPAGQRWEDALIPLLNDRFAFDPAA
CCCCCEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCC
PLHLAQFMQSVGGRADDALERIRMVKSPWEIAKLARAGRYAAEGVNQLLRGVYDGVSVAE
HHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
GFATGQQLLRRIIRDEPAFDPLCTRVLLAPWPAPLSAQPHAIPQLSQRLKNGPHVVISVV
HHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEE
RLDGYTAECERTFFTRPPTASQRERFQLMSEARRLAMSMLRPGAACAEIDEKVNDFLRDE
EECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
SFGDWRLRLHRCGHGLGLGNHEAPWLALGSEDVLQAGMVVSIEPGIYLADEGGYRHSDTL
CCCHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHHCCCEEEECCCEEEECCCCCCCCCEE
AITDDGWSNLTGQAEVELDALIIAAAKPTQRMKGYFIRKLVAA
EEECCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]