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The map label for this gene is 33863296

Identifier: 33863296

GI number: 33863296

Start: 1101161

End: 1101547

Strand: Reverse

Name: 33863296

Synonym: PMT1025

Alternate gene names: NA

Gene position: 1101547-1101161 (Counterclockwise)

Preceding gene: 33863297

Following gene: 33863293

Centisome position: 45.69

GC content: 51.68

Gene sequence:

>387_bases
ATGACCATTCCTGTGCTTCCAGCCGTTGTCACCTTGGCTGCCGCGATCGTCTACCAAGGAACCATGTTTGCAGTGGCATT
TGCACGAAGCCAGCACAAAGTAAAAGCTCCAGCAACGAGTGGGCCAGAAGAATTTGAGCGAGTGCTACGTGTTCAGCAGA
ACACCCTTGAACAGATGATGTTCTTCCTGCCGGTGTTCTGGCTAGCAGCTCTTTCTAGCAACACGTCTGTTGCCTGCTTG
ATTGGCTTCATCTGGGTGGGCGCACGTATTGCTTATGGCATTGGCTATTGGAAAGCGGCCAAGCTGAGAGGGCCAGGCTT
TGCCATTAGCCTCCTTGCCAGCGCAGTTCTTCTGGTGATGGCAATTGTTGGTCTATTTAACTCATAG

Upstream 100 bases:

>100_bases
CAAACACTGCTCTTCATCAGAGAGGCACAGTCCCACTCGCTGGCCATCAAGGTTGGAATTCAGATGGCATCCTTAAAGTC
ATTGTGCTGATATCAATTTC

Downstream 100 bases:

>100_bases
TTGGCGATCTTATAGGAAGCTTCCCTCGGCAATAGTGGCCTTTTCTGCCAGAAGGCAACATTGTGAGCTTCGTTTGCAGA
TGCTGTGCACCTTGCGAATT

Product: MAPEG family protein

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MTIPVLPAVVTLAAAIVYQGTMFAVAFARSQHKVKAPATSGPEEFERVLRVQQNTLEQMMFFLPVFWLAALSSNTSVACL
IGFIWVGARIAYGIGYWKAAKLRGPGFAISLLASAVLLVMAIVGLFNS

Sequences:

>Translated_128_residues
MTIPVLPAVVTLAAAIVYQGTMFAVAFARSQHKVKAPATSGPEEFERVLRVQQNTLEQMMFFLPVFWLAALSSNTSVACL
IGFIWVGARIAYGIGYWKAAKLRGPGFAISLLASAVLLVMAIVGLFNS
>Mature_127_residues
TIPVLPAVVTLAAAIVYQGTMFAVAFARSQHKVKAPATSGPEEFERVLRVQQNTLEQMMFFLPVFWLAALSSNTSVACLI
GFIWVGARIAYGIGYWKAAKLRGPGFAISLLASAVLLVMAIVGLFNS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MAPEG family [H]

Homologues:

Organism=Homo sapiens, GI4505181, Length=108, Percent_Identity=39.8148148148148, Blast_Score=65, Evalue=1e-11,
Organism=Homo sapiens, GI22035629, Length=100, Percent_Identity=37, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001129 [H]

Pfam domain/function: PF01124 MAPEG [H]

EC number: 2.5.1.18

Molecular weight: Translated: 13779; Mature: 13647

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPVLPAVVTLAAAIVYQGTMFAVAFARSQHKVKAPATSGPEEFERVLRVQQNTLEQMM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
FFLPVFWLAALSSNTSVACLIGFIWVGARIAYGIGYWKAAKLRGPGFAISLLASAVLLVM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AIVGLFNS
HHHHHHCC
>Mature Secondary Structure 
TIPVLPAVVTLAAAIVYQGTMFAVAFARSQHKVKAPATSGPEEFERVLRVQQNTLEQMM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
FFLPVFWLAALSSNTSVACLIGFIWVGARIAYGIGYWKAAKLRGPGFAISLLASAVLLVM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AIVGLFNS
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]