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The map label for this gene is dnaJ2 [H]

Identifier: 33862976

GI number: 33862976

Start: 760553

End: 761455

Strand: Direct

Name: dnaJ2 [H]

Synonym: PMT0704

Alternate gene names: 33862976

Gene position: 760553-761455 (Clockwise)

Preceding gene: 33862975

Following gene: 33862977

Centisome position: 31.55

GC content: 53.05

Gene sequence:

>903_bases
ATGACTTCTACCGCTAAACCGGATTACTGGTCTTTGCTAGGTGTCTCTCCAGACAGTGACGCCTCCCAGCTCAAAAGGGC
ATTTCGTCGCGAAGCACGGCGATGGCATCCAGACCTCAATGGCAATGATTACCACGCCGAAGAACGCTTCAAATTGGTTA
ATGAGGCCTATGCAGTTCTCAGTGATCCAAGACGTCGGGCTGCTTGGCAGGGATCGATGTCGACAGAGCAAGCCATTACT
GATCCTTTCGCAGTTGGTTTTCCAACTTTCGATGAGTATCTGGAAGTGGTGCTCGGTTTGGAGCGCACAGACGAACAGCC
TGTTGACGTTGCTTACCCTTTCCCCTCAGAACATGTCGACTGGCCTGCGACGTCTCCACCACCACCTCCTCCTCCCGTAC
AGGCCAGTGATGATCTCGAGACGTTGGTCGAGTTGACCCCTGAGCAAGCCCTCTATGGGACTTCAGTGGATCTTGAGCTC
GATGACGGTACTCTTTTAGAGGTTGACACACCGCCTTTGGCTGGCGATGGCTGGCGGTTGCGTCTTGTGGGCGTAGCCCC
TGGAGGAAGGGACCACTTCCTTCAGTTGCGCGTTCAAACAGAAGACAGACTGAGGATTGACGGACTTCGTGTGCTTTATC
GCCTTGAGTTGTTTCCACCTGATGCAGCTCTTGGCTGTGCAGTGGATGTCCCAACTCTGTCTGGTCCTGTCACACTCCAA
GTGCCTCCAGCATCATCAAGTGGTCGTTTATTGCGCCTTCGCGGACGGGGACTTGAGCTTGATGGACGCAGAGGTGATCA
ATTGGTTGAAATTGTGGTGGTTATTCCTGCTGAACTTGCTGAAGCCGAACGTGCCCTCTACCGACGACTTCAAGAATTGG
CTCTTGATCCGGAAAATCTATAA

Upstream 100 bases:

>100_bases
TTCTCAGATGATGACTGGGATGAAGATCCTTGGAACAGCCCTGCCCGGTCGTCCGACGGCCGACGCATCTACAGGGGACG
TGAGCTAAATCCCTGGGACG

Downstream 100 bases:

>100_bases
AGCCGAATTAGATAATCGAGTGAGAGATCCCATCGGTCTGGCCTGATCCACATGCGCGTGTACGTCCTTCTCTATGACGC
CGGTAAAGACAACGAGGGTA

Product: DnaJ2 protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTSTAKPDYWSLLGVSPDSDASQLKRAFRREARRWHPDLNGNDYHAEERFKLVNEAYAVLSDPRRRAAWQGSMSTEQAIT
DPFAVGFPTFDEYLEVVLGLERTDEQPVDVAYPFPSEHVDWPATSPPPPPPPVQASDDLETLVELTPEQALYGTSVDLEL
DDGTLLEVDTPPLAGDGWRLRLVGVAPGGRDHFLQLRVQTEDRLRIDGLRVLYRLELFPPDAALGCAVDVPTLSGPVTLQ
VPPASSSGRLLRLRGRGLELDGRRGDQLVEIVVVIPAELAEAERALYRRLQELALDPENL

Sequences:

>Translated_300_residues
MTSTAKPDYWSLLGVSPDSDASQLKRAFRREARRWHPDLNGNDYHAEERFKLVNEAYAVLSDPRRRAAWQGSMSTEQAIT
DPFAVGFPTFDEYLEVVLGLERTDEQPVDVAYPFPSEHVDWPATSPPPPPPPVQASDDLETLVELTPEQALYGTSVDLEL
DDGTLLEVDTPPLAGDGWRLRLVGVAPGGRDHFLQLRVQTEDRLRIDGLRVLYRLELFPPDAALGCAVDVPTLSGPVTLQ
VPPASSSGRLLRLRGRGLELDGRRGDQLVEIVVVIPAELAEAERALYRRLQELALDPENL
>Mature_299_residues
TSTAKPDYWSLLGVSPDSDASQLKRAFRREARRWHPDLNGNDYHAEERFKLVNEAYAVLSDPRRRAAWQGSMSTEQAITD
PFAVGFPTFDEYLEVVLGLERTDEQPVDVAYPFPSEHVDWPATSPPPPPPPVQASDDLETLVELTPEQALYGTSVDLELD
DGTLLEVDTPPLAGDGWRLRLVGVAPGGRDHFLQLRVQTEDRLRIDGLRVLYRLELFPPDAALGCAVDVPTLSGPVTLQV
PPASSSGRLLRLRGRGLELDGRRGDQLVEIVVVIPAELAEAERALYRRLQELALDPENL

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Escherichia coli, GI1786197, Length=345, Percent_Identity=27.536231884058, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787235, Length=296, Percent_Identity=29.3918918918919, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17554644, Length=72, Percent_Identity=43.0555555555556, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C [H]

EC number: NA

Molecular weight: Translated: 33304; Mature: 33173

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTAKPDYWSLLGVSPDSDASQLKRAFRREARRWHPDLNGNDYHAEERFKLVNEAYAVL
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
SDPRRRAAWQGSMSTEQAITDPFAVGFPTFDEYLEVVLGLERTDEQPVDVAYPFPSEHVD
CCHHHHHHHCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCCCC
WPATSPPPPPPPVQASDDLETLVELTPEQALYGTSVDLELDDGTLLEVDTPPLAGDGWRL
CCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHCCCEEEEEECCCEEEEECCCCCCCCCEEE
RLVGVAPGGRDHFLQLRVQTEDRLRIDGLRVLYRLELFPPDAALGCAVDVPTLSGPVTLQ
EEEEECCCCCCEEEEEEECCCCCEEHHHEEEEEEEEECCCCCCCCEEEECCCCCCCEEEE
VPPASSSGRLLRLRGRGLELDGRRGDQLVEIVVVIPAELAEAERALYRRLQELALDPENL
ECCCCCCCCEEEEECCCCEECCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TSTAKPDYWSLLGVSPDSDASQLKRAFRREARRWHPDLNGNDYHAEERFKLVNEAYAVL
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
SDPRRRAAWQGSMSTEQAITDPFAVGFPTFDEYLEVVLGLERTDEQPVDVAYPFPSEHVD
CCHHHHHHHCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCCCC
WPATSPPPPPPPVQASDDLETLVELTPEQALYGTSVDLELDDGTLLEVDTPPLAGDGWRL
CCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHCCCEEEEEECCCEEEEECCCCCCCCCEEE
RLVGVAPGGRDHFLQLRVQTEDRLRIDGLRVLYRLELFPPDAALGCAVDVPTLSGPVTLQ
EEEEECCCCCCEEEEEEECCCCCEEHHHEEEEEEEEECCCCCCCCEEEECCCCCCCEEEE
VPPASSSGRLLRLRGRGLELDGRRGDQLVEIVVVIPAELAEAERALYRRLQELALDPENL
ECCCCCCCCEEEEECCCCEECCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9240461; 8003021; 7811295 [H]