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The map label for this gene is clpP1 [H]

Identifier: 33862948

GI number: 33862948

Start: 731207

End: 731800

Strand: Direct

Name: clpP1 [H]

Synonym: PMT0676

Alternate gene names: 33862948

Gene position: 731207-731800 (Clockwise)

Preceding gene: 33862946

Following gene: 33862952

Centisome position: 30.33

GC content: 46.13

Gene sequence:

>594_bases
ATGATCCCGATTGTGATTGAAGAGTCGGGCCGCGGGGAAAGGGCCTTCGATATTTATTCGCGCCTTTTGCGTGAACGGAT
CATCTTTCTTGGCGAGCCTGTGACAAGTGATTCGGCAAATCGAATTGTTGCTCAGATGTTGTTCTTGGAGGCGGAAGATC
CTGAAAAAGATATCTATTTGTATATCAATTCACCAGGAGGTTCAGTATATGATGGCCTCGGAATATTTGACACAATGCAG
CATGTCAAGCCAGATGTTCAAACAGTATGTGTAGGGCTTGCAGCAAGTATGGGAGCGTTCCTCCTCTGCGCTGGGGCAAT
GGGTAAACGCAGCAGTTTGCAACATTCTAGAATTATGATTCATCAGCCGCTTGGTGGTGCCAGAGGGCAAGCGAGTGATA
TTCGTATTCAGGCTGATGAGATTCTCTTCCTAAAGGATCGATTGAACCGAGTATTAGCAGATCGTACAGGTCAACCTCTA
GAGAGAATTCAAGAAGATACCGATCGAGATTTTTTCATGTCTCCCGCAGAAGCTGTTGGCTATGGACTTGTCGATAGTGT
GATCGATAAGCGTCCGGTTCATTCAGTCAATTGA

Upstream 100 bases:

>100_bases
AATGGTCTTTCGGTCACTCAAGTGCTTGGCCCGACCTTTTCGCACCTGACCATAGCGCTGCTACGGCGCCGTTAAGATCG
TGAAAACCGAGCAGAGCAGC

Downstream 100 bases:

>100_bases
CAAGGCTGCCTTGTGATAGGCAAGTATTGCAAGTCAAAAGAATTTCTAATAGATAGTTATCAATCCATTAATCCTGAAGG
AACTGATTGACTTGTTTGTA

Product: ATP-dependent Clp protease proteolytic subunit

Products: NA

Alternate protein names: Endopeptidase Clp 1 [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MIPIVIEESGRGERAFDIYSRLLRERIIFLGEPVTSDSANRIVAQMLFLEAEDPEKDIYLYINSPGGSVYDGLGIFDTMQ
HVKPDVQTVCVGLAASMGAFLLCAGAMGKRSSLQHSRIMIHQPLGGARGQASDIRIQADEILFLKDRLNRVLADRTGQPL
ERIQEDTDRDFFMSPAEAVGYGLVDSVIDKRPVHSVN

Sequences:

>Translated_197_residues
MIPIVIEESGRGERAFDIYSRLLRERIIFLGEPVTSDSANRIVAQMLFLEAEDPEKDIYLYINSPGGSVYDGLGIFDTMQ
HVKPDVQTVCVGLAASMGAFLLCAGAMGKRSSLQHSRIMIHQPLGGARGQASDIRIQADEILFLKDRLNRVLADRTGQPL
ERIQEDTDRDFFMSPAEAVGYGLVDSVIDKRPVHSVN
>Mature_197_residues
MIPIVIEESGRGERAFDIYSRLLRERIIFLGEPVTSDSANRIVAQMLFLEAEDPEKDIYLYINSPGGSVYDGLGIFDTMQ
HVKPDVQTVCVGLAASMGAFLLCAGAMGKRSSLQHSRIMIHQPLGGARGQASDIRIQADEILFLKDRLNRVLADRTGQPL
ERIQEDTDRDFFMSPAEAVGYGLVDSVIDKRPVHSVN

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=192, Percent_Identity=54.6875, Blast_Score=214, Evalue=3e-56,
Organism=Escherichia coli, GI1786641, Length=191, Percent_Identity=64.9214659685864, Blast_Score=258, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI17538017, Length=186, Percent_Identity=53.2258064516129, Blast_Score=201, Evalue=2e-52,
Organism=Drosophila melanogaster, GI20129427, Length=192, Percent_Identity=52.6041666666667, Blast_Score=209, Evalue=6e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 21808; Mature: 21808

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00381 CLP_PROTEASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPIVIEESGRGERAFDIYSRLLRERIIFLGEPVTSDSANRIVAQMLFLEAEDPEKDIYL
CCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEE
YINSPGGSVYDGLGIFDTMQHVKPDVQTVCVGLAASMGAFLLCAGAMGKRSSLQHSRIMI
EEECCCCCHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
HQPLGGARGQASDIRIQADEILFLKDRLNRVLADRTGQPLERIQEDTDRDFFMSPAEAVG
ECCCCCCCCCCCCEEEEHHHEEHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHH
YGLVDSVIDKRPVHSVN
HHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MIPIVIEESGRGERAFDIYSRLLRERIIFLGEPVTSDSANRIVAQMLFLEAEDPEKDIYL
CCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEE
YINSPGGSVYDGLGIFDTMQHVKPDVQTVCVGLAASMGAFLLCAGAMGKRSSLQHSRIMI
EEECCCCCHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
HQPLGGARGQASDIRIQADEILFLKDRLNRVLADRTGQPLERIQEDTDRDFFMSPAEAVG
ECCCCCCCCCCCCEEEEHHHEEHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHH
YGLVDSVIDKRPVHSVN
HHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA