Click here to switch to the map view.

The map label for this gene is lspA [H]

Identifier: 33862868

GI number: 33862868

Start: 651113

End: 651610

Strand: Direct

Name: lspA [H]

Synonym: PMT0595

Alternate gene names: 33862868

Gene position: 651113-651610 (Clockwise)

Preceding gene: 33862867

Following gene: 33862869

Centisome position: 27.01

GC content: 50.4

Gene sequence:

>498_bases
ATGAATCAACCTCAAATACTGAAGCAACGTCAACTATCACGTAGGGCAATGCTGCTAATCAGCATCCTGCTGATGCTGAT
TGATCAGATCAGCAAAAGCTGGGCCCGTCAACAACTCAGCTCAGGCTTGGTGCTCCCTTTTGTTCCTGGGCTATTGCAGT
TGCGTCTGATCAGCAATACAGGCGCAGCTTTTAATCTTTTCAATGGAGCAACATTCCTCTTAGGGCTGCTCAGCCTGGCT
GTGACCATTGGTTTGATGGTCTGGATTTGGAGAGCAGGACAGATGCCGATATGGCAAGGCCTTGCAATGTCCTTTCTGCT
CGGCGGAACGATCGGCAATGGCTTGGACCGATGGCGTCTAGGGCATGTCACCGACTTTCTGCAACTTGTACCGGTGGACT
TTCCGATTTTCAATGGAGCCGATGTGGCGATCAATTTGGCCGTGATCTGCTTCGGAATCGATGCCCTGATAAGACGCCAT
GGACAACAACACACCTAA

Upstream 100 bases:

>100_bases
TGCTATTTAGCTATACCTTTGGGCCCCTACCCGCTCAACTAGTCCTCTGTGCAGGCGTTGGCGTACTTGCCTTGCCATTG
CGAAATCTGCTGTTTGTTGA

Downstream 100 bases:

>100_bases
GCCTTGTGCCATGGCTGGAGTGATCATCAATTAGATCAGTCAACCCGATCGAAAAGTTGTTCTTTAAAGCGATAGCTGCC
GCTTTAGTGGAAACGTAAGG

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MNQPQILKQRQLSRRAMLLISILLMLIDQISKSWARQQLSSGLVLPFVPGLLQLRLISNTGAAFNLFNGATFLLGLLSLA
VTIGLMVWIWRAGQMPIWQGLAMSFLLGGTIGNGLDRWRLGHVTDFLQLVPVDFPIFNGADVAINLAVICFGIDALIRRH
GQQHT

Sequences:

>Translated_165_residues
MNQPQILKQRQLSRRAMLLISILLMLIDQISKSWARQQLSSGLVLPFVPGLLQLRLISNTGAAFNLFNGATFLLGLLSLA
VTIGLMVWIWRAGQMPIWQGLAMSFLLGGTIGNGLDRWRLGHVTDFLQLVPVDFPIFNGADVAINLAVICFGIDALIRRH
GQQHT
>Mature_165_residues
MNQPQILKQRQLSRRAMLLISILLMLIDQISKSWARQQLSSGLVLPFVPGLLQLRLISNTGAAFNLFNGATFLLGLLSLA
VTIGLMVWIWRAGQMPIWQGLAMSFLLGGTIGNGLDRWRLGHVTDFLQLVPVDFPIFNGADVAINLAVICFGIDALIRRH
GQQHT

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18272; Mature: 18272

Theoretical pI: Translated: 11.93; Mature: 11.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQPQILKQRQLSRRAMLLISILLMLIDQISKSWARQQLSSGLVLPFVPGLLQLRLISNT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
GAAFNLFNGATFLLGLLSLAVTIGLMVWIWRAGQMPIWQGLAMSFLLGGTIGNGLDRWRL
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHCCCHHHHHH
GHVTDFLQLVPVDFPIFNGADVAINLAVICFGIDALIRRHGQQHT
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNQPQILKQRQLSRRAMLLISILLMLIDQISKSWARQQLSSGLVLPFVPGLLQLRLISNT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
GAAFNLFNGATFLLGLLSLAVTIGLMVWIWRAGQMPIWQGLAMSFLLGGTIGNGLDRWRL
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHCCCHHHHHH
GHVTDFLQLVPVDFPIFNGADVAINLAVICFGIDALIRRHGQQHT
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12917641 [H]