BacMap

Definition	Shigella flexneri 2a str. 2457T, complete genome.
Accession	NC_004741
Length	4,599,354

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The map label for this gene is fabG

Identifier: 30065502

GI number: 30065502

Start: 4452843

End: 4453634

Strand: Direct

Name: fabG

Synonym: S4547

Alternate gene names: 30065502

Gene position: 4452843-4453634 (Clockwise)

Preceding gene: 30065500

Following gene: 30065503

Centisome position: 96.81

GC content: 54.04

Gene sequence:

>792_bases
ATGAAATCCACTCGTCCTGTTGCCGTGATTACCGGAGCCACTCGCGGTATTGGAAAGGGCTGTGCGCAGGAGCTTGCTCG
TGGCGGGTTTAACCTGCTGATTAACGATCGTCCCGATGCCGACAGCGTAGAAAAACTGCATATCACACAACAAGAATGTT
TGGCGGAAGGCGTGGAAGTGATTTGCTTCCCTGCTGATGTCGGTGATCTATCTCTGCATGAGGAGATGCTCGACGCGGCG
CAAAACCAGTGGGGGCGGCTGGACTGTCTGCTCAATAACGCGGGGATTTCAGTGAAAAAACGCGGTGACCTCCTCGACCT
CGAACCAGACAGCTTCGATCAAAACATTGCCATTAACACCCGCGCGCCGTTCTTCCTTGCTCAGGCATTCAGTAAGCGCT
TACTGGCACAGCCGAAACCGGAAGCGGAGCTGCCGCACCGCTCGATTATTTTCGTCAGTTCCATCAACGCCATCATGCTG
GCGATGAATCGCGGCGAATACACCATTGCCAAAACCGCCGTTTCTGCCGCTGCTCGTCTGTTTGCTGCTCGCCTTTGTAA
TGAACAAATTGGCGTTTATGAAGTGCGCCCTGGTCTCATCAAAACTGATATGACTATTCCGGCAACGGCTTATTACGACG
AACTGATTGCCAAAGGTCTGGTGCCGTGGGGACGTTGGGGTTATCCGGCTGATATTGCTTCCACCGTCCGCGCGATGGCG
GAAGGTAAACTGATTTACACCTGTGGTCAGGCGGTCGCAATCGACGGCGGCTTAAGTATGCCGCGCTTCTGA

Upstream 100 bases:

>100_bases
CGCCATCGCATATCAACCAACTAGATGGTTTATCTTTTTATCCTCCAGTCGCAAGCTAATCATCACCAAGGAAACAAAAT
TCAAAAAAGAGAGCTATTGT

Downstream 100 bases:

>100_bases
GGCTGAATCATGAGAGATCTGTTACAACGCCCGGATTTATTCAGTATCAATACCGCGACACTGGGCTATAAAACGCCGCT
ACCCGCCATTATTGATGCCT

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MKSTRPVAVITGATRGIGKGCAQELARGGFNLLINDRPDADSVEKLHITQQECLAEGVEVICFPADVGDLSLHEEMLDAA
QNQWGRLDCLLNNAGISVKKRGDLLDLEPDSFDQNIAINTRAPFFLAQAFSKRLLAQPKPEAELPHRSIIFVSSINAIML
AMNRGEYTIAKTAVSAAARLFAARLCNEQIGVYEVRPGLIKTDMTIPATAYYDELIAKGLVPWGRWGYPADIASTVRAMA
EGKLIYTCGQAVAIDGGLSMPRF

Sequences:

>Translated_263_residues
MKSTRPVAVITGATRGIGKGCAQELARGGFNLLINDRPDADSVEKLHITQQECLAEGVEVICFPADVGDLSLHEEMLDAA
QNQWGRLDCLLNNAGISVKKRGDLLDLEPDSFDQNIAINTRAPFFLAQAFSKRLLAQPKPEAELPHRSIIFVSSINAIML
AMNRGEYTIAKTAVSAAARLFAARLCNEQIGVYEVRPGLIKTDMTIPATAYYDELIAKGLVPWGRWGYPADIASTVRAMA
EGKLIYTCGQAVAIDGGLSMPRF
>Mature_263_residues
MKSTRPVAVITGATRGIGKGCAQELARGGFNLLINDRPDADSVEKLHITQQECLAEGVEVICFPADVGDLSLHEEMLDAA
QNQWGRLDCLLNNAGISVKKRGDLLDLEPDSFDQNIAINTRAPFFLAQAFSKRLLAQPKPEAELPHRSIIFVSSINAIML
AMNRGEYTIAKTAVSAAARLFAARLCNEQIGVYEVRPGLIKTDMTIPATAYYDELIAKGLVPWGRWGYPADIASTVRAMA
EGKLIYTCGQAVAIDGGLSMPRF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=28.8537549407115, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=31.1557788944724, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=27.4509803921569, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=26.0869565217391, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI40254992, Length=257, Percent_Identity=25.6809338521401, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=27.5193798449612, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=29.0196078431373, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788459, Length=262, Percent_Identity=29.0076335877863, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082100, Length=273, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787335, Length=257, Percent_Identity=27.6264591439689, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790717, Length=261, Percent_Identity=27.2030651340996, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789378, Length=255, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=26.4822134387352, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=271, Percent_Identity=31.3653136531365, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=30.8550185873606, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17551412, Length=274, Percent_Identity=28.1021897810219, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=29.2592592592593, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=275, Percent_Identity=28, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=31.2267657992565, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=27.037037037037, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=275, Percent_Identity=30.5454545454545, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=266, Percent_Identity=27.0676691729323, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=29.8892988929889, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=260, Percent_Identity=25, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=29.0076335877863, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25147288, Length=257, Percent_Identity=30.3501945525292, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=26.6409266409266, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=275, Percent_Identity=30.1818181818182, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=28.1954887218045, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=29.0566037735849, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=267, Percent_Identity=26.5917602996255, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=275, Percent_Identity=28.7272727272727, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=275, Percent_Identity=26.9090909090909, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=27.3408239700375, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=273, Percent_Identity=26.3736263736264, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=266, Percent_Identity=25.187969924812, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=26.7175572519084, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=25.9842519685039, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=259, Percent_Identity=25.8687258687259, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI23397609, Length=262, Percent_Identity=27.4809160305344, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=28.4046692607004, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=27.34375, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=25.968992248062, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=26.0700389105058, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21358495, Length=227, Percent_Identity=27.7533039647577, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=27.6264591439689, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=28.2945736434109, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28552; Mature: 28552

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTRPVAVITGATRGIGKGCAQELARGGFNLLINDRPDADSVEKLHITQQECLAEGVEV
CCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCCHHHHHHCCCEE
ICFPADVGDLSLHEEMLDAAQNQWGRLDCLLNNAGISVKKRGDLLDLEPDSFDQNIAINT
EEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEECCCCEEECCCCCCCCCEEEEC
RAPFFLAQAFSKRLLAQPKPEAELPHRSIIFVSSINAIMLAMNRGEYTIAKTAVSAAARL
CCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEHHHHHHHHHHHH
FAARLCNEQIGVYEVRPGLIKTDMTIPATAYYDELIAKGLVPWGRWGYPADIASTVRAMA
HHHHHHCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
EGKLIYTCGQAVAIDGGLSMPRF
CCCEEEECCCEEEECCCCCCCCC
>Mature Secondary Structure
MKSTRPVAVITGATRGIGKGCAQELARGGFNLLINDRPDADSVEKLHITQQECLAEGVEV
CCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCCHHHHHHCCCEE
ICFPADVGDLSLHEEMLDAAQNQWGRLDCLLNNAGISVKKRGDLLDLEPDSFDQNIAINT
EEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEECCCCEEECCCCCCCCCEEEEC
RAPFFLAQAFSKRLLAQPKPEAELPHRSIIFVSSINAIMLAMNRGEYTIAKTAVSAAARL
CCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEHHHHHHHHHHHH
FAARLCNEQIGVYEVRPGLIKTDMTIPATAYYDELIAKGLVPWGRWGYPADIASTVRAMA
HHHHHHCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
EGKLIYTCGQAVAIDGGLSMPRF
CCCEEEECCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA