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The map label for this gene is deoR [H]

Identifier: 30065439

GI number: 30065439

Start: 4380959

End: 4381654

Strand: Direct

Name: deoR [H]

Synonym: S4473

Alternate gene names: 30065439

Gene position: 4380959-4381654 (Clockwise)

Preceding gene: 30065436

Following gene: 30065441

Centisome position: 95.25

GC content: 45.98

Gene sequence:

>696_bases
ATGCTGGAAGTTTCTGTAATGACTATTCGTCGCGATCTCCATCAGGAAGATGAACCTCTGCCACTGACCCTACTGGGTGG
CTATATTGTAATGGTGAATAAACCCGCGCCATCCATGCCAGTAATCCATGACGTTCCAAAAAATCATCGTGATGACTTAC
CTATTGCAATTCTGGCTGCCGGAATGGTTAATGAAAATGATCTGATCTTCTTTGATAATGGCCAGGAGATACCACTCGTT
ATAAGCATGATCCCGGATGCAATCACCTTCACCGGCATCTGTTACTCACATCGCGTCTTTGTTGCGTTGAATGAAAAGCC
TAATGTAACAGCAATACTTTGTGGTGGTACGTATCGTGCCAGAAGTGATGCTTTTTACGATGCCAGTAACTCTTCGCCAT
TAGACTCTCTCAATCCGCGAAAAATATTTATTTCCGCCAGCGGTGTGCATAATCACTTTGGCGTCAGCTGGTTTAACCCT
GAAGATCTTGCCACTAAGCGTAAAGTGATGAACCGTGGACTACGGAAAATTTTGCTCGCCCGCCACGCGTTGTTCGATGA
AGTGGCCTCTGCCAGCCTCGCACCGATCTCTGCATTTGACGTTCTGATTAGCGATCGTCCGTTACCGGCAGATTATGTTA
CGCACTGCCAGAATGGTTCTGTAAAGATCATTACACCTGATTCAGAAGACGAATGA

Upstream 100 bases:

>100_bases
AGCCACGCAAGCACCTTAAAATCACCATCATACACTAAATCAGTAAGTTGGCAGCATTACCAAGAAAACCGACAGAATCC
ATTTGAAAGACGCAGCGCGA

Downstream 100 bases:

>100_bases
CTTACTGAAAAAACACCACAATCTTGTTAAACATCGTCGGGTTGGACTGATTACGTTGCACTTTCACCACATATTCCAGC
TTATCTATTTGGCTTATCAC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MLEVSVMTIRRDLHQEDEPLPLTLLGGYIVMVNKPAPSMPVIHDVPKNHRDDLPIAILAAGMVNENDLIFFDNGQEIPLV
ISMIPDAITFTGICYSHRVFVALNEKPNVTAILCGGTYRARSDAFYDASNSSPLDSLNPRKIFISASGVHNHFGVSWFNP
EDLATKRKVMNRGLRKILLARHALFDEVASASLAPISAFDVLISDRPLPADYVTHCQNGSVKIITPDSEDE

Sequences:

>Translated_231_residues
MLEVSVMTIRRDLHQEDEPLPLTLLGGYIVMVNKPAPSMPVIHDVPKNHRDDLPIAILAAGMVNENDLIFFDNGQEIPLV
ISMIPDAITFTGICYSHRVFVALNEKPNVTAILCGGTYRARSDAFYDASNSSPLDSLNPRKIFISASGVHNHFGVSWFNP
EDLATKRKVMNRGLRKILLARHALFDEVASASLAPISAFDVLISDRPLPADYVTHCQNGSVKIITPDSEDE
>Mature_231_residues
MLEVSVMTIRRDLHQEDEPLPLTLLGGYIVMVNKPAPSMPVIHDVPKNHRDDLPIAILAAGMVNENDLIFFDNGQEIPLV
ISMIPDAITFTGICYSHRVFVALNEKPNVTAILCGGTYRARSDAFYDASNSSPLDSLNPRKIFISASGVHNHFGVSWFNP
EDLATKRKVMNRGLRKILLARHALFDEVASASLAPISAFDVLISDRPLPADYVTHCQNGSVKIITPDSEDE

Specific function: This protein is one of the repressors that regulate the expression of deoCABD genes, which encode nucleotide and deoxy ribonucleotide catabolizing enzymes. It also negatively regulates the expression of nupG (a transport protein) and tsx (a pore- forming

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787063, Length=224, Percent_Identity=34.8214285714286, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790753, Length=226, Percent_Identity=23.4513274336283, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 25478; Mature: 25478

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEVSVMTIRRDLHQEDEPLPLTLLGGYIVMVNKPAPSMPVIHDVPKNHRDDLPIAILAA
CEEEEHHHHHHHHCCCCCCCCEEEECCEEEEECCCCCCCCEEECCCCCCCCCCCEEEEEE
GMVNENDLIFFDNGQEIPLVISMIPDAITFTGICYSHRVFVALNEKPNVTAILCGGTYRA
CCCCCCCEEEEECCCCCCEEEEECCCHHHHEEEEEEEEEEEEECCCCCEEEEEECCCCCC
RSDAFYDASNSSPLDSLNPRKIFISASGVHNHFGVSWFNPEDLATKRKVMNRGLRKILLA
CCCCEEECCCCCCCCCCCCCEEEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHH
RHALFDEVASASLAPISAFDVLISDRPLPADYVTHCQNGSVKIITPDSEDE
HHHHHHHHHHCCCCCHHHEEEEECCCCCCHHHHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure
MLEVSVMTIRRDLHQEDEPLPLTLLGGYIVMVNKPAPSMPVIHDVPKNHRDDLPIAILAA
CEEEEHHHHHHHHCCCCCCCCEEEECCEEEEECCCCCCCCEEECCCCCCCCCCCEEEEEE
GMVNENDLIFFDNGQEIPLVISMIPDAITFTGICYSHRVFVALNEKPNVTAILCGGTYRA
CCCCCCCEEEEECCCCCCEEEEECCCHHHHEEEEEEEEEEEEECCCCCEEEEEECCCCCC
RSDAFYDASNSSPLDSLNPRKIFISASGVHNHFGVSWFNPEDLATKRKVMNRGLRKILLA
CCCCEEECCCCCCCCCCCCCEEEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHH
RHALFDEVASASLAPISAFDVLISDRPLPADYVTHCQNGSVKIITPDSEDE
HHHHHHHHHHCCCCCHHHEEEEECCCCCCHHHHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]