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The map label for this gene is dppC

Identifier: 30065178

GI number: 30065178

Start: 4099226

End: 4100128

Strand: Direct

Name: dppC

Synonym: S4193

Alternate gene names: 30065178

Gene position: 4099226-4100128 (Clockwise)

Preceding gene: 30065177

Following gene: 30065179

Centisome position: 89.13

GC content: 58.91

Gene sequence:

>903_bases
ATGTCACAGGTTACTGAAAATAAAGTGATTAGCGCACCGGTGCCGATGACCCCGTTACAGGAGTTCTGGCACTATTTTAA
ACGCAACAAAGGCGCGGTCGTCGGGCTGGTTTACGTCGCCATCGTGCTGTTCATCGCGATCTTTGCCAACTGGATTGCGC
CTTATAACCCGGCGGATCAGTTCCGCGATGCGCTGCTCGCCCCGCCAGCCTGGCAGGAAGGCGGCAGTATGGCACACTTG
CTGGGCACCGATGACGTCGGTCGTGATGTGCTGTCGCGGCTGATGTACGGCGCGCGTTTATCGCTGCTGGTTGGCTGTCT
GGTGGTGGTGTTGTCGCTGATTATGGGCGTTATTCTCGGCCTGATCGCCGGTTACTTCGGCGGCCTGGTTGATAACATTA
TCATGCGCGTGGTCGATATCATGCTGGCGCTGCCAAGTCTGCTGTTGGCACTGGTGCTGGTGGCGATTTTCGGCCCGTCG
ATTGGTAACGCCGCGCTGGCGCTGACCTTCGTTGCCTTGCCGCACTATGTGCGCTTAACCCGCGCCGCCGTGCTGGTGGA
GGTGAATCGCGATTACGTCACCGCCTCTCGCGTGGCAGGTGCCGGGGCGATGCGCCAGATGTTTATTAACATCTTCCCGA
ACTGCCTTGCGCCGCTGATTGTTCAGGCGTCGCTCGGTTTCTCTAACGCCATTCTCGATATGGCTGCTCTTGGTTTCCTC
GGCATGGGGGCACAGCCGCCAACGCCTGAGTGGGGCACCATGCTCTCCGACGTGTTGCAGTTCGCGCAAAGCGCCTGGTG
GGTCGTGACCTTCCCTGGTCTGGCGATCCTGTTGACGGTGCTGGCATTTAACCTGATGGGTGACGGTCTGCGTGACGCGC
TCGATCCCAAACTAAAGCAGTAA

Upstream 100 bases:

>100_bases
ATTGCTGGTGGCGACGATGATTATCCTCGTCAACTTGCTGGTCGATCTGCTGTACGGCGTGGTGAACCCGCGTATTCGTC
ATAAGAAGTAAGGGGACATC

Downstream 100 bases:

>100_bases
GAGGTTCGAGATGGCGTTATTAAATGTAGATAAATTATCGGTGCATTTCGGCGACGAAAGCGCACCGTTCCGCGCCGTAG
ACCGCATCAGCTACAGCGTA

Product: dipeptide transporter

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVAIVLFIAIFANWIAPYNPADQFRDALLAPPAWQEGGSMAHL
LGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS
IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFL
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ

Sequences:

>Translated_300_residues
MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVAIVLFIAIFANWIAPYNPADQFRDALLAPPAWQEGGSMAHL
LGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS
IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFL
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ
>Mature_299_residues
SQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVAIVLFIAIFANWIAPYNPADQFRDALLAPPAWQEGGSMAHLL
GTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSI
GNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFLG
MGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=300, Percent_Identity=99.3333333333333, Blast_Score=592, Evalue=1e-170,
Organism=Escherichia coli, GI1787054, Length=283, Percent_Identity=41.696113074205, Blast_Score=232, Evalue=2e-62,
Organism=Escherichia coli, GI1787760, Length=265, Percent_Identity=45.6603773584906, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1787549, Length=288, Percent_Identity=41.3194444444444, Blast_Score=214, Evalue=5e-57,
Organism=Escherichia coli, GI1789889, Length=252, Percent_Identity=37.6984126984127, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787498, Length=297, Percent_Identity=31.986531986532, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1788505, Length=223, Percent_Identity=30.9417040358744, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32267; Mature: 32136

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVAIVLFIAIFANWIAPYNPADQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHH
FRDALLAPPAWQEGGSMAHLLGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVILG
HHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIGNAALALTFVALPHYVRLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
RAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFL
HHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ
CCCCCCCCCHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
>Mature Secondary Structure 
SQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVAIVLFIAIFANWIAPYNPADQ
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHH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PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]