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The map label for this gene is phoU

Identifier: 30065039

GI number: 30065039

Start: 3934224

End: 3934949

Strand: Reverse

Name: phoU

Synonym: S4041

Alternate gene names: 30065039

Gene position: 3934949-3934224 (Counterclockwise)

Preceding gene: 30065040

Following gene: 30065038

Centisome position: 85.55

GC content: 52.2

Gene sequence:

>726_bases
ATGGACAGTCTCAATCTTAATAAACATATTTCCGGCCAGTTCAACGCCGAACTGGAAAGTATCCGCACGCAGGTGATGAC
CATGGGCGGCATGGTGGAGCAGCAGCTTTCTGATGCAATCACCGCGATGCATAACCAGGACAGCGATCTGGCGAAGCGCG
TGATCGAAGGCGACAAGAACGTCAACATGATGGAAGTGGCGATCGATGAAGCCTGCGTGCGCATTATCGCCAAACGTCAG
CCGACGGCGAGCGACCTGCGACTGGTTATGGTGATCAGTAAAACCATTGCCGAGCTGGAGCGTATTGGCGACGTGGCGGA
CAAAATCTGCCGTACTGCGCTGGAGAAATTCTCCCAGCAGCATCAGCCGTTGCTGGTAAGTCTGGAGTCGCTGGGCCGTC
ATACCATCCAGATGCTGCACGACGTGCTGGACGCGTTCGCGCGGATGGACATTGACGAAGCGGTACGTATTTATCGTGAA
GATAAAAAAGTCGATCAGGAATACGAAGGTATTGTTCGTCAACTGATGACCTACATGATGGAAGATTCGCGCACTATTCC
GAGCGTACTTACCGCGCTGTTCTGTGCGCGTTCAATCGAACGTATCGGCGACCGCTGCCAGAATATTTGTGAGTTTATCT
TCTACTACGTGAAGGGTCAGGATTTCCGTCATGTAGGCGGTGATGAGCTGGATAAACTGCTGGCGGGAAAAGATAGCGAC
AAATAA

Upstream 100 bases:

>100_bases
TGATTGAGTTCAGCAACACGGACGATCTGTTCACCAAGCCAGCGAAGAAACAAACAGAAGACTACATCACCGGTCGTTAC
GGTTGATTCAGGAGTGCGTT

Downstream 100 bases:

>100_bases
TTCACCAGACAAATCCCAATAACTTAATTATTGGGATTTGTTATATATAACTTTATAAATTCCTAAAATTACACAAAGTT
AATAACTGCGAGCATGGTCA

Product: transcriptional regulator PhoU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMHNQDSDLAKRVIEGDKNVNMMEVAIDEACVRIIAKRQ
PTASDLRLVMVISKTIAELERIGDVADKICRTALEKFSQQHQPLLVSLESLGRHTIQMLHDVLDAFARMDIDEAVRIYRE
DKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNICEFIFYYVKGQDFRHVGGDELDKLLAGKDSD
K

Sequences:

>Translated_241_residues
MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMHNQDSDLAKRVIEGDKNVNMMEVAIDEACVRIIAKRQ
PTASDLRLVMVISKTIAELERIGDVADKICRTALEKFSQQHQPLLVSLESLGRHTIQMLHDVLDAFARMDIDEAVRIYRE
DKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNICEFIFYYVKGQDFRHVGGDELDKLLAGKDSD
K
>Mature_241_residues
MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMHNQDSDLAKRVIEGDKNVNMMEVAIDEACVRIIAKRQ
PTASDLRLVMVISKTIAELERIGDVADKICRTALEKFSQQHQPLLVSLESLGRHTIQMLHDVLDAFARMDIDEAVRIYRE
DKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNICEFIFYYVKGQDFRHVGGDELDKLLAGKDSD
K

Specific function: Probably involved in phosphate transport and/or metabolism

COG id: COG0704

COG function: function code P; Phosphate uptake regulator

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phoU family

Homologues:

Organism=Escherichia coli, GI1790161, Length=241, Percent_Identity=100, Blast_Score=495, Evalue=1e-141,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHOU_ECOLI (P0A9K7)

Other databases:

- EMBL:   X02723
- EMBL:   K01992
- EMBL:   L10328
- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   M16487
- PIR:   D23311
- RefSeq:   AP_004063.1
- RefSeq:   NP_418180.1
- ProteinModelPortal:   P0A9K7
- SMR:   P0A9K7
- IntAct:   P0A9K7
- STRING:   P0A9K7
- EnsemblBacteria:   EBESCT00000003052
- EnsemblBacteria:   EBESCT00000016462
- GeneID:   948233
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW3702
- KEGG:   eco:b3724
- EchoBASE:   EB0728
- EcoGene:   EG10735
- eggNOG:   COG0704
- GeneTree:   EBGT00050000009094
- HOGENOM:   HBG725662
- OMA:   VAIDEEC
- ProtClustDB:   PRK11115
- BioCyc:   EcoCyc:EG10735-MONOMER
- Genevestigator:   P0A9K7
- GO:   GO:0005737
- InterPro:   IPR008170
- TIGRFAMs:   TIGR02135

Pfam domain/function: PF01895 PhoU

EC number: NA

Molecular weight: Translated: 27418; Mature: 27418

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMHNQDSDLAKRVIEGDKN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
VNMMEVAIDEACVRIIAKRQPTASDLRLVMVISKTIAELERIGDVADKICRTALEKFSQQ
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQPLLVSLESLGRHTIQMLHDVLDAFARMDIDEAVRIYREDKKVDQEYEGIVRQLMTYMM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDSRTIPSVLTALFCARSIERIGDRCQNICEFIFYYVKGQDFRHVGGDELDKLLAGKDSD
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCC
K
C
>Mature Secondary Structure
MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMHNQDSDLAKRVIEGDKN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
VNMMEVAIDEACVRIIAKRQPTASDLRLVMVISKTIAELERIGDVADKICRTALEKFSQQ
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQPLLVSLESLGRHTIQMLHDVLDAFARMDIDEAVRIYREDKKVDQEYEGIVRQLMTYMM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDSRTIPSVLTALFCARSIERIGDRCQNICEFIFYYVKGQDFRHVGGDELDKLLAGKDSD
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2993631; 3881386; 7686882; 9278503; 3034860; 3536855; 8226621