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The map label for this gene is yieG

Identifier: 30065025

GI number: 30065025

Start: 3919150

End: 3920487

Strand: Reverse

Name: yieG

Synonym: S4026

Alternate gene names: 30065025

Gene position: 3920487-3919150 (Counterclockwise)

Preceding gene: 30065031

Following gene: 30065022

Centisome position: 85.24

GC content: 52.47

Gene sequence:

>1338_bases
ATGAGTCATCAACATACCACCCAGACTTCTGGTCAGAGGATGCTGGAACGTGTTTTTAAACTGCGCGAACATGGTACTAC
GGCACGAACTGAAGTGATTGCCGGGTTCACCACCTTCCTGACGATGGTCTACATCGTATTTGTTAACCCACAAATTCTGG
GCGTTGCTGGCATGGACACCAGTGCCGTCTTCGTAACAACCTGTCTGATTGCTGCTTTCGGTAGCATTATGATGGGATTG
TTTGCAAACCTTCCGGTGGCGCTGGCTCCTGCGATGGGGCTTAACGCCTTTTTCGCTTTTGTGGTTGTCCAGGCAATGGG
GCTGCCGTGGCAGATCGGTATGGGCGCAATCTTCTGGGGCGCTGTCGGACTGCTTCTTTTGACCATTTTCCGCGTTCGTT
ACTGGATGATTGCTAACATTCCGGTAAGTCTGCGTGTGGGTATTACCAGCGGTATCGGCCTGTTTATCGGCATGATGGGG
CTGAAAAACGCAGGTGTGATTGTCGCTAACTCGGAAACGCTGGTGAGCATCGGTAATCTGACTTCTCACAGCGTACTTCT
GGGTATCCTCGGCTTTTTCATCATTGCTATTCTGGCCTCGCGCAACATTCACGCAGCGGTGCTGGTTTCTATCGTGGTGA
CGACGCTGCTGGGCTGGATGCTGGGTGATGTGCACTACAATGGCATCGTTTCTGCGCCGCCGAGCGTAATGACAGTTGTG
GGTCATGTAGATTTAGCCGGGTCGTTTAACCTCGGGCTGGCAGGGGTGATTTTCTCTTTCATGTTGGTCAACTTGTTTGA
CTCCTCCGGTACGCTGATTGGCGTGACCGATAAAGCAGGTCTGGCGGATGAGAAGGGGAAATTCCCGCGCATGAAGCAGG
CGCTGTATGTCGACAGTATCTCTTCCGTGACCGGTTCGTTTATCGGTACTTCTTCCGTTACGGCTTATATTGAGTCCTCT
TCCGGCGTATCGGTTGGCGGTCGTACCGGTCTGACGGCAGTGGTTGTTGGTCTGCTGTTCCTGCTGGTTATCTTTCTGTC
GCCGCTGGCGGGAATGGTGCCAGACTACGCTGCAGCTGGCGCGTTGATCTACGTTGGCGTGTTGATGACCTCAAGTCTTG
CTCGCGTGAACTGGCAGGATCTTACTGAATCTGTTCCGGCGTTTATTACCGCCGTGATGATGCCGTTCAGCTTTTCGATT
ACCGAAGGTATTGCGCTGGGCTTTATCTCCTACTGCGTGATGAAGATTGGTACCGGGCGTCTGCGTGACCTTAGCCCGTG
CGTAATCATCGTTGCGCTGCTGTTTATCCTGAAGATTGTATTTATCGACGCTCATTAA

Upstream 100 bases:

>100_bases
TATAAGTAAATCCAATAAAAAAGTCTCTCACAAACGCGCCTATTGTCGCATTTTGGTATACGATAGCGACGGATTTTCCC
TCCTTGTTCGGAAATAGATA

Downstream 100 bases:

>100_bases
AATCGATAGCGCATTAAAAACCCGCCATGCATGATTACTGGCGGGTTTTTTATTTAGATCTTAACTCGCTGAATAAACTC
ACCAAATGCGGTCAATTGCC

Product: putative membrane / transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSHQHTTQTSGQRMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDTSAVFVTTCLIAAFGSIMMGL
FANLPVALAPAMGLNAFFAFVVVQAMGLPWQIGMGAIFWGAVGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMG
LKNAGVIVANSETLVSIGNLTSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLGWMLGDVHYNGIVSAPPSVMTVV
GHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADEKGKFPRMKQALYVDSISSVTGSFIGTSSVTAYIESS
SGVSVGGRTGLTAVVVGLLFLLVIFLSPLAGMVPDYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAVMMPFSFSI
TEGIALGFISYCVMKIGTGRLRDLSPCVIIVALLFILKIVFIDAH

Sequences:

>Translated_445_residues
MSHQHTTQTSGQRMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDTSAVFVTTCLIAAFGSIMMGL
FANLPVALAPAMGLNAFFAFVVVQAMGLPWQIGMGAIFWGAVGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMG
LKNAGVIVANSETLVSIGNLTSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLGWMLGDVHYNGIVSAPPSVMTVV
GHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADEKGKFPRMKQALYVDSISSVTGSFIGTSSVTAYIESS
SGVSVGGRTGLTAVVVGLLFLLVIFLSPLAGMVPDYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAVMMPFSFSI
TEGIALGFISYCVMKIGTGRLRDLSPCVIIVALLFILKIVFIDAH
>Mature_444_residues
SHQHTTQTSGQRMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDTSAVFVTTCLIAAFGSIMMGLF
ANLPVALAPAMGLNAFFAFVVVQAMGLPWQIGMGAIFWGAVGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMGL
KNAGVIVANSETLVSIGNLTSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLGWMLGDVHYNGIVSAPPSVMTVVG
HVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADEKGKFPRMKQALYVDSISSVTGSFIGTSSVTAYIESSS
GVSVGGRTGLTAVVVGLLFLLVIFLSPLAGMVPDYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAVMMPFSFSIT
EGIALGFISYCVMKIGTGRLRDLSPCVIIVALLFILKIVFIDAH

Specific function: High-affinity uptake of adenine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=445, Percent_Identity=98.876404494382, Blast_Score=866, Evalue=0.0,
Organism=Escherichia coli, GI87082309, Length=444, Percent_Identity=74.0990990990991, Blast_Score=660, Evalue=0.0,
Organism=Escherichia coli, GI1790499, Length=438, Percent_Identity=34.703196347032, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI48994909, Length=435, Percent_Identity=35.1724137931034, Blast_Score=248, Evalue=6e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47014; Mature: 46882

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00267 TACHYKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHQHTTQTSGQRMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDT
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
SAVFVTTCLIAAFGSIMMGLFANLPVALAPAMGLNAFFAFVVVQAMGLPWQIGMGAIFWG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AVGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMGLKNAGVIVANSETLVSIGNL
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCEEEECCCCEEEECCC
TSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLGWMLGDVHYNGIVSAPPSVMTVV
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHE
GHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADEKGKFPRMKQALYVDSI
ECEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHH
SSVTGSFIGTSSVTAYIESSSGVSVGGRTGLTAVVVGLLFLLVIFLSPLAGMVPDYAAAG
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ALIYVGVLMTSSLARVNWQDLTESVPAFITAVMMPFSFSITEGIALGFISYCVMKIGTGR
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
LRDLSPCVIIVALLFILKIVFIDAH
CCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SHQHTTQTSGQRMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDT
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
SAVFVTTCLIAAFGSIMMGLFANLPVALAPAMGLNAFFAFVVVQAMGLPWQIGMGAIFWG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AVGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMGLKNAGVIVANSETLVSIGNL
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCEEEECCCCEEEECCC
TSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLGWMLGDVHYNGIVSAPPSVMTVV
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHE
GHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADEKGKFPRMKQALYVDSI
ECEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHH
SSVTGSFIGTSSVTAYIESSSGVSVGGRTGLTAVVVGLLFLLVIFLSPLAGMVPDYAAAG
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ALIYVGVLMTSSLARVNWQDLTESVPAFITAVMMPFSFSITEGIALGFISYCVMKIGTGR
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
LRDLSPCVIIVALLFILKIVFIDAH
CCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]