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The map label for this gene is xdhC [H]

Identifier: 30064197

GI number: 30064197

Start: 2955582

End: 2956061

Strand: Direct

Name: xdhC [H]

Synonym: S3070

Alternate gene names: 30064197

Gene position: 2955582-2956061 (Clockwise)

Preceding gene: 30064196

Following gene: 30064198

Centisome position: 64.26

GC content: 52.08

Gene sequence:

>480_bases
ATGAATCACAGCGAAACAATTACCACCGAATGCACCATTAACGGGATGCCTTTTCAGCTTCACGCCGCACCAGGCACGCC
GCTCTCGGAATTACTCCGCGAACAAGGACTGCTAAGTGTCAAACAAGGGTGCTGCGTGGGTGAATGTGGTGCCTGTACGG
TGTTGGTCGACGGCACAGCAATAGACAGTTGCTTATACCTTGCCGCCTGGGCTGAAGGAAAAGAGATCCGCACGCTGGAA
GGTGAAGCGAAAGGCGGAAAACTTTCTCATGTTCAGCAGGCTTATGCGAAATCCGGCACAGTGCAGTGCGGGTTTTGTAC
GCCTGGCCTGATTATGGCTACCACGGCAATGCTGGCGAAACCACGCGAGAAGCCATTAACCATTACGGAAATTCGTCGCG
GACTGGCGGGAAATCTTTGTCGCTGCACGGGGTATCAGATGATTGTAAATACAGTTCTGGATTGCGAGAAAACGAAGTAA

Upstream 100 bases:

>100_bases
CTTCATGGCGGGCCAGTAAAGAGTTTCGTCTGCATCTCATCCAGACGATGACCAAAAAAGTGATTAGCGAAGCCGTCGCC
GCGGCGGGGGGAAAATTGCA

Downstream 100 bases:

>100_bases
AAGGATATCCGGCCTGAATTCAGGCCGGATTCACTGAGGTTATGTGTTTAACAACTCGGTAATGCTGCCAACTTACTGAT
TTAGTGTATGATGGTGATTT

Product: xanthine dehydrogenase subunit XdhC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MNHSETITTECTINGMPFQLHAAPGTPLSELLREQGLLSVKQGCCVGECGACTVLVDGTAIDSCLYLAAWAEGKEIRTLE
GEAKGGKLSHVQQAYAKSGTVQCGFCTPGLIMATTAMLAKPREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK

Sequences:

>Translated_159_residues
MNHSETITTECTINGMPFQLHAAPGTPLSELLREQGLLSVKQGCCVGECGACTVLVDGTAIDSCLYLAAWAEGKEIRTLE
GEAKGGKLSHVQQAYAKSGTVQCGFCTPGLIMATTAMLAKPREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK
>Mature_159_residues
MNHSETITTECTINGMPFQLHAAPGTPLSELLREQGLLSVKQGCCVGECGACTVLVDGTAIDSCLYLAAWAEGKEIRTLE
GEAKGGKLSHVQQAYAKSGTVQCGFCTPGLIMATTAMLAKPREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK

Specific function: Iron-sulfur subunit of the xanthine dehydrogenase complex [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789232, Length=159, Percent_Identity=98.7421383647799, Blast_Score=321, Evalue=1e-89,
Organism=Escherichia coli, GI1786480, Length=156, Percent_Identity=37.1794871794872, Blast_Score=97, Evalue=5e-22,
Organism=Escherichia coli, GI1789246, Length=136, Percent_Identity=33.8235294117647, Blast_Score=65, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540638, Length=138, Percent_Identity=40.5797101449275, Blast_Score=93, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17539860, Length=141, Percent_Identity=34.7517730496454, Blast_Score=81, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32566215, Length=141, Percent_Identity=34.0425531914894, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24647199, Length=155, Percent_Identity=34.8387096774194, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24647197, Length=163, Percent_Identity=32.5153374233129, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24647195, Length=163, Percent_Identity=32.5153374233129, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=33.5483870967742, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17737937, Length=131, Percent_Identity=38.1679389312977, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24647193, Length=156, Percent_Identity=34.6153846153846, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: NA

Molecular weight: Translated: 16940; Mature: 16940

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
10.1 %Cys+Met (Translated Protein)
6.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
10.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHSETITTECTINGMPFQLHAAPGTPLSELLREQGLLSVKQGCCVGECGACTVLVDGTA
CCCCCEEEEEEEECCCCEEEEECCCCCHHHHHHHCCCHHHHCCCCCCCCCEEEEEECCCH
IDSCLYLAAWAEGKEIRTLEGEAKGGKLSHVQQAYAKSGTVQCGFCTPGLIMATTAMLAK
HHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHC
PREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK
CCCCCEEHHHHHHHHCCCEEHHCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNHSETITTECTINGMPFQLHAAPGTPLSELLREQGLLSVKQGCCVGECGACTVLVDGTA
CCCCCEEEEEEEECCCCEEEEECCCCCHHHHHHHCCCHHHHCCCCCCCCCEEEEEECCCH
IDSCLYLAAWAEGKEIRTLEGEAKGGKLSHVQQAYAKSGTVQCGFCTPGLIMATTAMLAK
HHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHC
PREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK
CCCCCEEHHHHHHHHCCCEEHHCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]