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The map label for this gene is nlpD

Identifier: 30064099

GI number: 30064099

Start: 2834455

End: 2835594

Strand: Reverse

Name: nlpD

Synonym: S2958

Alternate gene names: 30064099

Gene position: 2835594-2834455 (Counterclockwise)

Preceding gene: 30064100

Following gene: 30064097

Centisome position: 61.65

GC content: 52.37

Gene sequence:

>1140_bases
ATGAGCGCGGGAAGCCCAAAATTCACCGTTCGCCGCATTGCGGCTTTGTCACTGGTTTCGCTATGGCTGGCAGGCTGTTC
TGACACTTCAAATCCACCGGCACCGGTCAGCTCCGTTAATGGCAATGCGCCTGCAAATACTAATTCTGGTATGTTGATTA
CGCCGCCGCCGAAAATGGGGACGACGTCTACAGCGCAGCAACCGCAAATTCAGCCGGTACAGCAGCCACAAATTCAGGCT
ACTCAACAACCGCAAATCCAGCCAGTGCAGCCAGTAGCTCAGCAGCCGGTACAGATGGAAAACGGACGCATCGTCTATAA
CCGTCAGTATGGGAACATTCCGAAAGGCAGTTATAGCGGCAGTACCTATACCGTGAAAAAAGGCGACACACTTTTCTATA
TCGCCTGGATTACTGGCAACGATTTCCGTGACCTTGCTCAGCGCAACAATATTCAGGCACCATACGCGCTGAACGTTGGT
CAGACCTTGCAGGTGGGTAATGCTTCCGGTACGCCAATCACTGGCGGAAATGCCATTACCCAGGCCGACGCAGCAGAGCA
AGGAGTTGTGATCAAGCCTGCACAAAATTCCACCGTTGCTGTTGCGTCGCAACCGACAATTACGTATTCTGAGTCTTCGG
GTGAACAGAGTGCTAACAAAATGTTGCCGAACAACAAGCCAACTGCGACCACGGTCACAGCGCCTGTAACGGTACCAACA
GCAAGCACAACCGAGCCGACTGTCAGCAGTACATCAACCAGTACGCCTATCTCCACCTGGCGCTGGCCGACTGAGGGCAA
AGTGATCGAAACCTTTGGCGCTTCTGAGGGGGGCAACAAGGGGATTGATATCGCAGGCAGCAAAGGACAGGCAATTATCG
CGACCGCAGATGGCCGCGTTGTTTATGCTGGTAACGCGCTGCGCGGCTACGGTAATCTGATTATCATCAAACATAATGAT
GATTACCTGAGTGCCTACGCCCATAACGACACAATGCTGGTCCGGGAACAACAAGAAGTGAAGGCGGGGCAAAAAATAGC
AACCATGGGTAGCACCGGAACCAGTTCAACACGCTTGCATTTTGAAATTCGTTACAAGGGGAAATCCGTAAACCCGCTGC
GTTATTTGCCGCAGCGATAA

Upstream 100 bases:

>100_bases
CGTAGGTCAGCGTATCGTGAACATCTTTTCCAGTGTTCAGTAGGGTGCCTTGCACGGTAATTATGTCACTGGTTATTAAC
CAATTTTTCCTGGGGGATAA

Downstream 100 bases:

>100_bases
ATCGGCGGAACCAGGCTTTTGCTTGAATGTTCCGTCAAGGGATCACGGGTAGGAGCCACCTTATGAGTCAGAATACGCTG
AAAGTTCATGATTTAAATGA

Product: lipoprotein NlpD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MSAGSPKFTVRRIAALSLVSLWLAGCSDTSNPPAPVSSVNGNAPANTNSGMLITPPPKMGTTSTAQQPQIQPVQQPQIQA
TQQPQIQPVQPVAQQPVQMENGRIVYNRQYGNIPKGSYSGSTYTVKKGDTLFYIAWITGNDFRDLAQRNNIQAPYALNVG
QTLQVGNASGTPITGGNAITQADAAEQGVVIKPAQNSTVAVASQPTITYSESSGEQSANKMLPNNKPTATTVTAPVTVPT
ASTTEPTVSSTSTSTPISTWRWPTEGKVIETFGASEGGNKGIDIAGSKGQAIIATADGRVVYAGNALRGYGNLIIIKHND
DYLSAYAHNDTMLVREQQEVKAGQKIATMGSTGTSSTRLHFEIRYKGKSVNPLRYLPQR

Sequences:

>Translated_379_residues
MSAGSPKFTVRRIAALSLVSLWLAGCSDTSNPPAPVSSVNGNAPANTNSGMLITPPPKMGTTSTAQQPQIQPVQQPQIQA
TQQPQIQPVQPVAQQPVQMENGRIVYNRQYGNIPKGSYSGSTYTVKKGDTLFYIAWITGNDFRDLAQRNNIQAPYALNVG
QTLQVGNASGTPITGGNAITQADAAEQGVVIKPAQNSTVAVASQPTITYSESSGEQSANKMLPNNKPTATTVTAPVTVPT
ASTTEPTVSSTSTSTPISTWRWPTEGKVIETFGASEGGNKGIDIAGSKGQAIIATADGRVVYAGNALRGYGNLIIIKHND
DYLSAYAHNDTMLVREQQEVKAGQKIATMGSTGTSSTRLHFEIRYKGKSVNPLRYLPQR
>Mature_378_residues
SAGSPKFTVRRIAALSLVSLWLAGCSDTSNPPAPVSSVNGNAPANTNSGMLITPPPKMGTTSTAQQPQIQPVQQPQIQAT
QQPQIQPVQPVAQQPVQMENGRIVYNRQYGNIPKGSYSGSTYTVKKGDTLFYIAWITGNDFRDLAQRNNIQAPYALNVGQ
TLQVGNASGTPITGGNAITQADAAEQGVVIKPAQNSTVAVASQPTITYSESSGEQSANKMLPNNKPTATTVTAPVTVPTA
STTEPTVSSTSTSTPISTWRWPTEGKVIETFGASEGGNKGIDIAGSKGQAIIATADGRVVYAGNALRGYGNLIIIKHNDD
YLSAYAHNDTMLVREQQEVKAGQKIATMGSTGTSSTRLHFEIRYKGKSVNPLRYLPQR

Specific function: May be involved in stationary-phase survival

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 LysM repeat

Homologues:

Organism=Escherichia coli, GI1789099, Length=379, Percent_Identity=100, Blast_Score=766, Evalue=0.0,
Organism=Escherichia coli, GI87082174, Length=264, Percent_Identity=43.5606060606061, Blast_Score=207, Evalue=7e-55,
Organism=Escherichia coli, GI87082297, Length=138, Percent_Identity=35.5072463768116, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NLPD_ECOLI (P0ADA3)

Other databases:

- EMBL:   L07869
- EMBL:   U29579
- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   D17549
- PIR:   B55522
- RefSeq:   AP_003309.1
- RefSeq:   NP_417222.1
- ProteinModelPortal:   P0ADA3
- DIP:   DIP-48067N
- STRING:   P0ADA3
- SWISS-2DPAGE:   P0ADA3
- PRIDE:   P0ADA3
- EnsemblBacteria:   EBESCT00000001497
- EnsemblBacteria:   EBESCT00000001498
- EnsemblBacteria:   EBESCT00000015121
- GeneID:   947011
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW2712
- KEGG:   eco:b2742
- EchoBASE:   EB2034
- EcoGene:   EG12111
- eggNOG:   COG0739
- GeneTree:   EBGT00050000009952
- HOGENOM:   HBG754735
- OMA:   HEARTEY
- ProtClustDB:   PRK10871
- BioCyc:   EcoCyc:EG12111-MONOMER
- Genevestigator:   P0ADA3
- GO:   GO:0001896
- GO:   GO:0006508
- InterPro:   IPR011055
- InterPro:   IPR016047
- InterPro:   IPR002886
- InterPro:   IPR018392
- InterPro:   IPR002482
- PANTHER:   PTHR21666:SF7
- SMART:   SM00257

Pfam domain/function: PF01476 LysM; PF01551 Peptidase_M23; SSF51261 Dup_hybrid_motif

EC number: NA

Molecular weight: Translated: 40149; Mature: 40018

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGSPKFTVRRIAALSLVSLWLAGCSDTSNPPAPVSSVNGNAPANTNSGMLITPPPKMG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
TTSTAQQPQIQPVQQPQIQATQQPQIQPVQPVAQQPVQMENGRIVYNRQYGNIPKGSYSG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCEEECCCEEEEEECCCCCCCCCCCC
STYTVKKGDTLFYIAWITGNDFRDLAQRNNIQAPYALNVGQTLQVGNASGTPITGGNAIT
CEEEEECCCEEEEEEEEECCCHHHHHHHCCCCCCEEECCCCEEEECCCCCCEECCCCCEE
QADAAEQGVVIKPAQNSTVAVASQPTITYSESSGEQSANKMLPNNKPTATTVTAPVTVPT
ECCCCCCCEEEECCCCCEEEEECCCEEEECCCCCCHHHHHCCCCCCCCEEEEEEEEEECC
ASTTEPTVSSTSTSTPISTWRWPTEGKVIETFGASEGGNKGIDIAGSKGQAIIATADGRV
CCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCEEEECCCCCEEEEECCCEE
VYAGNALRGYGNLIIIKHNDDYLSAYAHNDTMLVREQQEVKAGQKIATMGSTGTSSTRLH
EEECCCCCCCCCEEEEEECCCEEEEEECCCEEEEECHHHHHCCCEEEEECCCCCCCEEEE
FEIRYKGKSVNPLRYLPQR
EEEEECCCCCCHHHCCCCC
>Mature Secondary Structure 
SAGSPKFTVRRIAALSLVSLWLAGCSDTSNPPAPVSSVNGNAPANTNSGMLITPPPKMG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
TTSTAQQPQIQPVQQPQIQATQQPQIQPVQPVAQQPVQMENGRIVYNRQYGNIPKGSYSG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCEEECCCEEEEEECCCCCCCCCCCC
STYTVKKGDTLFYIAWITGNDFRDLAQRNNIQAPYALNVGQTLQVGNASGTPITGGNAIT
CEEEEECCCEEEEEEEEECCCHHHHHHHCCCCCCEEECCCCEEEECCCCCCEECCCCCEE
QADAAEQGVVIKPAQNSTVAVASQPTITYSESSGEQSANKMLPNNKPTATTVTAPVTVPT
ECCCCCCCEEEECCCCCEEEEECCCEEEECCCCCCHHHHHCCCCCCCCEEEEEEEEEECC
ASTTEPTVSSTSTSTPISTWRWPTEGKVIETFGASEGGNKGIDIAGSKGQAIIATADGRV
CCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCEEEECCCCCEEEEECCCEE
VYAGNALRGYGNLIIIKHNDDYLSAYAHNDTMLVREQQEVKAGQKIATMGSTGTSSTRLH
EEECCCCCCCCCEEEEEECCCEEEEEECCCEEEEECHHHHHCCCEEEEECCCCCCCEEEE
FEIRYKGKSVNPLRYLPQR
EEEEECCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8132457; 9278503; 8208244