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The map label for this gene is ompC

Identifier: 30063654

GI number: 30063654

Start: 2312489

End: 2313610

Strand: Reverse

Name: ompC

Synonym: S2429

Alternate gene names: 30063654

Gene position: 2313610-2312489 (Counterclockwise)

Preceding gene: 30063657

Following gene: 30063653

Centisome position: 50.3

GC content: 50.36

Gene sequence:

>1122_bases
ATGAAAGTTAAAGTACTGTCCCTCCTGGTCCCAGCTCTGCTGGTAGCAGGCGCAGCAAACGCTGCTGAAGTTTACAACAA
AGACGGCAACAAATTAGATCTGTACGGTAAAGTAGACGGCCTGCACTATTTCTCTGACGACAAGTCTGTAGATGGCGACC
AGACCTACATGCGTCTTGGCTTCAAAGGTGAAACTCAGGTTACTGACCAGCTGACCGGTTACGGCCAGTGGGAATATCAG
ATCCAGGGCAACAGCGCTGAAAACGAAAACAACTCCTGGACCCGTGTGGCATTCGCAGGTCTGAAATTCCAGGATGTAGG
TTCTTTCGACTACGGTCGTAACTACGGCGTAGTTTACGACGTAACTTCCTGGACCGACGTACTGCCAGAATTCGGTGGTG
ACACTTACGGTTCTGACAACTTCATGCAGCAGCGTGGTAACGGCTTCGCAACCTACCGTAGCACCGACTTCTTTGGTCTG
GTTGACGGTCTGAACTTCGCTGTTCAGTATCAGGGCAAAAACGGTAGCCCGGAAGGTGAAGGCATGACCAACAACGGTCG
TGAAGCTCTGCGTCAGAACGGTGACGGCGTTGGCGGTTCTATTACTTATGATTACGAAGGCTTCGGTATCGGTGCTGCAG
TTTCCAGCTCCAAACGTACTGATGACCAGAACTTCGGTCTGAACCGTTATGATGAGCGTTACATCGGTAATGGCGACCGC
GCTGAAACCTACACCGGTGGTCTGAAATACGACGCGAACAACATCTACCTAGCTGCTCAGTACACCCAGACCTACAACGC
AACTCGCGTAGGCAACTTGGGTTGGGCGAACAAAGCACAGAACTTCGAAGCTGTTGCTCAGTACCAGTTCGACTTCGGTC
TGCGTCCGTCCCTGGCTTACCTGCAGTCTAAAGGTAAAAACCTGGGTGTCATCAATGGTCGTAACTACGACGACGAAGAT
ATCCTGAAATATGTTGATGTTGGTGCGACCTACTACTTCAACAAAAACATGTCCACCTACGTTGACTACAAAATCAACCT
GCTGGACGACAACCAGTTCACTCGTGACGCTGGCATCAACACTGATAACATCGTAGCTCTGGGTCTGGTTTACCAGTTCT
AA

Upstream 100 bases:

>100_bases
ATTTTTGGGGAGAATGGACTTGCCGACTGATTAATGAGGGTTAATCAGTATGCAGTGGCATAAAAAAGCAAATAAAGGCA
TATAACAGAGGGTTAATAAC

Downstream 100 bases:

>100_bases
TCTCGATGGATATCGAACAAAGGGCCTGCGGGCCCTTTTTTCATTGTTTTCAGCGTACAAACACAGTTTTTTGGTGTACT
CTTGCGACCGTTCGCATGAG

Product: outer membrane porin protein C

Products: NA

Alternate protein names: Outer membrane protein 1B; Porin ompC [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDDKSVDGDQTYMRLGFKGETQVTDQLTGYGQWEYQ
IQGNSAENENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRSTDFFGL
VDGLNFAVQYQGKNGSPEGEGMTNNGREALRQNGDGVGGSITYDYEGFGIGAAVSSSKRTDDQNFGLNRYDERYIGNGDR
AETYTGGLKYDANNIYLAAQYTQTYNATRVGNLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGVINGRNYDDED
ILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLVYQF

Sequences:

>Translated_373_residues
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDDKSVDGDQTYMRLGFKGETQVTDQLTGYGQWEYQ
IQGNSAENENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRSTDFFGL
VDGLNFAVQYQGKNGSPEGEGMTNNGREALRQNGDGVGGSITYDYEGFGIGAAVSSSKRTDDQNFGLNRYDERYIGNGDR
AETYTGGLKYDANNIYLAAQYTQTYNATRVGNLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGVINGRNYDDED
ILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLVYQF
>Mature_373_residues
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDDKSVDGDQTYMRLGFKGETQVTDQLTGYGQWEYQ
IQGNSAENENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRSTDFFGL
VDGLNFAVQYQGKNGSPEGEGMTNNGREALRQNGDGVGGSITYDYEGFGIGAAVSSSKRTDDQNFGLNRYDERYIGNGDR
AETYTGGLKYDANNIYLAAQYTQTYNATRVGNLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGVINGRNYDDED
ILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLVYQF

Specific function: Forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane [H]

COG id: COG3203

COG function: function code M; Outer membrane protein (porin)

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Gram-negative porin family [H]

Homologues:

Organism=Escherichia coli, GI1788544, Length=377, Percent_Identity=92.3076923076923, Blast_Score=679, Evalue=0.0,
Organism=Escherichia coli, GI1787641, Length=384, Percent_Identity=65.8854166666667, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1786436, Length=378, Percent_Identity=56.3492063492063, Blast_Score=401, Evalue=1e-113,
Organism=Escherichia coli, GI1787160, Length=387, Percent_Identity=57.8811369509044, Blast_Score=395, Evalue=1e-111,

Paralogues:

None

Copy number: 6020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 19068 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001897
- InterPro:   IPR013793
- InterPro:   IPR001702 [H]

Pfam domain/function: PF00267 Porin_1 [H]

EC number: NA

Molecular weight: Translated: 41403; Mature: 41403

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS00576 GRAM_NEG_PORIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDDKSVDGDQTYMRLG
CCEEHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCEEEECCCCCCCCCCEEEEEC
FKGETQVTDQLTGYGQWEYQIQGNSAENENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYD
CCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCCEEEE
VTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRSTDFFGLVDGLNFAVQYQGKNGSPEGE
CCCHHHHHHHHCCCCCCCCHHHHHCCCEEEEEECCCCEEEECCCEEEEEECCCCCCCCCC
GMTNNGREALRQNGDGVGGSITYDYEGFGIGAAVSSSKRTDDQNFGLNRYDERYIGNGDR
CCCCCCHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCHHHCCCCCC
AETYTGGLKYDANNIYLAAQYTQTYNATRVGNLGWANKAQNFEAVAQYQFDFGLRPSLAY
CCEEECCEEECCCCEEEEEEEEECCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCHHHH
LQSKGKNLGVINGRNYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRDAGIN
HHHCCCEEEEECCCCCCHHHHHHHHHCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCCC
TDNIVALGLVYQF
CCCEEEEEEEECC
>Mature Secondary Structure
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDDKSVDGDQTYMRLG
CCEEHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCEEEECCCCCCCCCCEEEEEC
FKGETQVTDQLTGYGQWEYQIQGNSAENENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYD
CCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCCEEEE
VTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRSTDFFGLVDGLNFAVQYQGKNGSPEGE
CCCHHHHHHHHCCCCCCCCHHHHHCCCEEEEEECCCCEEEECCCEEEEEECCCCCCCCCC
GMTNNGREALRQNGDGVGGSITYDYEGFGIGAAVSSSKRTDDQNFGLNRYDERYIGNGDR
CCCCCCHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCHHHCCCCCC
AETYTGGLKYDANNIYLAAQYTQTYNATRVGNLGWANKAQNFEAVAQYQFDFGLRPSLAY
CCEEECCEEECCCCEEEEEEEEECCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCHHHH
LQSKGKNLGVINGRNYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRDAGIN
HHHCCCEEEEECCCCCCHHHHHHHHHCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCCC
TDNIVALGLVYQF
CCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]