| Definition | Shigella flexneri 2a str. 2457T, complete genome. |
|---|---|
| Accession | NC_004741 |
| Length | 4,599,354 |
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The map label for this gene is ddpD [H]
Identifier: 30063220
GI number: 30063220
Start: 1816087
End: 1817073
Strand: Direct
Name: ddpD [H]
Synonym: S1874
Alternate gene names: 30063220
Gene position: 1816087-1817073 (Clockwise)
Preceding gene: 30063219
Following gene: 30063224
Centisome position: 39.49
GC content: 54.1
Gene sequence:
>987_bases ATGACCCAACCCGTTCTGGACATTCAACAGCTGCATTTGAGTTTCCCCGGTTTTAACGGTGATGTTCACGCGCTCAACAA TGTGTCCTTGCAGATTAACCGCGGCGAAATTGTCGGTCTGGTGGGAGAATCCGGCTCAGGTAAATCAGTCACCGCAATGC TGATTATGCGTCTGCTACCGACGGGCAGTTATTGCGTACATCGGGGGCAGATTTCACTGCTGGGAGAAGATGTTCTTAAC GCTCGGGAAAAACAGCTTCGTCAGTGGCGCGGCGCACGAGTGGCGATGATCTTTCAGGAACCGATGACCGCCCTTAATCC GACACGTCGAATAGGTCTTCAGATGATGGACGTAATCCGCCATCATCAACCAATAAGTCGTCGGGAAGCCAGAGCTAAAG CGATTGCACTGCTGGAAGAGATGCAAATCCCGGATGCCGTGGAAGTTATGTCGCGCTATCCGTTTGAGCTTTCAGGTGGT ATGCGCCAGCGGGTAATGATTGCGCCGGCATTCTCCTGCGAGCCGCAATTGATTATTGCCGGCGAACCGACGACGGCGCT GGACGTCACAGTACAGTTGCAGGTACTGCGTTTGCTTAAACATAAAGCACGCGCCAGTGGAACTGCGGTACTGTTCATCA GCCATGATATGGCCGTGGTGTCGCAACTGTGCGATAGCGTTTACGTGATGTATGCCGGAAGCGTAATTGAAAGCGGCGGG ACGGCAGACGTTATCCATCATCCCCGGCATCCGTATACCATTGGTTTGCTGCAATGCGCACCAGAACATGGAGTACCACG CCAGCCATTACCCGCCATTCCAGGGACGGTACCAAACCTCACCCATTTGCCTGACGGCTGCGCTTTTCGCGATCGTTGCT ATGCGGCAGGTGCACAGTGTGAAAACGTCCCGGCGCTGACAGCGTGTGGTGACAACAACCAGCACTGCACCTGTTGGTAT CCGCAGCAGGAGGTCATAAGTGTCTGA
Upstream 100 bases:
>100_bases CATTTCCGGGGGCAGCGATTTTGCTTACCTCCGTCGGGTTTAATCTCTTTGGTGATGGTATTCGCGATCTGCTTGACCCG AAAGCAGGAGGAAAGCAGTC
Downstream 100 bases:
>100_bases CACGTTATTAACGTTACGCGACGTCCATATCAATTTTCCGGCCCGTAAAAACTGGCTTGGCAAATCTACGGAACATGTTC ATGCCATTAATGGTATTGAT
Product: putative ATP-binding component of a transport system
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 328; Mature: 327
Protein sequence:
>328_residues MTQPVLDIQQLHLSFPGFNGDVHALNNVSLQINRGEIVGLVGESGSGKSVTAMLIMRLLPTGSYCVHRGQISLLGEDVLN AREKQLRQWRGARVAMIFQEPMTALNPTRRIGLQMMDVIRHHQPISRREARAKAIALLEEMQIPDAVEVMSRYPFELSGG MRQRVMIAPAFSCEPQLIIAGEPTTALDVTVQLQVLRLLKHKARASGTAVLFISHDMAVVSQLCDSVYVMYAGSVIESGG TADVIHHPRHPYTIGLLQCAPEHGVPRQPLPAIPGTVPNLTHLPDGCAFRDRCYAAGAQCENVPALTACGDNNQHCTCWY PQQEVISV
Sequences:
>Translated_328_residues MTQPVLDIQQLHLSFPGFNGDVHALNNVSLQINRGEIVGLVGESGSGKSVTAMLIMRLLPTGSYCVHRGQISLLGEDVLN AREKQLRQWRGARVAMIFQEPMTALNPTRRIGLQMMDVIRHHQPISRREARAKAIALLEEMQIPDAVEVMSRYPFELSGG MRQRVMIAPAFSCEPQLIIAGEPTTALDVTVQLQVLRLLKHKARASGTAVLFISHDMAVVSQLCDSVYVMYAGSVIESGG TADVIHHPRHPYTIGLLQCAPEHGVPRQPLPAIPGTVPNLTHLPDGCAFRDRCYAAGAQCENVPALTACGDNNQHCTCWY PQQEVISV >Mature_327_residues TQPVLDIQQLHLSFPGFNGDVHALNNVSLQINRGEIVGLVGESGSGKSVTAMLIMRLLPTGSYCVHRGQISLLGEDVLNA REKQLRQWRGARVAMIFQEPMTALNPTRRIGLQMMDVIRHHQPISRREARAKAIALLEEMQIPDAVEVMSRYPFELSGGM RQRVMIAPAFSCEPQLIIAGEPTTALDVTVQLQVLRLLKHKARASGTAVLFISHDMAVVSQLCDSVYVMYAGSVIESGGT ADVIHHPRHPYTIGLLQCAPEHGVPRQPLPAIPGTVPNLTHLPDGCAFRDRCYAAGAQCENVPALTACGDNNQHCTCWYP QQEVISV
Specific function: Part of the ABC transporter complex DdpABCDF, which is probably involved in D,D-dipeptide transport. Probably responsible for energy coupling to the transport system [H]
COG id: COG0444
COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI42741659, Length=240, Percent_Identity=28.75, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI9665248, Length=239, Percent_Identity=28.4518828451883, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI21536378, Length=259, Percent_Identity=26.6409266409266, Blast_Score=72, Evalue=8e-13, Organism=Homo sapiens, GI255708477, Length=244, Percent_Identity=25.4098360655738, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI215820660, Length=244, Percent_Identity=28.6885245901639, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI20143975, Length=244, Percent_Identity=28.6885245901639, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1787759, Length=328, Percent_Identity=97.8658536585366, Blast_Score=657, Evalue=0.0, Organism=Escherichia coli, GI48994883, Length=322, Percent_Identity=42.8571428571429, Blast_Score=275, Evalue=4e-75, Organism=Escherichia coli, GI1789963, Length=318, Percent_Identity=41.5094339622642, Blast_Score=253, Evalue=8e-69, Organism=Escherichia coli, GI145693107, Length=265, Percent_Identity=46.7924528301887, Blast_Score=238, Evalue=5e-64, Organism=Escherichia coli, GI1788506, Length=283, Percent_Identity=43.1095406360424, Blast_Score=208, Evalue=5e-55, Organism=Escherichia coli, GI1787548, Length=328, Percent_Identity=36.890243902439, Blast_Score=204, Evalue=7e-54, Organism=Escherichia coli, GI1787500, Length=331, Percent_Identity=35.0453172205438, Blast_Score=188, Evalue=4e-49, Organism=Escherichia coli, GI1789962, Length=333, Percent_Identity=33.3333333333333, Blast_Score=179, Evalue=2e-46, Organism=Escherichia coli, GI1787758, Length=330, Percent_Identity=33.9393939393939, Blast_Score=176, Evalue=1e-45, Organism=Escherichia coli, GI1789890, Length=251, Percent_Identity=33.8645418326693, Blast_Score=137, Evalue=1e-33, Organism=Escherichia coli, GI1789891, Length=230, Percent_Identity=36.0869565217391, Blast_Score=135, Evalue=3e-33, Organism=Escherichia coli, GI48994997, Length=260, Percent_Identity=34.6153846153846, Blast_Score=121, Evalue=6e-29, Organism=Escherichia coli, GI1786398, Length=248, Percent_Identity=33.0645161290323, Blast_Score=114, Evalue=7e-27, Organism=Escherichia coli, GI1787547, Length=271, Percent_Identity=28.7822878228782, Blast_Score=111, Evalue=6e-26, Organism=Escherichia coli, GI1789032, Length=236, Percent_Identity=32.2033898305085, Blast_Score=108, Evalue=6e-25, Organism=Escherichia coli, GI1786703, Length=235, Percent_Identity=31.9148936170213, Blast_Score=98, Evalue=8e-22, Organism=Escherichia coli, GI1788761, Length=259, Percent_Identity=29.3436293436293, Blast_Score=98, Evalue=9e-22, Organism=Escherichia coli, GI1787105, Length=219, Percent_Identity=33.7899543378995, Blast_Score=96, Evalue=4e-21, Organism=Escherichia coli, GI1787712, Length=241, Percent_Identity=30.2904564315353, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1788225, Length=243, Percent_Identity=29.6296296296296, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI1786319, Length=274, Percent_Identity=26.6423357664234, Blast_Score=91, Evalue=8e-20, Organism=Escherichia coli, GI1788644, Length=261, Percent_Identity=31.0344827586207, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1789672, Length=244, Percent_Identity=29.5081967213115, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI1787089, Length=228, Percent_Identity=29.3859649122807, Blast_Score=86, Evalue=4e-18, Organism=Escherichia coli, GI1790162, Length=250, Percent_Identity=25.2, Blast_Score=85, Evalue=7e-18, Organism=Escherichia coli, GI87081791, Length=255, Percent_Identity=30.1960784313725, Blast_Score=85, Evalue=8e-18, Organism=Escherichia coli, GI87081709, Length=233, Percent_Identity=28.3261802575107, Blast_Score=83, Evalue=3e-17, Organism=Escherichia coli, GI1788450, Length=235, Percent_Identity=26.8085106382979, Blast_Score=83, Evalue=3e-17, Organism=Escherichia coli, GI1789593, Length=234, Percent_Identity=29.4871794871795, Blast_Score=82, Evalue=7e-17, Organism=Escherichia coli, GI1787029, Length=241, Percent_Identity=29.045643153527, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI1790525, Length=249, Percent_Identity=30.1204819277108, Blast_Score=81, Evalue=1e-16, Organism=Escherichia coli, GI48995001, Length=235, Percent_Identity=29.7872340425532, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1787370, Length=234, Percent_Identity=27.3504273504274, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1790467, Length=242, Percent_Identity=25.6198347107438, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI87081834, Length=202, Percent_Identity=31.6831683168317, Blast_Score=78, Evalue=9e-16, Organism=Escherichia coli, GI1786872, Length=210, Percent_Identity=29.5238095238095, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787792, Length=249, Percent_Identity=28.9156626506024, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI1789991, Length=272, Percent_Identity=27.2058823529412, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI1787143, Length=245, Percent_Identity=30.2040816326531, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI48994943, Length=228, Percent_Identity=27.1929824561404, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1790190, Length=238, Percent_Identity=27.7310924369748, Blast_Score=75, Evalue=7e-15, Organism=Escherichia coli, GI1786803, Length=248, Percent_Identity=24.5967741935484, Blast_Score=74, Evalue=2e-14, Organism=Escherichia coli, GI1790739, Length=229, Percent_Identity=28.3842794759825, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1789873, Length=203, Percent_Identity=29.5566502463054, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1790534, Length=216, Percent_Identity=30.0925925925926, Blast_Score=72, Evalue=6e-14, Organism=Escherichia coli, GI1786698, Length=221, Percent_Identity=28.0542986425339, Blast_Score=72, Evalue=7e-14, Organism=Escherichia coli, GI1786563, Length=233, Percent_Identity=27.8969957081545, Blast_Score=71, Evalue=8e-14, Organism=Escherichia coli, GI87082267, Length=235, Percent_Identity=27.6595744680851, Blast_Score=71, Evalue=8e-14, Organism=Escherichia coli, GI1789864, Length=257, Percent_Identity=26.8482490272374, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1786345, Length=232, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1789586, Length=215, Percent_Identity=26.9767441860465, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI1788472, Length=237, Percent_Identity=26.5822784810127, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1787112, Length=247, Percent_Identity=26.7206477732794, Blast_Score=65, Evalue=9e-12, Organism=Escherichia coli, GI1786253, Length=219, Percent_Identity=27.8538812785388, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1786654, Length=262, Percent_Identity=24.4274809160305, Blast_Score=61, Evalue=9e-11, Organism=Caenorhabditis elegans, GI212646699, Length=249, Percent_Identity=28.1124497991968, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI115534520, Length=276, Percent_Identity=29.3478260869565, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI193202349, Length=235, Percent_Identity=26.3829787234043, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI25146777, Length=252, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17541710, Length=237, Percent_Identity=28.2700421940928, Blast_Score=79, Evalue=4e-15, Organism=Caenorhabditis elegans, GI71992285, Length=249, Percent_Identity=29.3172690763052, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI193209708, Length=246, Percent_Identity=25.609756097561, Blast_Score=76, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17567265, Length=240, Percent_Identity=27.9166666666667, Blast_Score=75, Evalue=6e-14, Organism=Caenorhabditis elegans, GI193208177, Length=249, Percent_Identity=27.710843373494, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17558664, Length=238, Percent_Identity=29.8319327731092, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI71996809, Length=245, Percent_Identity=26.1224489795918, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17567269, Length=252, Percent_Identity=25.7936507936508, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI115533592, Length=245, Percent_Identity=27.3469387755102, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17569143, Length=251, Percent_Identity=28.2868525896414, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI193211015, Length=245, Percent_Identity=26.9387755102041, Blast_Score=71, Evalue=8e-13, Organism=Caenorhabditis elegans, GI193211017, Length=245, Percent_Identity=26.9387755102041, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI71984940, Length=245, Percent_Identity=26.1224489795918, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI115535101, Length=245, Percent_Identity=26.1224489795918, Blast_Score=68, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17569145, Length=235, Percent_Identity=27.6595744680851, Blast_Score=67, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322640, Length=258, Percent_Identity=27.906976744186, Blast_Score=82, Evalue=9e-17, Organism=Saccharomyces cerevisiae, GI6323217, Length=248, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=5e-15, Organism=Drosophila melanogaster, GI85726357, Length=269, Percent_Identity=26.0223048327138, Blast_Score=78, Evalue=8e-15, Organism=Drosophila melanogaster, GI24641565, Length=221, Percent_Identity=31.2217194570136, Blast_Score=72, Evalue=6e-13, Organism=Drosophila melanogaster, GI161076684, Length=241, Percent_Identity=27.3858921161826, Blast_Score=71, Evalue=1e-12, Organism=Drosophila melanogaster, GI24581617, Length=241, Percent_Identity=27.3858921161826, Blast_Score=71, Evalue=1e-12, Organism=Drosophila melanogaster, GI24581615, Length=241, Percent_Identity=27.3858921161826, Blast_Score=71, Evalue=1e-12, Organism=Drosophila melanogaster, GI161076682, Length=241, Percent_Identity=27.3858921161826, Blast_Score=71, Evalue=1e-12, Organism=Drosophila melanogaster, GI28574533, Length=251, Percent_Identity=26.6932270916335, Blast_Score=71, Evalue=1e-12, Organism=Drosophila melanogaster, GI23397593, Length=248, Percent_Identity=27.4193548387097, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI116007184, Length=249, Percent_Identity=26.9076305220884, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI85724864, Length=241, Percent_Identity=25.3112033195021, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24580555, Length=241, Percent_Identity=25.3112033195021, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI85816269, Length=241, Percent_Identity=25.3112033195021, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24580553, Length=241, Percent_Identity=25.3112033195021, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI221500365, Length=249, Percent_Identity=26.9076305220884, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI17136592, Length=226, Percent_Identity=26.1061946902655, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 - InterPro: IPR010066 - InterPro: IPR013563 [H]
Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]
EC number: NA
Molecular weight: Translated: 35935; Mature: 35804
Theoretical pI: Translated: 7.33; Mature: 7.33
Prosite motif: PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
3.0 %Cys (Translated Protein) 4.0 %Met (Translated Protein) 7.0 %Cys+Met (Translated Protein) 3.1 %Cys (Mature Protein) 3.7 %Met (Mature Protein) 6.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTQPVLDIQQLHLSFPGFNGDVHALNNVSLQINRGEIVGLVGESGSGKSVTAMLIMRLLP CCCCHHHHHHHHEECCCCCCCEEEECCEEEEEECCEEEEEECCCCCCCHHHHHHHHHHCC TGSYCVHRGQISLLGEDVLNAREKQLRQWRGARVAMIFQEPMTALNPTRRIGLQMMDVIR CCCCEEECCCEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHCCHHHHHHHHHHHHHH HHQPISRREARAKAIALLEEMQIPDAVEVMSRYPFELSGGMRQRVMIAPAFSCEPQLIIA HCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEECCCCCEEEEEEECCCCCCCEEEE GEPTTALDVTVQLQVLRLLKHKARASGTAVLFISHDMAVVSQLCDSVYVMYAGSVIESGG CCCCCEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHCHHHCCCC TADVIHHPRHPYTIGLLQCAPEHGVPRQPLPAIPGTVPNLTHLPDGCAFRDRCYAAGAQC CEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCC ENVPALTACGDNNQHCTCWYPQQEVISV CCCCEEEEECCCCCEEEEECCHHHHHCC >Mature Secondary Structure TQPVLDIQQLHLSFPGFNGDVHALNNVSLQINRGEIVGLVGESGSGKSVTAMLIMRLLP CCCHHHHHHHHEECCCCCCCEEEECCEEEEEECCEEEEEECCCCCCCHHHHHHHHHHCC TGSYCVHRGQISLLGEDVLNAREKQLRQWRGARVAMIFQEPMTALNPTRRIGLQMMDVIR CCCCEEECCCEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHCCHHHHHHHHHHHHHH HHQPISRREARAKAIALLEEMQIPDAVEVMSRYPFELSGGMRQRVMIAPAFSCEPQLIIA HCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEECCCCCEEEEEEECCCCCCCEEEE GEPTTALDVTVQLQVLRLLKHKARASGTAVLFISHDMAVVSQLCDSVYVMYAGSVIESGG CCCCCEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHCHHHCCCC TADVIHHPRHPYTIGLLQCAPEHGVPRQPLPAIPGTVPNLTHLPDGCAFRDRCYAAGAQC CEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCC ENVPALTACGDNNQHCTCWYPQQEVISV CCCCEEEEECCCCCEEEEECCHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 9097039; 9278503; 9751644 [H]