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The map label for this gene is dmsD

Identifier: 30063106

GI number: 30063106

Start: 1678764

End: 1679378

Strand: Direct

Name: dmsD

Synonym: S1744

Alternate gene names: 30063106

Gene position: 1678764-1679378 (Clockwise)

Preceding gene: 30063105

Following gene: 161486485

Centisome position: 36.5

GC content: 53.33

Gene sequence:

>615_bases
ATGACCCATTTTTCACAGCAAGATAATTTTTCTGTCGCGGCGCGCGTGTTGGGCGCGCTGTTTTATTACGCTCCAGAGAG
TGCGGAAGCCGCACCTCTGGTTGCGGTACTCACCAGTGACGGCTGGGAAACTCAGTGGCCTCTACCAGAAGCGTCATTAG
CGCCGCTGGTGACGGCTTTTCAGACACAGTGTGAAGAGACTCACGCCCAGGCCTGGCAGCGTTTGTTTGTCGGCCCGTGG
GCACTGCCGTCTCCGCCGTGGGGGTCGGTCTGGCTGGATCGCGAATCTGTGCTGTTTGGCGATTCAACATTGGCACTTCG
TCAGTGGATGCGCGAGAAAGGCATTCAGTTTGAAATGAAGCAAAACGAACCGGAAGATCATTTTGGTTCACTGCTGTTGA
TGGCTGCGTGGTTGGCGGAGAATGGTCGCCAGACAGAATGCGAAGAATTGCTGGCATGGCACCTTTTTCCGTGGTCAACA
CGTTTTCTTGATGTTTTTATCGAAAAAGCAGAACACCCTTTCTACCGTGCACTGGGTGAACTGGCTCGCTTAACGCTGGC
GCAATGGCAATCACAACTGTTGATTCCTGTCGCGGTTAAACCACTCTTTCGATAG

Upstream 100 bases:

>100_bases
CGGGCGTGTGCTCTTTTATGGCCTGCACATGACAGTAGGAATGGCTATTGCAGGTTAACAAATTGGTGCGGGGCAACCCG
CACATTTCAGGATGTTAGGA

Downstream 100 bases:

>100_bases
GATCACCGTAATATTGCCGGATGGTGACGATTACGCGCGATTCGGCAATAATACGTTACAATGTCACGTTTTTTTATCTC
TTAAAGCACGCACTGCTTTT

Product: twin-argninine leader-binding protein DmsD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MTHFSQQDNFSVAARVLGALFYYAPESAEAAPLVAVLTSDGWETQWPLPEASLAPLVTAFQTQCEETHAQAWQRLFVGPW
ALPSPPWGSVWLDRESVLFGDSTLALRQWMREKGIQFEMKQNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWST
RFLDVFIEKAEHPFYRALGELARLTLAQWQSQLLIPVAVKPLFR

Sequences:

>Translated_204_residues
MTHFSQQDNFSVAARVLGALFYYAPESAEAAPLVAVLTSDGWETQWPLPEASLAPLVTAFQTQCEETHAQAWQRLFVGPW
ALPSPPWGSVWLDRESVLFGDSTLALRQWMREKGIQFEMKQNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWST
RFLDVFIEKAEHPFYRALGELARLTLAQWQSQLLIPVAVKPLFR
>Mature_203_residues
THFSQQDNFSVAARVLGALFYYAPESAEAAPLVAVLTSDGWETQWPLPEASLAPLVTAFQTQCEETHAQAWQRLFVGPWA
LPSPPWGSVWLDRESVLFGDSTLALRQWMREKGIQFEMKQNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWSTR
FLDVFIEKAEHPFYRALGELARLTLAQWQSQLLIPVAVKPLFR

Specific function: Binds to the twin-arginine signal peptide of dmsA and torA. Could be required for the biogenesis of DMSO reductase rather than for the targeting of dmsA to the inner membrane

COG id: COG3381

COG function: function code R; Uncharacterized component of anaerobic dehydrogenases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Cytoplasm (By similarity). Note=Mainly cytoplasmic under aerobic conditions, and found in the inner membrane under anaerobic conditions (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the torD/dmsD family. DmsD subfamily

Homologues:

Organism=Escherichia coli, GI87081942, Length=204, Percent_Identity=100, Blast_Score=412, Evalue=1e-117,
Organism=Escherichia coli, GI1787272, Length=180, Percent_Identity=30.5555555555556, Blast_Score=84, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DMSD_ECO57 (P69854)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   A90916
- RefSeq:   NP_288026.2
- RefSeq:   NP_310324.2
- ProteinModelPortal:   P69854
- SMR:   P69854
- EnsemblBacteria:   EBESCT00000026018
- EnsemblBacteria:   EBESCT00000058352
- GeneID:   912340
- GeneID:   961535
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z2581
- KEGG:   ecs:ECs2297
- GeneTree:   EBGT00050000011387
- HOGENOM:   HBG741966
- OMA:   PEDHIGL
- ProtClustDB:   PRK11621
- BioCyc:   ECOL83334:ECS2297-MONOMER
- GO:   GO:0005737
- InterPro:   IPR020945

Pfam domain/function: PF02613 Nitrate_red_del

EC number: NA

Molecular weight: Translated: 23345; Mature: 23214

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHFSQQDNFSVAARVLGALFYYAPESAEAAPLVAVLTSDGWETQWPLPEASLAPLVTAF
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHH
QTQCEETHAQAWQRLFVGPWALPSPPWGSVWLDRESVLFGDSTLALRQWMREKGIQFEMK
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEECCHHHHHHHHHHHCCCEEEEC
QNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWSTRFLDVFIEKAEHPFYRALGE
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHH
LARLTLAQWQSQLLIPVAVKPLFR
HHHHHHHHHHHCEEHHHHHCCCCC
>Mature Secondary Structure 
THFSQQDNFSVAARVLGALFYYAPESAEAAPLVAVLTSDGWETQWPLPEASLAPLVTAF
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHH
QTQCEETHAQAWQRLFVGPWALPSPPWGSVWLDRESVLFGDSTLALRQWMREKGIQFEMK
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEECCHHHHHHHHHHHCCCEEEEC
QNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWSTRFLDVFIEKAEHPFYRALGE
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHH
LARLTLAQWQSQLLIPVAVKPLFR
HHHHHHHHHHHCEEHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796