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The map label for this gene is yeaE [H]

Identifier: 30062957

GI number: 30062957

Start: 1515578

End: 1516339

Strand: Direct

Name: yeaE [H]

Synonym: S1557

Alternate gene names: 30062957

Gene position: 1515578-1516339 (Clockwise)

Preceding gene: 30062956

Following gene: 30062960

Centisome position: 32.95

GC content: 50.39

Gene sequence:

>762_bases
ATGCAACAAAAAATGATTCAATTTAGTGGCGATGTCTCACTGCCAGCCATAGGGCAGGGAACATGGTATATGGGCGAAGA
TGCCAGTCAGCGCAAAACAGAAGTTGCTGCACTACGCGCAGGCATTGAACTCGGTTTAACCCTCATTGATACCGCCGAAA
TGTATGCCGATGGCGGTGCCGAAAAGGTGGTTGGGGAAGCATTAACCGGTCTGCGAGAGAAGGTCTTTCTCGTCTCTAAA
GTCTATCCGTGGAATGCTGGCGGGCAAAAAGCGATAAATGCATGCGAAGCCAGTTTACGCCGTCTCAATACTGACTATCT
CGATCTCTACTTATTACACTGGTCTGGCAGTTTCGCTTTTGAAGAGACTGTTGCTGCGATGGAAAAATTGATCGCCCAGG
GAAAAATCCGTCGCTGGGGCGTTTCTAACCTTGGTTATGCCGATATGCAGGAACTCTGGCAGCTGCCGGGGGGAAATCAG
TGTGCCACTAATCAGGTGCTTTACCATCTCGGTTCACGAGGGATTGAGTACGATCTACTCCCCTGGTGCCAGCAACAGCA
GATGCCGGTGATGGCTTACAGTCCATTAGCCCAGGCCGGGCGGTTGCGCAATGGACTGTTAAAAAACGCGGTAGTCAACG
AAATTGCACATGTCCAACAACATGCAGCTGCGCTTGAGGTCGAACTTTCGTCAGCGGAATTAGCTATGCTGGATAAGGCA
TATCCGGCACCAAAAGGAAAAACTGCGCTGGATATGGTGTGA

Upstream 100 bases:

>100_bases
ACAAATTCTGATAATGCATCTTTCCAGGGCATTTTGTGCATAAAAACAGGGCGTCACGCCCTGTTTTGCATTACGGTGGT
GCAATACCTGGGAGGAAACA

Downstream 100 bases:

>100_bases
TGTTGATACGTGCCGGATGCATCGCACCCGGCACACAACATTAACGCAAATTAACGTTTGGCAACGCGAATGGATTGCGC
CAGATGTGCAGGTTTCTCTT

Product: putative aldehyde reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLREKVFLVSK
VYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAFEETVAAMEKLIAQGKIRRWGVSNLGYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHVQQHAAALEVELSSAELAMLDKA
YPAPKGKTALDMV

Sequences:

>Translated_253_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLREKVFLVSK
VYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAFEETVAAMEKLIAQGKIRRWGVSNLGYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHVQQHAAALEVELSSAELAMLDKA
YPAPKGKTALDMV
>Mature_253_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLREKVFLVSK
VYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAFEETVAAMEKLIAQGKIRRWGVSNLGYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHVQQHAAALEVELSSAELAMLDKA
YPAPKGKTALDMV

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI223468663, Length=253, Percent_Identity=28.4584980237154, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI291291012, Length=246, Percent_Identity=26.8292682926829, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI223718702, Length=200, Percent_Identity=32, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI310109922, Length=193, Percent_Identity=31.0880829015544, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI24497577, Length=216, Percent_Identity=28.7037037037037, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI5174391, Length=216, Percent_Identity=28.7037037037037, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI41327764, Length=171, Percent_Identity=30.9941520467836, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1788081, Length=284, Percent_Identity=87.6760563380282, Blast_Score=498, Evalue=1e-142,
Organism=Escherichia coli, GI87081735, Length=200, Percent_Identity=32.5, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788070, Length=234, Percent_Identity=29.9145299145299, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1786400, Length=204, Percent_Identity=28.4313725490196, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082198, Length=209, Percent_Identity=30.622009569378, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789199, Length=241, Percent_Identity=30.7053941908714, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789375, Length=235, Percent_Identity=25.531914893617, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17552492, Length=221, Percent_Identity=32.579185520362, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17564128, Length=230, Percent_Identity=29.5652173913043, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71998625, Length=215, Percent_Identity=31.6279069767442, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561298, Length=237, Percent_Identity=30.379746835443, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17561300, Length=243, Percent_Identity=28.8065843621399, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17550248, Length=218, Percent_Identity=26.605504587156, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17566692, Length=216, Percent_Identity=27.3148148148148, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17537077, Length=239, Percent_Identity=28.0334728033473, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17537075, Length=239, Percent_Identity=28.0334728033473, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6324694, Length=245, Percent_Identity=30.2040816326531, Blast_Score=79, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6320079, Length=212, Percent_Identity=29.2452830188679, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6322556, Length=222, Percent_Identity=26.5765765765766, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24644950, Length=233, Percent_Identity=30.0429184549356, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45553081, Length=221, Percent_Identity=24.4343891402715, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 27736; Mature: 27736

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGA
CCCCCEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCH
EKVVGEALTGLREKVFLVSKVYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAF
HHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHH
EETVAAMEKLIAQGKIRRWGVSNLGYADMQELWQLPGGNQCATNQVLYHLGSRGIEYDLL
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCC
PWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHVQQHAAALEVELSSAELAMLDKA
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHC
YPAPKGKTALDMV
CCCCCCCCCCCCC
>Mature Secondary Structure
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGA
CCCCCEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCH
EKVVGEALTGLREKVFLVSKVYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAF
HHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHH
EETVAAMEKLIAQGKIRRWGVSNLGYADMQELWQLPGGNQCATNQVLYHLGSRGIEYDLL
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCC
PWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHVQQHAAALEVELSSAELAMLDKA
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHC
YPAPKGKTALDMV
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]