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The map label for this gene is citC

Identifier: 30062075

GI number: 30062075

Start: 552534

End: 553679

Strand: Reverse

Name: citC

Synonym: S0542

Alternate gene names: 30062075

Gene position: 553679-552534 (Counterclockwise)

Preceding gene: 30062076

Following gene: 30062074

Centisome position: 12.04

GC content: 49.39

Gene sequence:

>1146_bases
GTGAAAATAAAAGGTTATCAGTTTGCAACATTGAACAACATTCGTTGCAAATCGATAACAACATGCACCTTCAGGATACT
ATTTATTATGTTCGGCAATGATATTTTCACCCGCGTAAAACGTTCAGAAAATAAAAAAATGGCGGAAATCGCCCAATTCC
TGCATGAAAATGATTTGAGCGTTGACACCACAGTCGAAGTATTTATTACCGTAACCCGCGATGAAAAGCTTATCGCGTGC
GGTGGAATTGCCGGAAATATTATTAAATGCGTTGCTATCAGTGAATCCGTTCGCGGTGAAGGACTGGCGCTGACATTAGC
CACTGAACTGATAAACCTCGCCTATGAGCGGCACAGCACGCATCTGTTTATTTATACCAAAACCGAATACGAGGCGCTGT
TCCGCCAGTGCGGTTTTTCCACGCTGACCTGCGTACCCGGCGTGATGGTGCTGATGGAAAACAGCGCCACGCGACTGAAA
CGCTATGCCGAATCGCTGAAAAAATTTCGTCATCCAGGGAACAAGATTGGCTGCATTGTGATGAACGCCAATCCCTTTAC
GAATGGTCACCGTTATCTGATTCAACAAGCTGCGGCACAGTGCGACTGGTTGCATCTGTTTTTAGTCAAAGAAGATTCTT
CACGCTTCCCCTATGAAGACCGGCTGGATCTGGTGTTAAAAGGCACCGCCGATATTCCACGCCTGACTGTGCATCGCGGC
TCAGAATACATCATCTCCCGCGCTACGTTCCCTTGCTACTTCATTAAAGAACAGAGCGTCATTAACCATTGTTACACCGA
AATTGATCTGAAGATTTTCCGTCAGTACCTCGCTCCCGCGCTTGGTGTAACTCACCGCTTTGTCGGTACTGAACCCTTTT
GTCGCGTTACCGCCCAGTACAACCAGGATATGCGCTACTGGCTGGAAACGCCGACTATCTCCGCAGCGCCCATCGAACTG
GTTGAAATTGAGCGGCTGCGTTACCAGGAGATGCCGATATCCGCTTCCCGGGTACGTCAACTGCTGGCGAAAAACGATCT
CACGGCTATCGCGCCGCTGGTCCCTGCAGTCACGCTGCATTATTTGCAGAACCTGCTTGAGCACTCCCGCCAGGACGCGG
CAGCTCGTCAAAAGACCCCCGCATGA

Upstream 100 bases:

>100_bases
ACTCTATGTGAAATAAATCAAAATTTCACGCCGAAATACTCCTTAGGATGTATAGCGAAAGGAGAAAAAGATATACCTCG
ATCACCCCCCTTTCTCCCAA

Downstream 100 bases:

>100_bases
GAAACAGGTGAAAAATGAAAATAAACCAGCCCGCCGTTGCAGGCACCCTTGAGTCTGGGGATGTGATGATACGCATCGCC
CCACTCGATACGCAGGATAT

Product: citrate lyase synthetase (citrate (pro-3S)-lyase ligase

Products: NA

Alternate protein names: Acetate:SH-citrate lyase ligase; Citrate lyase synthetase [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKIKGYQFATLNNIRCKSITTCTFRILFIMFGNDIFTRVKRSENKKMAEIAQFLHENDLSVDTTVEVFITVTRDEKLIAC
GGIAGNIIKCVAISESVRGEGLALTLATELINLAYERHSTHLFIYTKTEYEALFRQCGFSTLTCVPGVMVLMENSATRLK
RYAESLKKFRHPGNKIGCIVMNANPFTNGHRYLIQQAAAQCDWLHLFLVKEDSSRFPYEDRLDLVLKGTADIPRLTVHRG
SEYIISRATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGVTHRFVGTEPFCRVTAQYNQDMRYWLETPTISAAPIEL
VEIERLRYQEMPISASRVRQLLAKNDLTAIAPLVPAVTLHYLQNLLEHSRQDAAARQKTPA

Sequences:

>Translated_381_residues
MKIKGYQFATLNNIRCKSITTCTFRILFIMFGNDIFTRVKRSENKKMAEIAQFLHENDLSVDTTVEVFITVTRDEKLIAC
GGIAGNIIKCVAISESVRGEGLALTLATELINLAYERHSTHLFIYTKTEYEALFRQCGFSTLTCVPGVMVLMENSATRLK
RYAESLKKFRHPGNKIGCIVMNANPFTNGHRYLIQQAAAQCDWLHLFLVKEDSSRFPYEDRLDLVLKGTADIPRLTVHRG
SEYIISRATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGVTHRFVGTEPFCRVTAQYNQDMRYWLETPTISAAPIEL
VEIERLRYQEMPISASRVRQLLAKNDLTAIAPLVPAVTLHYLQNLLEHSRQDAAARQKTPA
>Mature_381_residues
MKIKGYQFATLNNIRCKSITTCTFRILFIMFGNDIFTRVKRSENKKMAEIAQFLHENDLSVDTTVEVFITVTRDEKLIAC
GGIAGNIIKCVAISESVRGEGLALTLATELINLAYERHSTHLFIYTKTEYEALFRQCGFSTLTCVPGVMVLMENSATRLK
RYAESLKKFRHPGNKIGCIVMNANPFTNGHRYLIQQAAAQCDWLHLFLVKEDSSRFPYEDRLDLVLKGTADIPRLTVHRG
SEYIISRATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGVTHRFVGTEPFCRVTAQYNQDMRYWLETPTISAAPIEL
VEIERLRYQEMPISASRVRQLLAKNDLTAIAPLVPAVTLHYLQNLLEHSRQDAAARQKTPA

Specific function: Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase [H]

COG id: COG3053

COG function: function code C; Citrate lyase synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI87081765, Length=352, Percent_Identity=99.4318181818182, Blast_Score=731, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005216
- InterPro:   IPR013166
- InterPro:   IPR004821
- InterPro:   IPR014729 [H]

Pfam domain/function: PF08218 Citrate_ly_lig [H]

EC number: =6.2.1.22 [H]

Molecular weight: Translated: 43475; Mature: 43475

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKGYQFATLNNIRCKSITTCTFRILFIMFGNDIFTRVKRSENKKMAEIAQFLHENDLS
CCCCCEEEEEECCCEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCCC
VDTTVEVFITVTRDEKLIACGGIAGNIIKCVAISESVRGEGLALTLATELINLAYERHST
CCEEEEEEEEEECCCEEEEECCCCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHHCCCC
HLFIYTKTEYEALFRQCGFSTLTCVPGVMVLMENSATRLKRYAESLKKFRHPGNKIGCIV
EEEEEECCHHHHHHHHCCCCHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEE
MNANPFTNGHRYLIQQAAAQCDWLHLFLVKEDSSRFPYEDRLDLVLKGTADIPRLTVHRG
ECCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCCCEEEEECC
SEYIISRATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGVTHRFVGTEPFCRVTAQY
CCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
NQDMRYWLETPTISAAPIELVEIERLRYQEMPISASRVRQLLAKNDLTAIAPLVPAVTLH
CCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
YLQNLLEHSRQDAAARQKTPA
HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIKGYQFATLNNIRCKSITTCTFRILFIMFGNDIFTRVKRSENKKMAEIAQFLHENDLS
CCCCCEEEEEECCCEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCCC
VDTTVEVFITVTRDEKLIACGGIAGNIIKCVAISESVRGEGLALTLATELINLAYERHST
CCEEEEEEEEEECCCEEEEECCCCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHHCCCC
HLFIYTKTEYEALFRQCGFSTLTCVPGVMVLMENSATRLKRYAESLKKFRHPGNKIGCIV
EEEEEECCHHHHHHHHCCCCHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEE
MNANPFTNGHRYLIQQAAAQCDWLHLFLVKEDSSRFPYEDRLDLVLKGTADIPRLTVHRG
ECCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCCCEEEEECC
SEYIISRATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGVTHRFVGTEPFCRVTAQY
CCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
NQDMRYWLETPTISAAPIELVEIERLRYQEMPISASRVRQLLAKNDLTAIAPLVPAVTLH
CCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
YLQNLLEHSRQDAAARQKTPA
HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]