| Definition | Shigella flexneri 2a str. 2457T, complete genome. |
|---|---|
| Accession | NC_004741 |
| Length | 4,599,354 |
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The map label for this gene is gcd
Identifier: 30061689
GI number: 30061689
Start: 136417
End: 138807
Strand: Reverse
Name: gcd
Synonym: S0123
Alternate gene names: 30061689
Gene position: 138807-136417 (Counterclockwise)
Preceding gene: 30061691
Following gene: 30061687
Centisome position: 3.02
GC content: 55.71
Gene sequence:
>2391_bases ATGGCAATTAACAATACAGCCTCGCGACGATTACTCGTCACGCTAACAGCCCTTTTTGCAGCGCTTTGCGGGCTGTATCT ACTCATTGGCGGAGGCTGGCTGGTCGCGATTGGCGGCTCCTGGTACTACCCTATCGCTGGCCTTGTGATGCTCGGCGTCG CCTGGATGCTGTGGCGCAGTAAACGCGCCGCGCTTTGGCTATACGCAGCCCTGCTGCTCGGCACCATGATTTGGGGCGTC TGGGAAGTTGGTTTCGACTTCTGGGCGCTGACTCCGCGCAGCGATATTCTGGTCTTCTTCGGCATCTGGCTGATCCTGCC GTTTGTCTGGCGTCGCCTGGTCATTCCTGCCAGCGGCGCAGTTGCCGCACTGGTGGTCGCACTGCTGATTAGCGGTGGTA TCCTGACCTGGGCCGGATTTAACGATCCGCAGGAGATCAACGGCACCTTAAGCGCCGATGCCACACCTGCCGAAGCTATC TCCCCCGTTGCCGATCAGGACTGGCCTGCGTATGGCCGCAATCAGGAAGGTCAACGCTTTTCACCACTGAAGCAAATTCA CGCCGATAACGTCCACAAGCTGAAAGAAGCCTGGGTGTTCCGTACTGGCGATGTGAAGCAGCCGAACGATCCGGGTGAAA TCACCAATGAAGTGACGCCGATTAAAGTGGGCGATACCCTTTACCTGTGTACCGCTCACCAGCGCCTGTTTGCGCTTGAT GCCGCCAGCGGCAAAGAGAAATGGCATTACGATCCTGAGCTGAAAACCAACGAGTCTTTCCAGCACGTAACCTGCCGTGG CGTCTCTTATCATGAAGCCAAAGCAGAAACGGCTTCGCCGGAAGTGATGGCGGATTGCCCGCGTCGTATCATTCTTCCAG TGAATGATGGTCGCCTGATTGCGATTAACGCTGAAAACGGCAAACTGTGCGAAACCTTCGCCAATAAAGGCGTGCTCAAT CTGCAAAGCAATATGCCAGACACCAAACCGGGTCTGTATGAGCCGACTTCTCCGCCAATTATCACCGATAAAACCATCGT GATGGCCGGTTCAGTCACCGATAACTTCTCAACCCGCGAAACGTCTGGCGTGATCCGTGGTTTTGATGTCAACACCGGGG AGCTGCTGTGGGCTTTTGATCCGGGCGCGAAAGATCCGAACGCAATCCCGTCAGACGAACACACCTTTACCTTTAACTCA CCAAACTCGTGGGCACCAGCGGCCTATGACGCGAAGCTGGATCTGGTCTATCTGCCGATGGGCGTGACCACGCCGGATAT CTGGGGCGGTAACCGCACACCGGAACAGGAACGTTATGCCAGCTCGATTCTGGCGCTGAATGCCACTACCGGGAAACTGG CGTGGAGCTACCAGACCGTTCACCACGACCTGTGGGACATGGATCTTCCGGCACAGCCGACGCTGGCGGACATCACCGTT AATGGTCAGAAAGTGCCGATTATTTACGCTCCGGCGAAAACCGGTAACATTTTTGTGCTCGATCGTCGTAATGGCGAACT GGTGGTTCCGGCCCCGGAAAAACCGGTTCCCCAAGGTGCTGCCAAAGGCGATTACGTTACCCCTACTCAACCATTCTCGG AACTGAGCTTCCGTCCGACGAAAGATTTGAGCGGTGCGGATATGTGGGGAGCCACCATGTTTGACCAACTGGTGTGCCGC GTGATGTTCCACCAGATGCGCTATGAAGGCATTTTCACGCCGCCATCTGAACAGGGTACGCTGGTCTTCCCGGGTAACCT GGGGATGTTCGAATGGGGCGGGATTTCCGTTGATCCAAATCGTGAAGTGGCAATTGCCAACCCAATGGCACTGCCGTTTG TTTCGAAACTGCTCCCGCGTGGTCCTGGCAACCCGATGGAGCAGCCGAAAGATGCCAAAGGCACGGGTACGGAATCCGGC ATTCAGCCACAGTACGGTGTACCGTATGGTGTCACGCTCAACCCGTTCCTCTCACCATTTGGTCTGCCATGTAAACAGCC AGCATGGGGTTATATCTCGGCGCTGGATCTGAAAACTAATGAAGTGGTGTGGAAGAAACGTATTGGTACGCCGCAGGACA GTATGCCGTTCCCGATGCCGGTTCCGGTGCCGTTCAATATGGGTATGCCGATGCTGGGCGGGCCAATCTCCACGGCGGGT AACGTGCTGTTTATCGCCGCTACGGCAGATAACTACCTGCGCGCTTACAACATGAGCAACGGTGAAAAACTGTGGCAGGG TCGTTTACCGGCGGGTGGTCAGGCAACACCGATGACCTATGAAGTGAATGGCAAGCAGTACGTGGTGATCTCCGCAGGCG GTCACGGTTCATTTGGTACGAAGATGGGCGACTATATTGTGGCTTATGCCCTGCCGGATGATGTGAAATAA
Upstream 100 bases:
>100_bases GAATCTGTTAATAAAGCTCGAATTGTGATGACGGTCACACATGTTAAAACCTATAATTAATTGCTACTAAAATATTAATG AATTGAAATGGTGTCTCTTT
Downstream 100 bases:
>100_bases CCATAATGCCCGGAGAGATCCGGGCATATTTCCGAATACGGTCTTTTTATACCGTAAACCCTAACATCATCCCCGTATCT TCATGCTCCAGCAGATGGCA
Product: glucose dehydrogenase
Products: NA
Alternate protein names: Glucose dehydrogenase [pyrroloquinoline-quinone] [H]
Number of amino acids: Translated: 796; Mature: 795
Protein sequence:
>796_residues MAINNTASRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGV WEVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAI SPVADQDWPAYGRNQEGQRFSPLKQIHADNVHKLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALD AASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLN LQSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNS PNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITV NGQKVPIIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCR VMFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLLPRGPGNPMEQPKDAKGTGTESG IQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAG NVLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK
Sequences:
>Translated_796_residues MAINNTASRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGV WEVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAI SPVADQDWPAYGRNQEGQRFSPLKQIHADNVHKLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALD AASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLN LQSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNS PNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITV NGQKVPIIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCR VMFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLLPRGPGNPMEQPKDAKGTGTESG IQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAG NVLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK >Mature_795_residues AINNTASRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGVW EVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAIS PVADQDWPAYGRNQEGQRFSPLKQIHADNVHKLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALDA ASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNL QSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNSP NSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITVN GQKVPIIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCRV MFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLLPRGPGNPMEQPKDAKGTGTESGI QPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGN VLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK
Specific function: GDH is probably involved in energy conservation rather than in sugar metabolism [H]
COG id: COG4993
COG function: function code G; Glucose dehydrogenase
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein; Periplasmic side [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]
Homologues:
Organism=Escherichia coli, GI1786316, Length=796, Percent_Identity=99.3718592964824, Blast_Score=1624, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR017511 - InterPro: IPR019556 - InterPro: IPR019551 - InterPro: IPR018391 - InterPro: IPR002372 - InterPro: IPR011047 - InterPro: IPR001479 [H]
Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]
EC number: =1.1.5.2 [H]
Molecular weight: Translated: 86813; Mature: 86682
Theoretical pI: Translated: 5.54; Mature: 5.54
Prosite motif: PS00364 BACTERIAL_PQQ_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAINNTASRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLVMLGVAWMLWRS CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC KRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGA CCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCH VAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAISPVADQDWPAYGRNQEGQRF HHHHHHHHHHCCCEEEECCCCCHHHCCCEEECCCCCHHHHCCCCCCCCCCCCCCCCCCCC SPLKQIHADNVHKLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALD CHHHHHHCCHHHHHHHHHEEECCCCCCCCCCCHHCCCCCEEEECCEEEEEECCCEEEEEE AASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLI CCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHCCCCCCCCHHHHCCCCEEEEEECCCEEE AINAENGKLCETFANKGVLNLQSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRE EEECCCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCEECCCEEEEECCCCCCCCCCC TSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNSPNSWAPAAYDAKLDLVYLPM CCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCEECCEEEEEEEEC GVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITV CCCCCCCCCCCCCCHHHHHHHEEEEEECCCCCEEEEEEHHHHHHHCCCCCCCCCEEEEEE NGQKVPIIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPT CCCEEEEEEECCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCC KDLSGADMWGATMFDQLVCRVMFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPN CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEECCCCCEEECCCEEECCC REVAIANPMALPFVSKLLPRGPGNPMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPF CCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC GLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAG CCCCCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC NVLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGT CEEEEEECCCCEEEEECCCCCHHHHCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCC KMGDYIVAYALPDDVK CCCCEEEEEECCCCCC >Mature Secondary Structure AINNTASRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLVMLGVAWMLWRS CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC KRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGA CCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCH VAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAISPVADQDWPAYGRNQEGQRF HHHHHHHHHHCCCEEEECCCCCHHHCCCEEECCCCCHHHHCCCCCCCCCCCCCCCCCCCC SPLKQIHADNVHKLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALD CHHHHHHCCHHHHHHHHHEEECCCCCCCCCCCHHCCCCCEEEECCEEEEEECCCEEEEEE AASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLI CCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHCCCCCCCCHHHHCCCCEEEEEECCCEEE AINAENGKLCETFANKGVLNLQSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRE EEECCCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCEECCCEEEEECCCCCCCCCCC TSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNSPNSWAPAAYDAKLDLVYLPM CCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCEECCEEEEEEEEC GVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITV CCCCCCCCCCCCCCHHHHHHHEEEEEECCCCCEEEEEEHHHHHHHCCCCCCCCCEEEEEE NGQKVPIIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPT CCCEEEEEEECCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCC KDLSGADMWGATMFDQLVCRVMFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPN CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEECCCCCEEECCCEEECCC REVAIANPMALPFVSKLLPRGPGNPMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPF CCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC GLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAG CCCCCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC NVLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGT CEEEEEECCCCEEEEECCCCCHHHHCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCC KMGDYIVAYALPDDVK CCCCEEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 2228962; 8419307; 8202364; 9278503; 8509415; 8554505 [H]