Click here to switch to the map view.

The map label for this gene is nrdD [H]

Identifier: 29144731

GI number: 29144731

Start: 4631519

End: 4633657

Strand: Reverse

Name: nrdD [H]

Synonym: t4486

Alternate gene names: 29144731

Gene position: 4633657-4631519 (Counterclockwise)

Preceding gene: 29144733

Following gene: 29144730

Centisome position: 96.7

GC content: 55.12

Gene sequence:

>2139_bases
ATGACACCGCATGTGATGAAACGAGATGGCTGTAAAGTGCCATTCAAATCAGAGCGCATTAAGGAAGCCATTCTACGTGC
AGCTAAAGCAGCGGGAGTCGATGACGCAGATTACTGTGCCACCGTCGCAGAAGTCGTTAGCAGCCAAATGAACGCACGCA
GTCAGGTGGATATTAACGAGATCCAAACTGCGGTTGAAAACCAACTGATGTCCGGCCCGTACAAACAGCTTGCCCGCGCC
TACATCGAATACCGTCACGATCGTGACATTCAGCGTGAAAAGCGTGGTCGTCTGAACCAGGAAATTCGCGGCCTGGTAGA
GCAAACTAACTCCGCGTTGCTCAATGAAAACGCCAACAAAGACAGTAAAGTCATTCCCACCCAGCGCGATTTGCTGGCCG
GGATTGTCGCCAAACACTATGCCCGCCAGCACCTGTTGCCGCGTGACGTAGTACAAGCGCATGAGCGCGGCGATATCCAC
TATCACGATCTCGACTATTCGCCGTTCTTCCCGATGTTCAACTGTATGTTGATCGACCTGAAAGGCATGTTGACCCAGGG
CTTTAAGATGGGTAACGCCGAGATCGAACCGCCAAAATCTATCTCTACCGCCACTGCCGTTACCGCGCAGATTATCGCGC
AGGTCGCCAGCCATATTTATGGCGGCACCACCATTAACCGTATCGACGAAGTGCTGGCGCCGTTTGTCACCGAAAGCTAT
AACAAGCACCGCAAAACCGCCGATGAGTGGCAGATCCCGGATGCCGAAGGGTATGCGCGTTCTCGCACCGAAAAAGAGTG
CTACGACGCCTTCCAGTCGCTGGAATACGAAGTTAACACGCTGCACACCGCTAACGGCCAGACGCCTTTCGTGACCTTTG
GTTTTGGCCTCGGCACCAGTTGGGAGTCGCGTCTGATCCAGGCGTCTATTTTGCGTAACCGTATCGCCGGTCTGGGTAAA
AATCGCAAAACCGCCGTGTTCCCAAAACTGGTCTTCGCTATCCGCGATGGTTTGAACCACAAGTTTGGCGATCCGAACTA
CGACATTAAACAACTGGCGCTGGAGTGCGCGAGCAAGCGCATGTATCCGGACATTCTCAACTACGATCAGGTGGTCAAAG
TCACCGGTTCGTTCAAAACGCCAATGGGCTGCCGCAGTTTCCTCGGCGTGTGGGAGAACGAAAACGGCGAGCAGATCCAC
GACGGGCGTAACAACTTGGGCGTGATTAGCCTTAACCTGCCGCGCATCGCGCTGGAAGCAAAAGGCGACGAAACCGCATT
CTGGAAACTGCTGGATGAACGTCTGGCGCTGGCGCGGAAGGCGCTGATGACCCGTATCGCCCGCCTTGAAGGCGTGAAAG
CCCGTGTCGCGCCTATCCTGTATATGGAAGGCGCCTGCGGCGTGCGGCTGAAAGCGGACGACGACGTGTCTGAAATCTTT
AAAAATGGTCGTGCGTCCATCTCTCTGGGCTACATTGGTATCCATGAAACCATTAACGCGCTGTTCGGCGGCGAACACCT
GTACGACAGCGAGCAACTTCGCGCTAAAGGCATCGCGATTGTGGAGCGTCTGCGCCAGGCCGTGGATCAGTGGAAAGACG
AGACCGGCTACGGCTTTAGTCTGTACAGCACGCCAAGTGAAAACCTCTGTGACCGCTTCTGCCGTCTGGATACCGCCGAG
TTCGGCGTGGTGCCGGGCGTAACCGATAAAGGTTACTACACCAACAGCTTCCACCTCGACGTGGAGAAGAAGGTCAACCC
GTACGACAAAATCAGTTTCGAAGCGCCGTATCCGCCGCTGGCGAACGGGGGTTTCATTTGCTACGGCGAATACCCGAACA
TTCAGCACAACCTGAAAGCGCTGGAAGATGTCTGGGATTACAGCTATCAGCATGTACCGTATTACGGCACCAACACGCCG
ATCGATGAATGCTACGAGTGCGGCTTTACCGGCGAGTTCGAATGTACCAGTAAAGGTTTCACCTGCCCGAAATGCGGCAA
CCACGACGCCGCGCGCGTCTCGGTTACCCGTCGCGTGTGCGGTTATTTAGGCAGCCCGGACGCGCGTCCGTTTAACGCCG
GTAAGCAGGAAGAAGTGAAGCGCCGCGTGAAGCATTTAGGCAACGGGCAGATAGGTTAA

Upstream 100 bases:

>100_bases
GGGTCAGGATTGCGGGAAGTCATTGGAAAAGAGATGAATAAACCTGTTATGGCTTCCCCGGCCTCTGTGGATAACCTGTT
CTTACAAATATGGAGTGATC

Downstream 100 bases:

>100_bases
TTTCCGTTTGCAAAGACCGTAGGCCTGATAAGACGCAATCGCGTCGTCATCAGGCATCACAATGTTGCCGGATGCGGTGC
AAGCACCTTATCCGGCCTAC

Product: anaerobic ribonucleoside triphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 712; Mature: 711

Protein sequence:

>712_residues
MTPHVMKRDGCKVPFKSERIKEAILRAAKAAGVDDADYCATVAEVVSSQMNARSQVDINEIQTAVENQLMSGPYKQLARA
YIEYRHDRDIQREKRGRLNQEIRGLVEQTNSALLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPRDVVQAHERGDIH
YHDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVTESY
NKHRKTADEWQIPDAEGYARSRTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTSWESRLIQASILRNRIAGLGK
NRKTAVFPKLVFAIRDGLNHKFGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWENENGEQIH
DGRNNLGVISLNLPRIALEAKGDETAFWKLLDERLALARKALMTRIARLEGVKARVAPILYMEGACGVRLKADDDVSEIF
KNGRASISLGYIGIHETINALFGGEHLYDSEQLRAKGIAIVERLRQAVDQWKDETGYGFSLYSTPSENLCDRFCRLDTAE
FGVVPGVTDKGYYTNSFHLDVEKKVNPYDKISFEAPYPPLANGGFICYGEYPNIQHNLKALEDVWDYSYQHVPYYGTNTP
IDECYECGFTGEFECTSKGFTCPKCGNHDAARVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLGNGQIG

Sequences:

>Translated_712_residues
MTPHVMKRDGCKVPFKSERIKEAILRAAKAAGVDDADYCATVAEVVSSQMNARSQVDINEIQTAVENQLMSGPYKQLARA
YIEYRHDRDIQREKRGRLNQEIRGLVEQTNSALLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPRDVVQAHERGDIH
YHDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVTESY
NKHRKTADEWQIPDAEGYARSRTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTSWESRLIQASILRNRIAGLGK
NRKTAVFPKLVFAIRDGLNHKFGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWENENGEQIH
DGRNNLGVISLNLPRIALEAKGDETAFWKLLDERLALARKALMTRIARLEGVKARVAPILYMEGACGVRLKADDDVSEIF
KNGRASISLGYIGIHETINALFGGEHLYDSEQLRAKGIAIVERLRQAVDQWKDETGYGFSLYSTPSENLCDRFCRLDTAE
FGVVPGVTDKGYYTNSFHLDVEKKVNPYDKISFEAPYPPLANGGFICYGEYPNIQHNLKALEDVWDYSYQHVPYYGTNTP
IDECYECGFTGEFECTSKGFTCPKCGNHDAARVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLGNGQIG
>Mature_711_residues
TPHVMKRDGCKVPFKSERIKEAILRAAKAAGVDDADYCATVAEVVSSQMNARSQVDINEIQTAVENQLMSGPYKQLARAY
IEYRHDRDIQREKRGRLNQEIRGLVEQTNSALLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPRDVVQAHERGDIHY
HDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVTESYN
KHRKTADEWQIPDAEGYARSRTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTSWESRLIQASILRNRIAGLGKN
RKTAVFPKLVFAIRDGLNHKFGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWENENGEQIHD
GRNNLGVISLNLPRIALEAKGDETAFWKLLDERLALARKALMTRIARLEGVKARVAPILYMEGACGVRLKADDDVSEIFK
NGRASISLGYIGIHETINALFGGEHLYDSEQLRAKGIAIVERLRQAVDQWKDETGYGFSLYSTPSENLCDRFCRLDTAEF
GVVPGVTDKGYYTNSFHLDVEKKVNPYDKISFEAPYPPLANGGFICYGEYPNIQHNLKALEDVWDYSYQHVPYYGTNTPI
DECYECGFTGEFECTSKGFTCPKCGNHDAARVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLGNGQIG

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glycine radical domain [H]

Homologues:

Organism=Escherichia coli, GI1790686, Length=712, Percent_Identity=96.4887640449438, Blast_Score=1443, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR001150
- InterPro:   IPR019777
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF01228 Gly_radical [H]

EC number: =1.17.4.2 [H]

Molecular weight: Translated: 79931; Mature: 79800

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS51161 ATP_CONE ; PS00850 GLY_RADICAL_1 ; PS51149 GLY_RADICAL_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHVMKRDGCKVPFKSERIKEAILRAAKAAGVDDADYCATVAEVVSSQMNARSQVDINE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
IQTAVENQLMSGPYKQLARAYIEYRHDRDIQREKRGRLNQEIRGLVEQTNSALLNENANK
HHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
DSKVIPTQRDLLAGIVAKHYARQHLLPRDVVQAHERGDIHYHDLDYSPFFPMFNCMLIDL
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHH
KGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVTESY
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
NKHRKTADEWQIPDAEGYARSRTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTS
HHHCCCHHHCCCCCCCCHHHCCCHHHHHHHHHHCCHHHHEEEECCCCCCEEEEECCCCCC
WESRLIQASILRNRIAGLGKNRKTAVFPKLVFAIRDGLNHKFGDPNYDIKQLALECASKR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
MYPDILNYDQVVKVTGSFKTPMGCRSFLGVWENENGEQIHDGRNNLGVISLNLPRIALEA
CCHHHCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCHHCCCCCEEEEEECCCEEEEEC
KGDETAFWKLLDERLALARKALMTRIARLEGVKARVAPILYMEGACGVRLKADDDVSEIF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCEEEECCCCHHHHH
KNGRASISLGYIGIHETINALFGGEHLYDSEQLRAKGIAIVERLRQAVDQWKDETGYGFS
HCCCCEEEEEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
LYSTPSENLCDRFCRLDTAEFGVVPGVTDKGYYTNSFHLDVEKKVNPYDKISFEAPYPPL
EECCCCHHHHHHHHHCCCHHCCCCCCCCCCCEECCEEEEEECCCCCCCCCCCCCCCCCCC
ANGGFICYGEYPNIQHNLKALEDVWDYSYQHVPYYGTNTPIDECYECGFTGEFECTSKGF
CCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCEEECCCCC
TCPKCGNHDAARVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLGNGQIG
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TPHVMKRDGCKVPFKSERIKEAILRAAKAAGVDDADYCATVAEVVSSQMNARSQVDINE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
IQTAVENQLMSGPYKQLARAYIEYRHDRDIQREKRGRLNQEIRGLVEQTNSALLNENANK
HHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
DSKVIPTQRDLLAGIVAKHYARQHLLPRDVVQAHERGDIHYHDLDYSPFFPMFNCMLIDL
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHH
KGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVTESY
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
NKHRKTADEWQIPDAEGYARSRTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTS
HHHCCCHHHCCCCCCCCHHHCCCHHHHHHHHHHCCHHHHEEEECCCCCCEEEEECCCCCC
WESRLIQASILRNRIAGLGKNRKTAVFPKLVFAIRDGLNHKFGDPNYDIKQLALECASKR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
MYPDILNYDQVVKVTGSFKTPMGCRSFLGVWENENGEQIHDGRNNLGVISLNLPRIALEA
CCHHHCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCHHCCCCCEEEEEECCCEEEEEC
KGDETAFWKLLDERLALARKALMTRIARLEGVKARVAPILYMEGACGVRLKADDDVSEIF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCEEEECCCCHHHHH
KNGRASISLGYIGIHETINALFGGEHLYDSEQLRAKGIAIVERLRQAVDQWKDETGYGFS
HCCCCEEEEEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
LYSTPSENLCDRFCRLDTAEFGVVPGVTDKGYYTNSFHLDVEKKVNPYDKISFEAPYPPL
EECCCCHHHHHHHHHCCCHHCCCCCCCCCCCEECCEEEEEECCCCCCCCCCCCCCCCCCC
ANGGFICYGEYPNIQHNLKALEDVWDYSYQHVPYYGTNTPIDECYECGFTGEFECTSKGF
CCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCEEECCCCC
TCPKCGNHDAARVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLGNGQIG
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8421692; 7610040; 9278503; 8083158; 7852304 [H]