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The map label for this gene is zntR [H]

Identifier: 29144358

GI number: 29144358

Start: 4231759

End: 4232184

Strand: Direct

Name: zntR [H]

Synonym: t4093

Alternate gene names: 29144358

Gene position: 4231759-4232184 (Clockwise)

Preceding gene: 29144357

Following gene: 29144364

Centisome position: 88.31

GC content: 48.83

Gene sequence:

>426_bases
ATGTATCGCATTGGTGAGCTGGCAAAGCTGGCAGACGTAACGCCTGATACCATTCGCTACTATGAAAAACAGCAGATGAT
GGATCATGAGGTACGTACTGAAGGCGGGTTTCGTCTGTATACCGAAAACGATCTGCAGCGTCTCAAGTTTATTCGTTATG
CGCGGCAGTTGGGTTTCACGCTTGAGTCGATCCGCGAACTTTTATCGATCAGAATTGATCCTGAGCACCATACCTGTCAG
GAGTCAAAAAGTATTGTGCAAGAACGATTGCAGGAGGTTGAAGCCAGGATTGCGGAACTGCAAACGATGCAGCGTTCGTT
ACAAAGGCTTAATGATGCTTGTTGCGGAACGGCCCACAGTAGCGTCTATTGTTCCATTCTGGAAGCCCTGGAACAGGGGG
CCAGTGGGGCGAAATCAGTATGTTGA

Upstream 100 bases:

>100_bases
GAACTAAAACTTCGGCAGGCTGGGTTGAGTACCGATTTTTTACACGGTGAGTATGCAGAAAAACTGCTGCATAAAATCAA
CGATAATTAACGGAGCTTGT

Downstream 100 bases:

>100_bases
TTTATTGAACCGGCGGGACTACACTCGCGCCGTATAATTTATACAAACGGGAGATATTATGAGTCGTTATCAACATAAGA
AAGGGCAGATAAAGGACAAT

Product: zinc-responsive transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MYRIGELAKLADVTPDTIRYYEKQQMMDHEVRTEGGFRLYTENDLQRLKFIRYARQLGFTLESIRELLSIRIDPEHHTCQ
ESKSIVQERLQEVEARIAELQTMQRSLQRLNDACCGTAHSSVYCSILEALEQGASGAKSVC

Sequences:

>Translated_141_residues
MYRIGELAKLADVTPDTIRYYEKQQMMDHEVRTEGGFRLYTENDLQRLKFIRYARQLGFTLESIRELLSIRIDPEHHTCQ
ESKSIVQERLQEVEARIAELQTMQRSLQRLNDACCGTAHSSVYCSILEALEQGASGAKSVC
>Mature_141_residues
MYRIGELAKLADVTPDTIRYYEKQQMMDHEVRTEGGFRLYTENDLQRLKFIRYARQLGFTLESIRELLSIRIDPEHHTCQ
ESKSIVQERLQEVEARIAELQTMQRSLQRLNDACCGTAHSSVYCSILEALEQGASGAKSVC

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=141, Percent_Identity=92.9078014184397, Blast_Score=272, Evalue=5e-75,
Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=37.007874015748, Blast_Score=87, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16259; Mature: 16259

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRIGELAKLADVTPDTIRYYEKQQMMDHEVRTEGGFRLYTENDLQRLKFIRYARQLGFT
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCH
LESIRELLSIRIDPEHHTCQESKSIVQERLQEVEARIAELQTMQRSLQRLNDACCGTAHS
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SVYCSILEALEQGASGAKSVC
HHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MYRIGELAKLADVTPDTIRYYEKQQMMDHEVRTEGGFRLYTENDLQRLKFIRYARQLGFT
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCH
LESIRELLSIRIDPEHHTCQESKSIVQERLQEVEARIAELQTMQRSLQRLNDACCGTAHS
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SVYCSILEALEQGASGAKSVC
HHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]