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The map label for this gene is secY [H]

Identifier: 29144350

GI number: 29144350

Start: 4226792

End: 4228123

Strand: Direct

Name: secY [H]

Synonym: t4085

Alternate gene names: 29144350

Gene position: 4226792-4228123 (Clockwise)

Preceding gene: 29144349

Following gene: 29144351

Centisome position: 88.21

GC content: 49.55

Gene sequence:

>1332_bases
ATGGCTAAACAACCGGGATTAGATTTTCAAAGTGCCAAAGGTGGCTTAGGTGAGCTGAAACGCAGACTGCTGTTTGTTAT
CGGCGCGCTGATTGTGTTCCGTATTGGCTCTTTTATTCCGATCCCTGGTATTGATGCCGCTGTACTTGCCAAACTGCTTG
AGCAACAGCGAGGCACCATCATTGAAATGTTTAACATGTTCTCTGGTGGTGCTCTCAGCCGTGCTTCTATCTTTGCCCTG
GGGATCATGCCGTATATTTCGGCGTCGATCATTATCCAGCTGTTGACGGTGGTTCATCCAACGCTCGCAGAAATTAAGAA
AGAAGGGGAGTCTGGTCGTCGTAAGATCAGCCAGTACACCCGTTACGGTACTCTGGTGCTGGCGATATTCCAGTCGATCG
GTATTGCTACCGGTTTGCCGAATATGCCTGGTATGCAGGGCCTGGTGATGAATCCAGGCTTTGCATTCTATTTCACCGCT
GTTGTAAGTCTGGTTACAGGGACCATGTTCCTGATGTGGCTCGGCGAACAGATTACTGAGCGCGGTATCGGTAACGGTAT
CTCAATCATCATCTTCGCTGGTATCGTTGCGGGACTCCCGCCAGCCATTGCCCATACTATCGAGCAAGCGCGTCAAGGCG
ACCTGCACTTCCTCGTGTTGCTGTTGGTTGCAGTATTAGTATTTGCAGTGACGTTCTTTGTAGTATTCGTTGAACGTGGT
CAACGCCGTATTGTGGTAAACTACGCCAAACGTCAGCAAGGTCGTCGTGTCTATGCTGCACAGAGCACACATTTACCGCT
GAAAGTGAATATGGCGGGGGTAATCCCGGCAATCTTCGCTTCCAGTATTATTCTGTTCCCGGCGACCATAGCGTCATGGT
TCGGGGGCGGTACTGGTTGGAACTGGCTGACAACAATTTCGCTGTATTTGCAGCCTGGGCAACCGCTTTATGTGTTACTC
TATGCGTCTGCAATCATCTTCTTCTGTTTCTTCTACACGGCGTTGGTTTTCAACCCGCGTGAAACAGCAGATAACCTGAA
GAAGTCCGGTGCATTTGTACCAGGAATTCGTCCGGGAGAGCAAACGGCGAAGTATATCGATAAAGTAATGACCCACCTGA
CCCTGGTTGGTGCGCTGTATATTACCTTTATCTGCCTGATCCCGGAGTTCATGCGTGATGCAATGAAAGTGCCGTTCTAC
TTCGGTGGGACCTCACTGCTTATCGTTGTTGTCGTGATTATGGACTTTATGGCTCAAGTGCAAACTCTGATGATGTCCAG
TCAGTATGAGTCTGCATTGAAGAAGGCGAACCTGAAAGGCTACGGCCGTTAA

Upstream 100 bases:

>100_bases
GAAGTCACTACTCCGGTAACTGTTCGTGGCCTGCGTGTTACTAAAGGCGCTCGTGCTGCTATCGAAGCTGCTGGCGGTAA
AATCGAGGAATAAGTAGCAG

Downstream 100 bases:

>100_bases
TTGGTCGCCTGAGAAGTTACGGAGAGTAAAAATGAAAGTTCGTGCTTCCGTCAAGAAATTATGCCGTAACTGCAAAATCG
TTAAGCGTGATGGTGTCATC

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGIDAAVLAKLLEQQRGTIIEMFNMFSGGALSRASIFAL
GIMPYISASIIIQLLTVVHPTLAEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVMNPGFAFYFTA
VVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFLVLLLVAVLVFAVTFFVVFVERG
QRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLL
YASAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTHLTLVGALYITFICLIPEFMRDAMKVPFY
FGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYGR

Sequences:

>Translated_443_residues
MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGIDAAVLAKLLEQQRGTIIEMFNMFSGGALSRASIFAL
GIMPYISASIIIQLLTVVHPTLAEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVMNPGFAFYFTA
VVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFLVLLLVAVLVFAVTFFVVFVERG
QRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLL
YASAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTHLTLVGALYITFICLIPEFMRDAMKVPFY
FGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYGR
>Mature_442_residues
AKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGIDAAVLAKLLEQQRGTIIEMFNMFSGGALSRASIFALG
IMPYISASIIIQLLTVVHPTLAEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVMNPGFAFYFTAV
VSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFLVLLLVAVLVFAVTFFVVFVERGQ
RRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLLY
ASAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTHLTLVGALYITFICLIPEFMRDAMKVPFYF
GGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYGR

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=443, Percent_Identity=99.548532731377, Blast_Score=884, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 48512; Mature: 48380

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGIDAAVLAKLLEQQRGTI
CCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHH
IEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTLAEIKKEGESGRRKISQYT
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RYGTLVLAIFQSIGIATGLPNMPGMQGLVMNPGFAFYFTAVVSLVTGTMFLMWLGEQITE
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFLVLLLVAVLVFAVTFFVVFVERG
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
QRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGW
CCEEEEEHHHHHCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGE
HHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCH
QTAKYIDKVMTHLTLVGALYITFICLIPEFMRDAMKVPFYFGGTSLLIVVVVIMDFMAQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHH
QTLMMSSQYESALKKANLKGYGR
HHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGIDAAVLAKLLEQQRGTI
CCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHH
IEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTLAEIKKEGESGRRKISQYT
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RYGTLVLAIFQSIGIATGLPNMPGMQGLVMNPGFAFYFTAVVSLVTGTMFLMWLGEQITE
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFLVLLLVAVLVFAVTFFVVFVERG
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
QRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGW
CCEEEEEHHHHHCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGE
HHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCH
QTAKYIDKVMTHLTLVGALYITFICLIPEFMRDAMKVPFYFGGTSLLIVVVVIMDFMAQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHH
QTLMMSSQYESALKKANLKGYGR
HHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]