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The map label for this gene is yheS [H]

Identifier: 29144311

GI number: 29144311

Start: 4202412

End: 4204319

Strand: Reverse

Name: yheS [H]

Synonym: t4046

Alternate gene names: 29144311

Gene position: 4204319-4202412 (Counterclockwise)

Preceding gene: 29144316

Following gene: 29144308

Centisome position: 87.74

GC content: 57.65

Gene sequence:

>1908_bases
ATGATTGTTTTCTCCTCGTTACAAATTCGTCGCGGCGTGCGCGTCCTACTGGACAATGCCTCGGCTACCATTAATCCAGG
CCAGAAAGTCGGCCTGGTGGGTAAAAACGGCTGCGGTAAATCTACCCTGCTGGCATTGCTAAAAAATGAAATCAGCGCCG
ATGCCGGGAGTTTTACCCTGCCCGGAACCTGGCAATTAGCGTGGGTGAATCAGGAAACACCTGCGTTGCCTCAGCCAGCG
ATTGAGTATGTCATTGACGGCGACCGTGAATACCGGCATCTGGAGGCGCAGCTTAACGACGCCAACGAACGTAACGACGG
GCATGCTATCGCCTCCATACACGGTAAGCTGGACGCCATCGACGCATGGACCGTTCGCTCGCGCGCCGCCAGCCTGTTAC
ACGGCCTCGGCTTCTCTAACGATCAGCTGGAACGTCCGGTCAGCGACTTTTCCGGCGGCTGGCGGATGCGCCTTAATCTG
GCCCAGGCGCTGATTTGCCGTTCCGATTTACTGCTGCTCGACGAACCGACCAACCACCTCGATCTGGATGCCGTTATCTG
GCTGGAAAAATGGCTGAAGAGCTATCCAGGCACCCTGATTCTGATCTCCCACGATCGCGATTTTCTTGACCCGATAGTGG
ATAAAATTATCCATATCGAACAGCAGACTCTGTTCGAGTACACCGGTAACTACAGCGCGTTTGAAGTTCAGCGCGCCACG
CGCCTGGCGCAGCAGCAGGCGATGTATGAGAGTCAGCAGGAGCGTGTGGCGCATCTGCAAAGCTACATCGACCGTTTCCG
CGCCAAGGCCACCAAGGCCAAGCAGGCGCAAAGCCGTATCAAGATGCTGGAGCGTATGGAGTTGATTGCGCCGGCTCATG
TCGACAACCCGTTCCATTTCAGCTTCCGCGCGCCGGAAAGCCTGCCGAACCCGCTGCTGAAGATGGAAAAAGTCAGCGCA
GGTTATGGCGATCGCATCATTCTGGAATCCATCAAGCTGAACCTGGTGCCCGGCTCGCGTATCGGCCTGCTGGGCCGCAA
CGGCGCGGGGAAATCGACGCTGATCAAGCTGCTGGCGGGCGAACTGGAACCGTTGCACGGTGAAATCGGCCTCGCCAAAG
GCATTAAGCTCGGCTACTTCGCCCAGCACCAACTGGAGTTCCTGCGCGCCGATGAATCCCCGCTGCAGCATATGGCGCGT
CTGGCGCCGCAGGAACTGGAGCAGAAGCTGCGCGACTATCTCGGCGGCTTCGGTTTCCAGGGCGACAAAGTAACGGAAGA
GACGCAACGTTTCTCCGGCGGCGAGAAAGCGCGCCTGGTACTGGCGCTGATCGTCTGGCAGCGTCCAAATCTGCTACTGC
TCGATGAACCAACCAACCACCTGGATCTCGACATGCGTCAGGCGCTCACCGAAGCGCTGATTGATTTCGAAGGCGCATTG
GTCGTCGTGTCGCACGACCGCCACCTGATTCGCTCCACCACCGACGACCTCTATCTGGTTCACGACAAAAAGGTCGAACC
GTTCGACGGCGACCTGGAGGATTATCAGCAGTGGCTGAGCGACGTGCAGAAGCAGGAAAACCAGGCCGACGACGCACCGA
AGGAAAACAACGCCAACAGCGCTCAGTCACGCAAAGATCAGAAGCGTCGCGAAGCCGAGCTACGCACTCTAACGCAGCCG
CTGCGTAAAGAGATTACCCGTCTGGAAAAAGAGATGGAAAAGCTCAACGCCCAACTGGCGCAGGCGGAAGAGAAGCTTGG
CGACAGCAGCCTGTATGACCCAAGCCGTAAAGCGGAGATGACCGAGTGTCTGCAACTGCAGGCCAGCGCCAAATCCGGGC
TGGAAGAATGTGAAATGGCATGGCTTGAGGCGCAGGAGCAGCTTGAGCAGATGATGCAGAACGACTAA

Upstream 100 bases:

>100_bases
GTTGTTGTTTTGAGCTACCATTGCGCTCCAGCGCGGCGGTACGCCCGAATATTACATTATCATAATGATAAATTAACATA
GTCTGAACATACGGCGCCTT

Downstream 100 bases:

>100_bases
GAGCCTATCCCATTAGGCTATTTTATTCGCCATTTTAGGGCCGGGCAGTGCTCGAAATCCTCACGGTTTCTGCGCGCTGT
CCGGCCCCAAACTGGCTTCA

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MIVFSSLQIRRGVRVLLDNASATINPGQKVGLVGKNGCGKSTLLALLKNEISADAGSFTLPGTWQLAWVNQETPALPQPA
IEYVIDGDREYRHLEAQLNDANERNDGHAIASIHGKLDAIDAWTVRSRAASLLHGLGFSNDQLERPVSDFSGGWRMRLNL
AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYPGTLILISHDRDFLDPIVDKIIHIEQQTLFEYTGNYSAFEVQRAT
RLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQAQSRIKMLERMELIAPAHVDNPFHFSFRAPESLPNPLLKMEKVSA
GYGDRIILESIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELEPLHGEIGLAKGIKLGYFAQHQLEFLRADESPLQHMAR
LAPQELEQKLRDYLGGFGFQGDKVTEETQRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
VVVSHDRHLIRSTTDDLYLVHDKKVEPFDGDLEDYQQWLSDVQKQENQADDAPKENNANSAQSRKDQKRREAELRTLTQP
LRKEITRLEKEMEKLNAQLAQAEEKLGDSSLYDPSRKAEMTECLQLQASAKSGLEECEMAWLEAQEQLEQMMQND

Sequences:

>Translated_635_residues
MIVFSSLQIRRGVRVLLDNASATINPGQKVGLVGKNGCGKSTLLALLKNEISADAGSFTLPGTWQLAWVNQETPALPQPA
IEYVIDGDREYRHLEAQLNDANERNDGHAIASIHGKLDAIDAWTVRSRAASLLHGLGFSNDQLERPVSDFSGGWRMRLNL
AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYPGTLILISHDRDFLDPIVDKIIHIEQQTLFEYTGNYSAFEVQRAT
RLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQAQSRIKMLERMELIAPAHVDNPFHFSFRAPESLPNPLLKMEKVSA
GYGDRIILESIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELEPLHGEIGLAKGIKLGYFAQHQLEFLRADESPLQHMAR
LAPQELEQKLRDYLGGFGFQGDKVTEETQRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
VVVSHDRHLIRSTTDDLYLVHDKKVEPFDGDLEDYQQWLSDVQKQENQADDAPKENNANSAQSRKDQKRREAELRTLTQP
LRKEITRLEKEMEKLNAQLAQAEEKLGDSSLYDPSRKAEMTECLQLQASAKSGLEECEMAWLEAQEQLEQMMQND
>Mature_635_residues
MIVFSSLQIRRGVRVLLDNASATINPGQKVGLVGKNGCGKSTLLALLKNEISADAGSFTLPGTWQLAWVNQETPALPQPA
IEYVIDGDREYRHLEAQLNDANERNDGHAIASIHGKLDAIDAWTVRSRAASLLHGLGFSNDQLERPVSDFSGGWRMRLNL
AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYPGTLILISHDRDFLDPIVDKIIHIEQQTLFEYTGNYSAFEVQRAT
RLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQAQSRIKMLERMELIAPAHVDNPFHFSFRAPESLPNPLLKMEKVSA
GYGDRIILESIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELEPLHGEIGLAKGIKLGYFAQHQLEFLRADESPLQHMAR
LAPQELEQKLRDYLGGFGFQGDKVTEETQRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
VVVSHDRHLIRSTTDDLYLVHDKKVEPFDGDLEDYQQWLSDVQKQENQADDAPKENNANSAQSRKDQKRREAELRTLTQP
LRKEITRLEKEMEKLNAQLAQAEEKLGDSSLYDPSRKAEMTECLQLQASAKSGLEECEMAWLEAQEQLEQMMQND

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=537, Percent_Identity=37.6163873370577, Blast_Score=361, Evalue=1e-99,
Organism=Homo sapiens, GI10947137, Length=513, Percent_Identity=36.4522417153996, Blast_Score=313, Evalue=3e-85,
Organism=Homo sapiens, GI27881506, Length=513, Percent_Identity=36.4522417153996, Blast_Score=313, Evalue=3e-85,
Organism=Homo sapiens, GI69354671, Length=525, Percent_Identity=35.4285714285714, Blast_Score=276, Evalue=5e-74,
Organism=Homo sapiens, GI10947135, Length=525, Percent_Identity=35.4285714285714, Blast_Score=276, Evalue=5e-74,
Organism=Escherichia coli, GI1789751, Length=632, Percent_Identity=93.3544303797468, Blast_Score=1217, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=529, Percent_Identity=33.2703213610586, Blast_Score=300, Evalue=2e-82,
Organism=Escherichia coli, GI1787182, Length=627, Percent_Identity=28.7081339712919, Blast_Score=226, Evalue=5e-60,
Organism=Escherichia coli, GI2367384, Length=531, Percent_Identity=30.1318267419962, Blast_Score=225, Evalue=9e-60,
Organism=Escherichia coli, GI1788165, Length=191, Percent_Identity=34.5549738219895, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790190, Length=528, Percent_Identity=23.2954545454545, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87081782, Length=502, Percent_Identity=24.9003984063745, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081791, Length=204, Percent_Identity=27.9411764705882, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787164, Length=216, Percent_Identity=28.2407407407407, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787758, Length=205, Percent_Identity=25.3658536585366, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788506, Length=230, Percent_Identity=27.8260869565217, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI48994997, Length=221, Percent_Identity=25.3393665158371, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1789586, Length=218, Percent_Identity=27.9816513761468, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87081709, Length=213, Percent_Identity=21.5962441314554, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787500, Length=223, Percent_Identity=26.9058295964126, Blast_Score=63, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=530, Percent_Identity=37.9245283018868, Blast_Score=358, Evalue=6e-99,
Organism=Caenorhabditis elegans, GI17555318, Length=524, Percent_Identity=35.4961832061069, Blast_Score=327, Evalue=1e-89,
Organism=Caenorhabditis elegans, GI17559834, Length=547, Percent_Identity=34.1864716636197, Blast_Score=312, Evalue=4e-85,
Organism=Caenorhabditis elegans, GI71996809, Length=204, Percent_Identity=31.8627450980392, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193211015, Length=184, Percent_Identity=32.6086956521739, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193211017, Length=184, Percent_Identity=32.6086956521739, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17556528, Length=295, Percent_Identity=23.0508474576271, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=533, Percent_Identity=35.6472795497186, Blast_Score=343, Evalue=5e-95,
Organism=Saccharomyces cerevisiae, GI6320874, Length=536, Percent_Identity=35.2611940298507, Blast_Score=318, Evalue=2e-87,
Organism=Saccharomyces cerevisiae, GI6325030, Length=438, Percent_Identity=29.4520547945205, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6324314, Length=390, Percent_Identity=28.2051282051282, Blast_Score=144, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6323278, Length=391, Percent_Identity=28.1329923273657, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24666836, Length=517, Percent_Identity=38.2978723404255, Blast_Score=376, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24642252, Length=523, Percent_Identity=37.8585086042065, Blast_Score=350, Evalue=1e-96,
Organism=Drosophila melanogaster, GI18859989, Length=523, Percent_Identity=37.8585086042065, Blast_Score=350, Evalue=1e-96,
Organism=Drosophila melanogaster, GI24641342, Length=532, Percent_Identity=35.7142857142857, Blast_Score=310, Evalue=2e-84,
Organism=Drosophila melanogaster, GI24661270, Length=191, Percent_Identity=28.7958115183246, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355589, Length=191, Percent_Identity=28.7958115183246, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221500365, Length=164, Percent_Identity=31.0975609756098, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI116007184, Length=164, Percent_Identity=31.0975609756098, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71656; Mature: 71656

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVFSSLQIRRGVRVLLDNASATINPGQKVGLVGKNGCGKSTLLALLKNEISADAGSFTL
CEEECCHHHHCCCEEEEECCCCEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEC
PGTWQLAWVNQETPALPQPAIEYVIDGDREYRHLEAQLNDANERNDGHAIASIHGKLDAI
CCCEEEEEECCCCCCCCCHHHHHEECCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCH
DAWTVRSRAASLLHGLGFSNDQLERPVSDFSGGWRMRLNLAQALICRSDLLLLDEPTNHL
HHHHHHHHHHHHHHHCCCCCHHHHCCHHHCCCCEEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAVIWLEKWLKSYPGTLILISHDRDFLDPIVDKIIHIEQQTLFEYTGNYSAFEVQRAT
CHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQAQSRIKMLERMELIAPAHVDNPFHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
SFRAPESLPNPLLKMEKVSAGYGDRIILESIKLNLVPGSRIGLLGRNGAGKSTLIKLLAG
EEECCCCCCCHHHHHHHHCCCCCCEEEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHH
ELEPLHGEIGLAKGIKLGYFAQHQLEFLRADESPLQHMARLAPQELEQKLRDYLGGFGFQ
CCCCCCCCCCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCC
GDKVTEETQRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
CCCHHHHHHHCCCCCHHHHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
VVVSHDRHLIRSTTDDLYLVHDKKVEPFDGDLEDYQQWLSDVQKQENQADDAPKENNANS
EEEECCCHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
AQSRKDQKRREAELRTLTQPLRKEITRLEKEMEKLNAQLAQAEEKLGDSSLYDPSRKAEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
TECLQLQASAKSGLEECEMAWLEAQEQLEQMMQND
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIVFSSLQIRRGVRVLLDNASATINPGQKVGLVGKNGCGKSTLLALLKNEISADAGSFTL
CEEECCHHHHCCCEEEEECCCCEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEC
PGTWQLAWVNQETPALPQPAIEYVIDGDREYRHLEAQLNDANERNDGHAIASIHGKLDAI
CCCEEEEEECCCCCCCCCHHHHHEECCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCH
DAWTVRSRAASLLHGLGFSNDQLERPVSDFSGGWRMRLNLAQALICRSDLLLLDEPTNHL
HHHHHHHHHHHHHHHCCCCCHHHHCCHHHCCCCEEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAVIWLEKWLKSYPGTLILISHDRDFLDPIVDKIIHIEQQTLFEYTGNYSAFEVQRAT
CHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQAQSRIKMLERMELIAPAHVDNPFHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
SFRAPESLPNPLLKMEKVSAGYGDRIILESIKLNLVPGSRIGLLGRNGAGKSTLIKLLAG
EEECCCCCCCHHHHHHHHCCCCCCEEEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHH
ELEPLHGEIGLAKGIKLGYFAQHQLEFLRADESPLQHMARLAPQELEQKLRDYLGGFGFQ
CCCCCCCCCCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCC
GDKVTEETQRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
CCCHHHHHHHCCCCCHHHHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
VVVSHDRHLIRSTTDDLYLVHDKKVEPFDGDLEDYQQWLSDVQKQENQADDAPKENNANS
EEEECCCHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
AQSRKDQKRREAELRTLTQPLRKEITRLEKEMEKLNAQLAQAEEKLGDSSLYDPSRKAEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
TECLQLQASAKSGLEECEMAWLEAQEQLEQMMQND
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]