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The map label for this gene is malP [H]

Identifier: 29144260

GI number: 29144260

Start: 4138917

End: 4141310

Strand: Direct

Name: malP [H]

Synonym: t3992

Alternate gene names: 29144260

Gene position: 4138917-4141310 (Clockwise)

Preceding gene: 29144258

Following gene: 29144261

Centisome position: 86.37

GC content: 55.18

Gene sequence:

>2394_bases
ATGTCACAGCCAACCTTCAATAAAGATCAATTCCAGGCCGCCCTGACGCGTCAGTGGCAGCGTTTCGGTTTACTGTCGGC
GTCCGACATGACGCCTCGTCAGTGGTGGCAGGCCGTTAGCGGCGCGCTGGCGGAATTACTGAGCGCGCAACCGGTAGCGC
AGCCGACGAAAGGCCAGCGTCATGTGAACTACATTTCGATGGAATTTTTGATTGGCCGCCTGACGGGAAATAACCTGTTA
AATCTGGGGTGGTACCAGGACGTTAGCGATGTGCTGAAAGCGCACGATATTAATCTGACCGATCTGCTGGAAGAGGAAGT
CGATCCGGCGCTCGGCAACGGTGGTCTGGGACGTCTGGCCGCCTGCTTCCTCGATTCGATGGCCACCGTCGGGCAGTCCG
CTACGGGCTATGGTCTGAACTACCAGTATGGGCTGTTCCGTCAGTCATTTGTTGAAGGCAAGCAGATGGAAGCGCCGGAT
GACTGGCATCGCGGCAGCTATCCGTGGTTCCGCCACAACGAGGCGCTGGACGTCCAGGTTGGAATCGGCGGTAAAGTCAC
CAAAGAAGGGCGCTGGAAACCAGGTTTTGTGATTACAGGCCAGTCCTGGGATCTGCCGGTGTTAGGCTATCGTAACGGCG
TCGCGCAACCGCTGCGTTTGTGGCAGGCGACCCACGCGCATCCGTTTGATCTGACCAAATTCAACGACGGCGCTTTCCTG
CGGGCGGAACAGCAGGGTATCGATGCGGAAAAACTGACGAAGGTGCTTTATCCCAACGATAACCACACGGCGGGCAAAAA
ACTGCGCCTGATGCAGCAATACTTCCAGTGCGCCTGCTCGGTAGCGGATATTCTGCGCCGCCATCATCTGGCCGGACGCA
AGCTGCATGAGCTGGCGGATTATGAGGTCATTCAGCTAAATGATACCCACCCGACTATTGCCATCCCTGAACTGCTGCGC
GTATTGCTGGATGAACACCAGATGAGCTGGGATGACGCCTGGGCTATCACCAGCAAAACCTTCGCCTACACCAACCACAC
CCTGATGCCAGAAGCGCTGGAGTGCTGGGATGAGAGGTTAATCAAAGCGCTGTTGCCGCGTCATATGCAGATTATCAAGC
AGATTAACGATCGCTTTAAGGCGCTGGTCGATAACACCTGGCCTGGCGATAAGCAGGTATGGGCAAAACTGGCGGTGGTG
CATGACCGTCAGGTGCGCATGGCCAATATGTGCGTGGTCAGCGGCTTTGCGGTCAACGGTGTGGCGGCGCTGCACTCCGA
TCTGGTGGTGAAAGATCTGTTCCCGGAATATCACCAGCTTTGGCCGAACAAATTCCACAATGTCACCAACGGCATTACAC
CGCGTCGCTGGATTAAACAGTGCAATCCGCAGCTTGCGGCGTTGCTGGATAAAACGCTGAAAAAAGAGTGGGCTAACGAT
CTCGACCAGTTGATCAACCTCGAAAAATACGCTGACGACGCCACATTCCGTCAACAATATCGCGACATCAAACGGGCGAA
CAAAGAACGGCTGGTGAAATTCATCCAGGCCCGTACCGGGATTGAGATTTCGAGCCATGCGATTTTTGATATTCAGATCA
AACGCCTGCACGAGTACAAGCGTCAGCATCTGAATCTGTTGCATATTCTGGCGCTGTACAAAGAGATCCGCGAAAACCCG
CAGGCTGACCGCGTACCGCGCGTATTCCTGTTTGGCGCGAAGGCGGCGCCGGGCTATTACCTGGCGAAGAACATCATTTT
TGCTATCAATAAGGTTGCGGAAGCCATTAATAACGACCCGGCGGTGGGTGACAAGCTGAAGGTGGTTTTCCTGCCGGATT
ACTGCGTCTCGGCGGCGGAAATGCTCATTCCGGCGGCGGATATTTCCGAGCAAATTTCTACTGCCGGGAAAGAGGCGTCC
GGCACCGGCAACATGAAACTGGCGCTGAACGGGGCGTTGACAGTGGGAACGCTGGACGGCGCTAACGTTGAAATCGCTGA
AAAGGTGGGTGAAGAGAATATCTTTATCTTTGGCCATACTGTGGAAGAGGTCAAGGCGCTCAAAGCCAAAGGCTACGATC
CGGTGAAATGGCGTAAAAAAGACAAAGTGCTGGATGCGGTACTAAAAGAGCTGGAAAGCGGTCAATACAGCGATGGCGAT
AAACATGCCTTTGACCAGATGCTGCATAGCCTCGGCAAACAGGGGGGCGATCCGTACCTGGTCATGGCGGACTTCGCCGC
TTATGTCGAGGCGCAAAAGCAGGTGGATGCGCTGTATCGCGACCAGGAAGCGTGGACGCGCGCCGCGATCCTCAATACCG
CGCGCTGCGGTATGTTCAGTTCCGATCGCTCTATTCGCGATTATCAGGCCCGTATCTGGCAGGCAAAACGCTAA

Upstream 100 bases:

>100_bases
CTCCTCCTCCCTCCCTAATCAGTGCCGGGAGGAGGAAGGTCAACATCGAGCCTGGCAAACTAGCGATAACGTTGTTTTAT
TACCCGAGGACGGATTTCCT

Downstream 100 bases:

>100_bases
GGGAGCGCGATGGAAAATAAACGTCTCGATAGTGCCGCGCTGGCGGCGGGGATCAGCCCCAGTTACATCAATGCTCATGG
CAAACCGCAGTCTATTGGCG

Product: maltodextrin phosphorylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 797; Mature: 796

Protein sequence:

>797_residues
MSQPTFNKDQFQAALTRQWQRFGLLSASDMTPRQWWQAVSGALAELLSAQPVAQPTKGQRHVNYISMEFLIGRLTGNNLL
NLGWYQDVSDVLKAHDINLTDLLEEEVDPALGNGGLGRLAACFLDSMATVGQSATGYGLNYQYGLFRQSFVEGKQMEAPD
DWHRGSYPWFRHNEALDVQVGIGGKVTKEGRWKPGFVITGQSWDLPVLGYRNGVAQPLRLWQATHAHPFDLTKFNDGAFL
RAEQQGIDAEKLTKVLYPNDNHTAGKKLRLMQQYFQCACSVADILRRHHLAGRKLHELADYEVIQLNDTHPTIAIPELLR
VLLDEHQMSWDDAWAITSKTFAYTNHTLMPEALECWDERLIKALLPRHMQIIKQINDRFKALVDNTWPGDKQVWAKLAVV
HDRQVRMANMCVVSGFAVNGVAALHSDLVVKDLFPEYHQLWPNKFHNVTNGITPRRWIKQCNPQLAALLDKTLKKEWAND
LDQLINLEKYADDATFRQQYRDIKRANKERLVKFIQARTGIEISSHAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENP
QADRVPRVFLFGAKAAPGYYLAKNIIFAINKVAEAINNDPAVGDKLKVVFLPDYCVSAAEMLIPAADISEQISTAGKEAS
GTGNMKLALNGALTVGTLDGANVEIAEKVGEENIFIFGHTVEEVKALKAKGYDPVKWRKKDKVLDAVLKELESGQYSDGD
KHAFDQMLHSLGKQGGDPYLVMADFAAYVEAQKQVDALYRDQEAWTRAAILNTARCGMFSSDRSIRDYQARIWQAKR

Sequences:

>Translated_797_residues
MSQPTFNKDQFQAALTRQWQRFGLLSASDMTPRQWWQAVSGALAELLSAQPVAQPTKGQRHVNYISMEFLIGRLTGNNLL
NLGWYQDVSDVLKAHDINLTDLLEEEVDPALGNGGLGRLAACFLDSMATVGQSATGYGLNYQYGLFRQSFVEGKQMEAPD
DWHRGSYPWFRHNEALDVQVGIGGKVTKEGRWKPGFVITGQSWDLPVLGYRNGVAQPLRLWQATHAHPFDLTKFNDGAFL
RAEQQGIDAEKLTKVLYPNDNHTAGKKLRLMQQYFQCACSVADILRRHHLAGRKLHELADYEVIQLNDTHPTIAIPELLR
VLLDEHQMSWDDAWAITSKTFAYTNHTLMPEALECWDERLIKALLPRHMQIIKQINDRFKALVDNTWPGDKQVWAKLAVV
HDRQVRMANMCVVSGFAVNGVAALHSDLVVKDLFPEYHQLWPNKFHNVTNGITPRRWIKQCNPQLAALLDKTLKKEWAND
LDQLINLEKYADDATFRQQYRDIKRANKERLVKFIQARTGIEISSHAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENP
QADRVPRVFLFGAKAAPGYYLAKNIIFAINKVAEAINNDPAVGDKLKVVFLPDYCVSAAEMLIPAADISEQISTAGKEAS
GTGNMKLALNGALTVGTLDGANVEIAEKVGEENIFIFGHTVEEVKALKAKGYDPVKWRKKDKVLDAVLKELESGQYSDGD
KHAFDQMLHSLGKQGGDPYLVMADFAAYVEAQKQVDALYRDQEAWTRAAILNTARCGMFSSDRSIRDYQARIWQAKR
>Mature_796_residues
SQPTFNKDQFQAALTRQWQRFGLLSASDMTPRQWWQAVSGALAELLSAQPVAQPTKGQRHVNYISMEFLIGRLTGNNLLN
LGWYQDVSDVLKAHDINLTDLLEEEVDPALGNGGLGRLAACFLDSMATVGQSATGYGLNYQYGLFRQSFVEGKQMEAPDD
WHRGSYPWFRHNEALDVQVGIGGKVTKEGRWKPGFVITGQSWDLPVLGYRNGVAQPLRLWQATHAHPFDLTKFNDGAFLR
AEQQGIDAEKLTKVLYPNDNHTAGKKLRLMQQYFQCACSVADILRRHHLAGRKLHELADYEVIQLNDTHPTIAIPELLRV
LLDEHQMSWDDAWAITSKTFAYTNHTLMPEALECWDERLIKALLPRHMQIIKQINDRFKALVDNTWPGDKQVWAKLAVVH
DRQVRMANMCVVSGFAVNGVAALHSDLVVKDLFPEYHQLWPNKFHNVTNGITPRRWIKQCNPQLAALLDKTLKKEWANDL
DQLINLEKYADDATFRQQYRDIKRANKERLVKFIQARTGIEISSHAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENPQ
ADRVPRVFLFGAKAAPGYYLAKNIIFAINKVAEAINNDPAVGDKLKVVFLPDYCVSAAEMLIPAADISEQISTAGKEASG
TGNMKLALNGALTVGTLDGANVEIAEKVGEENIFIFGHTVEEVKALKAKGYDPVKWRKKDKVLDAVLKELESGQYSDGDK
HAFDQMLHSLGKQGGDPYLVMADFAAYVEAQKQVDALYRDQEAWTRAAILNTARCGMFSSDRSIRDYQARIWQAKR

Specific function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties [

COG id: COG0058

COG function: function code G; Glucan phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycogen phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI5032009, Length=781, Percent_Identity=43.4058898847631, Blast_Score=639, Evalue=0.0,
Organism=Homo sapiens, GI71037379, Length=754, Percent_Identity=43.7665782493369, Blast_Score=624, Evalue=1e-178,
Organism=Homo sapiens, GI21361370, Length=785, Percent_Identity=43.312101910828, Blast_Score=619, Evalue=1e-177,
Organism=Homo sapiens, GI255653002, Length=691, Percent_Identity=44.1389290882779, Blast_Score=612, Evalue=1e-175,
Organism=Homo sapiens, GI257900462, Length=655, Percent_Identity=44.5801526717557, Blast_Score=580, Evalue=1e-165,
Organism=Escherichia coli, GI48994936, Length=797, Percent_Identity=90.2132998745295, Blast_Score=1515, Evalue=0.0,
Organism=Escherichia coli, GI2367228, Length=765, Percent_Identity=47.4509803921569, Blast_Score=704, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32566204, Length=754, Percent_Identity=46.684350132626, Blast_Score=692, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17564550, Length=754, Percent_Identity=46.684350132626, Blast_Score=692, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325418, Length=789, Percent_Identity=43.8529784537389, Blast_Score=594, Evalue=1e-170,
Organism=Drosophila melanogaster, GI78706832, Length=751, Percent_Identity=45.4061251664447, Blast_Score=655, Evalue=0.0,
Organism=Drosophila melanogaster, GI24581010, Length=751, Percent_Identity=45.4061251664447, Blast_Score=655, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011833
- InterPro:   IPR000811 [H]

Pfam domain/function: PF00343 Phosphorylase [H]

EC number: =2.4.1.1 [H]

Molecular weight: Translated: 90228; Mature: 90097

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS00102 PHOSPHORYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPTFNKDQFQAALTRQWQRFGLLSASDMTPRQWWQAVSGALAELLSAQPVAQPTKGQR
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
HVNYISMEFLIGRLTGNNLLNLGWYQDVSDVLKAHDINLTDLLEEEVDPALGNGGLGRLA
HHHEEEHHHHHHHCCCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHH
ACFLDSMATVGQSATGYGLNYQYGLFRQSFVEGKQMEAPDDWHRGSYPWFRHNEALDVQV
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCEEEEEE
GIGGKVTKEGRWKPGFVITGQSWDLPVLGYRNGVAQPLRLWQATHAHPFDLTKFNDGAFL
CCCCEECCCCCCCCCEEEECCCCCCCEECCCCCCHHHHHHHHHCCCCCCCCEEECCCCEE
RAEQQGIDAEKLTKVLYPNDNHTAGKKLRLMQQYFQCACSVADILRRHHLAGRKLHELAD
EEHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCC
YEVIQLNDTHPTIAIPELLRVLLDEHQMSWDDAWAITSKTFAYTNHTLMPEALECWDERL
CEEEEECCCCCCEEHHHHHHHHHHHHCCCCCHHHEEECCEEEECCCCCCHHHHHHHHHHH
IKALLPRHMQIIKQINDRFKALVDNTWPGDKQVWAKLAVVHDRQVRMANMCVVSGFAVNG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCHHHH
VAALHSDLVVKDLFPEYHQLWPNKFHNVTNGITPRRWIKQCNPQLAALLDKTLKKEWAND
HHHHHHHHHHHHHCHHHHHHCCHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
LDQLINLEKYADDATFRQQYRDIKRANKERLVKFIQARTGIEISSHAIFDIQIKRLHEYK
HHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEECCCEEEEHHHHHHHHHH
RQHLNLLHILALYKEIRENPQADRVPRVFLFGAKAAPGYYLAKNIIFAINKVAEAINNDP
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
AVGDKLKVVFLPDYCVSAAEMLIPAADISEQISTAGKEASGTGNMKLALNGALTVGTLDG
CCCCCEEEEEECHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEEECEEEEEECCC
ANVEIAEKVGEENIFIFGHTVEEVKALKAKGYDPVKWRKKDKVLDAVLKELESGQYSDGD
CCCHHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCH
KHAFDQMLHSLGKQGGDPYLVMADFAAYVEAQKQVDALYRDQEAWTRAAILNTARCGMFS
HHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SDRSIRDYQARIWQAKR
CCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SQPTFNKDQFQAALTRQWQRFGLLSASDMTPRQWWQAVSGALAELLSAQPVAQPTKGQR
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
HVNYISMEFLIGRLTGNNLLNLGWYQDVSDVLKAHDINLTDLLEEEVDPALGNGGLGRLA
HHHEEEHHHHHHHCCCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHH
ACFLDSMATVGQSATGYGLNYQYGLFRQSFVEGKQMEAPDDWHRGSYPWFRHNEALDVQV
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCEEEEEE
GIGGKVTKEGRWKPGFVITGQSWDLPVLGYRNGVAQPLRLWQATHAHPFDLTKFNDGAFL
CCCCEECCCCCCCCCEEEECCCCCCCEECCCCCCHHHHHHHHHCCCCCCCCEEECCCCEE
RAEQQGIDAEKLTKVLYPNDNHTAGKKLRLMQQYFQCACSVADILRRHHLAGRKLHELAD
EEHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCC
YEVIQLNDTHPTIAIPELLRVLLDEHQMSWDDAWAITSKTFAYTNHTLMPEALECWDERL
CEEEEECCCCCCEEHHHHHHHHHHHHCCCCCHHHEEECCEEEECCCCCCHHHHHHHHHHH
IKALLPRHMQIIKQINDRFKALVDNTWPGDKQVWAKLAVVHDRQVRMANMCVVSGFAVNG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCHHHH
VAALHSDLVVKDLFPEYHQLWPNKFHNVTNGITPRRWIKQCNPQLAALLDKTLKKEWAND
HHHHHHHHHHHHHCHHHHHHCCHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
LDQLINLEKYADDATFRQQYRDIKRANKERLVKFIQARTGIEISSHAIFDIQIKRLHEYK
HHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEECCCEEEEHHHHHHHHHH
RQHLNLLHILALYKEIRENPQADRVPRVFLFGAKAAPGYYLAKNIIFAINKVAEAINNDP
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
AVGDKLKVVFLPDYCVSAAEMLIPAADISEQISTAGKEASGTGNMKLALNGALTVGTLDG
CCCCCEEEEEECHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEEECEEEEEECCC
ANVEIAEKVGEENIFIFGHTVEEVKALKAKGYDPVKWRKKDKVLDAVLKELESGQYSDGD
CCCHHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCH
KHAFDQMLHSLGKQGGDPYLVMADFAAYVEAQKQVDALYRDQEAWTRAAILNTARCGMFS
HHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SDRSIRDYQARIWQAKR
CCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3037809; 9278503; 3155826; 2845225; 6283313; 6339728; 6986282; 9009262; 10220320; 10469642 [H]