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The map label for this gene is rbsK [H]

Identifier: 29144242

GI number: 29144242

Start: 4112739

End: 4113953

Strand: Reverse

Name: rbsK [H]

Synonym: t3974

Alternate gene names: 29144242

Gene position: 4113953-4112739 (Counterclockwise)

Preceding gene: 29144243

Following gene: 29144241

Centisome position: 85.85

GC content: 41.73

Gene sequence:

>1215_bases
ATGAAATTTGAACGCCATCATAGAATATTGAAGGAACTCAGTATTTCGGGAGTTGTAAAAGTTTCAAATCTGGCGAAAAG
TCTCAAGGTAACAAAGGAAACTATTCGTTCAGATCTCAATGAACTTGCCGGACAGGGATATCTTACTCGCTGTCATGGTG
GTGCATTTATTACCCTTGATTCTCTTGATAACGTCGCAAAAAATGAAATTGCTTATGTGCTGGAAAAATATGAATCAGCG
CAGAAAATAAAAAAAGGTCTCTCTGCCATGAAAAATAATGTATGTGTTATTGGCTCGTTCAATGTTGATATTATCAGTTA
TCTACCGAGATTACCCTCAACGGGAGAATCATTGCTGGCCGATAAATTTATTTTTTCACCCGGCGGTAAGGGATGTAATC
AGGCATTAGCAGCAAGCTATGCCGATTCTGATGTGCATTTTATTACTAAAGTCGGCTCAGATCATTTTAGCGATTACGCC
ATTAATTTTATAAACTCATCAAAAATCCATAAAAGTGTTATCTACCAGACCAAAGAAACACAAACAGGTACAGCAACCAT
CATGGTGAATGGTGATACCGGAGATAATGTCATCGCTATCTACCCTGGCGCCAACATGACAATTTCCCCTGATGAAATCA
CCATTCAAAAAGAAGCCATTGTTCATTCAGATATTGTTCTTGTCCAACTGGAGACGAATTACGAAGCGCTGCAGCAAACA
ATTCGTCTCGCACAAAAAAATGACATACCGGTCATCATCAATCCAGCGCCGTACAATGACATGGTTAACACCATCATTGA
TAACATTGACTATATTACGCCAAATGAAACGGAAGCCGGCCTGCTGGCCAATATGGCGGTTAATGATATCGAATCAGCCA
AATGCGCGGCCAAAATTATTCACCAGAAAGGCGTCAAAAATACCATTATTACATTAGGTAGCAAAGGTTCGCTTGCTTAT
GACGGCACACAATTCATCTATTCCCCGGCATTTCCGGCAGTTGTAAAAAATACGGCGGGAGCGGGTGACGCTTTCAATGG
CGCCCTCTCATCTGGCCTTGCAAAAGGAAAGTCACTGGCATCCGCATTGTGCTACGCCAGCGCATTTGCCTCACTTGCGG
TTGAAACGCCTAATGCCTCTGATATGCCGGAAAACGACTCCGTTCTTCATCGTATTCAGGGTTCACATTACAAACAAACT
ATCTCTACTCACTAA

Upstream 100 bases:

>100_bases
ATTACATTTTTGTTTTTTTTTGGTTTCTGCCATCACTTTATGGTGACAATCACAACAATATACTCCTCCCGGGACTAATT
TAACCACGGTGAGGTAAAAA

Downstream 100 bases:

>100_bases
ATCAAGGAGCAGACTATGAACAATACGCAGAAAAAACTAAAGGTGCTCTTTATTGGAGAATCCTGGCATATTCATATGAT
TCATTCAAAAGGTTATGACA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKFERHHRILKELSISGVVKVSNLAKSLKVTKETIRSDLNELAGQGYLTRCHGGAFITLDSLDNVAKNEIAYVLEKYESA
QKIKKGLSAMKNNVCVIGSFNVDIISYLPRLPSTGESLLADKFIFSPGGKGCNQALAASYADSDVHFITKVGSDHFSDYA
INFINSSKIHKSVIYQTKETQTGTATIMVNGDTGDNVIAIYPGANMTISPDEITIQKEAIVHSDIVLVQLETNYEALQQT
IRLAQKNDIPVIINPAPYNDMVNTIIDNIDYITPNETEAGLLANMAVNDIESAKCAAKIIHQKGVKNTIITLGSKGSLAY
DGTQFIYSPAFPAVVKNTAGAGDAFNGALSSGLAKGKSLASALCYASAFASLAVETPNASDMPENDSVLHRIQGSHYKQT
ISTH

Sequences:

>Translated_404_residues
MKFERHHRILKELSISGVVKVSNLAKSLKVTKETIRSDLNELAGQGYLTRCHGGAFITLDSLDNVAKNEIAYVLEKYESA
QKIKKGLSAMKNNVCVIGSFNVDIISYLPRLPSTGESLLADKFIFSPGGKGCNQALAASYADSDVHFITKVGSDHFSDYA
INFINSSKIHKSVIYQTKETQTGTATIMVNGDTGDNVIAIYPGANMTISPDEITIQKEAIVHSDIVLVQLETNYEALQQT
IRLAQKNDIPVIINPAPYNDMVNTIIDNIDYITPNETEAGLLANMAVNDIESAKCAAKIIHQKGVKNTIITLGSKGSLAY
DGTQFIYSPAFPAVVKNTAGAGDAFNGALSSGLAKGKSLASALCYASAFASLAVETPNASDMPENDSVLHRIQGSHYKQT
ISTH
>Mature_404_residues
MKFERHHRILKELSISGVVKVSNLAKSLKVTKETIRSDLNELAGQGYLTRCHGGAFITLDSLDNVAKNEIAYVLEKYESA
QKIKKGLSAMKNNVCVIGSFNVDIISYLPRLPSTGESLLADKFIFSPGGKGCNQALAASYADSDVHFITKVGSDHFSDYA
INFINSSKIHKSVIYQTKETQTGTATIMVNGDTGDNVIAIYPGANMTISPDEITIQKEAIVHSDIVLVQLETNYEALQQT
IRLAQKNDIPVIINPAPYNDMVNTIIDNIDYITPNETEAGLLANMAVNDIESAKCAAKIIHQKGVKNTIITLGSKGSLAY
DGTQFIYSPAFPAVVKNTAGAGDAFNGALSSGLAKGKSLASALCYASAFASLAVETPNASDMPENDSVLHRIQGSHYKQT
ISTH

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=262, Percent_Identity=32.824427480916, Blast_Score=132, Evalue=4e-31,
Organism=Escherichia coli, GI1790193, Length=272, Percent_Identity=36.0294117647059, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI1788491, Length=308, Percent_Identity=25.974025974026, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082343, Length=299, Percent_Identity=24.7491638795987, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788017, Length=258, Percent_Identity=24.8062015503876, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=293, Percent_Identity=33.7883959044369, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319884, Length=323, Percent_Identity=28.1733746130031, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI20128807, Length=298, Percent_Identity=33.5570469798658, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24583886, Length=278, Percent_Identity=28.0575539568345, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 43483; Mature: 43483

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS51000 HTH_DEOR_2 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFERHHRILKELSISGVVKVSNLAKSLKVTKETIRSDLNELAGQGYLTRCHGGAFITLD
CCCHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEC
SLDNVAKNEIAYVLEKYESAQKIKKGLSAMKNNVCVIGSFNVDIISYLPRLPSTGESLLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCCCCCCCHHHHH
DKFIFSPGGKGCNQALAASYADSDVHFITKVGSDHFSDYAINFINSSKIHKSVIYQTKET
HHHEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEECCCHHHHHHHHEECCCC
QTGTATIMVNGDTGDNVIAIYPGANMTISPDEITIQKEAIVHSDIVLVQLETNYEALQQT
CCCEEEEEEECCCCCCEEEEECCCCCEECCCCEEEEHHHEEECCEEEEEEECCHHHHHHH
IRLAQKNDIPVIINPAPYNDMVNTIIDNIDYITPNETEAGLLANMAVNDIESAKCAAKII
HHHHHCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
HQKGVKNTIITLGSKGSLAYDGTQFIYSPAFPAVVKNTAGAGDAFNGALSSGLAKGKSLA
HHCCCCCEEEEECCCCCEEECCCEEEECCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
SALCYASAFASLAVETPNASDMPENDSVLHRIQGSHYKQTISTH
HHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure
MKFERHHRILKELSISGVVKVSNLAKSLKVTKETIRSDLNELAGQGYLTRCHGGAFITLD
CCCHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEC
SLDNVAKNEIAYVLEKYESAQKIKKGLSAMKNNVCVIGSFNVDIISYLPRLPSTGESLLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCCCCCCCHHHHH
DKFIFSPGGKGCNQALAASYADSDVHFITKVGSDHFSDYAINFINSSKIHKSVIYQTKET
HHHEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEECCCHHHHHHHHEECCCC
QTGTATIMVNGDTGDNVIAIYPGANMTISPDEITIQKEAIVHSDIVLVQLETNYEALQQT
CCCEEEEEEECCCCCCEEEEECCCCCEECCCCEEEEHHHEEECCEEEEEEECCHHHHHHH
IRLAQKNDIPVIINPAPYNDMVNTIIDNIDYITPNETEAGLLANMAVNDIESAKCAAKII
HHHHHCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
HQKGVKNTIITLGSKGSLAYDGTQFIYSPAFPAVVKNTAGAGDAFNGALSSGLAKGKSLA
HHCCCCCEEEEECCCCCEEECCCEEEECCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
SALCYASAFASLAVETPNASDMPENDSVLHRIQGSHYKQTISTH
HHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]