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The map label for this gene is ftsY [H]

Identifier: 29144220

GI number: 29144220

Start: 4090423

End: 4091898

Strand: Direct

Name: ftsY [H]

Synonym: t3951

Alternate gene names: 29144220

Gene position: 4090423-4091898 (Clockwise)

Preceding gene: 29144217

Following gene: 29144221

Centisome position: 85.36

GC content: 55.08

Gene sequence:

>1476_bases
ATGGCAAAACAGAAAAAACGTGGCTTCTTTTCCTGGTTGGGCTTCGGTGATAAAGAGCAGAAGCAGGAACAGACCGAAGA
ACAGCAGATTGTTGAGGAACAACGACCGGTTGAGCCCCCTGTTGAAACGGCGGCAGACGTAGACGCGCAAACGCCCGCGC
ACAGCAAAGCAGAAACAGAAGCCTTTGCGGAAGAGGTGGTGGACGTTACTGAGAAAGTTCAGGAGAGCGAAAAACCGCAG
CCGGTAGAGCCGGAGCCCACGGCGGCCATTGAGATGGCAGCGCCGCAGATCGCGGTGGAACGCGAGGAATTGCCGCTGCC
GGAAGAGGTCAAAGACGAGGCTATCTCGCCGGAAGAGTGGCAGGCCGAAGCGGAAACCGTAGAGGTCATTGCCGCGGTAG
AAGAAGAGGGCGAAAACGCGGCGAAATTCACCGACGAAGAGCTGGAAGCGCAGGCGCTGGCCGCTCAGGCGGCGGAAGAG
GCGGTGATGGTTGTTCCGCCGGCGGAAGAAGACGCGCCGGTGGAAGCGATCGTTCAGGAGCAGGAAAAACCGACTAAAGA
AGGTTTCTTTGCCCGCCTGAAACGCAGTCTGCTGAAAACCAAAGAAAATCTCGGTTCCGGATTTATCAGTCTGTTCCGCG
GCAAGAAAATCGACGATGATTTGTTCGAGGAGCTGGAAGAGCAGTTGCTCATCGCTGATGTCGGGGTGGAAACCACGCGT
AAGATTATCGCTAATCTGACGGAAGGCGCCAGCCGCAAACAGCTTAAAGATGCCGAGGCGCTGTATGGTCTGTTGAAAGA
CGAGATGGGCGAGATTCTGGCGAAGGTAGACGAACCGCTTAATATTGAAGGTAAAACGCCTTTTGTTATTCTGATGGTTG
GCGTGAACGGCGTGGGTAAAACCACCACTATCGGTAAACTGGCGCGCCAGTTTGAGCAGCAGGGTAAATCAGTGATGCTG
GCGGCGGGGGATACTTTCCGCGCGGCGGCGGTCGAACAGCTACAGGTCTGGGGACAGCGTAACAACATTCCGGTTATCGC
CCAGCATACCGGCGCGGACTCCGCCTCGGTGATTTTTGACGCTATCCAGGCCGCGAAGGCGCGTAATGTGGATGTGTTAA
TTGCCGATACGGCAGGGCGTTTGCAGAACAAGTCGCACCTGATGGAAGAGCTGAAAAAAATCGTTCGCGTCATGAAAAAG
CTGGACGAAGAAGCGCCACATGAAGTTATGCTGACCATTGACGCCAGCACCGGACAGAACGCGGTAAGCCAGGCCAAACT
GTTCCATGAAGCGGTGGGCTTAACCGGTATTACCCTGACCAAGCTGGACGGTACGGCGAAAGGCGGGGTGATTTTCTCGG
TAGCTGACCAGTTTGGCATTCCTATCCGTTACATTGGCGTGGGCGAACGTATCGAGGATTTGCGTCCGTTTAAGGCGGAC
GATTTTATTGAGGCACTTTTTGCCCGAGAGGATTAA

Upstream 100 bases:

>100_bases
AAGTTATTCCAGGCGGTGATGTGAATTAAGTTAAGTGATAGACTATTTCATCATTTTTTTAGCTTCCATGTATATAGCGC
CGCGAGGGGTGTAGTCGCAG

Downstream 100 bases:

>100_bases
CAATGATTCGCTTTGAACATGTCAGCAAGGCCTATCTCGGCGGGAGACAAGCGCTGCAGGGAGTGACATTCCATATGCGG
CCAGGCGAGATGGCGTTTCT

Product: cell division protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MAKQKKRGFFSWLGFGDKEQKQEQTEEQQIVEEQRPVEPPVETAADVDAQTPAHSKAETEAFAEEVVDVTEKVQESEKPQ
PVEPEPTAAIEMAAPQIAVEREELPLPEEVKDEAISPEEWQAEAETVEVIAAVEEEGENAAKFTDEELEAQALAAQAAEE
AVMVVPPAEEDAPVEAIVQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLFRGKKIDDDLFEELEEQLLIADVGVETTR
KIIANLTEGASRKQLKDAEALYGLLKDEMGEILAKVDEPLNIEGKTPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVML
AAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNVDVLIADTAGRLQNKSHLMEELKKIVRVMKK
LDEEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKAD
DFIEALFARED

Sequences:

>Translated_491_residues
MAKQKKRGFFSWLGFGDKEQKQEQTEEQQIVEEQRPVEPPVETAADVDAQTPAHSKAETEAFAEEVVDVTEKVQESEKPQ
PVEPEPTAAIEMAAPQIAVEREELPLPEEVKDEAISPEEWQAEAETVEVIAAVEEEGENAAKFTDEELEAQALAAQAAEE
AVMVVPPAEEDAPVEAIVQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLFRGKKIDDDLFEELEEQLLIADVGVETTR
KIIANLTEGASRKQLKDAEALYGLLKDEMGEILAKVDEPLNIEGKTPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVML
AAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNVDVLIADTAGRLQNKSHLMEELKKIVRVMKK
LDEEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKAD
DFIEALFARED
>Mature_490_residues
AKQKKRGFFSWLGFGDKEQKQEQTEEQQIVEEQRPVEPPVETAADVDAQTPAHSKAETEAFAEEVVDVTEKVQESEKPQP
VEPEPTAAIEMAAPQIAVEREELPLPEEVKDEAISPEEWQAEAETVEVIAAVEEEGENAAKFTDEELEAQALAAQAAEEA
VMVVPPAEEDAPVEAIVQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLFRGKKIDDDLFEELEEQLLIADVGVETTRK
IIANLTEGASRKQLKDAEALYGLLKDEMGEILAKVDEPLNIEGKTPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLA
AGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNVDVLIADTAGRLQNKSHLMEELKKIVRVMKKL
DEEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADD
FIEALFARED

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=276, Percent_Identity=30.7971014492754, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI226371618, Length=203, Percent_Identity=35.9605911330049, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI295424842, Length=225, Percent_Identity=33.3333333333333, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI23308697, Length=225, Percent_Identity=33.3333333333333, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI89061728, Length=147, Percent_Identity=32.6530612244898, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1789874, Length=501, Percent_Identity=82.435129740519, Blast_Score=728, Evalue=0.0,
Organism=Escherichia coli, GI1788963, Length=311, Percent_Identity=32.7974276527331, Blast_Score=160, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI193206261, Length=318, Percent_Identity=30.8176100628931, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17539958, Length=282, Percent_Identity=28.3687943262411, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6325345, Length=203, Percent_Identity=37.9310344827586, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6320498, Length=225, Percent_Identity=33.7777777777778, Blast_Score=104, Evalue=4e-23,
Organism=Drosophila melanogaster, GI17647949, Length=283, Percent_Identity=31.4487632508834, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24641198, Length=333, Percent_Identity=27.6276276276276, Blast_Score=116, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 53791; Mature: 53660

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQKKRGFFSWLGFGDKEQKQEQTEEQQIVEEQRPVEPPVETAADVDAQTPAHSKAETE
CCCCHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCHHHHH
AFAEEVVDVTEKVQESEKPQPVEPEPTAAIEMAAPQIAVEREELPLPEEVKDEAISPEEW
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCHHEECHHCCCCCHHHHHCCCCCHHH
QAEAETVEVIAAVEEEGENAAKFTDEELEAQALAAQAAEEAVMVVPPAEEDAPVEAIVQE
HHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHH
QEKPTKEGFFARLKRSLLKTKENLGSGFISLFRGKKIDDDLFEELEEQLLIADVGVETTR
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHH
KIIANLTEGASRKQLKDAEALYGLLKDEMGEILAKVDEPLNIEGKTPFVILMVGVNGVGK
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCC
TTTIGKLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFD
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHH
AIQAAKARNVDVLIADTAGRLQNKSHLMEELKKIVRVMKKLDEEAPHEVMLTIDASTGQN
HHHHHHCCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCH
AVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKAD
HHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEHHHHCCCEEEECCCHHHHHCCCCCHH
DFIEALFARED
HHHHHHHHCCC
>Mature Secondary Structure 
AKQKKRGFFSWLGFGDKEQKQEQTEEQQIVEEQRPVEPPVETAADVDAQTPAHSKAETE
CCCHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCHHHHH
AFAEEVVDVTEKVQESEKPQPVEPEPTAAIEMAAPQIAVEREELPLPEEVKDEAISPEEW
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCHHEECHHCCCCCHHHHHCCCCCHHH
QAEAETVEVIAAVEEEGENAAKFTDEELEAQALAAQAAEEAVMVVPPAEEDAPVEAIVQE
HHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHH
QEKPTKEGFFARLKRSLLKTKENLGSGFISLFRGKKIDDDLFEELEEQLLIADVGVETTR
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHH
KIIANLTEGASRKQLKDAEALYGLLKDEMGEILAKVDEPLNIEGKTPFVILMVGVNGVGK
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCC
TTTIGKLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFD
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHH
AIQAAKARNVDVLIADTAGRLQNKSHLMEELKKIVRVMKKLDEEAPHEVMLTIDASTGQN
HHHHHHCCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCH
AVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKAD
HHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEHHHHCCCEEEECCCHHHHHCCCCCHH
DFIEALFARED
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]