Click here to switch to the map view.

The map label for this gene is tcp [H]

Identifier: 29144214

GI number: 29144214

Start: 4084162

End: 4085805

Strand: Reverse

Name: tcp [H]

Synonym: t3945

Alternate gene names: 29144214

Gene position: 4085805-4084162 (Counterclockwise)

Preceding gene: 29144215

Following gene: 29144212

Centisome position: 85.26

GC content: 55.54

Gene sequence:

>1644_bases
ATGAAAAATATCAAAGTCATCACCGGCGTTATCGCGACGCTGGGCATATTTAGCGCCTTATTGTTGGTGACAGGAATACT
GTTTTATTCCGCCGTCAGCAGCGATCGGCTGAATTTCCAGAATGCGAGCGCACTGAGTTACCAACAACAGGAACTGGGCG
GCAGTTTTCAGACATTGATTGAAACCCGCGTCACCATTAACCGCGTGGCGATACGCATGTTAAAAAATCAGCGCGATCCC
GCCTCGCTGGACGCCATGAACACGCTGTTAACCAACGCTGGCGCGTCGCTCAACGAAGCGGAAAAGCATTTCAACAACTA
CGTGAACTCCGAAGCGATCGCAGGCAAAGATCCGGCGTTGGATGCCCAGGCCGAAGCCAGCTTTAAGCAGATGTATGACG
TTTTGCAGCAGTCTATCCACTATCTTAAAGCCGATAATTACGCCGCCTATGGCAACCTTGACGCGCAAAAAGCGCAGGAT
GACATGGAGCAGGTATATGACCAGTGGCTCTCTCAAAATGCGCAATTAATAAAATTAGCCAGCGATCAGAATCAGAGCAG
TTTTACCCAGATGCAATGGACGCTGGGGATAATTCTACTTATCGTGCTCATCGTGCTGGCGTTTATCTGGCTGGGGCTGC
AACGCGTTCTACTCCGCCCGCTGCAACGGATTATGGCGCACATTCAAACGATCGCCGACGGCGATCTTACCCATGAGATA
GAGGCTGAAGGACGTAGTGAAATGGGCCAACTGGCTGCCGGTCTCAAAACGATGCAGCAGTCGTTAATCCGTACCGTCAG
CGCGGTGCGCGATAACGCAGACTCTATCTATACTGGCGCAGGCGAAATTTCCGCTGGCAGCAGCGACCTCTCTTCCCGTA
CCGAACAGCAGGCCTCGGCGCTGGAGGAGACCGCCGCCAGCATGGAACAGTTAACCGCCACGGTACGGCAAAACACCGAT
AACGCACGACAGGCGACGGGTCTGGCGAAAACCGCATCAGAAACCGCGCGTAAAGGAGGACGCGTGGTGGATAACGTAGT
GAGCACCATGAACGATATCGCCGAAAGCTCGGAAAAAATCGTGGACATCACCAGCGTGATTGACGGTATCGCCTTCCAGA
CTAATATCCTGGCGCTGAACGCTGCGGTAGAAGCCGCCCGCGCCGGCGAACAGGGGCGAGGATTCGCGGTTGTGGCCGGA
GAGGTACGCACGTTGGCCAGCCGTAGCGCGCAGGCCGCCAAAGAGATCAAAGTGCTGATTGAAAACTCCGTGTCGCGCAT
TGATACCGGCTCTACGCAGGTACGCGAAGCGGGAGAAACCATGAAAGAGATCGTTAACGCCGTGACCCGCGTGACCGATA
TTATGGGCGAAATCGCCTCTGCCTCCGATGAGCAAAGCAAAGGCATTGAGCAGGTGGCGCAGGCGGTATCGGAAATGGAC
AGCGTGACGCAGCAAAACGCCTCGCTGGTAGAGGAATCCGCAGCAGCAGCGGCGGCGCTGGAAGATCAGGCTAACGAGCT
TCGTCAGGCGGTCGCCGCGTTCCGCATCCAGAAACAACCTCGTCGGGAGGCGTCGCCGACGCCGTTAAGCAAAGGCTTAA
CGCCACAGCCCGCCGCAGAACAGGCGAACTGGGAAAGCTTCTAA

Upstream 100 bases:

>100_bases
ATCAAACCATTAATCAGAAATAGCGCGATTTGATGTAAGGTTAATTTTTATCCAACCGATATTGATCATACCGTCTACAA
AATAAGGAATGTTAGGCACT

Downstream 100 bases:

>100_bases
TCAGAATGCTATCTGCCGTGCGGTTAATGCGCTTTACGCAATAAATAGCGGTACGGCAGACCCTCCGTCTCTTGCGCCAG
CAAATCGTGTTCCATAAAGG

Product: methyl-accepting chemotaxis citrate transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASALSYQQQELGGSFQTLIETRVTINRVAIRMLKNQRDP
ASLDAMNTLLTNAGASLNEAEKHFNNYVNSEAIAGKDPALDAQAEASFKQMYDVLQQSIHYLKADNYAAYGNLDAQKAQD
DMEQVYDQWLSQNAQLIKLASDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLLRPLQRIMAHIQTIADGDLTHEI
EAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSIYTGAGEISAGSSDLSSRTEQQASALEETAASMEQLTATVRQNTD
NARQATGLAKTASETARKGGRVVDNVVSTMNDIAESSEKIVDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLASRSAQAAKEIKVLIENSVSRIDTGSTQVREAGETMKEIVNAVTRVTDIMGEIASASDEQSKGIEQVAQAVSEMD
SVTQQNASLVEESAAAAAALEDQANELRQAVAAFRIQKQPRREASPTPLSKGLTPQPAAEQANWESF

Sequences:

>Translated_547_residues
MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASALSYQQQELGGSFQTLIETRVTINRVAIRMLKNQRDP
ASLDAMNTLLTNAGASLNEAEKHFNNYVNSEAIAGKDPALDAQAEASFKQMYDVLQQSIHYLKADNYAAYGNLDAQKAQD
DMEQVYDQWLSQNAQLIKLASDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLLRPLQRIMAHIQTIADGDLTHEI
EAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSIYTGAGEISAGSSDLSSRTEQQASALEETAASMEQLTATVRQNTD
NARQATGLAKTASETARKGGRVVDNVVSTMNDIAESSEKIVDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLASRSAQAAKEIKVLIENSVSRIDTGSTQVREAGETMKEIVNAVTRVTDIMGEIASASDEQSKGIEQVAQAVSEMD
SVTQQNASLVEESAAAAAALEDQANELRQAVAAFRIQKQPRREASPTPLSKGLTPQPAAEQANWESF
>Mature_547_residues
MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASALSYQQQELGGSFQTLIETRVTINRVAIRMLKNQRDP
ASLDAMNTLLTNAGASLNEAEKHFNNYVNSEAIAGKDPALDAQAEASFKQMYDVLQQSIHYLKADNYAAYGNLDAQKAQD
DMEQVYDQWLSQNAQLIKLASDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLLRPLQRIMAHIQTIADGDLTHEI
EAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSIYTGAGEISAGSSDLSSRTEQQASALEETAASMEQLTATVRQNTD
NARQATGLAKTASETARKGGRVVDNVVSTMNDIAESSEKIVDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLASRSAQAAKEIKVLIENSVSRIDTGSTQVREAGETMKEIVNAVTRVTDIMGEIASASDEQSKGIEQVAQAVSEMD
SVTQQNASLVEESAAAAAALEDQANELRQAVAAFRIQKQPRREASPTPLSKGLTPQPAAEQANWESF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=554, Percent_Identity=53.4296028880866, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1788195, Length=555, Percent_Identity=53.3333333333333, Blast_Score=494, Evalue=1e-141,
Organism=Escherichia coli, GI1787690, Length=460, Percent_Identity=48.9130434782609, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1788194, Length=445, Percent_Identity=50.1123595505618, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1789453, Length=329, Percent_Identity=41.9452887537994, Blast_Score=221, Evalue=8e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 58947; Mature: 58947

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50885 HAMP ; PS00538 CHEMOTAXIS_TRANSDUC_1 ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASALSYQQQELGGSFQTLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHH
ETRVTINRVAIRMLKNQRDPASLDAMNTLLTNAGASLNEAEKHFNNYVNSEAIAGKDPAL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
DAQAEASFKQMYDVLQQSIHYLKADNYAAYGNLDAQKAQDDMEQVYDQWLSQNAQLIKLA
CCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEC
SDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLLRPLQRIMAHIQTIADGDLTHEI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSIYTGAGEISAGSSDLSSRTEQQASA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHH
LEETAASMEQLTATVRQNTDNARQATGLAKTASETARKGGRVVDNVVSTMNDIAESSEKI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLASRSAQAAKEIKVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
ENSVSRIDTGSTQVREAGETMKEIVNAVTRVTDIMGEIASASDEQSKGIEQVAQAVSEMD
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SVTQQNASLVEESAAAAAALEDQANELRQAVAAFRIQKQPRREASPTPLSKGLTPQPAAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
QANWESF
CCCCCCC
>Mature Secondary Structure
MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASALSYQQQELGGSFQTLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHH
ETRVTINRVAIRMLKNQRDPASLDAMNTLLTNAGASLNEAEKHFNNYVNSEAIAGKDPAL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
DAQAEASFKQMYDVLQQSIHYLKADNYAAYGNLDAQKAQDDMEQVYDQWLSQNAQLIKLA
CCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEC
SDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLLRPLQRIMAHIQTIADGDLTHEI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSIYTGAGEISAGSSDLSSRTEQQASA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHH
LEETAASMEQLTATVRQNTDNARQATGLAKTASETARKGGRVVDNVVSTMNDIAESSEKI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLASRSAQAAKEIKVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
ENSVSRIDTGSTQVREAGETMKEIVNAVTRVTDIMGEIASASDEQSKGIEQVAQAVSEMD
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SVTQQNASLVEESAAAAAALEDQANELRQAVAAFRIQKQPRREASPTPLSKGLTPQPAAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
QANWESF
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]