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The map label for this gene is idnR [H]

Identifier: 29144102

GI number: 29144102

Start: 3943448

End: 3944503

Strand: Direct

Name: idnR [H]

Synonym: t3823

Alternate gene names: 29144102

Gene position: 3943448-3944503 (Clockwise)

Preceding gene: 29144100

Following gene: 29144110

Centisome position: 82.29

GC content: 54.64

Gene sequence:

>1056_bases
ATGATGAATAATGCGCGGATAAATCAGCCAATCTTTGCAGGGGCATCAGACGTGAAGAGAACCAAATCACCTCGTGCGCC
GACGCTGGAAGATGTAGCACGTAGCGCCGGGCTGTCTCCGATGACAGTCAGCCGGGCATTGAATTCGCCACAACTGGTTC
GCCCCAAAACGGTTGAGAAAGTCATGCAGGCGGTTCGCGTCACAGGCTACATACCCAACGCGTTAGCCGGTGGTCTGGCG
TCGCGACGGAGTAAATTAATCGCTGTCGTCGTGCCGCAAATTAACAACAACATGTTTGTCGATACCATCCAGTCACTGAG
CGATGAACTGGCCCGACGCGGATATCACATATTGCTGTGCGTGGCGGGATATACCGAACAAACGGAAGCGGAGTTGGTGG
CGACACTGCTTTCCCGCCGCCCCGATGGCGTGGTGCTTACCGGGATCCATCACACGATAGAACTGAAAAAGGTCATCCTG
AACGCGGCTATTCCGGTGGTGGAAATTTGGGACTTAACGCCCACGCCGCTTGATATGCTGGTCGGTTTTTCCCATGAAAA
AGTCGGGCAGGCGACGGGGGAGTATCTTCTGAGTAAGGGCTATCGTCGTCCCGGCTTGTTGTGGACCGCCGATCGCCGAG
CCGCGCAACGTAAGCAGGGGTTATGTAGTGTTCTTCAACGCCACGCTATTCATGCCGTACCGCAGGTGGATGTCCCCCTT
CCGGCATCGCTTTCGCTGGGGCGTAGCGGTTTAAGCCAGCTTTTTGACGAAGGGACGTTTGATGTCATTGTTTGCAGTTC
TGATACCCTGGCACAGGGGGCGATGATGGAGGCGGAAAGCCGTGGTTTGCGCATCCCGCATGATTTAGCGGTTATTGGTT
TTGGCGACCTTGATTTTGCCGCCAGCAATCGACCGTCAATTACTACCGTAAGCGTTGACAGACGCGCCATTGGTCAGCGC
GCCGCTACGCTGTTGGCCGATCGTATTGAACAGAAACCGTGCGCAGAAGCTATTGTGGATATTGGCTTTCATTTGATTGA
GCGAGAGTCCGCATAA

Upstream 100 bases:

>100_bases
ATAATACAAAATGATGTCGCTATCATTTTGTAATGACTGAGCTTGATAAGCTACTGTATTTACGGCCTTTCCTGATGCGA
AGCTGGCAATAGCCGCAGGC

Downstream 100 bases:

>100_bases
ACGGGAACATGCCATCGGGATCGGCCAGGCCGGATCAGGCGTTAGCCGCCATCCGGCATTGAATATATTACGACCGCAAT
ACCGCGCCGGGGTATCCTAA

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: L-idonate regulatory protein [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MMNNARINQPIFAGASDVKRTKSPRAPTLEDVARSAGLSPMTVSRALNSPQLVRPKTVEKVMQAVRVTGYIPNALAGGLA
SRRSKLIAVVVPQINNNMFVDTIQSLSDELARRGYHILLCVAGYTEQTEAELVATLLSRRPDGVVLTGIHHTIELKKVIL
NAAIPVVEIWDLTPTPLDMLVGFSHEKVGQATGEYLLSKGYRRPGLLWTADRRAAQRKQGLCSVLQRHAIHAVPQVDVPL
PASLSLGRSGLSQLFDEGTFDVIVCSSDTLAQGAMMEAESRGLRIPHDLAVIGFGDLDFAASNRPSITTVSVDRRAIGQR
AATLLADRIEQKPCAEAIVDIGFHLIERESA

Sequences:

>Translated_351_residues
MMNNARINQPIFAGASDVKRTKSPRAPTLEDVARSAGLSPMTVSRALNSPQLVRPKTVEKVMQAVRVTGYIPNALAGGLA
SRRSKLIAVVVPQINNNMFVDTIQSLSDELARRGYHILLCVAGYTEQTEAELVATLLSRRPDGVVLTGIHHTIELKKVIL
NAAIPVVEIWDLTPTPLDMLVGFSHEKVGQATGEYLLSKGYRRPGLLWTADRRAAQRKQGLCSVLQRHAIHAVPQVDVPL
PASLSLGRSGLSQLFDEGTFDVIVCSSDTLAQGAMMEAESRGLRIPHDLAVIGFGDLDFAASNRPSITTVSVDRRAIGQR
AATLLADRIEQKPCAEAIVDIGFHLIERESA
>Mature_351_residues
MMNNARINQPIFAGASDVKRTKSPRAPTLEDVARSAGLSPMTVSRALNSPQLVRPKTVEKVMQAVRVTGYIPNALAGGLA
SRRSKLIAVVVPQINNNMFVDTIQSLSDELARRGYHILLCVAGYTEQTEAELVATLLSRRPDGVVLTGIHHTIELKKVIL
NAAIPVVEIWDLTPTPLDMLVGFSHEKVGQATGEYLLSKGYRRPGLLWTADRRAAQRKQGLCSVLQRHAIHAVPQVDVPL
PASLSLGRSGLSQLFDEGTFDVIVCSSDTLAQGAMMEAESRGLRIPHDLAVIGFGDLDFAASNRPSITTVSVDRRAIGQR
AATLLADRIEQKPCAEAIVDIGFHLIERESA

Specific function: Idn operon regulator. May repress gntKU and gntT genes when growing on L-idonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790715, Length=323, Percent_Identity=30.3405572755418, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI48994940, Length=324, Percent_Identity=30.8641975308642, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790369, Length=325, Percent_Identity=28.9230769230769, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1787948, Length=329, Percent_Identity=24.6200607902736, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790194, Length=329, Percent_Identity=25.531914893617, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786540, Length=324, Percent_Identity=28.0864197530864, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788474, Length=295, Percent_Identity=29.4915254237288, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789068, Length=291, Percent_Identity=24.3986254295533, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789202, Length=289, Percent_Identity=25.2595155709343, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786268, Length=295, Percent_Identity=28.4745762711864, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787906, Length=326, Percent_Identity=23.9263803680982, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38033; Mature: 38033

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNNARINQPIFAGASDVKRTKSPRAPTLEDVARSAGLSPMTVSRALNSPQLVRPKTVEK
CCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHH
VMQAVRVTGYIPNALAGGLASRRSKLIAVVVPQINNNMFVDTIQSLSDELARRGYHILLC
HHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEE
VAGYTEQTEAELVATLLSRRPDGVVLTGIHHTIELKKVILNAAIPVVEIWDLTPTPLDML
EECCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHH
VGFSHEKVGQATGEYLLSKGYRRPGLLWTADRRAAQRKQGLCSVLQRHAIHAVPQVDVPL
HCCCHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PASLSLGRSGLSQLFDEGTFDVIVCSSDTLAQGAMMEAESRGLRIPHDLAVIGFGDLDFA
CCCHHHCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCC
ASNRPSITTVSVDRRAIGQRAATLLADRIEQKPCAEAIVDIGFHLIERESA
CCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMNNARINQPIFAGASDVKRTKSPRAPTLEDVARSAGLSPMTVSRALNSPQLVRPKTVEK
CCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHH
VMQAVRVTGYIPNALAGGLASRRSKLIAVVVPQINNNMFVDTIQSLSDELARRGYHILLC
HHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEE
VAGYTEQTEAELVATLLSRRPDGVVLTGIHHTIELKKVILNAAIPVVEIWDLTPTPLDML
EECCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHH
VGFSHEKVGQATGEYLLSKGYRRPGLLWTADRRAAQRKQGLCSVLQRHAIHAVPQVDVPL
HCCCHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PASLSLGRSGLSQLFDEGTFDVIVCSSDTLAQGAMMEAESRGLRIPHDLAVIGFGDLDFA
CCCHHHCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCC
ASNRPSITTVSVDRRAIGQRAATLLADRIEQKPCAEAIVDIGFHLIERESA
CCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]