Click here to switch to the map view.

The map label for this gene is rbsK [H]

Identifier: 29144016

GI number: 29144016

Start: 3839696

End: 3840616

Strand: Direct

Name: rbsK [H]

Synonym: t3725

Alternate gene names: 29144016

Gene position: 3839696-3840616 (Clockwise)

Preceding gene: 29144014

Following gene: 29144017

Centisome position: 80.13

GC content: 48.97

Gene sequence:

>921_bases
ATGGATATCGCGGTTATTGGCTCTAACATGGTGGACCTTATCACCTACACCAACCAGATGCCCAAAGAAGGGGAAACTCT
GGAAGCGCCGGCGTTTAAAATCGGCTGCGGCGGAAAAGGGGCGAACCAGGCCGTGGCGGCCGCTAAGCTCAATTCAAAAG
TATTGATGTTGACCAAAGTGGGCGACGATATTTTTGCCGACAACACCATTCGTAATCTCGAATCCTGGGGGATCAATACG
ACGTATGTAGAAAAAGTACCGTGTACCAGCAGCGGCGTAGCGCCGATTTTCGTCAACGCCAACTCCAGCAACAGCATTCT
GATCATCAAAGGCGCTAACAAGTTTCTCTCGCCGGAAGATATCGATCGCGCGGCGGAAGATTTAAAAAAATGCCAGCTTA
TTGTTCTGCAACTGGAAGTTCAGCTTGAAACGGTTTATCACGCAATAGAATTTGGCAAGAAACACGGGATTGAAGTGTTA
TTAAACCCTGCGCCAGCATTACGGGAATTAGATATGTCTTATGCCTGTAAATGCGATTTCTTTGTACCTAATGAAACCGA
GCTGGAAATATTAACCGGTATGCCAGTGGATACCTATGACCATATTCGCGCAGCGGCACGTTCGCTGGTAGATAAAGGGC
TGAACAATATTATTGTCACCATGGGCGAGAAAGGCGCGCTGTGGATGACGCGTGACCAGGAAGTCCATGTTCCGGCGTTT
AGAGTGAACGCTGTTGATACCAGCGGCGCGGGCGATGCCTTTATCGGCTGTTTCGCGCATTACTACGTCCAGAGCGGGGA
TGTGGAAGCCGCCATGAAAAAAGCCGTCCTCTTTGCCGCTTTCAGCGTCACCGGGAAAGGCACCCAATCCTCTTATCCAA
GCATTGAGCAATTTAATGAGTATCTTTCGTTGAACGAATAA

Upstream 100 bases:

>100_bases
TGATCCTCTAATCGCGATCATAGTCACAAATGATACGGAAGTAACATGATAATGTTATTTTAATATCATTGTCGTGTGAC
GATTTCTGAGAGGGAGTAAA

Downstream 100 bases:

>100_bases
CAATCACCCTGCACTGTTAAAGGTAGCACTATGAACGATAAAAACATCGTTCAGATGCCCGACGGGTATCTGAATAAGAC
ACCTCTGTTCCAGTTTATTT

Product: carbohydrate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MDIAVIGSNMVDLITYTNQMPKEGETLEAPAFKIGCGGKGANQAVAAAKLNSKVLMLTKVGDDIFADNTIRNLESWGINT
TYVEKVPCTSSGVAPIFVNANSSNSILIIKGANKFLSPEDIDRAAEDLKKCQLIVLQLEVQLETVYHAIEFGKKHGIEVL
LNPAPALRELDMSYACKCDFFVPNETELEILTGMPVDTYDHIRAAARSLVDKGLNNIIVTMGEKGALWMTRDQEVHVPAF
RVNAVDTSGAGDAFIGCFAHYYVQSGDVEAAMKKAVLFAAFSVTGKGTQSSYPSIEQFNEYLSLNE

Sequences:

>Translated_306_residues
MDIAVIGSNMVDLITYTNQMPKEGETLEAPAFKIGCGGKGANQAVAAAKLNSKVLMLTKVGDDIFADNTIRNLESWGINT
TYVEKVPCTSSGVAPIFVNANSSNSILIIKGANKFLSPEDIDRAAEDLKKCQLIVLQLEVQLETVYHAIEFGKKHGIEVL
LNPAPALRELDMSYACKCDFFVPNETELEILTGMPVDTYDHIRAAARSLVDKGLNNIIVTMGEKGALWMTRDQEVHVPAF
RVNAVDTSGAGDAFIGCFAHYYVQSGDVEAAMKKAVLFAAFSVTGKGTQSSYPSIEQFNEYLSLNE
>Mature_306_residues
MDIAVIGSNMVDLITYTNQMPKEGETLEAPAFKIGCGGKGANQAVAAAKLNSKVLMLTKVGDDIFADNTIRNLESWGINT
TYVEKVPCTSSGVAPIFVNANSSNSILIIKGANKFLSPEDIDRAAEDLKKCQLIVLQLEVQLETVYHAIEFGKKHGIEVL
LNPAPALRELDMSYACKCDFFVPNETELEILTGMPVDTYDHIRAAARSLVDKGLNNIIVTMGEKGALWMTRDQEVHVPAF
RVNAVDTSGAGDAFIGCFAHYYVQSGDVEAAMKKAVLFAAFSVTGKGTQSSYPSIEQFNEYLSLNE

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=291, Percent_Identity=39.8625429553265, Blast_Score=211, Evalue=5e-55,
Organism=Escherichia coli, GI1790193, Length=301, Percent_Identity=36.5448504983389, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI87082343, Length=305, Percent_Identity=28.5245901639344, Blast_Score=99, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17532905, Length=306, Percent_Identity=37.2549019607843, Blast_Score=201, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6319884, Length=325, Percent_Identity=28.6153846153846, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI20128807, Length=301, Percent_Identity=36.2126245847176, Blast_Score=178, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24583886, Length=303, Percent_Identity=33.3333333333333, Blast_Score=157, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33229; Mature: 33229

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIAVIGSNMVDLITYTNQMPKEGETLEAPAFKIGCGGKGANQAVAAAKLNSKVLMLTKV
CEEEEECCCCEEEHHHCCCCCCCCCEECCCEEEEECCCCCCCHHEEEEECCCCEEEEEEC
GDDIFADNTIRNLESWGINTTYVEKVPCTSSGVAPIFVNANSSNSILIIKGANKFLSPED
CCCHHCCCHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCEEEEECCCCCCCHHH
IDRAAEDLKKCQLIVLQLEVQLETVYHAIEFGKKHGIEVLLNPAPALRELDMSYACKCDF
HHHHHHHHHHHEEEEEEEEHHHHHHHHHHHHHHCCCCEEEECCCCHHHHCCCCCEEEEEE
FVPNETELEILTGMPVDTYDHIRAAARSLVDKGLNNIIVTMGEKGALWMTRDQEVHVPAF
ECCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCEEECCEE
RVNAVDTSGAGDAFIGCFAHYYVQSGDVEAAMKKAVLFAAFSVTGKGTQSSYPSIEQFNE
EEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHH
YLSLNE
HHCCCC
>Mature Secondary Structure
MDIAVIGSNMVDLITYTNQMPKEGETLEAPAFKIGCGGKGANQAVAAAKLNSKVLMLTKV
CEEEEECCCCEEEHHHCCCCCCCCCEECCCEEEEECCCCCCCHHEEEEECCCCEEEEEEC
GDDIFADNTIRNLESWGINTTYVEKVPCTSSGVAPIFVNANSSNSILIIKGANKFLSPED
CCCHHCCCHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCEEEEECCCCCCCHHH
IDRAAEDLKKCQLIVLQLEVQLETVYHAIEFGKKHGIEVLLNPAPALRELDMSYACKCDF
HHHHHHHHHHHEEEEEEEEHHHHHHHHHHHHHHCCCCEEEECCCCHHHHCCCCCEEEEEE
FVPNETELEILTGMPVDTYDHIRAAARSLVDKGLNNIIVTMGEKGALWMTRDQEVHVPAF
ECCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCEEECCEE
RVNAVDTSGAGDAFIGCFAHYYVQSGDVEAAMKKAVLFAAFSVTGKGTQSSYPSIEQFNE
EEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHH
YLSLNE
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]