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The map label for this gene is atpA [H]

Identifier: 29143947

GI number: 29143947

Start: 3756737

End: 3758278

Strand: Direct

Name: atpA [H]

Synonym: t3652

Alternate gene names: 29143947

Gene position: 3756737-3758278 (Clockwise)

Preceding gene: 29143946

Following gene: 29143948

Centisome position: 78.4

GC content: 54.99

Gene sequence:

>1542_bases
ATGCAACTGAATTCCACCGAAATCAGCGAACTGATCAAGCAGCGCATTGCTCAGTTCAATGTGGTGAGCGAAGCTCACAA
CGAAGGTACTATTGTTTCTGTTAGTGACGGTGTTATCCGCATTCACGGCTTGGCCGATTGTATGCAGGGTGAAATGATCT
CCCTGCCGGGTAACCGTTACGCTATCGCACTGAACCTGGAGCGCGACTCCGTGGGTGCGGTAGTCATGGGTCCATACGCT
GACCTTGCCGAAGGCATGAAGGTTAAATGTACGGGTCGTATCCTGGAAGTTCCGGTTGGCCGCGGTCTGCTGGGACGTGT
GGTAAACACCCTGGGTGCGCCAATCGACGGTAAAGGTCCGGTTGATAATGACGGCTTCTCTGCCGTTGAAGCGATTGCGC
CGGGCGTTATCGATCGTCAGTCTGTCGATCAGCCGGTGCAGACCGGCTATAAAGCCGTTGACTCCATGATCCCAATCGGT
CGTGGTCAGCGTGAACTGATCATCGGTGACCGTCAGACCGGTAAAACCGCGCTGGCTATCGACGCCATCATCAACCAGCG
CGACTCCGGCATCAAATGTATCTATGTCGCTATCGGCCAGAAAGCGTCCACCATCTCTAACGTGGTGCGTAAACTGGAAG
AGCACGGCGCGCTGGCTAACACCATTGTTGTGGTGGCGACCGCGTCCGAATCCGCTGCGCTGCAATATTTGGCGCCGTAT
GCCGGTTGCGCAATGGGCGAATACTTCCGTGACCGCGGTGAAGATGCGCTGATCATTTACGATGACCTGTCTAAACAGGC
TGTTGCTTACCGTCAGATCTCCCTGCTGCTCCGTCGTCCGCCAGGACGTGAAGCATTCCCGGGCGACGTATTCTACCTCC
ACTCTCGTCTGCTGGAGCGTGCTGCGCGTGTTAACGCCGACTACGTCGAAGCCTTCACTAAAGGTGAAGTGAAAGGGAAA
ACCGGTTCACTGACTGCGCTGCCGATTATCGAAACGCAGGCAGGTGACGTTTCCGCGTTCGTTCCGACCAACGTAATTTC
CATTACCGATGGTCAGATCTTCCTGGAATCTAACCTGTTTAACGCCGGTATTCGTCCTGCGGTTAACCCGGGTATCTCGG
TATCCCGTGTAGGTGGCGCAGCCCAGACCAAGATCATGAAAAAACTGTCCGGAGGTATTCGTACCGCGCTGGCGCAGTAT
CGTGAACTGGCGGCGTTCTCTCAGTTTGCATCCGACCTTGACGATGCCACCCGTAAACAGCTTGACCACGGTCAGAAAGT
GACCGAACTGCTGAAACAGAAACAGTATGCGCCGATGTCCGTCGCGCAGCAGTCTCTGGTTCTGTTCGCAGCAGAACGTG
GTTATCTGGCGGATGTCGAACTGGCGAAAATCGGTAGCTTCGAAGCCGCACTGCTGGCTTACGTCGACCGTGATCACGCT
CCGCTGATGCAAGAGATCAACCAGTCCGGTGGCTATAACGACGAAATCGAAGGCAAGCTGAAAGGCATCCTCGATTCCTT
CAAAGCAACCCAGTCCTGGTAA

Upstream 100 bases:

>100_bases
AGGCGTTATCATCCGGGCGGGTGATATGGTCATTGATGGCAGCGTACGCGGCCGTCTTGAGCGCCTTGCAGACGTCTTGC
AGTCTTAAGGGGACTGGAGC

Downstream 100 bases:

>100_bases
CGTCTGGCGGCTTGCCTTAGGGCAGGCCGTAAGGCATTGAGGAGAAGCTCATGGCCGGCGCAAAAGAGATACGTAGTAAG
ATCGCAAGCGTCCAGAACAC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYA
DLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPVDNDGFSAVEAIAPGVIDRQSVDQPVQTGYKAVDSMIPIG
RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPY
AGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNADYVEAFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQY
RELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELAKIGSFEAALLAYVDRDHA
PLMQEINQSGGYNDEIEGKLKGILDSFKATQSW

Sequences:

>Translated_513_residues
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYA
DLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPVDNDGFSAVEAIAPGVIDRQSVDQPVQTGYKAVDSMIPIG
RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPY
AGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNADYVEAFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQY
RELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELAKIGSFEAALLAYVDRDHA
PLMQEINQSGGYNDEIEGKLKGILDSFKATQSW
>Mature_513_residues
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYA
DLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPVDNDGFSAVEAIAPGVIDRQSVDQPVQTGYKAVDSMIPIG
RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPY
AGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNADYVEAFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQY
RELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELAKIGSFEAALLAYVDRDHA
PLMQEINQSGGYNDEIEGKLKGILDSFKATQSW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=513, Percent_Identity=56.140350877193, Blast_Score=557, Evalue=1e-159,
Organism=Homo sapiens, GI4757810, Length=513, Percent_Identity=56.140350877193, Blast_Score=557, Evalue=1e-159,
Organism=Homo sapiens, GI19913428, Length=314, Percent_Identity=28.9808917197452, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI19913426, Length=323, Percent_Identity=28.1733746130031, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI32189394, Length=435, Percent_Identity=24.1379310344828, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI19913424, Length=255, Percent_Identity=27.4509803921569, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=98.635477582846, Blast_Score=1033, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=340, Percent_Identity=25.8823529411765, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1788251, Length=345, Percent_Identity=24.9275362318841, Blast_Score=100, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=515, Percent_Identity=54.9514563106796, Blast_Score=553, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71988080, Length=515, Percent_Identity=54.9514563106796, Blast_Score=552, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI71988074, Length=515, Percent_Identity=51.2621359223301, Blast_Score=506, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17510931, Length=368, Percent_Identity=26.0869565217391, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=313, Percent_Identity=27.7955271565495, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=448, Percent_Identity=24.3303571428571, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17509265, Length=47, Percent_Identity=68.0851063829787, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=254, Percent_Identity=26.7716535433071, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=513, Percent_Identity=53.0214424951267, Blast_Score=553, Evalue=1e-158,
Organism=Saccharomyces cerevisiae, GI6319603, Length=370, Percent_Identity=25.9459459459459, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6322581, Length=435, Percent_Identity=25.0574712643678, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24658560, Length=514, Percent_Identity=54.863813229572, Blast_Score=548, Evalue=1e-156,
Organism=Drosophila melanogaster, GI281361666, Length=313, Percent_Identity=27.7955271565495, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24646341, Length=313, Percent_Identity=27.7955271565495, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI17136796, Length=313, Percent_Identity=27.7955271565495, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24638766, Length=435, Percent_Identity=25.9770114942529, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28574560, Length=321, Percent_Identity=25.8566978193146, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24583988, Length=255, Percent_Identity=27.843137254902, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583986, Length=255, Percent_Identity=27.843137254902, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583984, Length=255, Percent_Identity=27.843137254902, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583992, Length=255, Percent_Identity=27.843137254902, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129479, Length=245, Percent_Identity=27.7551020408163, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55114; Mature: 55114

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEHHHHHCCCEEECCCCEE
AIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGP
EEEEEECCCCCCEEEECCCHHHHCCCEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCCC
VDNDGFSAVEAIAPGVIDRQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAI
CCCCCHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHEEH
DAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPY
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHH
AGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLER
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNADYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLF
HHHCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCC
NAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQ
CCCCCCCCCCCCEEHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELAKIGSFEAALLAYVDRDHA
HHCCHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCEECCHHHHCCCHHHHHHHHHCCCCC
PLMQEINQSGGYNDEIEGKLKGILDSFKATQSW
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEHHHHHCCCEEECCCCEE
AIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGP
EEEEEECCCCCCEEEECCCHHHHCCCEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCCC
VDNDGFSAVEAIAPGVIDRQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAI
CCCCCHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHEEH
DAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPY
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHH
AGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLER
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNADYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLF
HHHCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCC
NAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQ
CCCCCCCCCCCCEEHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELAKIGSFEAALLAYVDRDHA
HHCCHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCEECCHHHHCCCHHHHHHHHHCCCCC
PLMQEINQSGGYNDEIEGKLKGILDSFKATQSW
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA