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The map label for this gene is rhtC [H]

Identifier: 29143664

GI number: 29143664

Start: 3440062

End: 3440682

Strand: Reverse

Name: rhtC [H]

Synonym: t3338

Alternate gene names: 29143664

Gene position: 3440682-3440062 (Counterclockwise)

Preceding gene: 161486779

Following gene: 29143662

Centisome position: 71.8

GC content: 55.07

Gene sequence:

>621_bases
ATGTTGATGCTATTTTTCACCGTGGCAATGGTGCACATCGTTGCGCTAATGAGCCCTGGCCCCGATTTTTTCTTCGTGTC
TCAAACTGCCGTCAGCCGTTCGCGTAAAGAAGCGATGATGGGCGTACTGGGCATCACCTGCGGCGTGATGGTATGGGCGG
GCGTGGCGCTGCTTGGCCTGCATCTCATCATCGAAAAAATGGCCTGGCTGCATACGATCATTATGGTAGGCGGCGGCCTG
TACCTGTGCTGGATGGGCTATCAGATGCTGCGCGGCGCGCTGAAAAAACAGGATGCGGCGGCGTCTTCTCCGCACATTGA
ACTGGCGCAGAGCGGGCGCAGTTTTCTCAAAGGGCTGCTGACCAATCTGTCGAATCCGAAAGCGATTATCTATTTTGGTT
CCGTTTTTTCACTGTTTGTCGGCGATAACGTCGGCGCTGCGGCGCGCTGGGGTATTTTCGCGTTAATTACCCTGGAAACG
CTGGCCTGGTTTACCGTAGTCGCCAGCCTGTTCGCGCTGCCGAAAATGCGCCGTGGCTATCAGCGTCTGGCGAAATGGAT
TGATGGCTTTGCCGGCGCTCTGTTTGCGGGCTTTGGTATTCACCTGATTATTTCGCGTTAA

Upstream 100 bases:

>100_bases
CATCCGCGCGCATGTCGATGGTGATGACGAAGAGTAGTCAGCCCGGCAAAAAAGTGCCAGGATGGTGACTCACTGAACTA
TTTCCCCGCGAGCCATTTTT

Downstream 100 bases:

>100_bases
TTTACCTCCGGGCCGGATAAACATCATCCGGCACGACTATCACGCGTGTCTTGCCGACGCCAGGAGCGCGCCTACCAGCA
TAAACAACGAACCAAACGCT

Product: threonine efflux system

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MLMLFFTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLGITCGVMVWAGVALLGLHLIIEKMAWLHTIIMVGGGL
YLCWMGYQMLRGALKKQDAAASSPHIELAQSGRSFLKGLLTNLSNPKAIIYFGSVFSLFVGDNVGAAARWGIFALITLET
LAWFTVVASLFALPKMRRGYQRLAKWIDGFAGALFAGFGIHLIISR

Sequences:

>Translated_206_residues
MLMLFFTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLGITCGVMVWAGVALLGLHLIIEKMAWLHTIIMVGGGL
YLCWMGYQMLRGALKKQDAAASSPHIELAQSGRSFLKGLLTNLSNPKAIIYFGSVFSLFVGDNVGAAARWGIFALITLET
LAWFTVVASLFALPKMRRGYQRLAKWIDGFAGALFAGFGIHLIISR
>Mature_206_residues
MLMLFFTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLGITCGVMVWAGVALLGLHLIIEKMAWLHTIIMVGGGL
YLCWMGYQMLRGALKKQDAAASSPHIELAQSGRSFLKGLLTNLSNPKAIIYFGSVFSLFVGDNVGAAARWGIFALITLET
LAWFTVVASLFALPKMRRGYQRLAKWIDGFAGALFAGFGIHLIISR

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=206, Percent_Identity=91.2621359223301, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1786522, Length=197, Percent_Identity=28.4263959390863, Blast_Score=94, Evalue=4e-21,
Organism=Escherichia coli, GI1788099, Length=202, Percent_Identity=30.1980198019802, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22480; Mature: 22480

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMLFFTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLGITCGVMVWAGVALLGL
CHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLIIEKMAWLHTIIMVGGGLYLCWMGYQMLRGALKKQDAAASSPHIELAQSGRSFLKGLL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
TNLSNPKAIIYFGSVFSLFVGDNVGAAARWGIFALITLETLAWFTVVASLFALPKMRRGY
HCCCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLAKWIDGFAGALFAGFGIHLIISR
HHHHHHHHHHHHHHHHHCHHEEEEEC
>Mature Secondary Structure
MLMLFFTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLGITCGVMVWAGVALLGL
CHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLIIEKMAWLHTIIMVGGGLYLCWMGYQMLRGALKKQDAAASSPHIELAQSGRSFLKGLL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
TNLSNPKAIIYFGSVFSLFVGDNVGAAARWGIFALITLETLAWFTVVASLFALPKMRRGY
HCCCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLAKWIDGFAGALFAGFGIHLIISR
HHHHHHHHHHHHHHHHHCHHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]