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The map label for this gene is tldD [H]

Identifier: 29143616

GI number: 29143616

Start: 3373442

End: 3374887

Strand: Reverse

Name: tldD [H]

Synonym: t3283

Alternate gene names: 29143616

Gene position: 3374887-3373442 (Counterclockwise)

Preceding gene: 29143617

Following gene: 29143614

Centisome position: 70.43

GC content: 57.12

Gene sequence:

>1446_bases
ATGAGTCTGAACCTGGTAAGTGAACAATTGCTAGCGGCGAATGGCCTGAACCATCAGGATCTGTTCGCTATTTTGGGCCA
ACTGGCCGAACGCCGTCTTGATTATGGCGACCTCTATTTTCAGTCGAGCTATCACGAATCCTGGGTTTTAGAAGACCGCA
TCATTAAAGATGGTTCATATAATATCGACCAGGGCGTTGGCGTTCGCGCCATTAGCGGCGAAAAAACCGGTTTTGCTTAT
GCTGACCAGATAAGCCTCCTTGCGCTGGAGCAGAGTGCGCAGGCAGCGCGAACCATTGTACGCGAGAACGGCGAAGGCAA
GGTAAAAACGCTCGCCGCCGTAGCGCATCAGCCGCTCTACACCACCCTTGATCCGCTGCAAAGTATGAGCCGCGAAGAGA
AGCTGGATATCCTCAGACGCGTTGATAAAGCGGCGCGAGAAGCCGATAAACGCGTGCAGGAAGTTAACGCCAGCCTGACC
GGCGTATATGAATTAATCCTCGTGGCGGCGACCGACGGGACGCTGGCGGCGGATGTCCGTCCACTGGTGCGTTTGTCCGT
TAGCGTGCAGGTGGAAGAAGACGGTAAACGCGAGCGCGGCGCCAGCGGCGGCGGCGGTCGCTTTGGTTATGAGTATTTTC
TTGCCGATCTTGACGGCGAGGTGCGCGCCGACGCGTGGGCGAAAGAAGCGGTACGCATGGCGCTGGTTAATCTCTCCGCG
GTCGCTGCGCCAGCGGGGACGTTACCGGTGGTTCTGGGCGCCGGGTGGCCGGGCGTATTGCTGCACGAAGCGGTCGGGCA
CGGGCTGGAAGGTGATTTCAACCGTCGTGGGACGTCTGTGTTTAGCGGTCAGATCGGTGAGCAGGTTGCCTCCGCGCTTT
GCACCGTAGTGGATGACGGCACAATGATGAACCGTCGTGGCTCCGTTGCTATCGATGATGAAGGTACGCCAGGCCAGTAC
AACGTATTGATTGAAAATGGCGTGCTGAAAGGATACATGCAGGACAAGCTGAACGCGCGCCTGATGGGCGCTGCGCCGAC
CGGTAACGGGCGTCGCGAATCTTATGCGCATCTGCCGATGCCGCGTATGACGAATACTTATATGTTGGCGGGGCAGTCAA
CGCCGCAGGAAATTATCGAATCCGTTGAGTATGGCATCTATGCGCCTAACTTTGGCGGCGGTCAGGTGGATATCACCTCC
GGCAAGTTTGTGTTCTCTACCTCGGAAGCGTATCTGATTGAAAACGGCAAAGTCACGACGCCGGTGAAGGGCGCGACGTT
GATTGGATCAGGCATTGAAACGATGCAACAGATCTCCATGGTCGGCAACGACCTTAAGCTGGATAACGGGGTGGGGGTCT
GCGGTAAAGAGGGCCAAAGCCTGCCGGTAGGCGTAGGCCAGCCGACGCTGAAAGTCGATAACCTGACGGTTGGCGGCACC
GCATAA

Upstream 100 bases:

>100_bases
GCCGGACGGCGCTGCGTTTATCCGGTTTGCACAATCTAACAACGTAGTCCGGATAAGGCGTGAACCGCCATCCGGCAGAA
ATCAACGAGTAGCAAAAACG

Downstream 100 bases:

>100_bases
CTGTCCGCCTTATCAGGCCTGTGGTATGTGCCGCCCAGGCCTGATAAGCGCAGCGCCATCAGGCAATGTCTGCCTCGGGT
GGCATCTGATCTACAATCGT

Product: protease TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSLNLVSEQLLAANGLNHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAY
ADQISLLALEQSAQAARTIVRENGEGKVKTLAAVAHQPLYTTLDPLQSMSREEKLDILRRVDKAAREADKRVQEVNASLT
GVYELILVAATDGTLAADVRPLVRLSVSVQVEEDGKRERGASGGGGRFGYEYFLADLDGEVRADAWAKEAVRMALVNLSA
VAAPAGTLPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQIGEQVASALCTVVDDGTMMNRRGSVAIDDEGTPGQY
NVLIENGVLKGYMQDKLNARLMGAAPTGNGRRESYAHLPMPRMTNTYMLAGQSTPQEIIESVEYGIYAPNFGGGQVDITS
GKFVFSTSEAYLIENGKVTTPVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGT
A

Sequences:

>Translated_481_residues
MSLNLVSEQLLAANGLNHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAY
ADQISLLALEQSAQAARTIVRENGEGKVKTLAAVAHQPLYTTLDPLQSMSREEKLDILRRVDKAAREADKRVQEVNASLT
GVYELILVAATDGTLAADVRPLVRLSVSVQVEEDGKRERGASGGGGRFGYEYFLADLDGEVRADAWAKEAVRMALVNLSA
VAAPAGTLPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQIGEQVASALCTVVDDGTMMNRRGSVAIDDEGTPGQY
NVLIENGVLKGYMQDKLNARLMGAAPTGNGRRESYAHLPMPRMTNTYMLAGQSTPQEIIESVEYGIYAPNFGGGQVDITS
GKFVFSTSEAYLIENGKVTTPVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGT
A
>Mature_480_residues
SLNLVSEQLLAANGLNHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYA
DQISLLALEQSAQAARTIVRENGEGKVKTLAAVAHQPLYTTLDPLQSMSREEKLDILRRVDKAAREADKRVQEVNASLTG
VYELILVAATDGTLAADVRPLVRLSVSVQVEEDGKRERGASGGGGRFGYEYFLADLDGEVRADAWAKEAVRMALVNLSAV
AAPAGTLPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQIGEQVASALCTVVDDGTMMNRRGSVAIDDEGTPGQYN
VLIENGVLKGYMQDKLNARLMGAAPTGNGRRESYAHLPMPRMTNTYMLAGQSTPQEIIESVEYGIYAPNFGGGQVDITSG
KFVFSTSEAYLIENGKVTTPVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=481, Percent_Identity=94.3866943866944, Blast_Score=897, Evalue=0.0,
Organism=Escherichia coli, GI1790682, Length=410, Percent_Identity=21.9512195121951, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51288; Mature: 51156

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNLVSEQLLAANGLNHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSY
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEHHHEECCCCC
NIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRENGEGKVKTLAAVAHQPLY
CCCCCCCEEEECCCCCCCEECCCEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCH
TTLDPLQSMSREEKLDILRRVDKAAREADKRVQEVNASLTGVYELILVAATDGTLAADVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEEEEECCCCCHHCCC
PLVRLSVSVQVEEDGKRERGASGGGGRFGYEYFLADLDGEVRADAWAKEAVRMALVNLSA
EEEEEEEEEEECCCCCHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
VAAPAGTLPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQIGEQVASALCTVVDDG
HHCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCC
TMMNRRGSVAIDDEGTPGQYNVLIENGVLKGYMQDKLNARLMGAAPTGNGRRESYAHLPM
CEECCCCCEEECCCCCCCEEEEEEECCCHHHHHHHCCCEEEEECCCCCCCCCCCEECCCC
PRMTNTYMLAGQSTPQEIIESVEYGIYAPNFGGGQVDITSGKFVFSTSEAYLIENGKVTT
CCCCCEEEEECCCCHHHHHHHHHCCEECCCCCCCEEEEECCEEEEECCCEEEEECCEEEC
PVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGT
CCCCCEEECCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEEECCEECCCC
A
C
>Mature Secondary Structure 
SLNLVSEQLLAANGLNHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSY
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEHHHEECCCCC
NIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRENGEGKVKTLAAVAHQPLY
CCCCCCCEEEECCCCCCCEECCCEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCH
TTLDPLQSMSREEKLDILRRVDKAAREADKRVQEVNASLTGVYELILVAATDGTLAADVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEEEEECCCCCHHCCC
PLVRLSVSVQVEEDGKRERGASGGGGRFGYEYFLADLDGEVRADAWAKEAVRMALVNLSA
EEEEEEEEEEECCCCCHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
VAAPAGTLPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQIGEQVASALCTVVDDG
HHCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCC
TMMNRRGSVAIDDEGTPGQYNVLIENGVLKGYMQDKLNARLMGAAPTGNGRRESYAHLPM
CEECCCCCEEECCCCCCCEEEEEEECCCHHHHHHHCCCEEEEECCCCCCCCCCCEECCCC
PRMTNTYMLAGQSTPQEIIESVEYGIYAPNFGGGQVDITSGKFVFSTSEAYLIENGKVTT
CCCCCEEEEECCCCHHHHHHHHHCCEECCCCCCCEEEEECCEEEEECCCEEEEECCEEEC
PVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGT
CCCCCEEECCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEEECCEECCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]