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The map label for this gene is nanR [H]

Identifier: 29143590

GI number: 29143590

Start: 3349152

End: 3349943

Strand: Reverse

Name: nanR [H]

Synonym: t3257

Alternate gene names: 29143590

Gene position: 3349943-3349152 (Counterclockwise)

Preceding gene: 29143591

Following gene: 29143589

Centisome position: 69.91

GC content: 52.53

Gene sequence:

>792_bases
ATGGACGTTATGAACGCATTTGATTCGCAAGCAGAAGATTCACCGACATCCCTCGGGCGTAGTTTGCGCCGCCGCCCGCT
GGCGCGTAAAAAACTGTCTGAAATGGTTGAGGAAGAGCTGGAGCAGATGATCCGCCGTCATGAGTTTGGCGAGGGAGAAC
AGCTACCGTCTGAACGTGAATTAATGGCCTTCTTCAATGTGGGACGTCCCTCCGTGCGTGAAGCGTTAGCTGCGCTGAAG
CGTAAAGGTCTGGTGCAAATCAATAACGGCGAACGCGCCCGCGTCTCGCGCCCCTCTGCTGATACCATCATCAGCGAACT
GTCGGGTATGGCGAAAGATTTTCTTACTCATCCTGGCGGCATCGCTCACTTTGAACAGCTACGGCTTTTCTTTGAATCCA
GCCTGGTACGCTATGCGGCGGAACATGCCACCGACGAGCAGATCGCGTTGTTAACGAAAGCGCTGGAAATTAATAGCCAG
TCGCTGGATGACAACGCGCTGTTTATTCGTTCGGATGTCGAGTTTCACCGGGTGCTGGCTGAAATTCCCGGCAATCCGAT
CTTTATGGCTATTCATGTTGCTCTGCTGGACTGGCTAATCGCTGCTCGCCCAAGCGTTCCCGATCGTGAGCTGCATGAAC
ATAATAACGTGAGTTATCAACAGCATATTGTGATTGTTGATGCCATTCGCCAGCGAGATCCCGATAAAGCGGATCGCGCT
CTGCAAACCCACCTCAATAGCGTTTCCGCTACCTGGCACGCGCTCGGTAAAAAAAGTCAAAAAATGCGGTAG

Upstream 100 bases:

>100_bases
CCCTGAAGGGCCTGTTTTGTTTGGTCTCCTCGCGGGTTCACCCTGCTTTTGAAGCTGTGTTACGATAAGCTTGCTATTAT
TTGCCACCGACCACTCATGA

Downstream 100 bases:

>100_bases
CGATCGCACCTCCGATCCCGGTTTAGTGAAGCAGATCGCACTATAAGCGTTCTGTATTATTTGCTGCTTATTTGATCTGG
TATAACAGGTATAAAGGTAG

Product: transcriptional regulator NanR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MDVMNAFDSQAEDSPTSLGRSLRRRPLARKKLSEMVEEELEQMIRRHEFGEGEQLPSERELMAFFNVGRPSVREALAALK
RKGLVQINNGERARVSRPSADTIISELSGMAKDFLTHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIALLTKALEINSQ
SLDDNALFIRSDVEFHRVLAEIPGNPIFMAIHVALLDWLIAARPSVPDRELHEHNNVSYQQHIVIVDAIRQRDPDKADRA
LQTHLNSVSATWHALGKKSQKMR

Sequences:

>Translated_263_residues
MDVMNAFDSQAEDSPTSLGRSLRRRPLARKKLSEMVEEELEQMIRRHEFGEGEQLPSERELMAFFNVGRPSVREALAALK
RKGLVQINNGERARVSRPSADTIISELSGMAKDFLTHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIALLTKALEINSQ
SLDDNALFIRSDVEFHRVLAEIPGNPIFMAIHVALLDWLIAARPSVPDRELHEHNNVSYQQHIVIVDAIRQRDPDKADRA
LQTHLNSVSATWHALGKKSQKMR
>Mature_263_residues
MDVMNAFDSQAEDSPTSLGRSLRRRPLARKKLSEMVEEELEQMIRRHEFGEGEQLPSERELMAFFNVGRPSVREALAALK
RKGLVQINNGERARVSRPSADTIISELSGMAKDFLTHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIALLTKALEINSQ
SLDDNALFIRSDVEFHRVLAEIPGNPIFMAIHVALLDWLIAARPSVPDRELHEHNNVSYQQHIVIVDAIRQRDPDKADRA
LQTHLNSVSATWHALGKKSQKMR

Specific function: Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789621, Length=263, Percent_Identity=87.4524714828897, Blast_Score=474, Evalue=1e-135,
Organism=Escherichia coli, GI1789353, Length=232, Percent_Identity=24.1379310344828, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790780, Length=224, Percent_Identity=29.0178571428571, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 29803; Mature: 29803

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVMNAFDSQAEDSPTSLGRSLRRRPLARKKLSEMVEEELEQMIRRHEFGEGEQLPSERE
CCCHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADTIISELSGMAKDFLTHPGG
HHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
IAHFEQLRLFFESSLVRYAAEHATDEQIALLTKALEINSQSLDDNALFIRSDVEFHRVLA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHH
EIPGNPIFMAIHVALLDWLIAARPSVPDRELHEHNNVSYQQHIVIVDAIRQRDPDKADRA
HCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHH
LQTHLNSVSATWHALGKKSQKMR
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDVMNAFDSQAEDSPTSLGRSLRRRPLARKKLSEMVEEELEQMIRRHEFGEGEQLPSERE
CCCHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADTIISELSGMAKDFLTHPGG
HHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
IAHFEQLRLFFESSLVRYAAEHATDEQIALLTKALEINSQSLDDNALFIRSDVEFHRVLA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHH
EIPGNPIFMAIHVALLDWLIAARPSVPDRELHEHNNVSYQQHIVIVDAIRQRDPDKADRA
HCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHH
LQTHLNSVSATWHALGKKSQKMR
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA