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The map label for this gene is gatC [H]

Identifier: 29143516

GI number: 29143516

Start: 3271551

End: 3272924

Strand: Direct

Name: gatC [H]

Synonym: t3180

Alternate gene names: 29143516

Gene position: 3271551-3272924 (Clockwise)

Preceding gene: 29143515

Following gene: 29143517

Centisome position: 68.27

GC content: 55.09

Gene sequence:

>1374_bases
ATGTTTAGCGAAATAATGCGTTATATCCTCGACTTAGGCCCAACGGTGATGTTGCCTCTGGTGATCATCGTGTTCTCTAA
ACTGCTGGGAATGAAGCTTGGGGATTGTTTTAAATCGGGTTTGCATATTGGTATCGGCTTCGTGGGTATTGGTCTGGTCA
TCGGCCTGATGCTGGATTCTATCGGCCCCGCGGCGAAAGCCATGGCGGAACATTTCCAAATCAATCTCCACGTTATTGAC
GTCGGCTGGCCGGGTTCATCGCCCATGACCTGGGCGTCACAAATCGCGCTGGTCGCGATCCCTGTCGCCATCGGGGTTAA
CGTCCTGATGCTGGTGACCCGCATGACCCGCGTGGTGAATGTCGATATCTGGAATATCTGGCACATGACCTTCACGGGCG
CCATGCTGCATCTGGCGACCGGTTCATACTGGCTGGGGATTCTGGGCGTTGTGGTTCATGCCGCCTTTGTCTACAAACTG
GGGGACTGGTTTGCCAAAGATACCCGCGACTATTTTGGCCTCGAGGGGATTGCTATCCCACACGGCTCATCCGCGTACCT
GAGCCCCGTGGCGGTGCTCGTTGATACCATTATCGAGAAAATTCCGGGTCTCAATCGTATTCACTTTAGCGCAGACGATG
TCCAGAAACGCTTCGGACCGTTTGGCGAGCCGGTGACTGTCGGCTTCGTGATGGGGCTGGTGATTGGTGTACTGGCAGGC
TACGACACCAAAGCCGTTCTGCAACTGGCAGTCAAAACCGCAGCGGTGATGCTGCTTATGCCACGCGTCATTAAACCTAT
TATGGATGGCCTAACGCCTATCGCCAAACATGCGCGTAAACGTCTACAGGCCAAATTTGGCGGGCAGGAGTTCCTGATAG
GCCTTGATCCAGCGCTACTGCTCGGTCATACCTCTGTTGTCTCCGCGAGCCTGATATTCATTCCGCTGACCATCCTGATT
GCCGTCTTAGTACCGGGGAACCAGGTGCTGCCGTTCGGCGACCTCGCCACCATCGGTTTCTTTATTGCGATGGCGGTTGC
GGTACACCAGGGCAACCTGTTCCGCACGCTGATTTCAGGTGTCATTATTATGGGTATCACCCTGTGGATAGCCACGCAGA
CGATTGGCCTGCATACCCAACTGGCTGCCAATGCCGGAGCGCTAAAAGCTGGCGCACAAGTCGCCTCGCTGGATCAGGGC
GGTTCTCCCATCACCTGGCTGCTGATTCAACTTTTTACCTGGCAGAATATCGTCGGCTTCGCCGTCATTGCCATTATCTA
TCTGGCCGGCGTACTGCTGACCTGGCGTCGCGCCCGACAGTTTGTCGCGGCTGAGAAAGCCACGGCGCTACAGCAAAGTC
AAATCGCCTCTTAA

Upstream 100 bases:

>100_bases
CTTTGGCGATATTCCCGTCGTTCACGGTATGCCTTTTGTTTCCGGCGTGGGTATTGAAGCATTACAGCAAAAAATTCTGT
CCATTCTCATGGGGTAACGT

Downstream 100 bases:

>100_bases
TTTTAGGGGAGCAATCGCTCCCCTCACCTTCCTGGAGAATGTTATGAAATCAGTGGTTATTCACGCTGAGGGAGACGTGC
GCGTTGAAGAACGTCCCTTA

Product: PTS system galactitol-specific transporter subunit IIC

Products: galactitol-1-phosphate [Cytoplasm]; pyruvate [C]

Alternate protein names: EIIC-Gat; PTS system galactitol-specific EIIC component [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MFSEIMRYILDLGPTVMLPLVIIVFSKLLGMKLGDCFKSGLHIGIGFVGIGLVIGLMLDSIGPAAKAMAEHFQINLHVID
VGWPGSSPMTWASQIALVAIPVAIGVNVLMLVTRMTRVVNVDIWNIWHMTFTGAMLHLATGSYWLGILGVVVHAAFVYKL
GDWFAKDTRDYFGLEGIAIPHGSSAYLSPVAVLVDTIIEKIPGLNRIHFSADDVQKRFGPFGEPVTVGFVMGLVIGVLAG
YDTKAVLQLAVKTAAVMLLMPRVIKPIMDGLTPIAKHARKRLQAKFGGQEFLIGLDPALLLGHTSVVSASLIFIPLTILI
AVLVPGNQVLPFGDLATIGFFIAMAVAVHQGNLFRTLISGVIIMGITLWIATQTIGLHTQLAANAGALKAGAQVASLDQG
GSPITWLLIQLFTWQNIVGFAVIAIIYLAGVLLTWRRARQFVAAEKATALQQSQIAS

Sequences:

>Translated_457_residues
MFSEIMRYILDLGPTVMLPLVIIVFSKLLGMKLGDCFKSGLHIGIGFVGIGLVIGLMLDSIGPAAKAMAEHFQINLHVID
VGWPGSSPMTWASQIALVAIPVAIGVNVLMLVTRMTRVVNVDIWNIWHMTFTGAMLHLATGSYWLGILGVVVHAAFVYKL
GDWFAKDTRDYFGLEGIAIPHGSSAYLSPVAVLVDTIIEKIPGLNRIHFSADDVQKRFGPFGEPVTVGFVMGLVIGVLAG
YDTKAVLQLAVKTAAVMLLMPRVIKPIMDGLTPIAKHARKRLQAKFGGQEFLIGLDPALLLGHTSVVSASLIFIPLTILI
AVLVPGNQVLPFGDLATIGFFIAMAVAVHQGNLFRTLISGVIIMGITLWIATQTIGLHTQLAANAGALKAGAQVASLDQG
GSPITWLLIQLFTWQNIVGFAVIAIIYLAGVLLTWRRARQFVAAEKATALQQSQIAS
>Mature_457_residues
MFSEIMRYILDLGPTVMLPLVIIVFSKLLGMKLGDCFKSGLHIGIGFVGIGLVIGLMLDSIGPAAKAMAEHFQINLHVID
VGWPGSSPMTWASQIALVAIPVAIGVNVLMLVTRMTRVVNVDIWNIWHMTFTGAMLHLATGSYWLGILGVVVHAAFVYKL
GDWFAKDTRDYFGLEGIAIPHGSSAYLSPVAVLVDTIIEKIPGLNRIHFSADDVQKRFGPFGEPVTVGFVMGLVIGVLAG
YDTKAVLQLAVKTAAVMLLMPRVIKPIMDGLTPIAKHARKRLQAKFGGQEFLIGLDPALLLGHTSVVSASLIFIPLTILI
AVLVPGNQVLPFGDLATIGFFIAMAVAVHQGNLFRTLISGVIIMGITLWIATQTIGLHTQLAANAGALKAGAQVASLDQG
GSPITWLLIQLFTWQNIVGFAVIAIIYLAGVLLTWRRARQFVAAEKATALQQSQIAS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3775

COG function: function code G; Phosphotransferase system, galactitol-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788408, Length=446, Percent_Identity=85.4260089686099, Blast_Score=780, Evalue=0.0,
Organism=Escherichia coli, GI1790758, Length=395, Percent_Identity=44.8101265822785, Blast_Score=317, Evalue=9e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013853
- InterPro:   IPR013014
- InterPro:   IPR004703 [H]

Pfam domain/function: PF03611 EIIC-GAT [H]

EC number: NA

Molecular weight: Translated: 48998; Mature: 48998

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS00962 RIBOSOMAL_S2_1 ; PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSEIMRYILDLGPTVMLPLVIIVFSKLLGMKLGDCFKSGLHIGIGFVGIGLVIGLMLDS
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
IGPAAKAMAEHFQINLHVIDVGWPGSSPMTWASQIALVAIPVAIGVNVLMLVTRMTRVVN
CCHHHHHHHHHHEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VDIWNIWHMTFTGAMLHLATGSYWLGILGVVVHAAFVYKLGDWFAKDTRDYFGLEGIAIP
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEECC
HGSSAYLSPVAVLVDTIIEKIPGLNRIHFSADDVQKRFGPFGEPVTVGFVMGLVIGVLAG
CCCCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
YDTKAVLQLAVKTAAVMLLMPRVIKPIMDGLTPIAKHARKRLQAKFGGQEFLIGLDPALL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCHHHH
LGHTSVVSASLIFIPLTILIAVLVPGNQVLPFGDLATIGFFIAMAVAVHQGNLFRTLISG
HCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
VIIMGITLWIATQTIGLHTQLAANAGALKAGAQVASLDQGGSPITWLLIQLFTWQNIVGF
HHHHHHHHHHHHHHHCCHHHHHCCCCCHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHH
AVIAIIYLAGVLLTWRRARQFVAAEKATALQQSQIAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phosphoenolpyruvate; galactitol [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + galactitol [Periplasm] = galactitol-1-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]