| Definition | Salmonella enterica subsp. enterica serovar Typhi str. Ty2 chromosome, complete genome. |
|---|---|
| Accession | NC_004631 |
| Length | 4,791,961 |
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The map label for this gene is yghA [H]
Identifier: 29143420
GI number: 29143420
Start: 3159757
End: 3160641
Strand: Direct
Name: yghA [H]
Synonym: t3077
Alternate gene names: 29143420
Gene position: 3159757-3160641 (Clockwise)
Preceding gene: 29143419
Following gene: 29143424
Centisome position: 65.94
GC content: 56.5
Gene sequence:
>885_bases ATGTCTCATCTATACGACCCTACCACGCAGTATTACACCGGCGAGTATCCTAAGCAAAAACAGCCGGCGCCCGGCGTCCA GGCGAAAATGACGCCTGTTCCTGACTGTGGTGAAAAAAGTTATGTCGGCAGTGGTCGCCTTAAAGATCGTAAGGCGCTGG TGACAGGGGGCGACTCCGGGATTGGGCGCGCTGCCGCTATCGCTTACGCGCGTGAAGGCACAGATGTCGCGATCAACTAT CTGCCAGCGGAAGAAGAGGACGCCCAGCAGGTTAAAGCGCTGATTGAGGAGTGCGGCCGTAAAGCGGTGTTATTGCCGGG CGATCTTAGCGACGAATCTTTCGCCCGTTCGCTGGTCCATAAGGCGCGCGAAGCGCTGGGCGGGCTGGACATTCTGGCGC TGGTAGCCGGTAAACAGACGGCAATCCCGGAGATAAAAGATCTAACCAGCGAGCAATTTCAGCAAACCTTCGCCGTTAAC GTTTTTGCCCTGTTCTGGATAACCCAGGAAGCGATTCCGCTGCTGCCAAAAGGCGCCAGTATTATCACAACGTCGTCTAT CCAGGCCTATCAGCCCAGTCCGCACCTGCTGGATTATGCGGCAACCAAGGCGGCAATCCTTAATTACAGCCGCGGCCTGG CGAAACAGGTGGCGGAAAAAGGAATTCGCGTGAATATTGTCGCGCCTGGCCCTATCTGGACAGCGCTGCAAATTTCCGGC GGCCAAACACAGGATAAAATTCCGCAGTTTGGCCAGCAGACGCCAATGAAGCGGGCCGGTCAACCGGCAGAGCTGGCGCC GGTGTATGTCTATCTGGCAAGCCAGGAATCAAGTTACGTTACCGCAGAAGTGCACGGCGTGTGCGGCGGGGAACATTTAG GCTAA
Upstream 100 bases:
>100_bases TGTGAATACGGGCGAAGCATAAGGATCGTTCTGATTCTCCCTCTTACGGTAGTAAAAGTGTCTACGCTTAAAGGGTGTTC AACCTGAAGGGAGAAGCTCA
Downstream 100 bases:
>100_bases CGCATGAAGTCGATTAAGGTGGCGCAATTCTGTTAAGCAAGGCGCCATCTTAGGCAATAAAAAAGCCGGGTGGCGACTTC GCCTTACCCGGCCTACAGCA
Product: oxidoreductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 294; Mature: 293
Protein sequence:
>294_residues MSHLYDPTTQYYTGEYPKQKQPAPGVQAKMTPVPDCGEKSYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGTDVAINY LPAEEEDAQQVKALIEECGRKAVLLPGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVN VFALFWITQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG GQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG
Sequences:
>Translated_294_residues MSHLYDPTTQYYTGEYPKQKQPAPGVQAKMTPVPDCGEKSYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGTDVAINY LPAEEEDAQQVKALIEECGRKAVLLPGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVN VFALFWITQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG GQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG >Mature_293_residues SHLYDPTTQYYTGEYPKQKQPAPGVQAKMTPVPDCGEKSYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGTDVAINYL PAEEEDAQQVKALIEECGRKAVLLPGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNV FALFWITQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISGG QTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=30.4878048780488, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=29.6747967479675, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=30.7692307692308, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=29.0322580645161, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=27.0992366412214, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=31.9371727748691, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI59889578, Length=198, Percent_Identity=29.2929292929293, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=26.984126984127, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=28.4584980237154, Blast_Score=71, Evalue=2e-12, Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=29.5081967213115, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI32455239, Length=182, Percent_Identity=28.021978021978, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI5031765, Length=182, Percent_Identity=28.021978021978, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI109715829, Length=249, Percent_Identity=28.5140562248996, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1789378, Length=294, Percent_Identity=92.8571428571429, Blast_Score=565, Evalue=1e-162, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=36.5853658536585, Blast_Score=136, Evalue=2e-33, Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=31.7073170731707, Blast_Score=107, Evalue=8e-25, Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=31.9838056680162, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=30.8943089430894, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=29.7959183673469, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=28.8461538461538, Blast_Score=98, Evalue=7e-22, Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=28.1124497991968, Blast_Score=92, Evalue=5e-20, Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=27.2, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=27.6422764227642, Blast_Score=84, Evalue=8e-18, Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=27.34375, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI1787526, Length=240, Percent_Identity=32.5, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1786701, Length=211, Percent_Identity=28.9099526066351, Blast_Score=67, Evalue=2e-12, Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=30.6451612903226, Blast_Score=101, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=30.4, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=30.4832713754647, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=30.4511278195489, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=28.5171102661597, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=30.1587301587302, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=30.9433962264151, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17562904, Length=251, Percent_Identity=29.8804780876494, Blast_Score=95, Evalue=5e-20, Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=30.1526717557252, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17551412, Length=281, Percent_Identity=28.8256227758007, Blast_Score=94, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=33.2075471698113, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=30.4511278195489, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=30.3703703703704, Blast_Score=91, Evalue=8e-19, Organism=Caenorhabditis elegans, GI17538480, Length=252, Percent_Identity=28.968253968254, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=28.4, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=30.6201550387597, Blast_Score=89, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17563726, Length=248, Percent_Identity=29.8387096774194, Blast_Score=88, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17544670, Length=253, Percent_Identity=28.0632411067194, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17508651, Length=254, Percent_Identity=28.740157480315, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=31.8181818181818, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17538182, Length=247, Percent_Identity=31.1740890688259, Blast_Score=80, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=29.6296296296296, Blast_Score=79, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=28.1954887218045, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17555706, Length=259, Percent_Identity=28.957528957529, Blast_Score=78, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=32.8205128205128, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=28.8389513108614, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=27.3809523809524, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=23.5294117647059, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=246, Percent_Identity=25.2032520325203, Blast_Score=70, Evalue=3e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=27.5193798449612, Blast_Score=64, Evalue=3e-11, Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=31.6205533596838, Blast_Score=108, Evalue=5e-24, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=30.4, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=30.952380952381, Blast_Score=98, Evalue=7e-21, Organism=Drosophila melanogaster, GI21355319, Length=240, Percent_Identity=28.75, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=28.740157480315, Blast_Score=92, Evalue=5e-19, Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=30.859375, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI17737361, Length=268, Percent_Identity=27.2388059701493, Blast_Score=84, Evalue=2e-16, Organism=Drosophila melanogaster, GI24644337, Length=118, Percent_Identity=34.7457627118644, Blast_Score=74, Evalue=8e-14, Organism=Drosophila melanogaster, GI24643142, Length=238, Percent_Identity=30.2521008403361, Blast_Score=74, Evalue=8e-14, Organism=Drosophila melanogaster, GI24584748, Length=210, Percent_Identity=30, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI161076933, Length=210, Percent_Identity=30, Blast_Score=67, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 31469; Mature: 31338
Theoretical pI: Translated: 6.36; Mature: 6.36
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 1.0 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 0.7 %Met (Mature Protein) 1.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSHLYDPTTQYYTGEYPKQKQPAPGVQAKMTPVPDCGEKSYVGSGRLKDRKALVTGGDSG CCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCC IGRAAAIAYAREGTDVAINYLPAEEEDAQQVKALIEECGRKAVLLPGDLSDESFARSLVH CCHHHHHEECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH KAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNVFALFWITQEAIPLLPKGAS HHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE IITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG EEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECC GQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG CCCHHHHHHHCCCCCHHHCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCC >Mature Secondary Structure SHLYDPTTQYYTGEYPKQKQPAPGVQAKMTPVPDCGEKSYVGSGRLKDRKALVTGGDSG CCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCC IGRAAAIAYAREGTDVAINYLPAEEEDAQQVKALIEECGRKAVLLPGDLSDESFARSLVH CCHHHHHEECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH KAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNVFALFWITQEAIPLLPKGAS HHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE IITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG EEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECC GQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG CCCHHHHHHHCCCCCHHHCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]