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The map label for this gene is speA [H]

Identifier: 29143349

GI number: 29143349

Start: 3090106

End: 3092082

Strand: Reverse

Name: speA [H]

Synonym: t2999

Alternate gene names: 29143349

Gene position: 3092082-3090106 (Counterclockwise)

Preceding gene: 29143350

Following gene: 29143348

Centisome position: 64.53

GC content: 55.89

Gene sequence:

>1977_bases
ATGTCTGACGACATGTCTATGGGTTCGCCTTCGTCAGCAGGCGAACAGGGTGTACTACGCTCCATGCAGGAGGTTGCAAT
GAGCTCCCAGGAAGCCAGCAAGATGCTGCGCACTTACAATATTGCCTGGTGGGGCAATAACTACTACGACGTCAACGAGC
TGGGCCATATTAGCGTATGCCCCGATCCCGACGTACCGGAAGCGCGTGTCGATCTTGCCAAACTGGTGAAAGCGCGCGAA
GCGCAAGGTCAGCGTCTGCCGGCGCTGTTCTGCTTCCCGCAGATCCTGCAACACCGTTTGCGTTCAATTAACGCGGCGTT
TAAGCGTGCGCGTGAATCTTACGGTTATAACGGCGACTACTTCCTCGTTTATCCGATTAAGGTCAATCAGCATCGCCGCG
TGATCGAGTCCCTTATCCATTCCGGTGAACCGTTGGGGCTGGAAGCGGGGTCGAAAGCGGAATTGATGGCGGTGCTGGCG
CATGCCGGCATGACCCGTAGCGTGATCGTCTGTAATGGTTATAAAGACCGTGAATATATTCGGCTGGCGCTGATTGGCGA
GAAGATGGGCCATAAGGTTTATCTGGTCATCGAAAAGATGTCTGAAATCGCGATTGTGCTGGAAGAGGCCGAGCGCCTGA
ACGTGGTTCCTCGCCTGGGCGTGCGTGCGCGTCTGGCCTCTCAGGGGTCCGGTAAGTGGCAATCCTCCGGCGGCGAAAAA
TCAAAATTCGGCCTGGCGGCGACGCAGGTGCTGCAACTGGTGGAGACCCTGCGTGACGCTGGGCGTCTGGACAGTCTGCA
ACTGTTGCACTTCCACCTGGGATCGCAGATGGCGAACATTCGCGATATCGCGACCGGCGTGCGCGAGTCCGCGCGTTTCT
ATGTTGAGCTGCATAAGCTGGGCGTTAATATCCAGTGCTTCGACGTGGGCGGCGGTCTGGGCGTGGATTATGAAGGTACC
CGCTCGCAGTCCGACTGTTCGGTGAACTATGGCCTGAACGAATATGCCAATAACATCATCTGGGCGATTGGCGATGCCTG
CGAAGAGCATGGTTTACCGCATCCGACGGTGATTACCGAGTCTGGGCGCGCCGTCACTGCGCACCATACGGTACTGGTCT
CTAACATTATCGGCGTGGAGCGTAACGAATACACGGATCCGACCGCCCCTGCTGAAGATGCGCCGCGCGCGCTGCAAAAT
CTGTGGGAAACCTGGCAGGAGATGCATAAGCCTGGCACCCGCCGCTCGCTGCGTGAATGGCTGCATGATAGCCAAATGGA
TCTGCACGATATTCATATCGGCTACTCTTCCGGCGCGTTTAGTTTGCAGGAGCGCGCCTGGGCGGAGCAACTTTATCTCA
GCATGTGCCATGAAGTGCAGAAGCAACTGGACCCGCAAAACCGTGCGCATCGCCCGATTATCGACGAACTGCAAGAGCGG
ATGGCGGACAAAATGTACGTCAACTTCTCGCTGTTCCAGTCGATGCCGGACGCGTGGGGAATCGATCAGCTCTTTCCGGT
GCTGCCGCTGGAAGGGTTAGATCAGGTACCGGAACGTCGTGCCGTGCTGCTGGATATTACCTGTGATTCCGATGGCGCTA
TCGACCACTATATCGATGGCGACGGTATCGCCACGACGATGCCGATGCCGGAATACGATCCAGAGAATCCGCCGATGCTC
GGCTTCTTTATGGTCGGCGCCTATCAGGAGATCCTCGGTAACATGCACAACCTGTTTGGCGATACTGAAGCGGTTGACGT
GTTTGTCTTCCCGGATGGTAGTGTCGAGGTTGAGTTGTCGGACGAAGGCGATACCGTTGCGGATATGCTGCAATATGTGC
AACTGGATCCGAAAACGCTATTAACGCATTTCCGCGACCAGGTAAAACAGACGGATCTGGACGATGCGTTGCAGCAGCAG
TTCCTTGAGGAATTTGAAGCGGGACTGTACGGTTATACTTATCTTGAAGATGAGTAG

Upstream 100 bases:

>100_bases
ATCTGCTGGAAAATCCGCTTGTCTATGGGTTGTTATCGCGTCTTCGGATTGCGATAGTAGTCAACTGTTTTACACTTGCT
AATAAAAATTGAGGTTCGCT

Downstream 100 bases:

>100_bases
CCGTTGATGCCCGGCGGCGCTGCGCTTACCGGGCCTACGAATGCAGGCTGGATAAGGTAAAGCCGCCACCCGGCAGAATG
CTATACTCACTTGAACCCGT

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 658; Mature: 657

Protein sequence:

>658_residues
MSDDMSMGSPSSAGEQGVLRSMQEVAMSSQEASKMLRTYNIAWWGNNYYDVNELGHISVCPDPDVPEARVDLAKLVKARE
AQGQRLPALFCFPQILQHRLRSINAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLA
HAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLEEAERLNVVPRLGVRARLASQGSGKWQSSGGEK
SKFGLAATQVLQLVETLRDAGRLDSLQLLHFHLGSQMANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGT
RSQSDCSVNYGLNEYANNIIWAIGDACEEHGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTDPTAPAEDAPRALQN
LWETWQEMHKPGTRRSLREWLHDSQMDLHDIHIGYSSGAFSLQERAWAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQER
MADKMYVNFSLFQSMPDAWGIDQLFPVLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPML
GFFMVGAYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTHFRDQVKQTDLDDALQQQ
FLEEFEAGLYGYTYLEDE

Sequences:

>Translated_658_residues
MSDDMSMGSPSSAGEQGVLRSMQEVAMSSQEASKMLRTYNIAWWGNNYYDVNELGHISVCPDPDVPEARVDLAKLVKARE
AQGQRLPALFCFPQILQHRLRSINAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLA
HAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLEEAERLNVVPRLGVRARLASQGSGKWQSSGGEK
SKFGLAATQVLQLVETLRDAGRLDSLQLLHFHLGSQMANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGT
RSQSDCSVNYGLNEYANNIIWAIGDACEEHGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTDPTAPAEDAPRALQN
LWETWQEMHKPGTRRSLREWLHDSQMDLHDIHIGYSSGAFSLQERAWAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQER
MADKMYVNFSLFQSMPDAWGIDQLFPVLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPML
GFFMVGAYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTHFRDQVKQTDLDDALQQQ
FLEEFEAGLYGYTYLEDE
>Mature_657_residues
SDDMSMGSPSSAGEQGVLRSMQEVAMSSQEASKMLRTYNIAWWGNNYYDVNELGHISVCPDPDVPEARVDLAKLVKAREA
QGQRLPALFCFPQILQHRLRSINAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLAH
AGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLEEAERLNVVPRLGVRARLASQGSGKWQSSGGEKS
KFGLAATQVLQLVETLRDAGRLDSLQLLHFHLGSQMANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTR
SQSDCSVNYGLNEYANNIIWAIGDACEEHGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTDPTAPAEDAPRALQNL
WETWQEMHKPGTRRSLREWLHDSQMDLHDIHIGYSSGAFSLQERAWAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQERM
ADKMYVNFSLFQSMPDAWGIDQLFPVLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLG
FFMVGAYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTHFRDQVKQTDLDDALQQQF
LEEFEAGLYGYTYLEDE

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=658, Percent_Identity=97.5683890577508, Blast_Score=1336, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 73834; Mature: 73703

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00878 ODR_DC_2_1 ; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDMSMGSPSSAGEQGVLRSMQEVAMSSQEASKMLRTYNIAWWGNNYYDVNELGHISVC
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECCCCCEEEEC
PDPDVPEARVDLAKLVKAREAQGQRLPALFCFPQILQHRLRSINAAFKRARESYGYNGDY
CCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
FLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLAHAGMTRSVIVCNGYKDREYI
EEEEEEEECHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEE
RLALIGEKMGHKVYLVIEKMSEIAIVLEEAERLNVVPRLGVRARLASQGSGKWQSSGGEK
EEEEEHHHHCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCC
SKFGLAATQVLQLVETLRDAGRLDSLQLLHFHLGSQMANIRDIATGVRESARFYVELHKL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHH
GVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNIIWAIGDACEEHGLPHPTVITE
CCEEEEEECCCCCCCCCCCCCCCCCCEEECCHHHHHCCEEEEECHHHHHCCCCCCEEEEC
SGRAVTAHHTVLVSNIIGVERNEYTDPTAPAEDAPRALQNLWETWQEMHKPGTRRSLREW
CCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LHDSQMDLHDIHIGYSSGAFSLQERAWAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQER
HCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
MADKMYVNFSLFQSMPDAWGIDQLFPVLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDG
HHHHHEEEHHHHHCCCCCCCHHHHHHCCCCCCHHCCCCCCEEEEEEEECCCCCEEEEECC
DGIATTMPMPEYDPENPPMLGFFMVGAYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELS
CCCEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEC
DEGDTVADMLQYVQLDPKTLLTHFRDQVKQTDLDDALQQQFLEEFEAGLYGYTYLEDE
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCC
>Mature Secondary Structure 
SDDMSMGSPSSAGEQGVLRSMQEVAMSSQEASKMLRTYNIAWWGNNYYDVNELGHISVC
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECCCCCEEEEC
PDPDVPEARVDLAKLVKAREAQGQRLPALFCFPQILQHRLRSINAAFKRARESYGYNGDY
CCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
FLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLAHAGMTRSVIVCNGYKDREYI
EEEEEEEECHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEE
RLALIGEKMGHKVYLVIEKMSEIAIVLEEAERLNVVPRLGVRARLASQGSGKWQSSGGEK
EEEEEHHHHCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCC
SKFGLAATQVLQLVETLRDAGRLDSLQLLHFHLGSQMANIRDIATGVRESARFYVELHKL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHH
GVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNIIWAIGDACEEHGLPHPTVITE
CCEEEEEECCCCCCCCCCCCCCCCCCEEECCHHHHHCCEEEEECHHHHHCCCCCCEEEEC
SGRAVTAHHTVLVSNIIGVERNEYTDPTAPAEDAPRALQNLWETWQEMHKPGTRRSLREW
CCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LHDSQMDLHDIHIGYSSGAFSLQERAWAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQER
HCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
MADKMYVNFSLFQSMPDAWGIDQLFPVLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDG
HHHHHEEEHHHHHCCCCCCCHHHHHHCCCCCCHHCCCCCCEEEEEEEECCCCCEEEEECC
DGIATTMPMPEYDPENPPMLGFFMVGAYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELS
CCCEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEC
DEGDTVADMLQYVQLDPKTLLTHFRDQVKQTDLDDALQQQFLEEFEAGLYGYTYLEDE
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12384590; 12704152 [H]