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The map label for this gene is sdaB [H]

Identifier: 29143233

GI number: 29143233

Start: 2963552

End: 2964919

Strand: Direct

Name: sdaB [H]

Synonym: t2879

Alternate gene names: 29143233

Gene position: 2963552-2964919 (Clockwise)

Preceding gene: 29143232

Following gene: 29143234

Centisome position: 61.84

GC content: 55.99

Gene sequence:

>1368_bases
ATGATTAGCGTATTCGATATTTTTAAAATCGGCATTGGCCCTTCCAGTTCTCACACCGTCGGACCAATGAAAGCAGGCAA
GCAGTTCACGGACGATCTGATTGCCCGCCATATTCTTACAGATGTCACCCGCGTCGTGGTGGATGTCTACGGCTCTCTGT
CATTGACGGGTAAAGGCCACCACACTGATATCGCCATTATTATGGGCCTGGCGGGGAATCTGCCGGACACCGTCGATATC
GACGCCATTCCGTCCTTTATCCAGGATGTGAACACCCATGGGCGTTTACTACTGGCCAATGGGCAGCATGAAGTCGAATT
TCCGGTCGATAAGTGCATGAATTTCCACGCCGACAACCTGTCTCTGCATGAGAACGGGATGCGTATTACCGCGCTGGCGG
GCAATAAAGTGCTCTACAGCCAAACCTACTACTCCATTGGCGGCGGCTTTATCGTCGATGAAGAGCACTTTGGTTTGACA
AATAGCGAACCCGTTAACGTACCGTATCCTTATAAAACCGCCGCGGATTTACAGCGCCATTGCCAGGAGACGGGTCTGTC
GCTCTCCGGTCTGATGATGCAAAACGAACTGGCTCTGCACAGTAAAGAAGCGCTGGAGCAGCACTTCGCCAAGGTCTGGG
AGGTGATGCGCAGCGGTATTGAGCGCGGTATCACCACCGAGGGCGTATTGCCGGGCAAACTGCGCGTTCCGCGTCGCGCG
GCGGCGCTGCGTCGGATGCTGGTCAGTCAGGATAAGACCACCACCGATCCGATGGCGGTCGTCGACTGGATCAATATGTT
CGCGCTGGCGGTGAACGAAGAGAATGCCGCAGGCGGACGAGTAGTCACTGCCCCGACTAACGGCGCATGTGGTATTGTGC
CGGCGGTGCTGGCGTACTATGACAAATTTATCCGCGAAGTAAATGCTAACTCACTTGCTCGCTATATGCTGGTCGCCAGC
GCGATTGGCTCGCTGTATAAGATGAACGCCTCTATTTCCGGCGCCGAAGTGGGTTGTCAGGGAGAGGTCGGCGTGGCCTG
TTCCATGGCGGCAGCGGGTCTGGCCGAGCTGCTGGGCGGTAGTCCGGCGCAGGTGTGTATCGCCGCAGAAATCGCCATGG
AGCATAATCTGGGGCTAACTTGCGATCCGGTTGCCGGTCAGGTCCAGGTTCCCTGCATTGAGCGTAACGCGATTGCTTCA
GTCAAAGCGGTCAACGCCGCGCGTATGGCGCTGCGCCGAACCAGCGAACCGCGCGTATGCCTCGATAAAGTGATTGAGAC
CATGTACGAAACCGGTAAAGACATGAACGCTAAGTACCGCGAAACTTCGCGCGGCGGCCTGGCGATGAAGATCGTTACCT
GCGATTAA

Upstream 100 bases:

>100_bases
CTGATTGCCATCTCCGCTATTTTCTACTCACTGTTCAGCTAAGTCCTTTAGCGCCGCTTACCGCGGCGCTTCTCTATGAT
ACAACCGCAATGGATGCCCT

Downstream 100 bases:

>100_bases
TTCTCAGCACATTTTAGGATCTGTAGGCCGGATAAGGCGCTCGCCGCCATCCGGCTTTTGTTGCCTGATGGCGCTTCGCT
TATCAGGTCTACGGATAGCG

Product: L-serine dehydratase 2

Products: NA

Alternate protein names: SDH 2; L-serine deaminase 2; L-SD2 [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARHILTDVTRVVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDI
DAIPSFIQDVNTHGRLLLANGQHEVEFPVDKCMNFHADNLSLHENGMRITALAGNKVLYSQTYYSIGGGFIVDEEHFGLT
NSEPVNVPYPYKTAADLQRHCQETGLSLSGLMMQNELALHSKEALEQHFAKVWEVMRSGIERGITTEGVLPGKLRVPRRA
AALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYYDKFIREVNANSLARYMLVAS
AIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGGSPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPCIERNAIAS
VKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMKIVTCD

Sequences:

>Translated_455_residues
MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARHILTDVTRVVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDI
DAIPSFIQDVNTHGRLLLANGQHEVEFPVDKCMNFHADNLSLHENGMRITALAGNKVLYSQTYYSIGGGFIVDEEHFGLT
NSEPVNVPYPYKTAADLQRHCQETGLSLSGLMMQNELALHSKEALEQHFAKVWEVMRSGIERGITTEGVLPGKLRVPRRA
AALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYYDKFIREVNANSLARYMLVAS
AIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGGSPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPCIERNAIAS
VKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMKIVTCD
>Mature_455_residues
MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARHILTDVTRVVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDI
DAIPSFIQDVNTHGRLLLANGQHEVEFPVDKCMNFHADNLSLHENGMRITALAGNKVLYSQTYYSIGGGFIVDEEHFGLT
NSEPVNVPYPYKTAADLQRHCQETGLSLSGLMMQNELALHSKEALEQHFAKVWEVMRSGIERGITTEGVLPGKLRVPRRA
AALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYYDKFIREVNANSLARYMLVAS
AIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGGSPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPCIERNAIAS
VKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMKIVTCD

Specific function: Deaminates also threonine, particularly when it is present in high concentration [H]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=455, Percent_Identity=94.0659340659341, Blast_Score=896, Evalue=0.0,
Organism=Escherichia coli, GI1788116, Length=455, Percent_Identity=77.3626373626374, Blast_Score=734, Evalue=0.0,
Organism=Escherichia coli, GI48994925, Length=452, Percent_Identity=72.787610619469, Blast_Score=677, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 48882; Mature: 48882

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARHILTDVTRVVVDVYGSLSLTGKGH
CCCCEEEEEECCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCC
HTDIAIIMGLAGNLPDTVDIDAIPSFIQDVNTHGRLLLANGQHEVEFPVDKCMNFHADNL
CCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCEECCHHHHCCCCCCCC
SLHENGMRITALAGNKVLYSQTYYSIGGGFIVDEEHFGLTNSEPVNVPYPYKTAADLQRH
EEECCCEEEEEEECCEEEEEEHHEECCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHH
CQETGLSLSGLMMQNELALHSKEALEQHFAKVWEVMRSGIERGITTEGVLPGKLRVPRRA
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
AALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYY
HHHHHHHHHCCCCCCCHHHHHHHHHHHEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHH
DKFIREVNANSLARYMLVASAIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGG
HHHHHHHCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPCIERNAIASVKAVNAARMALRRTSEPRVC
CCHHEEEEEEHHHHCCCCCEECCCCCCEECCEECCCHHHHHHHHHHHHHHHHCCCCCHHH
LDKVIETMYETGKDMNAKYRETSRGGLAMKIVTCD
HHHHHHHHHHCCCCCCCHHHHCCCCCEEEEEEECC
>Mature Secondary Structure
MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARHILTDVTRVVVDVYGSLSLTGKGH
CCCCEEEEEECCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCC
HTDIAIIMGLAGNLPDTVDIDAIPSFIQDVNTHGRLLLANGQHEVEFPVDKCMNFHADNL
CCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCEECCHHHHCCCCCCCC
SLHENGMRITALAGNKVLYSQTYYSIGGGFIVDEEHFGLTNSEPVNVPYPYKTAADLQRH
EEECCCEEEEEEECCEEEEEEHHEECCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHH
CQETGLSLSGLMMQNELALHSKEALEQHFAKVWEVMRSGIERGITTEGVLPGKLRVPRRA
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
AALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYY
HHHHHHHHHCCCCCCCHHHHHHHHHHHEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHH
DKFIREVNANSLARYMLVASAIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGG
HHHHHHHCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPCIERNAIASVKAVNAARMALRRTSEPRVC
CCHHEEEEEEHHHHCCCCCEECCCCCCEECCEECCCHHHHHHHHHHHHHHHHCCCCCHHH
LDKVIETMYETGKDMNAKYRETSRGGLAMKIVTCD
HHHHHHHHHHCCCCCCCHHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8385012; 9278503 [H]