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The map label for this gene is invG [H]

Identifier: 29143159

GI number: 29143159

Start: 2879454

End: 2881142

Strand: Reverse

Name: invG [H]

Synonym: t2800

Alternate gene names: 29143159

Gene position: 2881142-2879454 (Counterclockwise)

Preceding gene: 29143160

Following gene: 29143158

Centisome position: 60.12

GC content: 46.36

Gene sequence:

>1689_bases
ATGAAGACACATATTCTTTTGGCCAGAGTGCTGGCATGTGCCGCGCTTGTTCTGGTTGCACCTGGTTATTCTAGTGAAAA
AATACCTGTAACGGGAAGTGGGTTTGTTGCGAAAGACGATAGCCTGCGGACATTTTTCGATGCCATGGCGCTACAGCTAA
AGGAGCCTGTCATTGTTAGCAAAATGGCGGCACGAAAAAAAATTACGGGCAACTTTGAGTTTCACGATCCTAACGCATTA
CTGGAGAAGCTTTCCCTACAACTGGGGCTGATTTGGTATTTCGATGGGCAGGCTATCTATATTTATGACGCCAGTGAAAT
GCGCAATGCCGTGGTTTCTTTACGCAACGTCTCACTCAATGAGTTCAACAATTTTCTAAAACGCTCAGGTTTATATAACA
AAAATTACCCGCTACGTGGCGATAACCGTAAAGGAACATTCTATGTTTCAGGGCCACCCGTCTATGTTGATATGGTGGTC
AACGCCGCCACCATGATGGACAAGCAAAACGATGGTATTGAGCTGGGACGCCAGAAAATAGGGGTGATGCGTCTGAACAA
TACCTTCGTGGGCGATCGTACCTACAATCTGCGCGATCAGAAAATGGTTATTCCCGGTATTGCTACGGCCATTGAAAGGT
TATTGCAGGGAGAAGAGCAACCCTTAGGTAATATTGTCAGTAGCGAACCCCCGGCGATGCCAGCATTTTCAGCGAATGGA
GAAAAAGGTAAAGCAGCAAATTATGCCGGTGGCATGAGTCTGCAGGAAGCTTTAAAGCAAAATGCCGCGGCGGGCAATAT
TAAAATCGTGGCCTATCCGGATACCAACAGTTTGTTAGTAAAGGGAACGGCTGGGCAGGTGCATTTTATCGAAATGCTGG
TTAAAGCGCTGGATGTCGCCAAACGTCACGTAGAATTATCCCTGTGGATTGTCGATCTTAATAAAAGCGATCTGGAGCGT
TTGGGCACTTCATGGAGCGGCAGCATAACTATTGGGGACAAACTTGGCGTGTCATTAAACCAGTCTTCAATAAGTACCCT
CGATGGCAGTCGATTCATCGCCGCGGTCAATGCGTTAGAAGAGAAGAAACAGGCGACGGTGGTTTCGCGTCCGGTATTAC
TGACTCAGGAAAATGTTCCCGCTATTTTTGATAACAACAGAACGTTTTACACCAAGCTGATTGGGGAACGTAATGTGGCG
CTTGAGCATGTAACATACGGAACAATGATCCGAGTGCTGCCCCGTTTTTCCGCAGATGGTCAGATAGAAATGTCGCTGGA
CATTGAAGATGGCAACGATAAGACGCCGCAATCCGATACTACCACCTCCGTAGATGCGTTACCCGAAGTCGGGCGAACGT
TAATTAGCACTATTGCAAGAGTTCCGCACGGAAAAAGTTTGCTGGTCGGTGGTTATACACGGGATGCAAATACCGATACT
GTCCAAAGTATTCCGGTTTTAGGCAAATTACCGCTTATTGGTAGCCTGTTCCGTTATTCCAGTAAGAATAAAAGTAATGT
TGTTCGTGTGTTCATGATTGAACCAAAAGAAATTGTCGACCCGTTAACGCCGGATGCCAGCGAATCGGTAAACAATATTC
TGAAGCAAAGCGGTGCCTGGAGTGGGGACGATAAGTTACAGAAATGGGTTCGTGTTTATCTGGATAGAGGTCAGGAGGTA
ATTAAATGA

Upstream 100 bases:

>100_bases
ATCATGGTTACTCATCGCCTTCACATTTTTCTAGTGAGATCAAAGAGCTGATCGGCGTTTCGCCGCGGAAATTATCAAAT
ATTATTCAATTGGCAGACAA

Downstream 100 bases:

>100_bases
TTCCTGGCTCAACCTCTGGTATTTCATTTTCCAGAATATTGTCCCGGCAGGCATCTCATCAGGATGCGACCCAACATACT
GATGCGCAACAGGCGGAAAT

Product: virulence-associated secretory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MKTHILLARVLACAALVLVAPGYSSEKIPVTGSGFVAKDDSLRTFFDAMALQLKEPVIVSKMAARKKITGNFEFHDPNAL
LEKLSLQLGLIWYFDGQAIYIYDASEMRNAVVSLRNVSLNEFNNFLKRSGLYNKNYPLRGDNRKGTFYVSGPPVYVDMVV
NAATMMDKQNDGIELGRQKIGVMRLNNTFVGDRTYNLRDQKMVIPGIATAIERLLQGEEQPLGNIVSSEPPAMPAFSANG
EKGKAANYAGGMSLQEALKQNAAAGNIKIVAYPDTNSLLVKGTAGQVHFIEMLVKALDVAKRHVELSLWIVDLNKSDLER
LGTSWSGSITIGDKLGVSLNQSSISTLDGSRFIAAVNALEEKKQATVVSRPVLLTQENVPAIFDNNRTFYTKLIGERNVA
LEHVTYGTMIRVLPRFSADGQIEMSLDIEDGNDKTPQSDTTTSVDALPEVGRTLISTIARVPHGKSLLVGGYTRDANTDT
VQSIPVLGKLPLIGSLFRYSSKNKSNVVRVFMIEPKEIVDPLTPDASESVNNILKQSGAWSGDDKLQKWVRVYLDRGQEV
IK

Sequences:

>Translated_562_residues
MKTHILLARVLACAALVLVAPGYSSEKIPVTGSGFVAKDDSLRTFFDAMALQLKEPVIVSKMAARKKITGNFEFHDPNAL
LEKLSLQLGLIWYFDGQAIYIYDASEMRNAVVSLRNVSLNEFNNFLKRSGLYNKNYPLRGDNRKGTFYVSGPPVYVDMVV
NAATMMDKQNDGIELGRQKIGVMRLNNTFVGDRTYNLRDQKMVIPGIATAIERLLQGEEQPLGNIVSSEPPAMPAFSANG
EKGKAANYAGGMSLQEALKQNAAAGNIKIVAYPDTNSLLVKGTAGQVHFIEMLVKALDVAKRHVELSLWIVDLNKSDLER
LGTSWSGSITIGDKLGVSLNQSSISTLDGSRFIAAVNALEEKKQATVVSRPVLLTQENVPAIFDNNRTFYTKLIGERNVA
LEHVTYGTMIRVLPRFSADGQIEMSLDIEDGNDKTPQSDTTTSVDALPEVGRTLISTIARVPHGKSLLVGGYTRDANTDT
VQSIPVLGKLPLIGSLFRYSSKNKSNVVRVFMIEPKEIVDPLTPDASESVNNILKQSGAWSGDDKLQKWVRVYLDRGQEV
IK
>Mature_562_residues
MKTHILLARVLACAALVLVAPGYSSEKIPVTGSGFVAKDDSLRTFFDAMALQLKEPVIVSKMAARKKITGNFEFHDPNAL
LEKLSLQLGLIWYFDGQAIYIYDASEMRNAVVSLRNVSLNEFNNFLKRSGLYNKNYPLRGDNRKGTFYVSGPPVYVDMVV
NAATMMDKQNDGIELGRQKIGVMRLNNTFVGDRTYNLRDQKMVIPGIATAIERLLQGEEQPLGNIVSSEPPAMPAFSANG
EKGKAANYAGGMSLQEALKQNAAAGNIKIVAYPDTNSLLVKGTAGQVHFIEMLVKALDVAKRHVELSLWIVDLNKSDLER
LGTSWSGSITIGDKLGVSLNQSSISTLDGSRFIAAVNALEEKKQATVVSRPVLLTQENVPAIFDNNRTFYTKLIGERNVA
LEHVTYGTMIRVLPRFSADGQIEMSLDIEDGNDKTPQSDTTTSVDALPEVGRTLISTIARVPHGKSLLVGGYTRDANTDT
VQSIPVLGKLPLIGSLFRYSSKNKSNVVRVFMIEPKEIVDPLTPDASESVNNILKQSGAWSGDDKLQKWVRVYLDRGQEV
IK

Specific function: Involved in the invasion of the cells of the intestinal epithelium. Could be necessary for the export of invasion related determinants [H]

COG id: COG1450

COG function: function code NU; Type II secretory pathway, component PulD

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=261, Percent_Identity=26.4367816091954, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005644
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR003522 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N [H]

EC number: NA

Molecular weight: Translated: 61645; Mature: 61645

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTHILLARVLACAALVLVAPGYSSEKIPVTGSGFVAKDDSLRTFFDAMALQLKEPVIVS
CCHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCEECCCHHHHHHHHHHHHHCCCHHHH
KMAARKKITGNFEFHDPNALLEKLSLQLGLIWYFDGQAIYIYDASEMRNAVVSLRNVSLN
HHHHHHHCCCCEEECCHHHHHHHHHHEEEEEEEECCEEEEEEEHHHHHHHHHHHHCCCHH
EFNNFLKRSGLYNKNYPLRGDNRKGTFYVSGPPVYVDMVVNAATMMDKQNDGIELGRQKI
HHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEEEHHHHHHHHCCCCCCHHHHHHHE
GVMRLNNTFVGDRTYNLRDQKMVIPGIATAIERLLQGEEQPLGNIVSSEPPAMPAFSANG
EEEEECCEEECCEEECCCCCEEECCHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCC
EKGKAANYAGGMSLQEALKQNAAAGNIKIVAYPDTNSLLVKGTAGQVHFIEMLVKALDVA
CCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHH
KRHVELSLWIVDLNKSDLERLGTSWSGSITIGDKLGVSLNQSSISTLDGSRFIAAVNALE
HHEEEEEEEEEECCHHHHHHCCCCCCCCEEECCCCCCEECCCHHCCCCCCHHHHHHHHHH
EKKQATVVSRPVLLTQENVPAIFDNNRTFYTKLIGERNVALEHVTYGTMIRVLPRFSADG
HHHHHHHHCCCEEEECCCCCEEEECCCEEEEEECCCCCCEEEHHHHHHHHHHHHCCCCCC
QIEMSLDIEDGNDKTPQSDTTTSVDALPEVGRTLISTIARVPHGKSLLVGGYTRDANTDT
EEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECEECCCCCCH
VQSIPVLGKLPLIGSLFRYSSKNKSNVVRVFMIEPKEIVDPLTPDASESVNNILKQSGAW
HHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCHHHHCCCCCCHHHHHHHHHHHCCCC
SGDDKLQKWVRVYLDRGQEVIK
CCHHHHHHHHHHHHHCCHHHCC
>Mature Secondary Structure
MKTHILLARVLACAALVLVAPGYSSEKIPVTGSGFVAKDDSLRTFFDAMALQLKEPVIVS
CCHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCEECCCHHHHHHHHHHHHHCCCHHHH
KMAARKKITGNFEFHDPNALLEKLSLQLGLIWYFDGQAIYIYDASEMRNAVVSLRNVSLN
HHHHHHHCCCCEEECCHHHHHHHHHHEEEEEEEECCEEEEEEEHHHHHHHHHHHHCCCHH
EFNNFLKRSGLYNKNYPLRGDNRKGTFYVSGPPVYVDMVVNAATMMDKQNDGIELGRQKI
HHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEEEHHHHHHHHCCCCCCHHHHHHHE
GVMRLNNTFVGDRTYNLRDQKMVIPGIATAIERLLQGEEQPLGNIVSSEPPAMPAFSANG
EEEEECCEEECCEEECCCCCEEECCHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCC
EKGKAANYAGGMSLQEALKQNAAAGNIKIVAYPDTNSLLVKGTAGQVHFIEMLVKALDVA
CCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHH
KRHVELSLWIVDLNKSDLERLGTSWSGSITIGDKLGVSLNQSSISTLDGSRFIAAVNALE
HHEEEEEEEEEECCHHHHHHCCCCCCCCEEECCCCCCEECCCHHCCCCCCHHHHHHHHHH
EKKQATVVSRPVLLTQENVPAIFDNNRTFYTKLIGERNVALEHVTYGTMIRVLPRFSADG
HHHHHHHHCCCEEEECCCCCEEEECCCEEEEEECCCCCCEEEHHHHHHHHHHHHCCCCCC
QIEMSLDIEDGNDKTPQSDTTTSVDALPEVGRTLISTIARVPHGKSLLVGGYTRDANTDT
EEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECEECCCCCCH
VQSIPVLGKLPLIGSLFRYSSKNKSNVVRVFMIEPKEIVDPLTPDASESVNNILKQSGAW
HHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCHHHHCCCCCCHHHHHHHHHHHCCCC
SGDDKLQKWVRVYLDRGQEVIK
CCHHHHHHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7868245; 7997169; 11677609 [H]