Click here to switch to the map view.

The map label for this gene is adrA [H]

Identifier: 29142865

GI number: 29142865

Start: 2550371

End: 2551483

Strand: Reverse

Name: adrA [H]

Synonym: t2479

Alternate gene names: 29142865

Gene position: 2551483-2550371 (Counterclockwise)

Preceding gene: 29142866

Following gene: 29142863

Centisome position: 53.25

GC content: 55.17

Gene sequence:

>1113_bases
ATGTTCCCAAAAATAATGAATGATGAAAATTTTTACCGAAAAGCGGTTGAGCAGGCGGTAGCGCCGCCTGACCCTTCTGA
TGATCGTCAGCGCTCCGGATTGCGCTTCGCCCGGCGCATCAGGCTACCGCGCGCGGTGGGGTTAGGGGGGATGCTTTTAC
CGGTGGCCGCCGTGTTAGTGTCGCAACCTGTCTTTGGCGGCTGGTGGTTATTGCTGGTCGGCTGGTCTTTTGTCTGGCCG
CATCTGGCGTGGCAGTGGGCGGCGAAAGCCCTTGATCCGCTACGCCAGGAAATTTACAACCTGAAAGTGGATGCGATCCT
CTCCGGCATGTGGATCGCGTTGATGGGCGTCAATATGTTGCCTGCCGCCGCGCTGTTTATGATGATGAGCATGAATCTGA
TGGGCGCTGGCGGGCGGCGGCTATTCACTGTCGGAATGGGCCTTTTGCTGGCGTCATGTCTGGTGACGTTGCAGCTTACC
GGGCTACCCGTCGCGATGCGAAGCTCGTCGCTGGAAGTCACGCTCTCTTTGCCCGTCATTATGTTGTATCCGCTTCTGTT
CGCCTGGGTAAGTTATCAAACGGCCATTAAATTAGCGGAACATAAGCGACGCTTGCAGGCGATGAGTTCGCGGGATGGCA
TGACCGGCGTCTATAACCGACGCCACTGGGAAATTTTATTACGTAATGAATTCGATCACAGCCGACGCCACCATCGGGAG
GCGACATTGTTGATTATCGATATCGATCATTTTAAGAGCATTAACGACACCTGGGGACATGATGCTGGGGATGAGGCTAT
TATCGCCCTGACGCGTCAATTACAGATAACGCTACGCGGGAGTGATATTATCGGGCGCTTTGGCGGCGACGAATTTGCGG
TGATTATGTGCGGAACGCCGGCAGACAGCGCGATTACCGCCATGTCGCGAGTGCATGAACGGCTAAATACCTTACGCTTG
CCGGGCGCGCCGCAGGTCATGTTACGTATCAGCGTGGGCGTGGCGCCGTTAACGCCACAAATCGGTCATTATCGGGAATG
GTTAAAGTCTGCGGATATGGCGCTTTACAAAGCAAAGAATGCCGGACGTAACCGCACCGAAGTGGCGGCATGA

Upstream 100 bases:

>100_bases
GCGGCGTAGTGCTATCGGGTGAGCCCTGAAAAACACTCACCCGAAATTTCATACTCCCTCCATGCGCTCTGTTTCTATAA
TTTGGGAAAATTGTTTCTAA

Downstream 100 bases:

>100_bases
CGTCCAGCCGGGCTTCAGGATTTACTGAGCGCCTCTGATTTTTCCATACATTTCGTCATCGCTTCTATTACCGCAGCGCG
GAAGCCACGTTCTTCCAGAA

Product: diguanylate cyclase AdrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MFPKIMNDENFYRKAVEQAVAPPDPSDDRQRSGLRFARRIRLPRAVGLGGMLLPVAAVLVSQPVFGGWWLLLVGWSFVWP
HLAWQWAAKALDPLRQEIYNLKVDAILSGMWIALMGVNMLPAAALFMMMSMNLMGAGGRRLFTVGMGLLLASCLVTLQLT
GLPVAMRSSSLEVTLSLPVIMLYPLLFAWVSYQTAIKLAEHKRRLQAMSSRDGMTGVYNRRHWEILLRNEFDHSRRHHRE
ATLLIIDIDHFKSINDTWGHDAGDEAIIALTRQLQITLRGSDIIGRFGGDEFAVIMCGTPADSAITAMSRVHERLNTLRL
PGAPQVMLRISVGVAPLTPQIGHYREWLKSADMALYKAKNAGRNRTEVAA

Sequences:

>Translated_370_residues
MFPKIMNDENFYRKAVEQAVAPPDPSDDRQRSGLRFARRIRLPRAVGLGGMLLPVAAVLVSQPVFGGWWLLLVGWSFVWP
HLAWQWAAKALDPLRQEIYNLKVDAILSGMWIALMGVNMLPAAALFMMMSMNLMGAGGRRLFTVGMGLLLASCLVTLQLT
GLPVAMRSSSLEVTLSLPVIMLYPLLFAWVSYQTAIKLAEHKRRLQAMSSRDGMTGVYNRRHWEILLRNEFDHSRRHHRE
ATLLIIDIDHFKSINDTWGHDAGDEAIIALTRQLQITLRGSDIIGRFGGDEFAVIMCGTPADSAITAMSRVHERLNTLRL
PGAPQVMLRISVGVAPLTPQIGHYREWLKSADMALYKAKNAGRNRTEVAA
>Mature_370_residues
MFPKIMNDENFYRKAVEQAVAPPDPSDDRQRSGLRFARRIRLPRAVGLGGMLLPVAAVLVSQPVFGGWWLLLVGWSFVWP
HLAWQWAAKALDPLRQEIYNLKVDAILSGMWIALMGVNMLPAAALFMMMSMNLMGAGGRRLFTVGMGLLLASCLVTLQLT
GLPVAMRSSSLEVTLSLPVIMLYPLLFAWVSYQTAIKLAEHKRRLQAMSSRDGMTGVYNRRHWEILLRNEFDHSRRHHRE
ATLLIIDIDHFKSINDTWGHDAGDEAIIALTRQLQITLRGSDIIGRFGGDEFAVIMCGTPADSAITAMSRVHERLNTLRL
PGAPQVMLRISVGVAPLTPQIGHYREWLKSADMALYKAKNAGRNRTEVAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=371, Percent_Identity=75.2021563342318, Blast_Score=589, Evalue=1e-170,
Organism=Escherichia coli, GI145693134, Length=161, Percent_Identity=35.4037267080745, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI87081881, Length=172, Percent_Identity=35.4651162790698, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1787262, Length=174, Percent_Identity=32.183908045977, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082007, Length=165, Percent_Identity=36.3636363636364, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788381, Length=167, Percent_Identity=31.7365269461078, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1787541, Length=167, Percent_Identity=33.5329341317365, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081977, Length=191, Percent_Identity=29.3193717277487, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787802, Length=162, Percent_Identity=29.6296296296296, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081974, Length=205, Percent_Identity=29.7560975609756, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788085, Length=183, Percent_Identity=30.0546448087432, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787816, Length=171, Percent_Identity=30.4093567251462, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788956, Length=173, Percent_Identity=27.7456647398844, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 41378; Mature: 41378

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPKIMNDENFYRKAVEQAVAPPDPSDDRQRSGLRFARRIRLPRAVGLGGMLLPVAAVLV
CCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHH
SQPVFGGWWLLLVGWSFVWPHLAWQWAAKALDPLRQEIYNLKVDAILSGMWIALMGVNML
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHH
PAAALFMMMSMNLMGAGGRRLFTVGMGLLLASCLVTLQLTGLPVAMRSSSLEVTLSLPVI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCHHH
MLYPLLFAWVSYQTAIKLAEHKRRLQAMSSRDGMTGVYNRRHWEILLRNEFDHSRRHHRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHCCC
ATLLIIDIDHFKSINDTWGHDAGDEAIIALTRQLQITLRGSDIIGRFGGDEFAVIMCGTP
EEEEEEEHHHCCCCCCCCCCCCCCHHHHEEEEEEEEEEECCCEEEECCCCCEEEEEECCC
ADSAITAMSRVHERLNTLRLPGAPQVMLRISVGVAPLTPQIGHYREWLKSADMALYKAKN
CHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHC
AGRNRTEVAA
CCCCCCCCCC
>Mature Secondary Structure
MFPKIMNDENFYRKAVEQAVAPPDPSDDRQRSGLRFARRIRLPRAVGLGGMLLPVAAVLV
CCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHH
SQPVFGGWWLLLVGWSFVWPHLAWQWAAKALDPLRQEIYNLKVDAILSGMWIALMGVNML
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHH
PAAALFMMMSMNLMGAGGRRLFTVGMGLLLASCLVTLQLTGLPVAMRSSSLEVTLSLPVI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCHHH
MLYPLLFAWVSYQTAIKLAEHKRRLQAMSSRDGMTGVYNRRHWEILLRNEFDHSRRHHRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHCCC
ATLLIIDIDHFKSINDTWGHDAGDEAIIALTRQLQITLRGSDIIGRFGGDEFAVIMCGTP
EEEEEEEHHHCCCCCCCCCCCCCCHHHHEEEEEEEEEEECCCEEEECCCCCEEEEEECCC
ADSAITAMSRVHERLNTLRLPGAPQVMLRISVGVAPLTPQIGHYREWLKSADMALYKAKN
CHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHC
AGRNRTEVAA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]