Definition | Salmonella enterica subsp. enterica serovar Typhi str. Ty2 chromosome, complete genome. |
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Accession | NC_004631 |
Length | 4,791,961 |
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The map label for this gene is fsr [H]
Identifier: 29142756
GI number: 29142756
Start: 2434614
End: 2435834
Strand: Direct
Name: fsr [H]
Synonym: t2367
Alternate gene names: 29142756
Gene position: 2434614-2435834 (Clockwise)
Preceding gene: 29142755
Following gene: 29142757
Centisome position: 50.81
GC content: 55.2
Gene sequence:
>1221_bases ATGGCCATGAGTGAACCAACCCAGCCGTTAGCCGGCGCGCCCGCAGCGGCCGCTAAAGCACGTACTTCGTTTGGTATTTT GGGCGCGATCAGTCTTTCCCATCTGCTGAACGATATGATCCAGTCGCTAATCTTAGCTATTTATCCCCTGTTGCAGGCGG AGTTTTCGCTGACTTTCGTCCAGATAGGTTTGATCACCCTGACGTTCCAGCTCGCCTCATCGCTACTGCAACCGGTCGTC GGCTACTGGACGGATAAATATCCCATGCCGTGGTCGCTGCCTGTCGGCATGTGTTTTACCCTGAGCGGGCTGGTACTGCT GGCAATGGCGGGAAGTTTTGGCGGCGTATTGCTCGCTGCGGCGCTGGTGGGTACCGGCTCGTCCGTTTTTCACCCGGAAT CGTCCCGCGTGGCGCGCATGGCCTCCGGCGGACGTCATGGTCTGGCGCAGTCTATCTTCCAGGTCGGCGGTAACTTCGGC AGTTCATTGGGCCCGCTGCTGGCCGCCGTGATTATCGCGCCCTATGGCAAAGGGAATGTCGCCTGGTTTGTGCTGGCCAC GCTGCTGGCGATCGTGGTGCTGGCGCAGATCAGCCGCTGGTATGCAGCCCAGCACCGGATAGCGAAAGGCAAGCCAAAAG CGATAATCGCTAACCCGCTGCCGCGCAATAAAGTCGTGCTGGCGGTCAGCGTGTTATTGCTACTCATTTTCTCGAAATAT TTCTATATGGCGAGCATCAGTAGCTACTACACCTTTTATCTGATGCAAAAATTCGGATTATCAATACAAAACGCGCAGCT CCATCTGTTTGCCTTCCTGTTTGCGGTGGCTGCCGGGACGGTTATCGGCGGGCCGGTGGGCGATAAAATCGGCAGAAAAT ATGTGATTTGGGGCTCTATTCTCGGCGTCGCGCCGTTTACCCTTGTTTTACCCTACGCCACGCTGTACTGGACGGGGATT TTAACGGTGATTATCGGCTTTATTCTCGCGTCGGCGTTTTCCGCCATTCTGGTGTATGCCCAAGAGCTGCTGCCAGGACG CATCGGCATGGTTTCCGGCCTGTTTTTCGGGTTTGCCTTCGGGATGGGAGGCCTGGGCGCAGCGGTGCTGGGGCTGATTG CAGACCATACCAGTATCTATTTAGTTTATAAAATCTGTGCTTTTCTGCCGCTTCTGGGGATACTGACCATATTCTTACCT GATAATCGACATAAAGCATGA
Upstream 100 bases:
>100_bases AATTGAGACTTCCTTCAAACACATTTCACAGGTATGTTAGGCAAGTAATAATTACACATCCTACTATCTCCAACATCGCA TAAAATTTAAGTGACTTTCT
Downstream 100 bases:
>100_bases TTTTATGGCGGTTAAAGGTATGCTTTAACCGCCTGTACATCCTGATGCCATCTTGCTTTGTCCATCCCATGCTTATCACT TTTACGTTCCATGCTCTTTT
Product: fosmidomycin resistance protein
Products: fosmidomycin [Periplasm]; Proton [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 406; Mature: 405
Protein sequence:
>406_residues MAMSEPTQPLAGAPAAAAKARTSFGILGAISLSHLLNDMIQSLILAIYPLLQAEFSLTFVQIGLITLTFQLASSLLQPVV GYWTDKYPMPWSLPVGMCFTLSGLVLLAMAGSFGGVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFG SSLGPLLAAVIIAPYGKGNVAWFVLATLLAIVVLAQISRWYAAQHRIAKGKPKAIIANPLPRNKVVLAVSVLLLLIFSKY FYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAVAAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLVLPYATLYWTGI LTVIIGFILASAFSAILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLIADHTSIYLVYKICAFLPLLGILTIFLP DNRHKA
Sequences:
>Translated_406_residues MAMSEPTQPLAGAPAAAAKARTSFGILGAISLSHLLNDMIQSLILAIYPLLQAEFSLTFVQIGLITLTFQLASSLLQPVV GYWTDKYPMPWSLPVGMCFTLSGLVLLAMAGSFGGVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFG SSLGPLLAAVIIAPYGKGNVAWFVLATLLAIVVLAQISRWYAAQHRIAKGKPKAIIANPLPRNKVVLAVSVLLLLIFSKY FYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAVAAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLVLPYATLYWTGI LTVIIGFILASAFSAILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLIADHTSIYLVYKICAFLPLLGILTIFLP DNRHKA >Mature_405_residues AMSEPTQPLAGAPAAAAKARTSFGILGAISLSHLLNDMIQSLILAIYPLLQAEFSLTFVQIGLITLTFQLASSLLQPVVG YWTDKYPMPWSLPVGMCFTLSGLVLLAMAGSFGGVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFGS SLGPLLAAVIIAPYGKGNVAWFVLATLLAIVVLAQISRWYAAQHRIAKGKPKAIIANPLPRNKVVLAVSVLLLLIFSKYF YMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAVAAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLVLPYATLYWTGIL TVIIGFILASAFSAILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLIADHTSIYLVYKICAFLPLLGILTIFLPD NRHKA
Specific function: Confers the resistance against fosmidomycin [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the major facilitator superfamily [H]
Homologues:
Organism=Escherichia coli, GI1786686, Length=405, Percent_Identity=93.3333333333333, Blast_Score=719, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020846 - InterPro: IPR011701 - InterPro: IPR016196 [H]
Pfam domain/function: PF07690 MFS_1 [H]
EC number: NA
Molecular weight: Translated: 43088; Mature: 42957
Theoretical pI: Translated: 10.16; Mature: 10.16
Prosite motif: PS50850 MFS
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAMSEPTQPLAGAPAAAAKARTSFGILGAISLSHLLNDMIQSLILAIYPLLQAEFSLTFV CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH QIGLITLTFQLASSLLQPVVGYWTDKYPMPWSLPVGMCFTLSGLVLLAMAGSFGGVLLAA HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH ALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFGSSLGPLLAAVIIAPYGKGNV HHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCH AWFVLATLLAIVVLAQISRWYAAQHRIAKGKPKAIIANPLPRNKVVLAVSVLLLLIFSKY HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHH FYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAVAAGTVIGGPVGDKIGRKYVIWGSI HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCEEEEEHHH LGVAPFTLVLPYATLYWTGILTVIIGFILASAFSAILVYAQELLPGRIGMVSGLFFGFAF HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH GMGGLGAAVLGLIADHTSIYLVYKICAFLPLLGILTIFLPDNRHKA CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC >Mature Secondary Structure AMSEPTQPLAGAPAAAAKARTSFGILGAISLSHLLNDMIQSLILAIYPLLQAEFSLTFV CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH QIGLITLTFQLASSLLQPVVGYWTDKYPMPWSLPVGMCFTLSGLVLLAMAGSFGGVLLAA HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH ALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFGSSLGPLLAAVIIAPYGKGNV HHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCH AWFVLATLLAIVVLAQISRWYAAQHRIAKGKPKAIIANPLPRNKVVLAVSVLLLLIFSKY HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHH FYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAVAAGTVIGGPVGDKIGRKYVIWGSI HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCEEEEEHHH LGVAPFTLVLPYATLYWTGILTVIIGFILASAFSAILVYAQELLPGRIGMVSGLFFGFAF HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH GMGGLGAAVLGLIADHTSIYLVYKICAFLPLLGILTIFLPDNRHKA CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: fosmidomycin [Cytoplasm]; Proton [Periplasm] [C]
Specific reaction: fosmidomycin [Cytoplasm] + Proton [Periplasm] = fosmidomycin [Periplasm] + Proton [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 8917080; 9278503 [H]