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The map label for this gene is uxaA [H]

Identifier: 29142618

GI number: 29142618

Start: 2282848

End: 2284020

Strand: Reverse

Name: uxaA [H]

Synonym: t2217

Alternate gene names: 29142618

Gene position: 2284020-2282848 (Counterclockwise)

Preceding gene: 29142619

Following gene: 29142617

Centisome position: 47.66

GC content: 52.43

Gene sequence:

>1173_bases
ATGATTATGAGCAATGAGACTTTTTTGGGTTTCCGACGCCCTGACGGCCGTTTTGGCATCCGTAATTATGTACTGATTTT
ACCTACCAGCGTTTGTGCGAATAAAGTTGCCCAGGATATTGCCCGGCAGGTAAAAGGTGCGACATGGGTGAATAACGATT
TTGGCTGCTGCCAGGTGGCAGGCGATGCGCGTCTGACGGAAAAGACATTGATTAATGTGGCGAATAATCCCAACGTCGGC
GCTATTGTGGTTGTGGGCTTAGGCTGTGAAGGCGCGGAGCCGCTGCGCATCGCAGAAGAGATTACCGCATTTGGCAAACC
GACCTCCTGCATTACCATTCAGGAAGAGGGCGGCACGCTTAAATGTCAGGCCAGGGGGATTTCGCTGGCCCGCGACTATG
CGCAACAACTCTCCATGCAAAAACCGCAGCAAGCACCGGTTAGCGAGCTGCTGCTGGCGATGGAGTGCGGCGGGTCAGAT
ACGACATCGGGGCTGGCGTCTAACCCTTCCTGCGGGGTCGCCTCGGATAAGCTGATACGCTGCGGCGGAAGCTCAATTCT
TTCTGAAACGACGGAATTTATTGGCGCCGAGCATGTGATGGCGAAACGCGCGGTGACGCCGGAGGTTGGTCAACAGCTCA
TTGATTTAGTGGTCGGCTGTGAGGCGCGAGCAAAAGCGCTGGGCGAGGATATTCGCGGGGGACAGCCGACGCCGGGCAGT
ATTAAAGGCGGGCTGACTACCATTGAAGAAAAATCGTTAGGTTGTATGCATAAAGCGGGTCATGCGCCGCTACAGGGCGT
ACTGGAATATGCCGATAGTCCAACGCATCCGGGCCTGTGGATTATGGATACCCCAGGGCAGGATATTGAATCTATTTCCG
GCATGGTGGCGGGTGGAGCGCAGATCGTTATTTTTACTACCGGTCGCGGAACGCCTGCCGGTAACCCAATAGCGCCGGTA
ATAAAAATTACGGGTAATAAAGCAACGTGGGAAATGATGCAGGACAATATTGATATTGATGTGTCCGCCATTATGTCTGG
CGAGGCTTCTATTACGCAAATGGGCGAGGAAATTTATCAGGAAATTTTACGCGTCGCGAATGGGAAAACGACTAAATCAG
AAGATTTAGGTCATAACGAATTCTCTATTTATAAGATCGCGCCGACGTTCTGA

Upstream 100 bases:

>100_bases
CGCGCCACTCAGGAAATAAAAAGTGGCGACTATGTGCACGTCCACAATGTGGAAAGCGAACGCGGACGTGGTGACTGGAA
ATAATATAAAACAAGGGAAA

Downstream 100 bases:

>100_bases
TACCAAATCGGGCAGCACAAGCTGTCCGGTTATCTCCTGGGAATAAGCTATGAAAATTAAAAAAACACTGGAACGTTTTC
CTGGTGGTATGATGGTTGTA

Product: truncated hydrolase

Products: NA

Alternate protein names: Altronic acid hydratase [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MIMSNETFLGFRRPDGRFGIRNYVLILPTSVCANKVAQDIARQVKGATWVNNDFGCCQVAGDARLTEKTLINVANNPNVG
AIVVVGLGCEGAEPLRIAEEITAFGKPTSCITIQEEGGTLKCQARGISLARDYAQQLSMQKPQQAPVSELLLAMECGGSD
TTSGLASNPSCGVASDKLIRCGGSSILSETTEFIGAEHVMAKRAVTPEVGQQLIDLVVGCEARAKALGEDIRGGQPTPGS
IKGGLTTIEEKSLGCMHKAGHAPLQGVLEYADSPTHPGLWIMDTPGQDIESISGMVAGGAQIVIFTTGRGTPAGNPIAPV
IKITGNKATWEMMQDNIDIDVSAIMSGEASITQMGEEIYQEILRVANGKTTKSEDLGHNEFSIYKIAPTF

Sequences:

>Translated_390_residues
MIMSNETFLGFRRPDGRFGIRNYVLILPTSVCANKVAQDIARQVKGATWVNNDFGCCQVAGDARLTEKTLINVANNPNVG
AIVVVGLGCEGAEPLRIAEEITAFGKPTSCITIQEEGGTLKCQARGISLARDYAQQLSMQKPQQAPVSELLLAMECGGSD
TTSGLASNPSCGVASDKLIRCGGSSILSETTEFIGAEHVMAKRAVTPEVGQQLIDLVVGCEARAKALGEDIRGGQPTPGS
IKGGLTTIEEKSLGCMHKAGHAPLQGVLEYADSPTHPGLWIMDTPGQDIESISGMVAGGAQIVIFTTGRGTPAGNPIAPV
IKITGNKATWEMMQDNIDIDVSAIMSGEASITQMGEEIYQEILRVANGKTTKSEDLGHNEFSIYKIAPTF
>Mature_390_residues
MIMSNETFLGFRRPDGRFGIRNYVLILPTSVCANKVAQDIARQVKGATWVNNDFGCCQVAGDARLTEKTLINVANNPNVG
AIVVVGLGCEGAEPLRIAEEITAFGKPTSCITIQEEGGTLKCQARGISLARDYAQQLSMQKPQQAPVSELLLAMECGGSD
TTSGLASNPSCGVASDKLIRCGGSSILSETTEFIGAEHVMAKRAVTPEVGQQLIDLVVGCEARAKALGEDIRGGQPTPGS
IKGGLTTIEEKSLGCMHKAGHAPLQGVLEYADSPTHPGLWIMDTPGQDIESISGMVAGGAQIVIFTTGRGTPAGNPIAPV
IKITGNKATWEMMQDNIDIDVSAIMSGEASITQMGEEIYQEILRVANGKTTKSEDLGHNEFSIYKIAPTF

Specific function: D-galactarate metabolism; first step. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789516, Length=404, Percent_Identity=33.6633663366337, Blast_Score=208, Evalue=4e-55,
Organism=Escherichia coli, GI1789475, Length=391, Percent_Identity=33.5038363171356, Blast_Score=202, Evalue=4e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.7 [H]

Molecular weight: Translated: 41168; Mature: 41168

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMSNETFLGFRRPDGRFGIRNYVLILPTSVCANKVAQDIARQVKGATWVNNDFGCCQVA
CCCCCCCEEEEECCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCEEECCCCCEEEEC
GDARLTEKTLINVANNPNVGAIVVVGLGCEGAEPLRIAEEITAFGKPTSCITIQEEGGTL
CCCCCCHHHEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEECCCEE
KCQARGISLARDYAQQLSMQKPQQAPVSELLLAMECGGSDTTSGLASNPSCGVASDKLIR
EEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
CGGSSILSETTEFIGAEHVMAKRAVTPEVGQQLIDLVVGCEARAKALGEDIRGGQPTPGS
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
IKGGLTTIEEKSLGCMHKAGHAPLQGVLEYADSPTHPGLWIMDTPGQDIESISGMVAGGA
CCCCCEEEHHHHCCHHHHCCCCHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHEECCCC
QIVIFTTGRGTPAGNPIAPVIKITGNKATWEMMQDNIDIDVSAIMSGEASITQMGEEIYQ
EEEEEECCCCCCCCCCCCEEEEEECCCCEEHHHHCCCCEEEEEEECCCHHHHHHHHHHHH
EILRVANGKTTKSEDLGHNEFSIYKIAPTF
HHHHHHCCCCCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MIMSNETFLGFRRPDGRFGIRNYVLILPTSVCANKVAQDIARQVKGATWVNNDFGCCQVA
CCCCCCCEEEEECCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCEEECCCCCEEEEC
GDARLTEKTLINVANNPNVGAIVVVGLGCEGAEPLRIAEEITAFGKPTSCITIQEEGGTL
CCCCCCHHHEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEECCCEE
KCQARGISLARDYAQQLSMQKPQQAPVSELLLAMECGGSDTTSGLASNPSCGVASDKLIR
EEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
CGGSSILSETTEFIGAEHVMAKRAVTPEVGQQLIDLVVGCEARAKALGEDIRGGQPTPGS
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
IKGGLTTIEEKSLGCMHKAGHAPLQGVLEYADSPTHPGLWIMDTPGQDIESISGMVAGGA
CCCCCEEEHHHHCCHHHHCCCCHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHEECCCC
QIVIFTTGRGTPAGNPIAPVIKITGNKATWEMMQDNIDIDVSAIMSGEASITQMGEEIYQ
EEEEEECCCCCCCCCCCCEEEEEECCCCEEHHHHCCCCEEEEEEECCCHHHHHHHHHHHH
EILRVANGKTTKSEDLGHNEFSIYKIAPTF
HHHHHHCCCCCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]