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The map label for this gene is modF [H]

Identifier: 29142524

GI number: 29142524

Start: 2172119

End: 2173594

Strand: Direct

Name: modF [H]

Synonym: t2109

Alternate gene names: 29142524

Gene position: 2172119-2173594 (Clockwise)

Preceding gene: 29142523

Following gene: 29142525

Centisome position: 45.33

GC content: 54.95

Gene sequence:

>1476_bases
ATGTCATCGTTGCAAATTTCGCAAGGCACGTTTCGTCTGAGCGATACAAAAACACTTCATCTGGATTCGCTGACGCTCAA
TGCGGGCGATAGCTGGGCATTCGTTGGGGCTAACGGGAGCGGGAAGTCGGCGCTCGCCCGCGCGCTGGCGGGTGAACTGC
CATTATTAACAGGCGAGCGCCAGTGTCAGTTTACCCGCATTACCCGTCTGTCCTTTGAACAATTGCAAAAGCTGGTCAGC
GATGAGTGGCAACGTAATAACACCGATATGCTCAGTCCTGGCGAAGACGATACCGGGCGCACTACCGCGGAAATTATTCA
GGATGATGTTCACCATCCTGCCCGCTATGCGATGCTGGCGCAGCAGTTTGGCATTTCCGCTTTACTCAACAGGCGTTTTA
AATACCTTTCTACCGGCGAGACGCGAAAAGCGCTGCTGTGTCAGGCGCTGATGTCTGAGCCGGAGTTATTAATCCTTGAT
GAACCGTTCGACGGACTTGACGTGACCGCCCGTCAACAACTGGCACAACGCCTGACGGCGTTGAACCAGGCGGGTATGAC
CCTGGCGCTGGTACTCAACCGTTTTGATGAGATCCCGGACTTCGTGCAGTTTGCCGGCGTGCTTGCCGACTGTACGCTGG
CGGAGACCGGAACGACGGCAGAGTTACTGCAACGGGCGTTGGTCGCTCAACTCGCGCACAGCGAGCGTCTGACCGACGTA
CAATTACCCGAACCGGACGAACCTTCCGCCCGCCATGCGTTACCCGATGGCGAACCACGGATCGTACTTAACGATGGCGT
AGTCTCGTATAACGATCGCCCTATCCTCCACCACCTAAGCTGGCGAGTCAATCCGGGCGAACACTGGCAGATCGTCGGTC
CTAACGGAGCGGGTAAGTCTACGTTGCTTAGCCTTATTACTGGCGATCATCCGCAAGGCTACAGCAACGATCTTACGCTG
TTCGGGCGGCGGCGAGGAAGCGGCGAAACAATCTGGGATATCAAAAAACATATCGGCTACGTCAGCAGCAGTTTACATCT
GGATTACCGCGTCAGTACCACGGTACGCAATGTCATTCTCTCCGGCTATTTCGATTCTATCGGCATTTACCAGGCCGTTT
CAGACAGGCAACGAAAACTGGCGCAACAGTGGCTGGATATTCTGGGAATCGATAAGCGTACGGCGGATGCCCCCTTCCAC
AGTCTCTCTTGGGGACAGCAGCGGCTGGCGCTAATCGTGCGCGCGCTGGTTAAACATCCGACAGTGTTGATTCTGGATGA
GCCGCTGCAAGGGTTGGACCCGCTGAACCGCCAACTGGTACGCCGTTTTGTGGATGTATTAATTCGCCAGGGAGAGACTC
AACTGCTGTTCGTTTCCCATCATGCAGAGGATGCGCCTGCCTGTATTACCCACCGGCTGGAATTTGTACCAGAGGGCGAA
CGTTATAAGTACGTTTCCGGACGATGCAATAATTAA

Upstream 100 bases:

>100_bases
GCGGACAGAGTGATTATTGCAACGTTGTGCTAAGCACATTGACATCCGTTGCCGAAAGACGTATCCCTGTCATTCATCGC
TGCAAAAAATGGGATGCAAA

Downstream 100 bases:

>100_bases
ATGTATTATCAGAATGGCGCCGCGCGCCATTCTGGAACCACTCTCCTTTTATTAAGAATAATAATAACGGTCGATAAGCT
TACTATCTCTTGAATCGCTG

Product: molybdenum transport ATP-binding protein ModF

Products: NA

Alternate protein names: Photorepair protein PhrA [H]

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MSSLQISQGTFRLSDTKTLHLDSLTLNAGDSWAFVGANGSGKSALARALAGELPLLTGERQCQFTRITRLSFEQLQKLVS
DEWQRNNTDMLSPGEDDTGRTTAEIIQDDVHHPARYAMLAQQFGISALLNRRFKYLSTGETRKALLCQALMSEPELLILD
EPFDGLDVTARQQLAQRLTALNQAGMTLALVLNRFDEIPDFVQFAGVLADCTLAETGTTAELLQRALVAQLAHSERLTDV
QLPEPDEPSARHALPDGEPRIVLNDGVVSYNDRPILHHLSWRVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTL
FGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQRKLAQQWLDILGIDKRTADAPFH
SLSWGQQRLALIVRALVKHPTVLILDEPLQGLDPLNRQLVRRFVDVLIRQGETQLLFVSHHAEDAPACITHRLEFVPEGE
RYKYVSGRCNN

Sequences:

>Translated_491_residues
MSSLQISQGTFRLSDTKTLHLDSLTLNAGDSWAFVGANGSGKSALARALAGELPLLTGERQCQFTRITRLSFEQLQKLVS
DEWQRNNTDMLSPGEDDTGRTTAEIIQDDVHHPARYAMLAQQFGISALLNRRFKYLSTGETRKALLCQALMSEPELLILD
EPFDGLDVTARQQLAQRLTALNQAGMTLALVLNRFDEIPDFVQFAGVLADCTLAETGTTAELLQRALVAQLAHSERLTDV
QLPEPDEPSARHALPDGEPRIVLNDGVVSYNDRPILHHLSWRVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTL
FGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQRKLAQQWLDILGIDKRTADAPFH
SLSWGQQRLALIVRALVKHPTVLILDEPLQGLDPLNRQLVRRFVDVLIRQGETQLLFVSHHAEDAPACITHRLEFVPEGE
RYKYVSGRCNN
>Mature_490_residues
SSLQISQGTFRLSDTKTLHLDSLTLNAGDSWAFVGANGSGKSALARALAGELPLLTGERQCQFTRITRLSFEQLQKLVSD
EWQRNNTDMLSPGEDDTGRTTAEIIQDDVHHPARYAMLAQQFGISALLNRRFKYLSTGETRKALLCQALMSEPELLILDE
PFDGLDVTARQQLAQRLTALNQAGMTLALVLNRFDEIPDFVQFAGVLADCTLAETGTTAELLQRALVAQLAHSERLTDVQ
LPEPDEPSARHALPDGEPRIVLNDGVVSYNDRPILHHLSWRVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTLF
GRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQRKLAQQWLDILGIDKRTADAPFHS
LSWGQQRLALIVRALVKHPTVLILDEPLQGLDPLNRQLVRRFVDVLIRQGETQLLFVSHHAEDAPACITHRLEFVPEGER
YKYVSGRCNN

Specific function: Involved in the transport of molybdenum into the cell. Involved in photorepair. Could act on UV-induced DNA damage other than pyrimidine dimers [H]

COG id: COG1119

COG function: function code P; ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI27262624, Length=193, Percent_Identity=26.4248704663212, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI27262626, Length=193, Percent_Identity=26.4248704663212, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1786975, Length=485, Percent_Identity=88.4536082474227, Blast_Score=881, Evalue=0.0,
Organism=Escherichia coli, GI48994943, Length=380, Percent_Identity=27.6315789473684, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87081782, Length=534, Percent_Identity=24.5318352059925, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI145693107, Length=501, Percent_Identity=25.5489021956088, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788897, Length=499, Percent_Identity=22.8456913827655, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788506, Length=500, Percent_Identity=25.6, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787041, Length=521, Percent_Identity=22.4568138195777, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI48995001, Length=475, Percent_Identity=23.7894736842105, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790525, Length=489, Percent_Identity=21.6768916155419, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1789991, Length=482, Percent_Identity=22.8215767634855, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790190, Length=469, Percent_Identity=24.3070362473348, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787792, Length=481, Percent_Identity=24.3243243243243, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788165, Length=228, Percent_Identity=29.8245614035088, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786253, Length=209, Percent_Identity=33.4928229665072, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787029, Length=206, Percent_Identity=30.5825242718447, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790544, Length=228, Percent_Identity=30.2631578947368, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788225, Length=209, Percent_Identity=28.2296650717703, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789593, Length=222, Percent_Identity=27.9279279279279, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786319, Length=192, Percent_Identity=29.6875, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788472, Length=454, Percent_Identity=21.1453744493392, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082268, Length=196, Percent_Identity=28.0612244897959, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786703, Length=200, Percent_Identity=31.5, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787112, Length=227, Percent_Identity=29.0748898678414, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789864, Length=216, Percent_Identity=25, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787089, Length=213, Percent_Identity=28.169014084507, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1786563, Length=199, Percent_Identity=28.643216080402, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=280, Percent_Identity=27.8571428571429, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320266, Length=396, Percent_Identity=29.2929292929293, Blast_Score=159, Evalue=8e-40,
Organism=Drosophila melanogaster, GI19920532, Length=183, Percent_Identity=30.6010928961749, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24580930, Length=183, Percent_Identity=30.6010928961749, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28574744, Length=235, Percent_Identity=25.9574468085106, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24650853, Length=197, Percent_Identity=29.9492385786802, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650855, Length=197, Percent_Identity=29.9492385786802, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281362751, Length=197, Percent_Identity=29.9492385786802, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 54747; Mature: 54616

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLQISQGTFRLSDTKTLHLDSLTLNAGDSWAFVGANGSGKSALARALAGELPLLTGER
CCCCCCCCCEEEECCCCEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCC
QCQFTRITRLSFEQLQKLVSDEWQRNNTDMLSPGEDDTGRTTAEIIQDDVHHPARYAMLA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
QQFGISALLNRRFKYLSTGETRKALLCQALMSEPELLILDEPFDGLDVTARQQLAQRLTA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LNQAGMTLALVLNRFDEIPDFVQFAGVLADCTLAETGTTAELLQRALVAQLAHSERLTDV
HHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
QLPEPDEPSARHALPDGEPRIVLNDGVVSYNDRPILHHLSWRVNPGEHWQIVGPNGAGKS
CCCCCCCCCCCCCCCCCCCEEEEECCEEEECCCCEEEEEEEEECCCCCEEEECCCCCCHH
TLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVIL
HHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHH
SGYFDSIGIYQAVSDRQRKLAQQWLDILGIDKRTADAPFHSLSWGQQRLALIVRALVKHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TVLILDEPLQGLDPLNRQLVRRFVDVLIRQGETQLLFVSHHAEDAPACITHRLEFVPEGE
EEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCC
RYKYVSGRCNN
CEEEECCCCCC
>Mature Secondary Structure 
SSLQISQGTFRLSDTKTLHLDSLTLNAGDSWAFVGANGSGKSALARALAGELPLLTGER
CCCCCCCCEEEECCCCEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCC
QCQFTRITRLSFEQLQKLVSDEWQRNNTDMLSPGEDDTGRTTAEIIQDDVHHPARYAMLA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
QQFGISALLNRRFKYLSTGETRKALLCQALMSEPELLILDEPFDGLDVTARQQLAQRLTA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LNQAGMTLALVLNRFDEIPDFVQFAGVLADCTLAETGTTAELLQRALVAQLAHSERLTDV
HHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
QLPEPDEPSARHALPDGEPRIVLNDGVVSYNDRPILHHLSWRVNPGEHWQIVGPNGAGKS
CCCCCCCCCCCCCCCCCCCEEEEECCEEEECCCCEEEEEEEEECCCCCEEEECCCCCCHH
TLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVIL
HHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHH
SGYFDSIGIYQAVSDRQRKLAQQWLDILGIDKRTADAPFHSLSWGQQRLALIVRALVKHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TVLILDEPLQGLDPLNRQLVRRFVDVLIRQGETQLLFVSHHAEDAPACITHRLEFVPEGE
EEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCC
RYKYVSGRCNN
CEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8564363; 8550508; 8905232; 9278503; 8310005 [H]