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The map label for this gene is artM [H]

Identifier: 29142429

GI number: 29142429

Start: 2067082

End: 2067750

Strand: Direct

Name: artM [H]

Synonym: t2008

Alternate gene names: 29142429

Gene position: 2067082-2067750 (Clockwise)

Preceding gene: 29142428

Following gene: 29142430

Centisome position: 43.14

GC content: 52.77

Gene sequence:

>669_bases
ATGCTTGAGTACTTACCTGAACTGCTAAAAGGGCTACACACCAGCCTGACGCTGACCGTGGCTTCTATTGCCGTCGCTTT
GGTGCTGGCGTTAGTTTTTACCATCATCCTGACGCTAAAAACGCCGTTCGTGGTGTGGCTGGTGCGCGGCTATATCACGT
TGTTTACCGGTACGCCGTTGTTGGTGCAAATTTTCCTGATCTACTACGGACCCGGTCAATTCCCGACACTGCAAGAGTAT
CCGCTACTCTGGCATCTACTGTCTGAACCGTGGCTGTGCGCACTGATCGCGTTGTCGCTAAACAGCGCCGCTTACACCAC
GCAGCTATTTTATGGCGCGATTCGCGCGATTCCGGAAGGTCAGTGGCAGTCCTGCGGCGCGCTGGGGATGAGTAAGAAAG
ATACGCTGGCGATTTTGTTGCCCTATGCGTTTAAACGCGCCCTCTCCTCCTATTCTAATGAGGTGGTACTGGTCTTCAAA
AGTACCTCGCTGGCCTATACCATCACCTTGATGGAGGTCATGGGGTACAGTCAGTTGCTCTATGGTCGTACCTACGATGT
GGTGGTATTTGGCGCGGCAGGCGTAATTTACCTGGTCGTCAACGGTCTATTGACGCTGATGATGCGTTTGATTGAGCGTA
AAGCCCTGGCGTTTGAGCGGCGCAATTAA

Upstream 100 bases:

>100_bases
TTATTGCGGCGGCTATTTACCTGGTCATTACGCTGATCAGTCAGTACATTCTCAAACGCATAGACCTGCGCGCAACACGT
TTTGAGCGGAGGCCGGACTA

Downstream 100 bases:

>100_bases
CCAGGCAGGATAAGGCATTCTCGCCGCCGTTCGACAATGGTCAGATGGCGCTGCGCTTATCAAGCCTACGATGCATAATA
TTGAATAAACCCGACGGACA

Product: arginine transporter permease ArtM

Products: ADP; phosphate; L-arginine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MLEYLPELLKGLHTSLTLTVASIAVALVLALVFTIILTLKTPFVVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEY
PLLWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCGALGMSKKDTLAILLPYAFKRALSSYSNEVVLVFK
STSLAYTITLMEVMGYSQLLYGRTYDVVVFGAAGVIYLVVNGLLTLMMRLIERKALAFERRN

Sequences:

>Translated_222_residues
MLEYLPELLKGLHTSLTLTVASIAVALVLALVFTIILTLKTPFVVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEY
PLLWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCGALGMSKKDTLAILLPYAFKRALSSYSNEVVLVFK
STSLAYTITLMEVMGYSQLLYGRTYDVVVFGAAGVIYLVVNGLLTLMMRLIERKALAFERRN
>Mature_222_residues
MLEYLPELLKGLHTSLTLTVASIAVALVLALVFTIILTLKTPFVVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEY
PLLWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCGALGMSKKDTLAILLPYAFKRALSSYSNEVVLVFK
STSLAYTITLMEVMGYSQLLYGRTYDVVVFGAAGVIYLVVNGLLTLMMRLIERKALAFERRN

Specific function: Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4160

COG function: function code E; ABC-type arginine/histidine transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787086, Length=222, Percent_Identity=94.1441441441441, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1788226, Length=223, Percent_Identity=34.0807174887892, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788645, Length=208, Percent_Identity=33.1730769230769, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787087, Length=237, Percent_Identity=29.535864978903, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787030, Length=213, Percent_Identity=27.2300469483568, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1788646, Length=210, Percent_Identity=27.6190476190476, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1786874, Length=218, Percent_Identity=26.1467889908257, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786873, Length=216, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24776; Mature: 24776

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEYLPELLKGLHTSLTLTVASIAVALVLALVFTIILTLKTPFVVWLVRGYITLFTGTPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LVQIFLIYYGPGQFPTLQEYPLLWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEG
HHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
QWQSCGALGMSKKDTLAILLPYAFKRALSSYSNEVVLVFKSTSLAYTITLMEVMGYSQLL
CCCCCCCCCCCCCCHHEEEHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
YGRTYDVVVFGAAGVIYLVVNGLLTLMMRLIERKALAFERRN
HCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLEYLPELLKGLHTSLTLTVASIAVALVLALVFTIILTLKTPFVVWLVRGYITLFTGTPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LVQIFLIYYGPGQFPTLQEYPLLWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEG
HHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
QWQSCGALGMSKKDTLAILLPYAFKRALSSYSNEVVLVFKSTSLAYTITLMEVMGYSQLL
CCCCCCCCCCCCCCHHEEEHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
YGRTYDVVVFGAAGVIYLVVNGLLTLMMRLIERKALAFERRN
HCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-arginine [Periplasm]; H2O [C]

Specific reaction: ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]