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The map label for this gene is ycbL [H]

Identifier: 29142361

GI number: 29142361

Start: 1982216

End: 1982863

Strand: Reverse

Name: ycbL [H]

Synonym: t1937

Alternate gene names: 29142361

Gene position: 1982863-1982216 (Counterclockwise)

Preceding gene: 29142362

Following gene: 29142356

Centisome position: 41.38

GC content: 55.25

Gene sequence:

>648_bases
ATGAACTATCGTATTATTCCGGTCACCGCGTTCTCCCAGAACTGTTCATTAATCTGGTGCGAACAAACCCGGCTGGCGGC
GCTGGTCGATCCGGGCGGCGACGCGGAAAAAATTAAACAGGAAGTGGACGCCAGCGGCGTGACGTTGATGCAAATTTTAC
TCACGCATGGGCATCTCGATCATGTCGGCGCGGCGAGTGAACTGGCGCAGCATTACGGCGTTCCTGTTATCGGTCCGGAA
AAAGAAGATGAGTTCTGGCTGCAAGGACTGCCGGCGCAAAGCCGCATGTTTGGTCTGGATGAGTGTCAGCCGCTGACGCC
TGATCGCTGGCTGAACGACGGCGATCGCGTCAGCGTGGGGAATGTGACGTTACAGGTGTTACATTGTCCGGGACACACGC
CGGGACACGTGGTTTTCTTTGATGAACAGTCGCAACTGCTGATCTCCGGCGATGTGATTTTCAAAGGTGGCGTCGGGCGC
AGCGATTTTCCTCGCGGCGATCACACCCAGTTGATTGACGCCATTAAGCGTAAATTATTGCCGCTTGGCGATGATGTGAC
CTTTATTCCTGGCCACGGCCCGCTCTCTACGCTCGGATACGAGCGTCTGCATAATTCCTTCCTGCAAGATGAGATGCCGG
TCTGGTAA

Upstream 100 bases:

>100_bases
CGCAGGTGGTGTAGGATATTACCCACGTAGTAACTTTGTGCATATTGATACCGGGCCAGCGCGGCACTGGTAATCAGCGA
GGCTTAATCAAAGGAGCAGT

Downstream 100 bases:

>100_bases
GCAGAATGAAAAAGCCTGCAATGTGCAGGCTTTTTTATCGGTCACGCCAGTCGGCAGCTTTTTATAGTACCGCGACAATG
GCTTCGCACAGCGGCGCCAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGVTLMQILLTHGHLDHVGAASELAQHYGVPVIGPE
KEDEFWLQGLPAQSRMFGLDECQPLTPDRWLNDGDRVSVGNVTLQVLHCPGHTPGHVVFFDEQSQLLISGDVIFKGGVGR
SDFPRGDHTQLIDAIKRKLLPLGDDVTFIPGHGPLSTLGYERLHNSFLQDEMPVW

Sequences:

>Translated_215_residues
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGVTLMQILLTHGHLDHVGAASELAQHYGVPVIGPE
KEDEFWLQGLPAQSRMFGLDECQPLTPDRWLNDGDRVSVGNVTLQVLHCPGHTPGHVVFFDEQSQLLISGDVIFKGGVGR
SDFPRGDHTQLIDAIKRKLLPLGDDVTFIPGHGPLSTLGYERLHNSFLQDEMPVW
>Mature_215_residues
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGVTLMQILLTHGHLDHVGAASELAQHYGVPVIGPE
KEDEFWLQGLPAQSRMFGLDECQPLTPDRWLNDGDRVSVGNVTLQVLHCPGHTPGHVVFFDEQSQLLISGDVIFKGGVGR
SDFPRGDHTQLIDAIKRKLLPLGDDVTFIPGHGPLSTLGYERLHNSFLQDEMPVW

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI21703352, Length=196, Percent_Identity=32.1428571428571, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI116642887, Length=196, Percent_Identity=32.1428571428571, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI41327741, Length=203, Percent_Identity=27.5862068965517, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787158, Length=215, Percent_Identity=91.1627906976744, Blast_Score=412, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23727; Mature: 23727

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGVTLMQILLTHGHLD
CCEEEEEEEEECCCCCEEEECCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHCCCCC
HVGAASELAQHYGVPVIGPEKEDEFWLQGLPAQSRMFGLDECQPLTPDRWLNDGDRVSVG
CCCCHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHCCCCCCCCCCCHHCCCCCCEEEEC
NVTLQVLHCPGHTPGHVVFFDEQSQLLISGDVIFKGGVGRSDFPRGDHTQLIDAIKRKLL
CEEEEEEECCCCCCCEEEEECCCCCEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHHC
PLGDDVTFIPGHGPLSTLGYERLHNSFLQDEMPVW
CCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGVTLMQILLTHGHLD
CCEEEEEEEEECCCCCEEEECCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHCCCCC
HVGAASELAQHYGVPVIGPEKEDEFWLQGLPAQSRMFGLDECQPLTPDRWLNDGDRVSVG
CCCCHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHCCCCCCCCCCCHHCCCCCCEEEEC
NVTLQVLHCPGHTPGHVVFFDEQSQLLISGDVIFKGGVGRSDFPRGDHTQLIDAIKRKLL
CEEEEEEECCCCCCCEEEEECCCCCEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHHC
PLGDDVTFIPGHGPLSTLGYERLHNSFLQDEMPVW
CCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]