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The map label for this gene is rpiR [C]

Identifier: 29142225

GI number: 29142225

Start: 1854566

End: 1855447

Strand: Direct

Name: rpiR [C]

Synonym: t1794

Alternate gene names: 29142225

Gene position: 1854566-1855447 (Clockwise)

Preceding gene: 29142224

Following gene: 29142228

Centisome position: 38.7

GC content: 49.55

Gene sequence:

>882_bases
ATGGAGCCTCAACCCCCACGTCTTAAACCCGGAAAAATCCTTGACACTCTGGGTGCTATGCAAAAAAGCCTGACACGTGC
CTCCCAGCGTATTGCGCAATATATTTTAGCCTTCCCCAGACAGGTGACACAGTCATCTATTGCCGATTTGTCGCGCGACA
CACAGGCCGGAGAAGCCACGGTTATTCGCTTTTGTCGCACCCTGGGCTATAAAGGTTTTCAGGATTTTAAAATGGACCTG
GCCATTGAACTTGCCACTACCGAGTCTGATGACAGTAGTCCTCTACTGGATGCCGAAGTTAGCGAATCCGACGATGCCCA
CGCCATTGGTTTAAAATTGCAGAACACCATTAGTAATGTATTATCTGAAACGCTAAATCTGCTTGATATGCAACAGGTTC
TCGGTGTCGTGGACGCCCTACGTCACTGTCACTCAGTTTATATCTTTGGTGTGGGCTCATCGGGGATCACGGCGCTGGAT
ATGAAACACAAGCTAATGCGTATTGGTTTACGGGGCGATGCGGTAAGCAATAACCATTTTATGTACATGCAGGCTACGCT
ATTAAAAGCAGGCGATGTCGCGATGGGTGTCAGTCACTCGGGCACATCGCCAGAAACAGTGCATTCACTCCGATTGGCCC
GACAGGCTGGCGCCACCACAGTCGCCATTACCCATAATCTGGGTTCTCCATTATGTGAAGAGGCCGATTTTTGCCTGATC
AATGGTAATCGGCAAGGAATGTTGCAGGGTGACTCGATCGGTACGAAAGCCGCGCAGCTTTTCGTCTTTGACCTGCTCTA
TACCCTTCTTGTACAGTCCTCGCCGGAACAGGCCCGAGAAAGCAAATTACGGACAATGAATGCCCTGGACATGACAAAAT
AA

Upstream 100 bases:

>100_bases
CTTACATCGCGCTTTTTTTCATGCCGCAGACTTGATAGGCTCTGCTCTGTTCGATATTGCAGGCTTTGTGCCGCAATCAG
CCCTCAAGAGCAGGAACTAT

Downstream 100 bases:

>100_bases
TTCCCTTCACGTACAGGCGTCATTTTCCTTTTTTGTCCATGAGTCTGCTGGACGCTTTATAGACAACAAAGCCCGGTCTC
CCGGGCTCTGAAAGTCAATG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MEPQPPRLKPGKILDTLGAMQKSLTRASQRIAQYILAFPRQVTQSSIADLSRDTQAGEATVIRFCRTLGYKGFQDFKMDL
AIELATTESDDSSPLLDAEVSESDDAHAIGLKLQNTISNVLSETLNLLDMQQVLGVVDALRHCHSVYIFGVGSSGITALD
MKHKLMRIGLRGDAVSNNHFMYMQATLLKAGDVAMGVSHSGTSPETVHSLRLARQAGATTVAITHNLGSPLCEEADFCLI
NGNRQGMLQGDSIGTKAAQLFVFDLLYTLLVQSSPEQARESKLRTMNALDMTK

Sequences:

>Translated_293_residues
MEPQPPRLKPGKILDTLGAMQKSLTRASQRIAQYILAFPRQVTQSSIADLSRDTQAGEATVIRFCRTLGYKGFQDFKMDL
AIELATTESDDSSPLLDAEVSESDDAHAIGLKLQNTISNVLSETLNLLDMQQVLGVVDALRHCHSVYIFGVGSSGITALD
MKHKLMRIGLRGDAVSNNHFMYMQATLLKAGDVAMGVSHSGTSPETVHSLRLARQAGATTVAITHNLGSPLCEEADFCLI
NGNRQGMLQGDSIGTKAAQLFVFDLLYTLLVQSSPEQARESKLRTMNALDMTK
>Mature_293_residues
MEPQPPRLKPGKILDTLGAMQKSLTRASQRIAQYILAFPRQVTQSSIADLSRDTQAGEATVIRFCRTLGYKGFQDFKMDL
AIELATTESDDSSPLLDAEVSESDDAHAIGLKLQNTISNVLSETLNLLDMQQVLGVVDALRHCHSVYIFGVGSSGITALD
MKHKLMRIGLRGDAVSNNHFMYMQATLLKAGDVAMGVSHSGTSPETVHSLRLARQAGATTVAITHNLGSPLCEEADFCLI
NGNRQGMLQGDSIGTKAAQLFVFDLLYTLLVQSSPEQARESKLRTMNALDMTK

Specific function: Regulatory Protein Involved In Rpib Gene Repression. Also Involved In Als Operon Repression. [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI87082369, Length=278, Percent_Identity=26.2589928057554, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788767, Length=251, Percent_Identity=29.4820717131474, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788159, Length=277, Percent_Identity=27.7978339350181, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082130, Length=265, Percent_Identity=26.0377358490566, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31842; Mature: 31842

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPQPPRLKPGKILDTLGAMQKSLTRASQRIAQYILAFPRQVTQSSIADLSRDTQAGEAT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VIRFCRTLGYKGFQDFKMDLAIELATTESDDSSPLLDAEVSESDDAHAIGLKLQNTISNV
HHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHH
LSETLNLLDMQQVLGVVDALRHCHSVYIFGVGSSGITALDMKHKLMRIGLRGDAVSNNHF
HHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEECCCEE
MYMQATLLKAGDVAMGVSHSGTSPETVHSLRLARQAGATTVAITHNLGSPLCEEADFCLI
EEEEEEHHCCCCEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEEE
NGNRQGMLQGDSIGTKAAQLFVFDLLYTLLVQSSPEQARESKLRTMNALDMTK
ECCCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEPQPPRLKPGKILDTLGAMQKSLTRASQRIAQYILAFPRQVTQSSIADLSRDTQAGEAT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VIRFCRTLGYKGFQDFKMDLAIELATTESDDSSPLLDAEVSESDDAHAIGLKLQNTISNV
HHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHH
LSETLNLLDMQQVLGVVDALRHCHSVYIFGVGSSGITALDMKHKLMRIGLRGDAVSNNHF
HHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEECCCEE
MYMQATLLKAGDVAMGVSHSGTSPETVHSLRLARQAGATTVAITHNLGSPLCEEADFCLI
EEEEEEHHCCCCEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEEE
NGNRQGMLQGDSIGTKAAQLFVFDLLYTLLVQSSPEQARESKLRTMNALDMTK
ECCCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]