Click here to switch to the map view.

The map label for this gene is sirB1

Identifier: 29141575

GI number: 29141575

Start: 1187422

End: 1188231

Strand: Direct

Name: sirB1

Synonym: t1103

Alternate gene names: 29141575

Gene position: 1187422-1188231 (Clockwise)

Preceding gene: 29141574

Following gene: 29141576

Centisome position: 24.78

GC content: 49.14

Gene sequence:

>810_bases
ATGAGGTCGTTAGCTGATTTCGAATTTAACAATGCGCCGCTGTGTGATGGCATGATCCTGGCATCAGAGATGATTCGCCT
GGATTTTCCCACGCAGTTTGTCTACGACGAACTGGAACGTCTGGTCAGTCTGGCGCAGGAAGAAATTAGCCAGCTCCTGT
CTCAGGATGAGCAACTGGAAAAATTGCTGGCACTTTTTTACGGCGAGTGGGGGTTCACGGATTCCCGCGGCGTCTACCGT
CTTTCTGATGCTTTATGGCTCGATAAAGTCCTGAAAAAACGCCAGGGGAGCGCTGTATCGTTGGGCGCTATTTTATTATG
GATAGCAAACCGTCTTGATTTGCCGTTGGTGCCCGTTATCTTCCCAACGCAGCTGATTTTGCGTATTGAATCGCTGGAAG
GAGAAATGTGGCTGATTAACCCGTTCAACGGTGAAACGCTTGATGAACATACCCTCGAAGTCTGGTTAAAAGGCAATATT
AGTCCGGTCGCCGAGTTGTTTAACGAAGATTTGGACGAAGCGGATAACGCCGAAGTGATTCGTAAGCTACTGGATACGCT
GAAATCCTCGCTGATGGAGGAACGGCAAATGGAGCTGGCGCTGCGCGTTAGCGAAGCATTGTTGCAATTTAACCCGGAAG
ATCCTTACGAAATCCGTGACCGCGGGTTGATCTACGCGCAGCTTGAGTGTGAACACGTTGCGCTGACTGATTTAAGCTAC
TTCGTTGAACAGTGTCCGGAAGACCCGATCAGCGAAATGATTCGTGCGCAGATCAACACCATTGCGCACAAGCAAATTGT
TCTACATTAA

Upstream 100 bases:

>100_bases
CAGCCAGCAGGCGCGTTTTATCGCTTTCCCGCTGGCGCTGGTGGTGCTGTACATCATCATTAAACTCGCCACCACAAAAA
TACCGTTACTGGGGTAAGTC

Downstream 100 bases:

>100_bases
TTAACCGACATTTTACCTATAAGTGTAAGGCGATCCTATGAAACAAAAAGTGGTTAACATTGGCGACATTAAGGTGGCAA
ATGACCTGCCGTTTGTGCTG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MRSLADFEFNNAPLCDGMILASEMIRLDFPTQFVYDELERLVSLAQEEISQLLSQDEQLEKLLALFYGEWGFTDSRGVYR
LSDALWLDKVLKKRQGSAVSLGAILLWIANRLDLPLVPVIFPTQLILRIESLEGEMWLINPFNGETLDEHTLEVWLKGNI
SPVAELFNEDLDEADNAEVIRKLLDTLKSSLMEERQMELALRVSEALLQFNPEDPYEIRDRGLIYAQLECEHVALTDLSY
FVEQCPEDPISEMIRAQINTIAHKQIVLH

Sequences:

>Translated_269_residues
MRSLADFEFNNAPLCDGMILASEMIRLDFPTQFVYDELERLVSLAQEEISQLLSQDEQLEKLLALFYGEWGFTDSRGVYR
LSDALWLDKVLKKRQGSAVSLGAILLWIANRLDLPLVPVIFPTQLILRIESLEGEMWLINPFNGETLDEHTLEVWLKGNI
SPVAELFNEDLDEADNAEVIRKLLDTLKSSLMEERQMELALRVSEALLQFNPEDPYEIRDRGLIYAQLECEHVALTDLSY
FVEQCPEDPISEMIRAQINTIAHKQIVLH
>Mature_269_residues
MRSLADFEFNNAPLCDGMILASEMIRLDFPTQFVYDELERLVSLAQEEISQLLSQDEQLEKLLALFYGEWGFTDSRGVYR
LSDALWLDKVLKKRQGSAVSLGAILLWIANRLDLPLVPVIFPTQLILRIESLEGEMWLINPFNGETLDEHTLEVWLKGNI
SPVAELFNEDLDEADNAEVIRKLLDTLKSSLMEERQMELALRVSEALLQFNPEDPYEIRDRGLIYAQLECEHVALTDLSY
FVEQCPEDPISEMIRAQINTIAHKQIVLH

Specific function: Not essential for the expression of the invasive phenotype. Required for maximal expression of sirC

COG id: COG2912

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0162 family

Homologues:

Organism=Escherichia coli, GI1787465, Length=269, Percent_Identity=85.8736059479554, Blast_Score=471, Evalue=1e-134,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SIRB1_SALTI (P0A2M0)

Other databases:

- EMBL:   AL627271
- EMBL:   AE014613
- RefSeq:   NP_456283.1
- RefSeq:   NP_804917.1
- GeneID:   1070465
- GeneID:   1248257
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t1103
- KEGG:   sty:STY1898
- HOGENOM:   HBG644081
- OMA:   FINPWDG
- ProtClustDB:   PRK10941
- BioCyc:   SENT209261:T1103-MONOMER
- BioCyc:   SENT220341:STY1898-MONOMER
- GO:   GO:0005488
- InterPro:   IPR011990
- Gene3D:   G3DSA:1.25.40.10

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 30925; Mature: 30925

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLADFEFNNAPLCDGMILASEMIRLDFPTQFVYDELERLVSLAQEEISQLLSQDEQLE
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KLLALFYGEWGFTDSRGVYRLSDALWLDKVLKKRQGSAVSLGAILLWIANRLDLPLVPVI
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHH
FPTQLILRIESLEGEMWLINPFNGETLDEHTLEVWLKGNISPVAELFNEDLDEADNAEVI
HHHHHHHHHHCCCCCEEEEECCCCCCCCCHHEEEEECCCCHHHHHHHHHHCCCCCCHHHH
RKLLDTLKSSLMEERQMELALRVSEALLQFNPEDPYEIRDRGLIYAQLECEHVALTDLSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEEECCHHHHHHHHH
FVEQCPEDPISEMIRAQINTIAHKQIVLH
HHHHCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRSLADFEFNNAPLCDGMILASEMIRLDFPTQFVYDELERLVSLAQEEISQLLSQDEQLE
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KLLALFYGEWGFTDSRGVYRLSDALWLDKVLKKRQGSAVSLGAILLWIANRLDLPLVPVI
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHH
FPTQLILRIESLEGEMWLINPFNGETLDEHTLEVWLKGNISPVAELFNEDLDEADNAEVI
HHHHHHHHHHCCCCCEEEEECCCCCCCCCHHEEEEECCCCHHHHHHHHHHCCCCCCHHHH
RKLLDTLKSSLMEERQMELALRVSEALLQFNPEDPYEIRDRGLIYAQLECEHVALTDLSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEEECCHHHHHHHHH
FVEQCPEDPISEMIRAQINTIAHKQIVLH
HHHHCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504