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The map label for this gene is mltE [H]

Identifier: 29141553

GI number: 29141553

Start: 1160902

End: 1161513

Strand: Direct

Name: mltE [H]

Synonym: t1078

Alternate gene names: 29141553

Gene position: 1160902-1161513 (Clockwise)

Preceding gene: 29141550

Following gene: 29141555

Centisome position: 24.23

GC content: 52.94

Gene sequence:

>612_bases
GTGAAATTAAGATGGTTTGCTTTTTTGGTAGTAATACTGGCTGGCTGTAGCTCAAAACAGGATTACAGGAATCCACCGTG
GAATGCCGAAGTGCCTGTAAAGCGTGCGATGCAGTGGATGCCCATCAGTGAAAAAGCCGGGGCGGCATGGGGGGTTGATC
CACATTTAATCACCGCGATTATCGCCATTGAATCCGGCGGCAACCCTAACGCGGTCAGTAAGTCCAATGCGATTGGCCTG
ATGCAGTTAAAGGCGTCGACTTCCGGGCGCGACGTTTACCGTCGTATGGGCTGGCGTGGCGAACCGACCACCAGCGAGCT
GAAAAACCCTGAGCGTAACATCTCAATGGGCGCGGCGTATCTGAGCATTCTGGAAAATGGGCCGCTGGCCGGCATCAAAG
ATCCGCAGGTGATGCAATATGCGCTGGTCGTCTCTTATGCTAACGGCGCAGGCGCGTTATTGCGTACTTTTTCATCCGAC
AGGAAGAAGGCGATAGAAAAAATTAACGATCTGGATGCTGACGAGTTTTTTGAACATGTTGTTGATAATCATCCCGCGCC
GCAGGCGCCGCGCTATATCTGGAAGCTTCAGCAGGCGCTGGACGCCATGTAG

Upstream 100 bases:

>100_bases
TGCGACGTTTCTGGATGCGCACCAGGGAGGCAACCTAAGTACCTGGCCGGGGCGGTATAACCTCTTCGGCAGATAAGTTA
CGGCTATAAGGATAGATGAC

Downstream 100 bases:

>100_bases
TTTAGCGTGAAGATTATTCTCGCACTTTATTCGCTCTTTCTCGGGCGTCGCGCTCAAGCGAAAAAATAATCCGCTGCAAC
TCCCGCTCCACCGCCGGGCT

Product: membrane-bound lytic murein transglycosylase E

Products: NA

Alternate protein names: Peptidoglycan lytic endotransglycosylase [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MKLRWFAFLVVILAGCSSKQDYRNPPWNAEVPVKRAMQWMPISEKAGAAWGVDPHLITAIIAIESGGNPNAVSKSNAIGL
MQLKASTSGRDVYRRMGWRGEPTTSELKNPERNISMGAAYLSILENGPLAGIKDPQVMQYALVVSYANGAGALLRTFSSD
RKKAIEKINDLDADEFFEHVVDNHPAPQAPRYIWKLQQALDAM

Sequences:

>Translated_203_residues
MKLRWFAFLVVILAGCSSKQDYRNPPWNAEVPVKRAMQWMPISEKAGAAWGVDPHLITAIIAIESGGNPNAVSKSNAIGL
MQLKASTSGRDVYRRMGWRGEPTTSELKNPERNISMGAAYLSILENGPLAGIKDPQVMQYALVVSYANGAGALLRTFSSD
RKKAIEKINDLDADEFFEHVVDNHPAPQAPRYIWKLQQALDAM
>Mature_203_residues
MKLRWFAFLVVILAGCSSKQDYRNPPWNAEVPVKRAMQWMPISEKAGAAWGVDPHLITAIIAIESGGNPNAVSKSNAIGL
MQLKASTSGRDVYRRMGWRGEPTTSELKNPERNISMGAAYLSILENGPLAGIKDPQVMQYALVVSYANGAGALLRTFSSD
RKKAIEKINDLDADEFFEHVVDNHPAPQAPRYIWKLQQALDAM

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain [H]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI87081855, Length=203, Percent_Identity=90.1477832512315, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI87082191, Length=166, Percent_Identity=40.3614457831325, Blast_Score=139, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 22427; Mature: 22427

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRWFAFLVVILAGCSSKQDYRNPPWNAEVPVKRAMQWMPISEKAGAAWGVDPHLITAI
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHCCCCCCCCHHHEEEE
IAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWRGEPTTSELKNPERNISMGAAY
EEEECCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHH
LSILENGPLAGIKDPQVMQYALVVSYANGAGALLRTFSSDRKKAIEKINDLDADEFFEHV
HHHHHCCCCCCCCCHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VDNHPAPQAPRYIWKLQQALDAM
HCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLRWFAFLVVILAGCSSKQDYRNPPWNAEVPVKRAMQWMPISEKAGAAWGVDPHLITAI
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHCCCCCCCCHHHEEEE
IAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWRGEPTTSELKNPERNISMGAAY
EEEECCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHH
LSILENGPLAGIKDPQVMQYALVVSYANGAGALLRTFSSDRKKAIEKINDLDADEFFEHV
HHHHHCCCCCCCCCHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VDNHPAPQAPRYIWKLQQALDAM
HCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA