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The map label for this gene is kdgR [H]

Identifier: 29141511

GI number: 29141511

Start: 1121070

End: 1121861

Strand: Direct

Name: kdgR [H]

Synonym: t1036

Alternate gene names: 29141511

Gene position: 1121070-1121861 (Clockwise)

Preceding gene: 29141510

Following gene: 29141513

Centisome position: 23.39

GC content: 49.62

Gene sequence:

>792_bases
ATGGCAAACGCAGATCTGGATAAGCAGCCTGATTCTGTATCTTCTGTGCTGAAAGTTTTCGGCATTCTGCAGGCGCTGGG
TGAAGAGCGTGAAATAGGGATTACCGAGCTATCGCAGCGCGTCATGATGTCGAAAAGCACCGTTTATCGCTTTTTGCAAA
CCATGAAAACGCTGGGCTACGTGGCTCAGGAGGGGGAGTCTGAAAAATACTCTCTGACGCTAAAGCTGTTTGAGCTGGGC
GCGCGAGCTTTGCAAAATGTTGATCTCATCCGCAGTGCGGACATTCAGATGCGCGAACTGTCTCGTCTGACAAAAGAAAC
TATCCATCTTGGCGCGCTGGATGAAGACAGCATTGTCTATATCCATAAAATTGACTCTATGTACAATCTGCGGATGTACT
CACGTATTGGGCGTCGTAATCCGCTGTACAGTACGGCCATCGGTAAAGTGCTTCTGGCCTGGCGCGACCGTGATGAGGTT
AAGCAGATTCTCGACGGCGTAGAGTATAAGCAAAGCACGGGACGCACGATTACCAGCACTGAAGCGTTGCTGCCGCTGTT
GGATGAAGTGCGTGCGCAAGGCTACGGTGAAGATAACGAAGAACAGGAAGAAGGGTTACGTTGTATCGGCGTACCGGTAT
TTGACCGTTTTGGCGTAGTCATCGCAGGGTTAAGCATTTCGTTCCCGACGCTGCGTTTTTCAGAAGAACGCCTACAGGAA
TATGTGGCTATGTTACACGTCGCCGCGCGTAAAATTTCTGAACAAATGGGTTACAACGATTATCCCTTCTAA

Upstream 100 bases:

>100_bases
TTGTAACGAAGTAAGCAAAGATGGATTGCGGGCGACCTGGCGTGAAATTATAATAAAAACTCGTTCTGAATTTTATAAAA
CGCTCGTAATGAGGTGATAA

Downstream 100 bases:

>100_bases
GCAACGTTATTAGCATGACGTTAAAAAAAAGCAGCTACATTTTTCGTAGCTGCTTTTTTTATAACATCGGGTGGGATGAA
ATCGTAAAAGTAGATAATAT

Product: transcriptional regulator KdgR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELG
ARALQNVDLIRSADIQMRELSRLTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRDEV
KQILDGVEYKQSTGRTITSTEALLPLLDEVRAQGYGEDNEEQEEGLRCIGVPVFDRFGVVIAGLSISFPTLRFSEERLQE
YVAMLHVAARKISEQMGYNDYPF

Sequences:

>Translated_263_residues
MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELG
ARALQNVDLIRSADIQMRELSRLTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRDEV
KQILDGVEYKQSTGRTITSTEALLPLLDEVRAQGYGEDNEEQEEGLRCIGVPVFDRFGVVIAGLSISFPTLRFSEERLQE
YVAMLHVAARKISEQMGYNDYPF
>Mature_262_residues
ANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELGA
RALQNVDLIRSADIQMRELSRLTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRDEVK
QILDGVEYKQSTGRTITSTEALLPLLDEVRAQGYGEDNEEQEEGLRCIGVPVFDRFGVVIAGLSISFPTLRFSEERLQEY
VAMLHVAARKISEQMGYNDYPF

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=263, Percent_Identity=96.1977186311787, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1786468, Length=247, Percent_Identity=40.4858299595142, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1789999, Length=228, Percent_Identity=32.8947368421053, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1790752, Length=226, Percent_Identity=31.4159292035398, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI87082359, Length=244, Percent_Identity=29.0983606557377, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786715, Length=229, Percent_Identity=29.2576419213974, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788581, Length=222, Percent_Identity=32.4324324324324, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29892; Mature: 29760

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKTLGY
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAQEGESEKYSLTLKLFELGARALQNVDLIRSADIQMRELSRLTKETIHLGALDEDSIVY
HHHCCCCCHHEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEE
IHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRDEVKQILDGVEYKQSTGRTITST
EEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEECHH
EALLPLLDEVRAQGYGEDNEEQEEGLRCIGVPVFDRFGVVIAGLSISFPTLRFSEERLQE
HHHHHHHHHHHHCCCCCCCCHHHCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
YVAMLHVAARKISEQMGYNDYPF
HHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKTLGY
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAQEGESEKYSLTLKLFELGARALQNVDLIRSADIQMRELSRLTKETIHLGALDEDSIVY
HHHCCCCCHHEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEE
IHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRDEVKQILDGVEYKQSTGRTITST
EEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEECHH
EALLPLLDEVRAQGYGEDNEEQEEGLRCIGVPVFDRFGVVIAGLSISFPTLRFSEERLQE
HHHHHHHHHHHHCCCCCCCCHHHCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
YVAMLHVAARKISEQMGYNDYPF
HHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]