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The map label for this gene is yegH [H]

Identifier: 29141255

GI number: 29141255

Start: 841068

End: 842648

Strand: Reverse

Name: yegH [H]

Synonym: t0753

Alternate gene names: 29141255

Gene position: 842648-841068 (Counterclockwise)

Preceding gene: 29141295

Following gene: 29141251

Centisome position: 17.58

GC content: 54.21

Gene sequence:

>1581_bases
ATGGAATGGATTGCCGATCCGTCAATCTGGGCCGGACTGGTAACGTTAATCGTTATCGAACTTGTTCTCGGCATTGATAA
CCTGGTCTTTATTGCCATCCTCGCTGAAAAACTACCGCCGGGGCAGCGCGACCGCGCGCGCATTACCGGCCTGATACTGG
CGATGATCATGCGCCTGCTGCTGCTGGCGTCAATCTCGTGGCTGGTCACCTTGACTAAGCCGCTCTTTAGCGTACAGGCG
TTAAGCTTTAGCGCCCGCGATCTGATTATGCTGTTCGGCGGCTTCTTCCTGCTCTTTAAAGCCACCATGGAGCTCAACGA
ACGGCTGGAAGGGAAAGATAGCGCCAACCCTACCCAGCGTAAGGGGGCGAAATTCTGGGCGGTGGTCGCGCAAATAGTGG
TGCTGGACGCTATCTTTTCTCTCGACTCCGTGATTACCGCCGTGGGGATGGTCGATCACCTAGCGGTCATGATGGCGGCC
GTGATAATCGCCATTAGCCTGATGCTGCTCGCCAGCAAGTCCCTGACCCGATTTGTGAACAACCATCCCACCATTGTCAT
TTTGTGCCTTAGCTTCCTGCTAATGATCGGCTTTAGCCTGGTGGCGGAAGGGTTTGGTTTCCACATTCCGAAAGGGTATC
TGTACGCGGCTATCGGCTTCTCGGTGATGATCGAGGCGCTCAACCAACTGGCTATTTTTAACCGCCGCCGTTTTCTTTCC
GCTAACCATACGCTGCGCCAGCGCACAACGGAGGCCGTGATGCGGCTGATTAGCGGTAAAAAAGAGGATGCCGAACTGGA
TGCGGAAACCGCCGCGATGCTGGCAGACCATGACGACAGCCAGATTTTTAATCCGCAGGAGCGCAGGATGATTGAGCGGG
TGCTGAATCTCAACCAGCGCACCGTAAGTAGCATCATGACGTCGCGTCACGATATCGAGCATATCGATCTCAACGCGCCG
GAAGCGGAAATCCGCGCTCTGCTGGAAAAGAACCAGCATACGCGTCTGGTCGTGACGGGTGAAAATGAACAGGAAGATTT
ACTCGGCGTCGTCCACGTCATCGATCTGTTGCAACAATCGCTGCGCGGCGAACCGCTCAACCTGCGGGCGCTGATTCGCC
AACCGCTGGTTTTCCCGGAAACATTGCCGCTGCTGCCTGCGCTGGAGCAGTTCCGTAACGCCAGAACCCATTTTGCCTTT
GTCGTAGATGAGTTTGGCTCGGTTGAAGGCATTGTGACATTAAGCGATGTCATGGAGACTATCGCCGGTAATCTGCCGAA
TGAAGTCGAGGAAATTGACGCCCGCCACGATATTCAGAAGAACCCGGACAGTTCCTGGACAGCAAACGGCCATATGCCGC
TGGAGGATTTGGTGCAGTACGTGCCGCTACCGCTGGATGAAAAACGGGAATACCATACGATTGCCGGATTATTGATGGAA
TATTTGCAACGCATACCGCAAACCGGTGAAGAGGTTCAGGTGGGCGATTATTTGCTGAAAACATTGCAGGTAGAAAGCCA
TCGAGTGCAGAAAGTGCAGTTAATTCCGCTGCATAACGGCGAGCCAGACCAGGAGATGTAA

Upstream 100 bases:

>100_bases
GTAACAAAGATAAATTGCTCTGCGGCATTGCATTTTTCCGCCGTATTATCCATGATCGAATTGTGACAATTGTCATATTA
CAGAAGGTATTGCTCTTACT

Downstream 100 bases:

>100_bases
CGTCTGTTCGCCTGCCCCGGCCTGCTTACCAGGCAGGCCGGAGGCGCGTTAGCCTCGCCATCCGGCTCTGCCCTTTGGCC
AAAAACTACAGCTTATTCAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MEWIADPSIWAGLVTLIVIELVLGIDNLVFIAILAEKLPPGQRDRARITGLILAMIMRLLLLASISWLVTLTKPLFSVQA
LSFSARDLIMLFGGFFLLFKATMELNERLEGKDSANPTQRKGAKFWAVVAQIVVLDAIFSLDSVITAVGMVDHLAVMMAA
VIIAISLMLLASKSLTRFVNNHPTIVILCLSFLLMIGFSLVAEGFGFHIPKGYLYAAIGFSVMIEALNQLAIFNRRRFLS
ANHTLRQRTTEAVMRLISGKKEDAELDAETAAMLADHDDSQIFNPQERRMIERVLNLNQRTVSSIMTSRHDIEHIDLNAP
EAEIRALLEKNQHTRLVVTGENEQEDLLGVVHVIDLLQQSLRGEPLNLRALIRQPLVFPETLPLLPALEQFRNARTHFAF
VVDEFGSVEGIVTLSDVMETIAGNLPNEVEEIDARHDIQKNPDSSWTANGHMPLEDLVQYVPLPLDEKREYHTIAGLLME
YLQRIPQTGEEVQVGDYLLKTLQVESHRVQKVQLIPLHNGEPDQEM

Sequences:

>Translated_526_residues
MEWIADPSIWAGLVTLIVIELVLGIDNLVFIAILAEKLPPGQRDRARITGLILAMIMRLLLLASISWLVTLTKPLFSVQA
LSFSARDLIMLFGGFFLLFKATMELNERLEGKDSANPTQRKGAKFWAVVAQIVVLDAIFSLDSVITAVGMVDHLAVMMAA
VIIAISLMLLASKSLTRFVNNHPTIVILCLSFLLMIGFSLVAEGFGFHIPKGYLYAAIGFSVMIEALNQLAIFNRRRFLS
ANHTLRQRTTEAVMRLISGKKEDAELDAETAAMLADHDDSQIFNPQERRMIERVLNLNQRTVSSIMTSRHDIEHIDLNAP
EAEIRALLEKNQHTRLVVTGENEQEDLLGVVHVIDLLQQSLRGEPLNLRALIRQPLVFPETLPLLPALEQFRNARTHFAF
VVDEFGSVEGIVTLSDVMETIAGNLPNEVEEIDARHDIQKNPDSSWTANGHMPLEDLVQYVPLPLDEKREYHTIAGLLME
YLQRIPQTGEEVQVGDYLLKTLQVESHRVQKVQLIPLHNGEPDQEM
>Mature_526_residues
MEWIADPSIWAGLVTLIVIELVLGIDNLVFIAILAEKLPPGQRDRARITGLILAMIMRLLLLASISWLVTLTKPLFSVQA
LSFSARDLIMLFGGFFLLFKATMELNERLEGKDSANPTQRKGAKFWAVVAQIVVLDAIFSLDSVITAVGMVDHLAVMMAA
VIIAISLMLLASKSLTRFVNNHPTIVILCLSFLLMIGFSLVAEGFGFHIPKGYLYAAIGFSVMIEALNQLAIFNRRRFLS
ANHTLRQRTTEAVMRLISGKKEDAELDAETAAMLADHDDSQIFNPQERRMIERVLNLNQRTVSSIMTSRHDIEHIDLNAP
EAEIRALLEKNQHTRLVVTGENEQEDLLGVVHVIDLLQQSLRGEPLNLRALIRQPLVFPETLPLLPALEQFRNARTHFAF
VVDEFGSVEGIVTLSDVMETIAGNLPNEVEEIDARHDIQKNPDSSWTANGHMPLEDLVQYVPLPLDEKREYHTIAGLLME
YLQRIPQTGEEVQVGDYLLKTLQVESHRVQKVQLIPLHNGEPDQEM

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=340, Percent_Identity=22.3529411764706, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI87082033, Length=527, Percent_Identity=90.3225806451613, Blast_Score=940, Evalue=0.0,
Organism=Escherichia coli, GI1788119, Length=526, Percent_Identity=50, Blast_Score=459, Evalue=1e-130,
Organism=Escherichia coli, GI1789197, Length=226, Percent_Identity=50.8849557522124, Blast_Score=218, Evalue=9e-58,
Organism=Escherichia coli, GI1790664, Length=238, Percent_Identity=31.9327731092437, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1786879, Length=263, Percent_Identity=27.3764258555133, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI145693175, Length=277, Percent_Identity=25.2707581227437, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005496
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF03741 TerC [H]

EC number: NA

Molecular weight: Translated: 59005; Mature: 59005

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MEWIADPSIWAGLVTLIVIELVLGIDNLVFIAILAEKLPPGQRDRARITGLILAMIMRLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LLASISWLVTLTKPLFSVQALSFSARDLIMLFGGFFLLFKATMELNERLEGKDSANPTQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
KGAKFWAVVAQIVVLDAIFSLDSVITAVGMVDHLAVMMAAVIIAISLMLLASKSLTRFVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NHPTIVILCLSFLLMIGFSLVAEGFGFHIPKGYLYAAIGFSVMIEALNQLAIFNRRRFLS
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANHTLRQRTTEAVMRLISGKKEDAELDAETAAMLADHDDSQIFNPQERRMIERVLNLNQR
CCHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHH
TVSSIMTSRHDIEHIDLNAPEAEIRALLEKNQHTRLVVTGENEQEDLLGVVHVIDLLQQS
HHHHHHHHCCCCCEECCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
LRGEPLNLRALIRQPLVFPETLPLLPALEQFRNARTHFAFVVDEFGSVEGIVTLSDVMET
HCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEHHHHHHH
IAGNLPNEVEEIDARHDIQKNPDSSWTANGHMPLEDLVQYVPLPLDEKREYHTIAGLLME
HHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHH
YLQRIPQTGEEVQVGDYLLKTLQVESHRVQKVQLIPLHNGEPDQEM
HHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]